4,230 research outputs found
The role of expectations on consumer interpretation of new information
© 2017, © Emerald Publishing Limited. Purpose: The purpose of this paper is to investigate the role of consumersâ expectations and their antecedents on beliefs, attitude and behavioral intentions when they respond to new corporate social responsibility (CSR) information about a service firm. Design/methodology/approach: Empirically, the authors measure prior beliefs, and then calibrate how those beliefs change in response to a piece of news. The authors develop a conceptual model articulating the nature and antecedents of three types of expectations: would, could and should. The authors use structural equation modeling to test how these expectations influence the consumer evaluation process. Findings: The results show that the effect of could expectations on the evaluation process is felt via their influence on would expectations; that is, would expectations fully mediate the relationship between could expectations and attitude toward news. Similarly, attitude toward news fully mediates the relationship between would and should expectations and updated beliefs about the firm. Research limitations/implications: In the selected service industry, the findings show that expectations are mediated by the new information that consumers receive when they are updating their prior beliefs. The authors demonstrate the ability to understand the antecedents of expectations, which provides a vehicle by which the organization can influence the consumer evaluation process. Practical implications: In practice, managers can identify the antecedents of consumer expectations and thus influence the reference points against which those consumers will evaluate news about their product. Social implications: CSR has important implications for multiple stakeholders and the authors calibrate the determinants of how news about the organizationâs performance on it may affect consumer decision processes. Originality/value: The paper introduces âcouldâ expectations into the services literature, examines the antecedents of the different types of expectations, and studies how their effect is felt through the evaluation process
Coherence of terrestrial vertebrate species richness with external drivers across scales and taxonomic groups
Aim: Understanding connections between environment and biodiversity is crucial for conservation, identifying causes of ecosystem stress, and predicting population responses to changing environments. Explaining biodiversity requires an under-standing of how species richness and environment covary across scales. Here, we identify scales and locations at which biodiversity is generated and correlates with environment.Location: Full latitudinal range per continent.Time Period: Present day.Major Taxa Studied: Terrestrial vertebrates: all mammals, carnivorans, bats, song-birds, hummingbirds, amphibians.Methods: We describe the use of wavelet power spectra, cross- power and coherence for identifying scale-dependent trends across Earth's surface. Spectra reveal scale- and location-dependent coherence between species richness and topography (E), mean annual precipitation (Pn), temperature (Tm) and annual temperature range (ÎT).Results: >97% of species richness of taxa studied is generated at large scales, that is, wavelengths âł103 km, with 30%â69% generated at scales âł104 km. At these scales, richness tends to be highly coherent and anti-correlated with E and ÎT, and positively correlated with Pn and Tm. Coherence between carnivoran richness and ÎT is low across scales, implying insensitivity to seasonal temperature variations. Conversely, amphibian richness is strongly anti-correlated with ÎT at large scales. At scales âČ103 km, examined taxa, except carnivorans, show highest richness within the trop-ics. Terrestrial plateaux exhibit high coherence between carnivorans and E at scales âŒ103 km, consistent with contribution of large-scale tectonic processes to biodiver-sity. Results are similar across different continents and for global latitudinal averages. Spectral admittance permits derivation of rules-of- thumb relating long-wavelength environmental and species richness trends.Main Conclusions: Sensitivities of mammal, bird and amphibian populations to envi-ronment are highly scale dependent. At large scales, carnivoran richness is largely in-dependent of temperature and precipitation, whereas amphibian richness correlates strongly with precipitation and temperature, and anti-correlates with temperature range. These results pave the way for spectral- based calibration of models that pre-dict biodiversity response to climate change scenarios
Developmental changes in spinal neuronal properties, motor network configuration, and neuromodulation at free-swimming stages of Xenopus tadpoles
