Risk Assessment Due to Debris Flows in Paz de Río-Colombia

Paz de Río is an important economic area of Colombia where iron mines produce most of the mineral for the steel production in the country. Along the La Chapa creek some debris flows have occurred since 1963 producing economic losses and human deaths at Santa Teresa village. Economical losses are related to disruption of the main access to La Chapa iron mine facilities, and flooding of Paz de Río due to damming of Chicamocha River, the main drainage system of the region, which is blocked by debris flows. The local authority for Natural Disaster Management (CREPAD) jointly with the Universidad Nacional de Colombia carries out the risk evaluation related to potential debris flows along the creek. The study models the debris flow using the FLO2D software considering the geological, geomorphologic, topographic and hydrological setting of the area. As main sediment source we considered the potential volume of material supplied by a large landslide at the upper part of the creek basin, known locally as the Mesa Alta landslide, whereas sediment production due to landslides within the basin was considered as point inflows along the creek. Physical vulnerability was evaluated by using the Leone (1999) approach, which considers the flow height and its relation with the structure height, whereas social vulnerability was evaluated by considering factors as population density, people age, literacy level and economical income. Risk assessment was based on the Liu and Lei (2003) approach in which risk is defined graphically considering critical threshold curves obtained from vulnerability and hazard values. Risk for different elements within the influence area of the creek was evaluated and mitigation measures including engineering works were proposed, the influence of these measures on hazard and risk was also evaluated

What are we learning about speciation and extinction from the Canary Islands?

Oceanic islands are excellent systems for allowing biologists to test evolutionary hypotheses due to their relative simplicity of habitats, naturally replicated study design and high levels of endemic taxa with conspicuous variation in form, colour and behaviour. Over the last two decades the Canary Islands archipelago has proved an ideal system for evolutionary biologists who seek to unravel how biodiversity arises and disappears. In this review we have evaluated the contribution of the study of Canarian birds to our understanding of how and why species occur and change over time. We focus our attention on both extant and extinct Canarian taxa, and describe how research on these species has filled gaps in our understanding of avian speciation and extinction. In addition, we discuss the necessity of revising the current taxonomy in the Canarian avian taxa, especially the status of the endemic subspecies, some of which might be better treated as full species. An accurate classification of Canarian birds is not only necessary for testing evolutionary, biogeographic and ecological hypotheses, but also for effective decision making about conservation and environmental management. Finally we introduce future avenues of research that we feel will yield the most exciting and promising findings on island evolution in the coming years. Las islas oceánicas son sistemas ideales para abordar hipótesis evolutivas debido a la relativa simplicidad de sus hábitats, el adecuado número de entidades discretas donde replicar los resultados, y las elevadas tasas de taxones endémicos con variaciones significativas en formas, colores y comportamientos. Durante las dos últimas décadas el archipiélago canario ha sido el escenario perfecto para los biólogos evolutivos en donde entender cómo surge y desaparece la biodiversidad. En el presente artículo hemos evaluado la contribución de las aves canarias para responder a las preguntas de cómo y por qué las especies están presentes, persisten y cambian con el tiempo. Centraremos nuestra atención tanto en especies actuales y extintas, y describiremos cómo las investigaciones desarrolladas en los últimos años han facilitado nuestra compresión sobre los procesos de especiación y extinción. Además, discutiremos la necesidad de revisar la taxonomía actual de los taxones canarios, siendo ello especialmente necesario a nivel de subespecies, ya que algunas de ellas serían merecedoras de ser consideradas especies verdaderas. Una clasificación correcta de las aves canarias no sería solo determinante para abordar hipótesis evolutivas, biogeográficas y ecológicas, sino también para tomar decisiones efectivas de conservación y manejo sostenible de los taxones afectados. Finalmente, terminaremos introduciendo las líneas de investigación donde creemos que en un futuro próximo proporcionarán los hallazgos más prometedores y estimulantes sobre evolución en medios insulares

Acculturation is associated with left ventricular mass in a multiethnic sample: the Multi-Ethnic Study of Atherosclerosis.

