Síndrome de burnout en el Sistema de Salud: el caso de las trabajadoras sociales sanitarias

Objective: The general goal of this research is to measure the prevalence of the burnout syndrome in the professional group of social health workers who perform their work in the diverse services and centers of the Public Health Service of Galicia (Spain).Method: A quantitative-analytical and cross-sectional design was proposed, using as the main instrument the Maslach Burnout Inventory, Human Services Survey version. This inventory measures three dimensions related to burnout: Emotional Exhaustion, Depersonalization, and Personal Fulfillment. Data collection was carried out through a survey among the social workers registered in the Official Association of Social Work of Galicia.Results: 86.2% of the population under study are women and 13.8% are men; their ages range between 23 and 63 years. The study prevalence data yields high scores, especially in the Emotional Exhaustion dimension, where more than half of the population under study obtained a high score.Conclusion: Like other professional groups that perform their work in the health system, as is the case of Nursing and Medicine, social health workers present high rates of burnout, with Emotional Exhaustion being the most affected dimension.Objetivo: El objetivo general de esta investigación es medir la prevalencia del síndrome de burnout en el colectivo profesional de trabajadoras sociales sanitarias que ejercen su actividad laboral en los diferentes servicios y centros del Servicio Público de Salud de Galicia (España).Método: Se ha planteado un diseño de enfoque cuantitativo-analítico y transversal, utilizando como instrumento principal el cuestionario Maslach Burnout Inventory, versión Human Services Suvey. Dicho cuestionario mide tres dimensiones relacionadas con el burnout: Agotamiento emocional, Despersonalización y Realización personal. La recogida de datos se realizó a través de una aplicación de encuestas entre las trabajadoras sociales colegiadas en el Colegio Oficial de Trabajo Social de Galicia.Resultados: El 86,2% de la población objeto de estudio son mujeres y un 13,8% hombres, y sus edades están comprendidas entre los 23 y los 63 años. Los datos de prevalencia del estudio arrojan unos resultados elevados, especialmente en la dimensión de Agotamiento Emocional donde más de la mitad de la población objeto de estudio presenta una puntuación considerada alta.Conclusión: Al igual que otros colectivos profesionales que ejercen su actividad laboral en el sistema de salud, como es el caso de Enfermería y Medicina, las trabajadoras sociales sanitarias presentan índices elevados de burnout, siendo el Agotamiento Emocional la dimensión más afectada

Response Surface Optimization of Inulin and Polyphenol Extraction from Artichoke (Cynara scolymus (L.)) Solid Wastes

[EN] Featured Application Recovery of bioactive compounds from artichoke solid wastes. Artichoke wastes after processing represent 60-70% of the raw material and are a potential source of inulin and polyphenols, bioactive compounds that can be valorized as food ingredients or nutraceutical products. The aim of this work was to assess and optimize the extraction of these compounds from artichoke wastes using water or water-ethanol mixtures as extracting agents. For simultaneous inulin and polyphenol extraction and to achieve high antioxidant activity in extracts, the best process conditions using water as an extracting agent were T = 89 degrees C and t = 139 min, where 80% of the inulin content, 60% of the total phenolic content (TPC) and 56% of the antioxidant activity (Aox) were obtained. For water-ethanol extractions, the best results were obtained with EtOH = 22.4%, T = 81 degrees C and t = 217 min, leading to extraction yields of 90% of TPC, 38% of Aox and 58% of inulin content. From these results, we recommend the use of water for the recovery of inulin and polyphenols from artichoke wastes. Although the extraction yield of polyphenols is lower in water treatments, the amount extracted is considerable and it is a greener option when compared with water-ethanol mixtures.Garcia-Castello, EM.; Mayor, L.; Calvo-Ramirez, A.; Ruiz-Melero, R.; Rodríguez López, AD. (2022). Response Surface Optimization of Inulin and Polyphenol Extraction from Artichoke (Cynara scolymus (L.)) Solid Wastes. Applied Sciences. 12(6):1-15. https://doi.org/10.3390/app1216795711512

