Corporate Structure that Supports and Facilitates Social Good

Over the past few years the pedagogical philosophy of the Molloy College Graduate Program has been demonstrated through a series of publications, which have provided evidence of learning at both the course and program level. The foundational pedagogical philosophy is that business graduate students should demonstrate learning by doing. Therefore every MBA graduate must demonstrate that he or she can draw from the knowledge, skills, and disposition developed within the graduate program and be able to publicly demonstrate that the learning can be applied in the real-world. The mission of the institution establishes the founding belief in social responsibility, service, community, and study. The college’s commitment to academic excellence and the promotion of lifelong learning demonstrates the transformative education experienced by the students. As a result, the evidence of learning for the MBA program is a set of solution-driven recommendations that will lead to social good

Educators Must Be Advocates: Advocating for Muslim Students

As educators interested in supporting linguistically and culturally diverse learners, we have had to view our roles in different ways since the presidential campaign and the election of Trump. In this article, two teacher educators and two inservice ESL teachers in the U.S. reflect on our various experiences working with Muslim students and preparing teachers to support Muslim students in the current socio-political context. We discuss these experiences with the goal of suggesting some priorities in teacher education. Ultimately, to prepare teachers to be effective teachers for Muslim students requires them to go beyond being culturally responsive to becoming advocates and activists. This advocacy and activism necessitates a push against the cultural norms of Whiteness that dominate U.S. teacher education

Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives

Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen. This explains the increasing interest showed by many groups of research and pharmaceutical companies to find compounds with potential to disrupt at least one of the steps within the angiogenic process. Hydroxytyrosol (3,4-dihydroxyphenyl ethanol) has been identified as the most important health-related phenolic compound of virgin olive oil because of its pleiotropic effects on multiple targets. In 2012, our group identified hydroxytyrosol as an anti-angiogenic compound able to inhibit several key steps in the angiogenic process. In the present study, the potential effects of six hydroxytyrosol derivatives are tested and compared with those exhibited by hydroxytyrosol by making use of several in vitro and in vivo assays. Results indicate that these are candidate new anti-angiogenic compounds with potential utility in anti-tumor and anti-angiogenic therapies.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech [Our experimental work is supported by grants BIO2014-56092-R (MINECO and FEDER) and P12-CTS-1507 (Andalusian Government and FEDER) and funds from group BIO-267 (Andalusian Government). The "CIBER de Enfermedades Raras" is an initiative from the ISCIII (Spain)]. This communication has the support of a travel grant

Benthic organic carbon release stimulates bacterioplankton production in a clear-water subarctic lake

We carried out a set of experiments in a small clear-water lake in northern Sweden during summer 2010 to assess the effect of organic C (OC) released from epipelic algae on pelagic bacterial production (BP). The release rate of OC (dissolved and particulate) from epipelic algae was ,45.4 ng C m22 h21 . Bacterioplankton uptake of dissolved OC was P-limited, and pelagic primary production (PP) was colimited by N and P. Pelagic BP (3.2 6 6 mgCL21 h21 ) exceeded pelagic PP (0.012 6 0.008 mg C L21 h21 ). Pelagic BP was higher in lake water in contact with sediments and the epipelic algae growing on their surface than in water separated from the sediments. Epipelic algae release OC to lake water and potentially stimulate pelagic BP. However, exploitation of benthic OC probably is suboptimal because of nutrient limitation (primarily by inorganic P) of BP.Fil: Rodriguez, Patricia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina; Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina;Fil: Ask, Jenny. Umea University. Department of Ecology and Environmental Science; Suecia;Fil: Hein, Catherine L.. Umea University. Department of Ecology and Environmental Science. Climate Impacts Research Center; Suecia;Fil: Jansson, Mats. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina;Fil: Karlsson, Jan. Umea University. Department of Ecology and Environmental Science. Climate Impacts Research Center; Suecia

APPRIS principal isoforms and MANE Select transcripts define reference splice variants.

Selecting the splice variant that best represents a coding gene is a crucial first step in many experimental analyses, and vital for mapping clinically relevant variants. This study compares the longest isoforms, MANE Select transcripts, APPRIS principal isoforms, and expression data, and aims to determine which method is best for selecting biological important reference splice variants for large-scale analyses. Proteomics analyses and human genetic variation data suggest that most coding genes have a single main protein isoform. We show that APPRIS principal isoforms and MANE Select transcripts best describe these main cellular isoforms, and find that using the longest splice variant as the representative is a poor strategy. Exons unique to the longest splice isoforms are not under selective pressure, and so are unlikely to be functionally relevant. Expression data are also a poor means of selecting the main splice variant. APPRIS principal and MANE Select exons are under purifying selection, while exons specific to alternative transcripts are not. There are MANE and APPRIS representatives for almost 95% of genes, and where they agree they are particularly effective, coinciding with the main proteomics isoform for over 98.2% of genes. APPRIS principal isoforms for human, mouse and other model species can be downloaded from the APPRIS database (https://appris.bioinfo.cnio.es), GENCODE genes (https://www.gencodegenes.org/) and the Ensembl website (https://www.ensembl.org). MANE Select transcripts for the human reference set are available from the Ensembl, GENCODE and RefSeq databases (https://www.ncbi.nlm.nih.gov/refseq/). Lists of splice variants where MANE and APPRIS coincide are available from the APPRIS database. Supplementary data are available at Bioinformatics online.This paper was published as part of a special issue financially supported by ECCB2022. This work was supported by the National Human Genome Research Institute of the National Institutes of Health under Award Number U24HG007234. This work was also supported by the following grants: PGC2018-097019-B-I00/Ministry of Science, Innovation and Universities; IPT17/0019/Carlos III Institute of Health-Fondo de Investigacio´n Sanitaria and HR17-00247/‘la Caixa’ Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.S

