Una mirada atrás

Treballs de l'alumnat del Grau de Comunicació Audiovisual, Facultat de Biblioteconomia i Documentació, Universitat de Barcelona, Projectes I - Grup7. Curs: 2014-2015, Tutor: Jaume VilasecaDirector: Carla Martínez; Aj. direcció: Enric Bartra ; Productor: Carla Lombardo; Guionista: Carla Lombardo; Director de fotografia: MAria Rodríguez; Camera: Sara Bernal; Aj. Camera: Enric Bartra; Il·luminador: Aina Gutiérrez; Direcció artística: Sara Bernal; Direcció de so: Maria Rodríguez; Muntatge: Sara Bernal; Música: Carla Martínez; Postproducció: Sara Bernal; Equip artístic: Personatge: Pare Gaspar, Actor/Actriu: Enric Bartra; Personatge: Milicià 1, Actor/Actriu: Aina Gutiérrez; Personatge: Milicià 2, Actor/Actriu: Carla Martínez; Personatge: Germana Gaspar, Actor/Actriu: Sara Bernal.[Vídeo] Gaspar Lombardo explica com va viure la Guerra Civil Espanyola quan tenia només 7 anys. Va patir la pèrdua del seu pare a mans de dos miliciansi va veure com propietats i terres de la seva família els hi eren expropiades.[Memòria] En primera instancia, hemos decidido tratar la experiencia que vivió la generación de nuestros abuelos durante la Guerra Civil Española. A partir de aquí, nos hemos acogido al género documental para narrar las vivencias de esos años, con la idea u objetivo principal de mostrar la historia contada en primera persona por alguien que vivió el conflicto bélico o las carencias emocionales y económicas sufridas en la posguerra. Escoger el género documental nos ha permitido expresar con mayor eficacia el hilo argumental del relato. Además, a través de la entrevista hay una conexión más cercana con el público ya que el protagonista y su narración son reales y no están interpretados por un actor. También hemos querido complementar la entrevista con fragmentos ficcionados de las palabras del protagonista, con la intención de causar mayor impacto en el espectador. Después de comparar las historias de los posibles entrevistados, hemos elegido la de Gaspar Lombardo Mata porque es la que mejor plasma la dureza de la Guerra Civil: con solo siete años sufrió la pérdida de su padre en manos de unos milicianos. Debido al contenido dramático y la temática principal, este documental va dirigido al público adulto, ya que relata un hecho muy presente en la sociedad española

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

The IPDGC (The International Parkinson Disease Genomics Consortium) and EADB (Alzheimer Disease European DNA biobank) are listed correctly as an author to the article, however, they were incorrectly listed more than once

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

The IPDGC (The International Parkinson Disease Genomics Consortium) and EADB (Alzheimer Disease European DNA biobank) are listed correctly as an author to the article, however, they were incorrectly listed more than once

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

The IPDGC (The International Parkinson Disease Genomics Consortium) and EADB (Alzheimer Disease European DNA biobank) are listed correctly as an author to the article, however, they were incorrectly listed more than once

Gauss rules associated with nearly singular weights

We consider the problem of evaluating View the MathML source, when f is smooth and G is nearly singular and non-negative. For this we construct a Gauss quadrature formula w.r.t. the weight G(x)(1−x2)−1/2. Once the factor G has been chosen, the procedure is relatively simple and mainly involves the application of FFT to compute a finite number of coefficients of the Chebyshev series expansion of G which in turn are used to calculate modified moments. It is shown that this approach is very effective when the complexity of f is high, or when f is parametric and the integral must be calculated for many values of the parameters. For this, there is presented a selection of numerical examples which allows comparison with other methods. In particular, there is considered the evaluation of Hadamard finite part integrals when the regular part of the integrand is nearly singular.Ministerio de Ciencia e Innovación | Ref. MTM2011-2271

Efecto crónico del Body Jump sobre medidas de condición física y salud: un estudio piloto