Improving multipath routing of TCP flows by network exploration

Ethernet switched networks are widely used in enterprise and data center networks. However, they have some drawbacks, mainly that, to prevent loops, they cannot take advantage of multipath topologies to balance traffic. Several multipath routing proposals use link-state protocols and Equal Cost Multi-Path routing (ECMP) to distribute the load over multiple paths. But, these proposals are complex and prone to flow collisions that may degrade performance. This paper studies TCP-Path, a protocol that employs a different approach. It uses a distributed network exploration mechanism based on broadcasting the TCPSYN packet to identify and select the fastest available path to the destination host, on the fly. Our evaluation shows that it improves on ECMP by up to 70% in terms of throughput for elephant flows and by up to 60% in terms of flow completion time for mouse flows. Indeed, network exploration offers a better, yet simple alternative to ECMP-based solutions for multipath topologies. In addition, we also study TCP-Path for elephant flows (TFE), which restricts TCP-Path application to elephant flows to reduce the exploration broadcast overhead and the size of forwarding tables, thus improving its scalability. Although elephant flows represent a small fraction (about 5%) of total flows, they have a major impact on overall performance, as we show in our evaluation. TFE reduces both the overhead incurred during path setup and the size of the forwarding tables by a factor of almost 20. Moreover, it achieves results close to those obtained by TCPPath for elephant flows, especially when working with high loads, and yields significant improvements for all types of flow at medium and high load levels.Comunidad de MadridUniversidad de Alcal

Characterization of Ionic Exchange and Macroporous Resins for Their Application on the Separation and Recovery of Chlorogenic Acid from the Wastewater of Artichoke Blanching

[EN] Food wastes have traditionally been considered as dead-end materials; however, recent international, national, and regional policies strongly promote the use of these wastes as potential resources. This change of perception considers the need for sustainable exploitation of natural resources. In this context, artichoke processing produces high amounts of wastewaters, and specifically, wastewaters from the artichoke blanching step present a high content of valuable biocomponents such as carbohydrates and phenolic compounds (e.g., chlorogenic acid, 1700 ppm). In this work, the recovery of chlorogenic acid by applying sorption processes was studied. Five resins were tested, and it was found that the resin XAD 7 HP presented the best total adsorption-desorption yield (72.8%) at 20 degrees C. It was also found that there was a strong variation of the adsorption ratio depending on solution pH (3-7). Four models of isotherms were applied to the adsorption processes, and the Langmuir isotherm better explained the adsorption behavior. The kinetic study showed that the adsorption and desorption of chlorogenic acid followed a pseudo-second order model where the kinetic constant depended on the adsorbate concentration. In addition, it was found that the sorption process was controlled by more than just the intraparticle diffusion mechanism.Rodríguez López, AD.; Reig Riera, MM.; Mayor, L.; Ortiz-Climent, M.; Garcia-Castello, EM. (2021). Characterization of Ionic Exchange and Macroporous Resins for Their Application on the Separation and Recovery of Chlorogenic Acid from the Wastewater of Artichoke Blanching. Sustainability. 13(16):1-15. https://doi.org/10.3390/su13168928S115131

Qualitative methodology for a palliative care resources and services questionnaire validation

Objetivo: Establecer la validez de composición, contenido y criterios de un cuestionario de recursos para la provisión de servicios en Cuidados Paliativos (CP) a través de una metodología cualitativa, mediante grupos focales con profesionales de CP; en el marco de un proyecto de validación y evaluación de los resultados de un cuestionario de recursos para la provisión de servicios en (CP) en la Comunidad de Madrid (CM). Método: Se lleva a cabo un abordaje cualitativo para la validación del cuestionario de recursos. Se selecciona el grupo de discusión como técnica de elección para obtener un discurso en base a la experiencia personal de los profesionales implicados en el ámbito de los CP. Los grupos se componen de médicos, enfermeras, psicólogos, trabajadores sociales y agente de pastoral. Resultado: Los temas de discusión en los grupos fueron: dispersión geográfica de los recursos humanos, motivación laboral y personal, “ayuda psico-emocional” para profesionales, valoración integral y holística del paciente, equidad de los equipos, presupuesto social, apoyo al cuidador, ayuda entre equipos, sobrecarga laboral y humana, relación con la gerencia, futuro de los equipos: “estar quemados”, trabajo en equipo, formación en CP, labor enfermería en CP, protocolo de acogida en CP y aclaraciones terminológicas o conceptuales. Conclusiones: Este trabajo pretende ser el punto de partida para la elaboración y validación de un cuestionario en la provisión de servicios en CP, y así evaluar los recursos humanos y técnicos de nuestra red asistencial sanitaria paliativa.Objective: To establish the composition, content and criteria validity of a questionnaire of resources for services provision in Palliative Care (PC) through a qualitative methodology using focus groups with PC professionals. This is a part of a validation and evaluation research project for the provision of services (CP) in the Community of Madrid (CM). Methods: We performed a qualitative approach to the resource questionnaire validation. It was selected the focus group technique based on the personal experience of the professionals involved in PC. The groups were made up of physicians, nurses, psychologists, social workers and pastoral agent. Results: Discussion items in the groups were: human resources, geographical dispersion, work and personal motivation, “psycho-emotional” help for professionals, comprehensive and holistic patient approach, equipment equity, social budget, caregiver support , support between teams, overburden and human relationship with CEOs, future of teams: “be burned”, team-working, teaching in PC, PC nursing work, PC welcome protocol and terminological and conceptual clarifications. Conclusions: This study tries to be the starting point for the development questionnaire. It will be useful to assess the human and technical resources of our palliative health care network