We describe a novel preparation of the isolated brainstem and spinal cord from pro-metamorphic tadpole stages of the South African clawed frog (Xenopus laevis) that permits whole cell patch-clamp recordings from neurons in the ventral spinal cord. Previous research on earlier stages of the same species has provided one of the most detailed understandings of the design and operation of a CPG circuit. Here we have addressed how development sculpts complexity from this more basic circuit. The preparation generates bouts of fictive31 swimming activity either spontaneously or in response to electrical stimulation of the optic tectum, allowing an investigation into how the neuronal properties, activity patterns and neuromodulation of locomotor rhythm generation change during development. We describe an increased repertoire of cellular responses compared to younger larval stages and investigate the cellular level effects of nitrergic neuromodulation as well as the development of a sodium pump-mediated ultra-slow afterhyperpolarisation (usAHP) in these free-swimming larval animals.PostprintPeer reviewe
Non-linear dynamic response of a cable system with a tuned mass damper to stochastic base excitation via equivalent linearization technique
Abstract: Non-linear dynamic model of a cableâmass system with a transverse tuned mass damper is considered. The system is moving in a vertical host structure therefore the cable length varies slowly over time. Under the time-dependent external loads the sway of host structure with low frequencies and high amplitudes can be observed. That yields the base excitation which in turn results in the excitation of a cable system. The original model is governed by a system of non-linear partial differential equations with corresponding boundary conditions defined in a slowly time-variant space domain. To discretise the continuous model the Galerkin method is used. The assumption of the analysis is that the lateral displacements of the cable are coupled with its longitudinal elastic stretching. This brings the quadratic couplings between the longitudinal and transverse modes and cubic nonlinear terms due to the couplings between the transverse modes. To mitigate the dynamic response of the cable in the resonance region the tuned mass damper is applied. The stochastic base excitation, assumed as a narrow-band process mean-square equivalent to the harmonic process, is idealized with the aid of two linear filters: one second-order and one first-order. To determine the stochastic response the equivalent linearization technique is used. Mean values and variances of particular random state variable have been calculated numerically under various operational conditions. The stochastic results have been compared with the deterministic response to a harmonic process base excitation
Levonorgestrel-releasing intrauterine system vs. usual medical treatment for menorrhagia: An economic evaluation alongside a randomised controlled trial
Objective: To undertake an economic evaluation alongside the largest randomised controlled trial comparing Levonorgestrel-releasing intrauterine device ('LNG-IUS') and usual medical treatment for women with menorrhagia in primary care; and compare the cost-effectiveness findings using two alternative measures of quality of life. Methods: 571 women with menorrhagia from 63 UK centres were randomised between February 2005 and July 2009. Women were randomised to having a LNG-IUS fitted, or usual medical treatment, after discussing with their general practitioner their contraceptive needs or desire to avoid hormonal treatment. The treatment was specified prior to randomisation. For the economic evaluation we developed a state transition (Markov) model with a 24 month follow-up. The model structure was informed by the trial women's pathway and clinical experts. The economic evaluation adopted a UK National Health Service perspective and was based on an outcome of incremental cost per Quality Adjusted Life Year (QALY) estimated using both EQ-5D and SF-6D. Results: Using EQ-5D, LNG-IUS was the most cost-effective treatment for menorrhagia. LNG-IUS costs £100 more than usual medical treatment but generated 0.07 more QALYs. The incremental cost-effectiveness ratio for LNG-IUS compared to usual medical treatment was £1600 per additional QALY. Using SF-6D, usual medical treatment was the most cost-effective treatment. Usual medical treatment was both less costly (£100) and generated 0.002 more QALYs. Conclusion: Impact on quality of life is the primary indicator of treatment success in menorrhagia. However, the most costeffective treatment differs depending on the quality of life measure used to estimate the QALY. Under UK guidelines LNG-IUS would be the recommended treatment for menorrhagia. This study demonstrates that the appropriate valuation of outcomes in menorrhagia is crucial. Copyright: © 2014 Sanghera et al
Knowledge and attitudes of parents and professionals to neonatal BCG vaccination in light of recent UK policy changes: A questionnaire study
