Acordos de livre comércio do Mercosul : cenário de conflito de interesses entre Brasil e Argentina

Trabalho de Conclusão de Curso (graduação)—Universidade de Brasília, Faculdade de Economia, Administração e Contabilidade, Departamento de Economia, 2020.Este trabalho tem o objetivo de analisar o cenário de acordos comerciais do MERCOSUL envolvendo conflitos de interesses entre Brasil e Argentina. Para entender os efeitos desses conflitos entre ambos nos acordos, são analisados os impactos sobre as variações de bem-estar, Produto Interno Bruto, variações no valor adicionado para cada setor, assim como variação percentual de bens exportados e importados e variação da utilidade per capita. Para realizar esta análise, foi utilizado o modelo de equilíbrio geral computável, conhecido como GTAP (Global Trade Analysis Project), aplicado no software RunGTAP. Além disso, foram simulados dois cenários para comparação, sendo um com a União Europeia e outro com os EUA. O primeiro foi utilizado devido ao atual progresso do acordo, muito próximo de ser consolidado e por estar sendo negociado por muito tempo, enquanto o segundo é um dos principais parceiros do MERCOSUL nos acordos comerciais e uma das principais potências econômicas do mundo. Os resultados apurados indicam conformidade dos acordos com as teorias econômicas de comércio internacional, assim como melhorias em níveis de bem estar em sua maioria e alinhamento das vantagens comparativas das regiões. Para o Brasil, o acordo com a União Europeia é preferível, tendo em vista que possui variação positiva tanto para os níveis de bem-estar quanto no Produto Interno Bruto, assim como uma maior eficiência alocativa. Para a Argentina, ocorrem poucos incrementos nos níveis de bem-estar para ambos os cenários, assim como o PIB teve queda em ambos e queda do valor agregado em boa parte dos setores, com indícios de resistência no fechamento de acordos de livre comércio dentro do MERCOSUL. Devido a isso, há dificuldades em fechar novos acordos de livre comércio pelo MERCOSUL com este cenário de conflitos de interesses entre Brasil e Argentina.This paper aims to analyse the outlook of free trade agreements of MERCOSUR envolving conflict of interests between Brazil and Argentina. To understand the effects about conflict between the both, are analysed the impacts on the welfare variation, gross domestic product, value added variation for each sector, as well as goods exported and imported percentual variation and per capita utility variation . For this analysis, the computable general equilibrium was applied, known as GTAP (Global Trade Analysis Project). Two outlooks were simulated, European Union and USA. The first is required because of actual progress agreement is being consolidated and was being dealed for many years, while the second is one of principal partners of MERCOSUR in trade agreements. The results appointed according to economics theories of international trade, as well as growth about welfare in majority and alignment about comparative advantages. For Brazil, the agreement to European Union is better, remembering that Brazil has high levels in welfare, gross domestic product and allocation efficient. For Argentina, the low increments were added in welfare on both outlooks, as well as the gross domestic product decreased on both outlooks, appointing evidences to possible resistance of conclusion about free trade agreements in MERCOSUR. Given that, there are difficulties in close new free trade agreements for MERCOSUR with this conflict of interests between Brazil and Argentina

Impaired NK cell cytotoxicity in multiple myeloma caused by the homozygous A91V polymorphism in the perforin gene: a case report: Citotoxicidade de células NK prejudicada no mieloma múltiplo causada pelo polimorfismo A91V em homozigose no gene da perforina: um relato de caso

We describe a 58-year-old man diagnosed with IgG/Kappa multiple myeloma (International Staging System III) treated for eight years with polychemotherapy (VAD schee) and autologous peripheral hematopoietic stem cell transplantation. The patient studied was homozygous C272T polymorphism (PRF1272T/T) by analysis of perforin gene by direct sequencing. This SNP is considered pathogenic and leads to the substitution of the amino acid alanine for valine in codon 91 of the perforin protein. The cytotoxic lymphocytes (CLs) of the patient and of the healthy wild homozygous individual were evaluated for their cytotoxic capacity. Our results show that PRF1272T/T effector cells had significantly reduced ability to induce specific lysis of K562 cells. The NK cells of the patient had three times less intracellular perforin than observed in the wild-type individual. The gene expression of PRF1 and FAS did not differ between the individuals, however the expression of GZMB was approximately 2.5 times higher in the patient. It was also observed that the T-BET expression was approximately 1.7-fold higher and IFN-γ expression was 4.5-fold higher in the PRF1272T/T patient. In conclusion, functional analysis of the CLs of the patient revealed a significant decrease in their cytolytic capacity as well as the amount of perforin present in NK cell granules

Impaired NK cell cytotoxicity in multiple myeloma caused by the homozygous A91V polymorphism in the perforin gene: a case report: Citotoxicidade de células NK prejudicada no mieloma múltiplo causada pelo polimorfismo A91V em homozigose no gene da perforina: um relato de caso