Adherence and long-term outcomes of growth hormone therapy with easypod™ in pediatric subjects: Spanish ECOS study

E-health; Easypod; Electronic deviceE-salut; Easypod; Dispositiu electrònicE-salud; Easypod; Dispositivo electrónicoBackground: Non-adherence to r-hGH treatments occurs in a variable percentage of subjects. One problem found when evaluating adherence is the great variability in methods of detection and definitions utilized in studies. This study assessed the level of adherence in subjects receiving r-hGH with the easypod™ electronic device. Methods: National, multicenter, prospective and observational study involving 238 subjects (144 with GH deficiency (GHD), and 86 with small for gestational age (SGA), 8 with Turner Syndrome), who received r-hGH with easypod™ for at least 3 months before inclusion. The follow-up period was 4 years. Results: Overall adherence was 94.5%; 97.5% after 6 months, 95.3% after 1 year, 93.7% after 2, 94.4% after 3 and 95.5% after 4 years of treatment. No differences in adherence were observed between prepubertal and pubertal groups and GHD and SGA groups. Change in height after 1 and 2 years, change in height SDS after 1 and 2 years, HV after 1 year, HV SDS after at 1 and 4 years, change in BMI after 1 year and change in BMI SDS at 1 and 2 years showed significant correlation with adherence. No significant differences in adherence according to IGF-I levels were found in follow-up visits or between groups. Conclusions: The easypod™ electronic device, apart from being a precise and objective measure of adherence to r-hGH treatment, allows high compliance rates to be achieved over long periods of time. Adherence significantly impacts growth outcomes associated with r-hGH treatmentThis study was funded by Merck, S.L., Madrid, Spain

A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2-a]quinoxaline Core

Protein tyrosine phosphatase 1B (PTP1B) is a very promising target for the treatment of metabolic disorders such as type II diabetes mellitus. Although it was validated as a promising target for this disease more than 30 years ago, as yet there is no drug in advanced clinical trials, and its biochemical mechanism and functions are still being studied. In the present study, based on our experience generating PTP1B inhibitors, we have developed and implemented a scaffold-hopping approach to vary the pyrrole ring of the pyrrolo[1,2-a]quinoxaline core, supported by extensive computational techniques aimed to explain the molecular interaction with PTP1B. Using a combination of docking, molecular dynamics and end-point free-energy calculations, we have rationally designed a hypothesis for new PTP1B inhibitors, supporting their recognition mechanism at a molecular level. After the design phase, we were able to easily synthesize proposed candidates and their evaluation against PTP1B was found to be in good concordance with our predictions. Moreover, the best candidates exhibited glucose uptake increments in cellulo model, thus confirming their utility for PTP1B inhibition and validating this approach for inhibitors design and molecules thus obtained

Adaptation of scales of attitudes toward tobacco, alcohol and other drugs to Portuguese adolescents

