Further analysis of the connected moments expansion

We apply the connected moments expansion to simple quantum--mechanical examples and show that under some conditions the main equations of the approach are no longer valid. In particular we consider two--level systems, the harmonic oscillator and the pure quartic oscillator.Comment: 19 pages; 2 tables; 4 figure

Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010)

Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by acquiring mobile elements such as transposons, plasmids, and phages. In this study, we compared two genomes of A. baumannii clinical strains isolated in 2000 (ST-2_clon_2000) and 2010 (ST-2_clon_2010) from GenBank project PRJNA308422

Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives

Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen. This explains the increasing interest showed by many groups of research and pharmaceutical companies to find compounds with potential to disrupt at least one of the steps within the angiogenic process. Hydroxytyrosol (3,4-dihydroxyphenyl ethanol) has been identified as the most important health-related phenolic compound of virgin olive oil because of its pleiotropic effects on multiple targets. In 2012, our group identified hydroxytyrosol as an anti-angiogenic compound able to inhibit several key steps in the angiogenic process. In the present study, the potential effects of six hydroxytyrosol derivatives are tested and compared with those exhibited by hydroxytyrosol by making use of several in vitro and in vivo assays. Results indicate that these are candidate new anti-angiogenic compounds with potential utility in anti-tumor and anti-angiogenic therapies.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech [Our experimental work is supported by grants BIO2014-56092-R (MINECO and FEDER) and P12-CTS-1507 (Andalusian Government and FEDER) and funds from group BIO-267 (Andalusian Government). The "CIBER de Enfermedades Raras" is an initiative from the ISCIII (Spain)]. This communication has the support of a travel grant

Sustainable management of peel waste in the small-scale orange juice industries: A Colombian case study

Appropriate waste management in emerging economies like Colombia should be an asset for the overall sustainability. In the Orange Peel Waste case, incineration and Anaerobic Digestion are challenging solutions for the orange juice agro-industrial sector for avoiding the landfill, which is the conventional practice. However, these alternatives should be assessed in order to determine their feasibility. This paper aims to understand if incineration and Anaerobic Digestion are potential alternatives to landfill form a techno-economic and environmentally perspective. To this aim, a comparative Life Cycle Assessment was carried out in four scenarios. In the first scenario coal and landfill are used as source of energy and landfill disposal in the actual orange juice process. In the second scenario, the peels are incinerated to avoid landfill and reduce the need for coal. The third scenario includes the valorization of the peels by means of Anaerobic Digestion which produces biogas for the plant energy requirements. In the fourth scenario, apart from the energy from biogas, the digestate becomes a fertilizer for use in the orange crops. The results revealed that scenario III and IV are environmentally friendly options compared to Scenario I, but they incur higher costs than Scenario II. Carbon footprint found that 1.55 kg of CO2 are saving when coal substitution is reduced from 0.493 kg in SI to 0.279 kg in SII. Therefore, Scenario II is more suitable for the Colombian socioeconomic reality since Scenario II is not only techno-environmentally achievable, but also economically feasible. The methodology used in this case study could be applied to other countries or small and medium scale technologies and could also be useful for the scientific community, enterprises and policy-makers.The authors wish to acknowledge the financial support of the Fondo Regional de Tecnología Agropecuaria FONTAGRO [Contract:ATN/RF 16111RG, 2016] and of the Departamento Administrativo de Ciencia, Tecnología e Innovación, Doctorados Nacionales [Contract:727, 2015]. Also this article is the result of the work developed through the "Programa de investigación reconstrucción del tejido social en zonas de pos-conflicto en Colombia" [SIGP 57579] withthe research project "Competencias empresariales y de innovación para el desarrollo económico y la inclusión productiva de las regiones afectadas por el conflicto colombiano" [SIGP 58907]. Finally, the authors would like to express their appreciation to FLP Procesados Company for providing the data for the case study

Incisivo lateral superior con dos raíces y dos conductos. Caso Clínico.

Las anomalías en la morfología del incisivo lateral superior son de muy baja frecuencia. Las anomalías de desarrollo radicular pueden presentarse como alteraciones tanto en el número de conductos, como en el número de raíces, así como en ambas regiones a la vez. En el presente trabajo, se reporta el caso de un paciente que se presenta a la consulta con malestar en el incisivo lateral superior izquierdo. En la radiografía preoperatoria se detectó la presencia de dos conductos y dos raíces, sin anomalía morfológica de su corona clínica, con requerimiento de tratamiento endodóntico. Concluimos que una correcta interpretación de las imágenes radiográficas preoperatorias es esencial, para poder detectar estas variantes y tomar las consideraciones necesarias para el adecuado tratamiento endodóntico.Fil: Martinez, P.. Universidad de Buenos Aires. Facultad de Odontología; Argentina;Fil: Boldo, M.. Universidad de Buenos Aires. Facultad de Odontología; Argentina;Fil: Corominola, P.. Universidad de Buenos Aires. Facultad de Odontología; Argentina;Fil: Sierra, L.. Universidad de Buenos Aires. Facultad de Odontología; Argentina;Fil: Lenarduzzi, A.. Universidad de Buenos Aires. Facultad de Odontología; Argentina;Fil: Fernández Solari, Jose Javier. Universidad de Buenos Aires. Facultad de Odontología. Cátedra de Fisiología; Argentina;Fil: Rodriguez, P.. Universidad de Buenos Aires. Facultad de Odontología; Argentina