Dicamba residue persistence in processing tomato

There is zero tolerance for dicamba and dicamba metabolite residue in tomato (Solanum lycopersicum L.) fruit following exposure to dicamba. Field trials were conducted in 2020 and 2021 to determine the persistence of dicamba and metabolite (5-hydroxy dicamba and 3,6-dichlorosalicylic acid [DCSA]) residue in processing tomato shoots and fruits. Dicamba was applied 49 d after transplanting at 0, 0.53, 5.3, and 53 g ae ha−1. Tomato plants were harvested 5, 10, 20, 40, and 61 d after treatment (DAT). No 5-hydroxy dicamba was recovered from any sample. In 2020, the DCSA metabolite was detected from tomato shoot tissue when dicamba was applied at the 53 g ha−1 rate at 0 (14 µg kg−1), 5 (3 µg kg−1), and 20 DAT (5 µg kg−1) and from tomato fruit tissue at 53 g ha−1 at 20 (2 µg kg−1) and 61 DAT (2 µg kg−1). In 2021, DCSA was not detected from tomato shoot or fruit tissues at any harvest date. By 5 DAT, dicamba was only detected from tomato shoot tissues treated with 53 g ha−1. At 0 DAT, dicamba residue was detectable only from tomato fruit on plants treated with 53 g ha−1. Tomato fruit dicamba residue from plants treated with 5.3 g ha−1 had a predicted peak of 19 µg kg−1 at 11.3 DAT. Tomato fruit dicamba residue from plants treated with 53 g ha−1 decreased from 164 to 8 µg kg−1 from 5 to 61 DAT. Furthermore, this study confirms that dicamba is detectable from tomato fruits at 61 DAT following exposure to 5.3 or 53 g ha−1 dicamba. Growers who suspect dicamba exposure should include tomato fruit tissue with their collected sample or sample tomato fruits separately

Apples and Oranges: Comparing the Backgrounds and Academic Trajectories of International Baccalaureate (IB) Students to a Matched Comparison Group

This report presents findings from a retrospective study of the academic histories of International Baccalaureate (IB) students and other students in the state of Florida. The IB Diploma Program is an internationally recognized college-preparatory curriculum designed to provide students with a rigorous and comprehensive academic experience. IB has grown dramatically in recent years and is thought by many to be among the best college-preparatory programs in existence. As such, there is tremendous interest in the potential impacts of IB, but any attempts to examine those impacts must deal with selection bias that results from the voluntary participation of schools and students. Failure to do so makes it impossible to determine whether the performance of participating students was actually influenced by IB, or whether the outcomes for these students would have been just as good without IB. As a critical step in understanding the impacts of IB, the analyses presented in this report examined the selection mechanisms behind IB participation across Florida, the state with the second highest representation of IB programs in the nation. We use longitudinal student and school-level data from 1995 through 2009 from the Florida K-20 Education Data Warehouse (EDW) to characterize individual students’ educational histories from elementary school through high school and into college. To address issues of selection bias, we use propensity score methods (Rosenbaum & Rubin, 1983) to adjust for preexisting differences between IB and non-IB students

Resolved Debris Discs Around A Stars in the Herschel DEBRIS Survey

The majority of debris discs discovered so far have only been detected through infrared excess emission above stellar photospheres. While disc properties can be inferred from unresolved photometry alone under various assumptions for the physical properties of dust grains, there is a degeneracy between disc radius and dust temperature that depends on the grain size distribution and optical properties. By resolving the disc we can measure the actual location of the dust. The launch of Herschel, with an angular resolution superior to previous far-infrared telescopes, allows us to spatially resolve more discs and locate the dust directly. Here we present the nine resolved discs around A stars between 20 and 40 pc observed by the DEBRIS survey. We use these data to investigate the disc radii by fitting narrow ring models to images at 70, 100 and 160 {\mu}m and by fitting blackbodies to full spectral energy distributions. We do this with the aim of finding an improved way of estimating disc radii for unresolved systems. The ratio between the resolved and blackbody radii varies between 1 and 2.5. This ratio is inversely correlated with luminosity and any remaining discrepancies are most likely explained by differences to the minimum size of grain in the size distribution or differences in composition. We find that three of the systems are well fit by a narrow ring, two systems are borderline cases and the other four likely require wider or multiple rings to fully explain the observations, reflecting the diversity of planetary systems.Comment: 19 pages, 13 figures, 6 tables. Accepted for publication in MNRA