El presente estudio muestra los resultados de la adaptación de las escalas de actitudes hacia el tabaco (López-Sánchez, Garcia-Rodriguez, Mira y Estévez, 2000), el alcohol (Garcia-Rodriguez y López-Sánchez, 2001) y otras drogas (López-Sánchez et al., 2000) en población portuguesa. Se trata de tres escalas, cada una con trece ítems, de respuesta tipo Likert con cinco opciones de respuesta, que diferencian tres sub-escalas. Para realizar el estudio de adaptación de las escalas a la población portuguesa, se han utilizado dos muestras independientes, constituidas por 329 y 443 adolescentes, alumnos de bachillerato del norte del país, a quienes se administraron los instrumentos. Los datos recogidos, después de ser sometidos a un análisis factorial exploratorio y confirmatorio, permitieron encontrar una solución adecuada para cada una de las escalas, dando como resultando una buena validez y fiabilidad. En la validez concurrente, los resultados sugieren diferencias de género con todas las sub-escalas y una relación negativa con la edad, así como diferencias en las actitudes de acuerdo con la experiencia y el consumo.This study presents results about attitudes toward tobacco scale (López-Sánchez, García-Rodriguez, Mira & Estévez, 2000), alcohol scale (García-Rodríguez & López-Sánchez, 2001) and other drugs (López-Sánchez et al., 2000) scale adaptations to portuguese population. There are three scales, 13 items each one and five points Likert response scale with three sub scales. We have used two independent samples with 329 and 443 adolescents, north country high school students. Data collected, after confirmatory and exploratoy analysis, showed a good solution to each one scale, with high validity and reliability rates. Results in concurrent validity suggest gender differences with all the sub scales and a negative relation with age, as well as attitude differences based on experience and consumption

A Comprehensive Survey of In-Band Control in SDN: Challenges and Opportunities

Software-Defined Networking (SDN) is a thriving networking architecture that has gained popularity in recent years, particularly as an enabling technology to foster paradigms like edge computing. SDN separates the control and data planes, which are later on synchronised via a control protocol such as OpenFlow. In-band control is a type of SDN control plane deployment in which the control and data planes share the same physical network. It poses several challenges, such as security vulnerabilities, network congestion, or data loss. Nevertheless, despite these challenges, in-band control also presents significant opportunities, including improved network flexibility and programmability, reduced costs, and increased reliability. Benefiting from the previous advantages, diverse in-band control designs exist in the literature, with the objective of improving the operation of SDN networks. This paper surveys the different approaches that have been proposed so far towards the advance in in-band SDN control, based on four main categories: automatic routing, fast failure recovery, network bootstrapping, and distributed control. Across these categories, detailed summary tables and comparisons are presented, followed by a discussion on current trends a challenges in the field. Our conclusion is that the use of in-band control in SDN networks is expected to drive innovation and growth in the networking industry, but efforts for holistic and full-fledged proposals are still needed

Fabrication and performance of low-fouling UF membranes for 2 the treatment of Isolated Soy Protein solutions

[EN] Consumers are becoming more conscious about the need to include functional and nutritional foods in their diet. This has increased the demand for food extracts rich in proteins and peptides with physiological effects that are used within the food and pharmaceutical industries. Among these protein extracts, soy protein and its derivatives are highlighted. Isolated soy protein (ISP) presents a protein content of at least 90%. Wastewaters generated during the production process contain small proteins (8-50 kDa), and it would be desirable to find a recovery treatment for these compounds. Ultrafiltration membranes (UF) are used for the fractionation and concentration of protein solutions. By the appropriate selection of the membrane pore size, larger soy proteins are retained and concentrated while carbohydrates and minerals are mostly recovered in the permeate. The accumulation and concentration of macromolecules in the proximity of the membrane surface generates one of the most important limitations inherent to the membrane technologies. In this work, three UF membranes based on polyethersulfone (PES) were fabricated. In two of them, polyethylene glycol (PEG) was added in their formulation to be used as a fouling prevention. The membrane fouling was evaluated by the study of flux decline models based on Hermia's mechanisms.The Universitat Politecnica de Valencia (Spain), through the project 2623 (PAID-05-10), funded this research.Garcia-Castello, EM.; Rodríguez López, AD.; Barredo Damas, S.; Iborra Clar, A.; Pascual-Garrido, J.; Iborra-Clar, MI. (2021). Fabrication and performance of low-fouling UF membranes for 2 the treatment of Isolated Soy Protein solutions. Sustainability. 13(24):1-16. https://doi.org/10.3390/su132413682S116132