BodyJump® is a discipline that has broken out strongly in recent years in fitness centers. However, there is no evidence to support its use as an effective and safe program for improving fitness and health. Therefore, the main objective of this study was to analyze the effect of a short-term BodyJump® program on fitness and health. A total of three sedentary adult women (age: 23 years, 55.3 ± 2.8 kg, 161.3 ± 7.1 cm) completed this case study undergoing a BodyJump® program for four weeks. A total of 17 measures of fitness and health and two measures related to symptoms of Achilles and patellar tendon were defined as dependent variables. The effect of the BodyJump® program on the dependent variables was determined through the statistical effect size. A small effect size (d = 0.5-1.25) was found in measures related to trunk musculature strength and endurance, power of countermovement vertical jump and dynamic balance. For the rest of physical and health measures, a trivial or non-relevant change was observed after the intervention (d <0.5). The findings of the current study report that a short BodyJump® program could be considered an efficient activity for improving trunk muscle strength, endurance, and dynamic balance in sedentary young-adult women.El BodyJump® es una disciplina que ha irrumpido fuertemente en los últimos años en los centros deportivos. Pese a ello, no hay evidencias que permitan respaldar su uso como programa eficaz y seguro para la mejora de la condición física y salud. Por lo tanto, el objetivo principal de este estudio fue analizar el efecto de un programa de corta duración de BodyJump® sobre la condición física y salud. Un total de tres mujeres adultas sedentarias (edad: 23 años; 55,3 ± 2,8 kg; 161,3 ± 7,1 cm) completaron este estudio de casos siendo sometidas a un programa de BodyJump® durante cuatro semanas. Un total de 17 medidas de condición física y salud y dos medidas relacionadas con sintomatología del tendón de Aquiles y rotuliano fueron definidas como variables dependientes. El efecto del programa de BodyJump® sobre las variables dependientes fue determinado a través del estadístico tamaño del efecto. Un tamaño del efecto pequeño (d = 0,5-1,25) fue encontrado en las medidas relacionadas con la fuerza y resistencia de la musculatura del tronco, potencia de salto vertical con contra-movimiento y equilibrio dinámico. Para el resto de medidas de condición física y salud se observó un cambio trivial o no relevante tras la intervención (d < 0,5). Los hallazgos del presente estudios informan de que un programa de BodyJump®podría ser considerado una actividad eficiente para la mejora de la fuerza y resistencia muscular del tronco, potencia y equilibrio dinámico en mujeres adultas jóvenes sedentarias

Perinatal HCV Transmission Rate in HIV/HCV Coinfected women with access to ART in Madrid, Spain.

BACKGROUND:Maternal HIV coinfection is a key factor for mother-to-child transmission (MTCT) of HCV. However, data about HCV MTCT in HIV/HCV-coinfected pregnant women on combined antiretroviral treatment (ART) are scarce. This study assessed the HCV MTCT rate in the Madrid Cohort of HIV-infected women. METHODS:Retrospective study within the Madrid Cohort of HIV-infected pregnant women (2000-2012). Epidemiological, clinical and treatment related variables were analysed for the mother and infant pairs. HCV MTCT rate was determined. RESULTS:Three hundred thirty-nine HIV/HCV-coinfected women and their exposed infants were recorded. A total of 227 (67%) paired mother-children had available data of HCV follow-up and were included for the analysis. Sixteen children (rate 7.0%, 95%CI 3.7-10.4%) were HCV infected by 18 months of age, none of them coinfected with HIV. HIV/HCV-coinfected pregnant women were mostly of Spanish origin with a background of previous injection drug use. HCV-genotype 1 was predominant. The characteristics of mothers that transmitted HCV were similar to those that did not transmit HCV with respect to sociodemographic and clinical features. A high rate (50%) of preterm deliveries was observed. Infants infected with HCV were similar at birth in weight, length and head circumference than those uninfected. CONCLUSION:MTCT rates of HCV among HIV/HCV-coinfected women on ART within the Madrid cohort were lower than previously described. However, rates are still significant and strategies to eliminate any HCV transmission from mother to child are needed

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

The genetic variant rs72824905-G (minor allele) in the PLCG2 gene was previously associated with a reduced Alzheimer’s disease risk (AD). The role of PLCG2 in immune system signaling suggests it may also protect against other neurodegenerative diseases and possibly associates with longevity. We studied the effect of the rs72824905-G on seven neurodegenerative diseases and longevity, using 53,627 patients, 3,516 long-lived individuals and 149,290 study-matched controls. We replicated the association of rs72824905-G with reduced AD risk and we found an association with reduced risk of dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD). We did not find evidence for an effect on Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) risks, despite adequate sample sizes. Conversely, the rs72824905-G allele was associated with increased likelihood of longevity. By-proxy analyses in the UK Biobank supported the associations with both dementia and longevity. Concluding, rs72824905-G has a protective effect against multiple neurodegenerative diseases indicating shared aspects of disease etiology. Our findings merit studying the PLCγ2 pathway as drug-target.Pattern Recognition and Bioinformatic

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

The genetic variant rs72824905-G (minor allele) in the PLCG2 gene was previously associated with a reduced Alzheimer's disease risk (AD). The role of PLCG2 in immune system signaling suggests it may also protect against other neurodegenerative diseases and possibly associates with longevity. We studied the effect of the rs72824905-G on seven neurodegenerative diseases and longevity, using 53,627 patients, 3,516 long-lived individuals and 149,290 study-matched controls. We replicated the association of rs72824905-G with reduced AD risk and we found an association with reduced risk of dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD). We did not find evidence for an effect on Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) risks, despite adequate sample sizes. Conversely, the rs72824905-G allele was associated with increased likelihood of longevity. By-proxy analyses in the UK Biobank supported the associations with both dementia and longevity. Concluding, rs72824905-G has a protective effect against multiple neurodegenerative diseases indicating shared aspects of disease etiology. Our findings merit studying the PLCγ2 pathway as drug-target

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

The IPDGC (The International Parkinson Disease Genomics Consortium) and EADB (Alzheimer Disease European DNA biobank) are listed correctly as an author to the article, however, they were incorrectly listed more than once