BackgroundAcculturation involves stress-related processes and health behavioral changes, which may have an effect on left ventricular (LV) mass, a risk factor for cardiovascular disease (CVD). We examined the relationship between acculturation and LV mass in a multiethnic cohort of White, African-American, Hispanic and Chinese subjects.MethodsCardiac magnetic resonance assessment was available for 5004 men and women, free of clinical CVD at baseline. Left ventricular mass index was evaluated as LV mass indexed by body surface area. Acculturation was characterized based on language spoken at home, place of birth and length of stay in the United States (U.S.), and a summary acculturation score ranging from 0 = least acculturated to 5 = most acculturated. Mean LV mass index adjusted for traditional CVD risk factors was compared across acculturation levels.ResultsUnadjusted mean LV mass index was 78.0 ± 16.3 g/m(2). In adjusted analyses, speaking exclusively English at home compared to non-English language was associated with higher LV mass index (81.3 ± 0.4 g/m(2) vs 79.9 ± 0.5 g/m(2), p = 0.02). Among foreign-born participants, having lived in the U.S. for ≥ 20 years compared to < 10 years was associated with greater LV mass index (81.6 ± 0.7 g/m(2) vs 79.5 ± 1.1 g/m(2), p = 0.02). Compared to those with the lowest acculturation score, those with the highest score had greater LV mass index (78.9 ± 1.1 g/m(2) vs 81.1 ± 0.4 g/m(2), p = 0.002). There was heterogeneity in which measure of acculturation was associated with LV mass index across ethnic groups.ConclusionsGreater acculturation is associated with increased LV mass index in this multiethnic cohort. Acculturation may involve stress-related processes as well as behavioral changes with a negative effect on cardiovascular health

A Study of the Formal Architectural-Sculptural Characteristics of El Tajin

El Tajín was an ancient metropolis in which rituals such as the Mesoamerican ball game were carried out, later to be recorded in the sculptural bas-reliefs of its architecture. The study of its morphologies is the recognition of the ways in which an ancient civilization is expressed, thus contributing to the characterization of a culture whose past belongs to World Heritage. This paper proposes a case-sample analysis of the bas-reliefs in the South Ballcourt based on reticular geometry and fractal dimension analysis. It was found that the geometry of the RA (golden rectangle), RR2 and RR3 are prevalent, in addition to the identification of iconographic naturalist and symbolic elements; from the box-counting fractal dimension, it was found that the elements, though of different sizes or composition, show similar complexities, with a value of around 1.7

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870). Epidemiological studies have shown a correlation between the presence of the G870A allele (that favors the splicing for cyclin D1b) with increased risk and less favorable outcome in several forms of cancer. More recently, it has been shown that, unlike cyclin D1a, the alternative transcript D1b by itself has the capacity to transform fibroblasts in vitro. In order to study the oncogenic potential of cyclin D1b, we developed transgenic mice expressing human cyclin D1b under the control of the bovine K5 promoter (K5D1b mice). Seven founders were obtained and none of them presented any significant phenotype or developed spontaneous tumors. Interestingly, K5D1b mice do not develop the fatal thymic hyperplasia, which is characteristic of the cyclin D1a transgenic mice (K5D1a). Susceptibility to skin carcinogenesis was tested in K5D1b mice using two-stage carcinogenesis protocols. In two independent experiments, K5D1b mice developed higher papilloma multiplicity as compared with wild-type littermates. However, when K5D1b mice were crossed with cyclin D1KO mice, the expression of cyclin D1b was unable to rescue the carcinogenesis-resistant phenotype of the cyclin D1 KO mice. To further explore the role of cyclin D1b in mouse models of carcinogenesis we carried out in silico analysis and in vitro experiments to evaluate the existence of a mouse homologous of the human cyclin D1b transcript. We were unable to find any evidence of an alternatively spliced transcript in mouse Ccnd1. These results show that human cyclin D1b has different biological functions than cyclin D1a and confirm its oncogenic properties.Fil: Rojas, Paola Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. University of Texas; Estados UnidosFil: Benavides, Fernando. University of Texas; Estados UnidosFil: Blando, Jorge. University of Texas; Estados UnidosFil: Pérez, Carlos. University of Texas; Estados UnidosFil: Cardenas, Kim. University of Texas; Estados UnidosFil: Richie, Ellen. University of Texas; Estados UnidosFil: Knudsen, Erik S.. Thomas Jefferson University; Estados UnidosFil: Johnson, David G.. University of Texas; Estados UnidosFil: Senderowicz, Adrian M.. Department of Health and Human Services. Food and Drug Administration. Center for Drug Evaluation and Research; Estados UnidosFil: Rodriguez Puebla, Marcelo L.. University of North Carolina; Estados UnidosFil: Conti, Claudio. University of Texas; Estados Unido