Dynamic mechanical behavior of starch-based scaffolds in dry and physiologically simulated conditions: effect of porosity and pore size

The three-dimensional scaffolds of a blend of starch and poly(L-lactic) acid, SPLA70, were produced using compression molding of polymer/salt mixture followed by leaching of salt. One series of scaffolds were prepared with varying polymer-to-salt ratio while keeping the salt size constant, and the other series of scaffolds were prepared with varying salt sizes while keeping the polymer-to-salt ratio constant. The X-ray microcomputed tomography and scanning electron microscopy assay were used to analyze the porous morphologies, porosity and distribution of porosity of the porous scaffolds. Salt-free and integrated SPLA70 scaffolds with porosities ranging from 74% to 82% and pore sizes of 125–250 to 500–1000 lm can be fabricated using the present fabrication technique. The water uptake of the SPLA70 scaffolds increases with increasing porosities and also with increasing pore size. In dry state, the storage modulus decreases with increasing porosity and also with increasing pore size. The normalized modulus values are related to normalized density of the scaffolds by a power-law function with an exponent between 2 and 3. For the immersed scaffolds under physiological conditions, the storage modulus was less dependent on porosity and pore size. However, the loss factor increased significantly compared with dry state measurements. The present study clearly shows that the mechanical performance of porous polymeric constructs in dry and in immersed state is completely different, and for comparison with biomechanical performance of tissues, the tests should ideally be performed in immersed state

Beyond conventional factorization: Non-Hermitian Hamiltonians with radial oscillator spectrum

The eigenvalue problem of the spherically symmetric oscillator Hamiltonian is revisited in the context of canonical raising and lowering operators. The Hamiltonian is then factorized in terms of two not mutually adjoint factorizing operators which, in turn, give rise to a non-Hermitian radial Hamiltonian. The set of eigenvalues of this new Hamiltonian is exactly the same as the energy spectrum of the radial oscillator and the new square-integrable eigenfunctions are complex Darboux-deformations of the associated Laguerre polynomials.Comment: 13 pages, 7 figure

Prototyping of petalets for the Phase-II Upgrade of the silicon strip tracking detector of the ATLAS Experiment

In the high luminosity era of the Large Hadron Collider, the HL-LHC, the instantaneous luminosity is expected to reach unprecedented values, resulting in about 200 proton-proton interactions in a typical bunch crossing. To cope with the resultant increase in occupancy, bandwidth and radiation damage, the ATLAS Inner Detector will be replaced by an all-silicon system, the Inner Tracker (ITk). The ITk consists of a silicon pixel and a strip detector and exploits the concept of modularity. Prototyping and testing of various strip detector components has been carried out. This paper presents the developments and results obtained with reduced-size structures equivalent to those foreseen to be used in the forward region of the silicon strip detector. Referred to as petalets, these structures are built around a composite sandwich with embedded cooling pipes and electrical tapes for routing the signals and power. Detector modules built using electronic flex boards and silicon strip sensors are glued on both the front and back side surfaces of the carbon structure. Details are given on the assembly, testing and evaluation of several petalets. Measurement results of both mechanical and electrical quantities are shown. Moreover, an outlook is given for improved prototyping plans for large structures.Comment: 22 pages for submission for Journal of Instrumentatio

High-temperature magnetodielectric Bi(Fe0.5Mn0.5)O3 thin films with checkerboard-ordered oxygen vacancies and low magnetic damping

The possibility of affecting the magnetic properties of a material by dielectric means, and vice versa, remains an attractive perspective for modern electronics and spintronics. Here, we report on epitaxial Bi(Fe0.5Mn0.5)O3 thin films with exceptionally low Gilbert damping and magnetoelectric coupling above room temperature (<400 K). The ferromagnetic order, not observed in bulk, has been detected with a total magnetization of 0.44 μB/formula units with low Gilbert damping parameter (0.0034), both at room temperature. Additionally, a previously overlooked check-board ordering of oxygen vacancies is observed, providing insights on the magnetic and dielectric origin of the multifunctional properties of the films. Finally, intrinsic magnetodielectric behavior is observed as revealed by the variation of dielectric permittivity well above room temperature. These findings show the possibility of electric-field-controlled magnetic properties, in low Gilbert-damping-based spintronic devices, using single-phase multiferroic material

Coupling the dynamics and the molecular chemistry in the Galactic center

The physical conditions of the Galactic center (GC) clouds moving with non-circular velocities are not well-known. We have studied the physical conditions of these clouds with the aim of better understanding the origin of the outstanding physical conditions of the GC molecular gas and the possible effect of the large scale dynamics on these physical conditions.Using published CO(1-0) data, we have selected a set of clouds belonging to all the kinematical components seen in the longitude-velocity diagram of the GC. We have done a survey of dense gas in all the components using the J=2-1 lines of CS and SiO as tracers of high density gas and shock chemistry. We have detected CS and SiO emission in all the kinematical components. The gas density and the SiO abundance of the clouds in non-circular orbits are similar those in the nuclear ring (GCR). Therefore, in all the kinematical components there are dense clouds that can withstand the tidal shear. However, there is no evidence of star formation outside the GCR. The high relative velocity and shear expected in the dust-lanes along the bar major axis could inhibit the star formation process, as observed in other galaxies. The high SiO abundances derived in the non-circular velocity clouds are likely due to the large-scale shocks that created the dust lanesComment: One figure as an independent PDF file. Accepted by A&