We describe a 58-year-old man diagnosed with IgG/Kappa multiple myeloma (International Staging System III) treated for eight years with polychemotherapy (VAD schee) and autologous peripheral hematopoietic stem cell transplantation. The patient studied was homozygous C272T polymorphism (PRF1272T/T) by analysis of perforin gene by direct sequencing. This SNP is considered pathogenic and leads to the substitution of the amino acid alanine for valine in codon 91 of the perforin protein. The cytotoxic lymphocytes (CLs) of the patient and of the healthy wild homozygous individual were evaluated for their cytotoxic capacity. Our results show that PRF1272T/T effector cells had significantly reduced ability to induce specific lysis of K562 cells. The NK cells of the patient had three times less intracellular perforin than observed in the wild-type individual. The gene expression of PRF1 and FAS did not differ between the individuals, however the expression of GZMB was approximately 2.5 times higher in the patient. It was also observed that the T-BET expression was approximately 1.7-fold higher and IFN-γ expression was 4.5-fold higher in the PRF1272T/T patient. In conclusion, functional analysis of the CLs of the patient revealed a significant decrease in their cytolytic capacity as well as the amount of perforin present in NK cell granules

VIOLÊNCIA POLÍTICA CONTRA AS MULHERES: OS MOVIMENTOS SOCIAIS NAS DINÂMICAS DE ELABORAÇÃO DOS PROJETOS DE LEI

Violence against women in politics is perceived as one of the obstacles to the participation of women in politics in conditions of equality with men. In this sense, this research proposes to analyze the participation of social collectives in the dynamics of drafting bills related to combating political violence against women, using Bill 349/2015 as a starting point. The results point to the importance of social collectives in dialogical constructions and the advancement of important themes for society.  La violencia contra las mujeres en la política se percibe como uno de los obstáculos para la participación de las mujeres en la política en igualdad de condiciones con los hombres. En este sentido, la presente investigación se propone analizar la participación de los colectivos sociales en la dinámica de elaboración de los proyectos de ley relacionados con la lucha contra la violencia política hacia las mujeres, tomando como punto de partida el Proyecto de Ley 349/2015. Los resultados apuntan a la importancia de los colectivos sociales en la construcción dialógica y el avance de temas importantes para la sociedad.    A violência contra as mulheres na política é percebida como um dos obstáculos para a participação das mulheres na política em condições de igualdade com os homens. Neste sentido, a presente pesquisa se propõe a analisar a participação dos coletivos sociais nas dinâmicas de elaboração de Projetos de Lei relacionados ao combate da violência política contra as mulheres, utilizando como ponto de partida o Projeto de Lei 349/2015. Os resultados apontam para a importância dos coletivos sociais em construções dialógicas e avanço de temas importantes para a sociedade. &nbsp

Physiological analysis and nutritional quality of maize: a comparative study between hybrid and landraces varieties

Maize (Zea mays L.) is important for animal production systems, and the use of unimproved maize varieties has increasinglybecome a viable option for small farmers. This study aimed to characterize and evaluate the physiologicaland feed potential of maize populations, as a raw material for silage production, in the mesoregion of the AltoParanaiba, Minas Gerais (MG). We used nine varieties of unimproved maize from the Germplasm Bank at EmbrapaMaize & Sorghum - BAGMilho (Sete Lagoas, MG), as follows: (milho stands for maize; crioulo, for landrace) MG110 – Milho Amarelão, MS 043 – Crioulo, MG 083 – Milho Branco, RN 013 – Milho Metro, MG 073 – Milho Vermelhinho,MS 016 – Palha Roxa 90, MG 079 – Milho Cunha, RR 040 – Crioulo de Roraima, AC 015 – Milho Bolivianoand a commercial hybrid variety of Pioneer, P4285. The hybrid maize Pioneer P4285 showed better physiologicaland nutritional performance. Among the accessions of the Germplasm Bank, the MG 110 – Milho Amarelão andMG 015 – Milho Boliviano were distinguished by their physiological adaptation to the Cerrado of Minas Gerais,and for showing characteristics suitable for use in the silage process for animal feed

Breastfeeding during adolescence: life history of first-time mothers

Objective: To identify the factors that influence on primiparous adolescent mothers' breastfeeding and to comprehend the meaning of it to this woman. Method: This is a descriptive, of qualitative nature research. The subjects were 14 primiparous adolescent mothers, invited to participate in the research during the puericulture consulting in a Basic Health Care Unit, in Rio de Janeiro. The data were collected using a recorder with application of Life History technique and analyzed with thematic-categorical content. The study was approved by the Ethics and Research Committee of HUPE/UERJ under the Nº1116/2005. Results: The youngsters revealed the existence of several factors those influence the meaning they attach to breastfeeding as the biological, psychological, social, economic and family aspects, contributing to the construction of a multiplicity of meanings. Conclusion: The adolescent mother, when conceive her first baby experiences the emotion and felling associated with maternity and breastfeeding act