Perímetros de protección de pozos: marco legal para su implementación en Argentina

Con el propósito de proteger las fuentes de suministro de agua, se pueden establecer una serie de zo nas, generalmente concéntricas, en torno al/los pozo/s (perímetros de protección), sobre la base del conocimiento hidrogeológico. En estas zonas será necesario establecer niveles de control diferenciales para el uso del territorio en función de las condiciones y necesidades locales. En este trabajo se analizan los instrumentos jurídicos, en el marco del plexo normativo argentino, necesarios para llevar adelante una efectiva protección, en especial, la potestad de los gobiernos locales para establecer las estrategias útiles.In order to protect water sources, different areas, generally concentric around well could be define on the basis of hydrogeological knowledge. In these areas will be necessary to establish differential control levels for land use based on local needs and conditions. Legal instruments necessary to carry out this effective protection are analyzed here. Particularly, it is considered the local government power to establish useful strategies.Universidad Nacional de La Plat

Z_4 flavor model in Randall-Sundrum model 1

Randall Sundrum models provide a possible explanation of (gauge-gravity) hierarchy, whereas discrete symmetry flavor groups yield a possible description of the texture of Standard Model fermion masses. We use both these ingredients to propose a five-dimensional extension of the Standard Model where the mass hierarchy of the four-dimensional effective field theory is obtained only using localizations parameters of order 1. We consider a bulk custodial gauge symmetry group together with an Abelian $Z_4$ group: the model turns out to yield a rather minimal extension of the SM as it only requires two brane Higgs fields to provide the desired Yukawa interactions and the required spontaneous symmetry breaking pattern. In fact, the presence of an extra-dimension allows the use of the Scherk-Schwarz mechanism to contribute to the breaking of the bulk custodial group down to the SM gauge symmetry. Moreover, no right-handed neutrinos are present and neutrino masses are generated radiatively with the help of a bulk charged scalar field that provides the Lepton-number violation. Using experimental inputs from the Global Neutrino Analysis and recent Daya Bay results, a numerical analysis is performed and allowed parameter regions are displayed.Comment: 23 pages, 3 figures. A brief discussion on contribution from higher order operators has been added, a few typos corrected and references added. Version to appear in Phys. Rev.

3D Gravity Modeling of Complex Salt Features in the Southern Gulf of Mexico

We present a three-dimensional (3D) gravity modeling and inversion approach and its application to complex geological settings characterized by several allochthonous salt bodies embedded in terrigenous sediments. Synthetic gravity data were computed for 3D forward modeling of salt bodies interpreted from Prestack Depth Migration (PSDM) seismic images. Density contrasts for the salt bodies surrounded by sedimentary units are derived from density-compaction curves for the northern Gulf of Mexico’s oil exploration surveys. By integrating results from different shape- and depth-source estimation algorithms, we built an initial model for the gravity anomaly inversion. We then applied a numerically optimized 3D simulated annealing gravity inversion method. The inverted 3D density model successfully retrieves the synthetic salt body ensemble. Results highlight the significance of integrating high-resolution potential field data for salt and subsalt imaging in oil exploration