<p>Abstract</p> <p>Background</p> <p>Universal BCG vaccination in the UK ended in 2005. The new vaccination policy instead offers a number of different forms of selective vaccination to newborns based on risk of acquiring TB. We set out to assess the attitudes and knowledge of both parents and professionals to the new policy for neonatal BCG vaccination.</p> <p>Methods</p> <p>A short questionnaire was designed, made up of demographic and attitude questions, as well as very basic knowledge questions. The researchers handed out the questionnaire to all parents and professionals in the antenatal and postnatal areas, as well as the paediatric and neonatal units during a 6-week period. The site was the Royal Oldham hospital, a district general hospital with 3250 deliveries per year and multi-ethnic in its population mix.</p> <p>Results</p> <p>A total of 253 completed questionnaires were collected. The ethnic origin of responders was 50.6% White British, 18.2% Bangladeshi, 8.7% Indian, 4% White/Asian, the remaining 18.5% of other origins. 71.5% of responders said they had heard of BCG vaccine. When asked if they knew the new policy for its use, 33.2% answered yes. 24.5% gave the most accurate response when asked who now receives BCG.</p> <p>Conclusion</p> <p>We have found that amongst parents and professionals alike there is a lack of knowledge of the new policy. This has lead to confusion and as knowledge amongst the professionals who identify neonates for vaccination is low, uptake may be sub-optimal. We suggest that units investigate the issue and ensure that the new policy is understood and implemented correctly.</p
Diet of the South African large-spotted genet Genetta tigrina (Carnivora, Viverridae) in a coastal dune forest
We studied seasonal variations in the diet of the large-spotted genet Genetta tigrina Schreber, 1776 in the coastal dune forest of the Dwesa Nature Reserve, Eastern Cape Province, South Africa. The food items with the highest relative percentage occurrence were Coleoptera, Orthoptera and Mammalia.
However, by volume they ate mostly grass then followed by Coleoptera and Orthoptera. Main prey items originated from the litter layer or low lying bushes, such as arachnids, insects, myriapods, and most mammals. The latter included ten rodent (main staple: Dendromus sp.), two golden mole and two
shrew species, from 10â100 g mass. They were represented dependent on species density, but switching between seasons and habitats occupied. Birds appeared under-represented in the diet for a semi-arboreal carnivore, although this correlates with data from other studies. Remains of birds in the diet, however, peaked during winter and spring probably as a result of the main nesting period in spring. There were some variation in diet between habitats (riparian, forest and beach) and seasons. Our results show the South African large-spotted genet to have an opportunistic, generalist diet.NERC, Eastern Cape Parks, NRF, CI
In situ neutron scattering of antibody adsorption during protein A chromatography
A deeper understanding of the nanoscale and mesoscale structure of chromatographic adsorbents and the distribution of proteins within the media, is critical to a mechanistic understanding of separation processes using these materials. Characterisation of the media's architecture at this scale and protein adsorption within, is challenging using conventional techniques. In this study, we propose a novel resin characterisation technique that enables in-situ measurement of the structure of the adsorbed protein layer within the resin, under typical chromatographic conditions. A quartz flow-through cell was designed and fabricated for use with Small Angle Neutron Scattering (SANS), in order to measure the nanoscale to mesoscale structures of a silica based protein A chromatography resin during the monoclonal antibody sorption process. We were able to examine the pore-to-pore (Ë133 nm) and pore size (Ë63 nm) correlations of the resin and the in-plane adsorbed antibody molecules (Ë 4.2 nm) correlation at different protein loadings and washing buffers, in real time using a contrast matching approach. When 0.03 M sodium phosphate with 1 M urea and 10 % isopropanol buffer, pH 8, was introduced into the system as a wash buffer, it disrupted the system's order by causing partial unfolding of the adsorbed antibody, as evidenced by a loss of the in-plane protein correlation. This method offers new ways to investigate the nanoscale structure and ligand immobilisation within chromatography resins; and perhaps most importantly understand the in-situ behaviour of adsorbed proteins within the media under different mobile phase conditions within a sample environment replicating that of a chromatography column
Atom--Molecule Coherence in a Bose-Einstein Condensate
Coherent coupling between atoms and molecules in a Bose-Einstein condensate
(BEC) has been observed. Oscillations between atomic and molecular states were
excited by sudden changes in the magnetic field near a Feshbach resonance and
persisted for many periods of the oscillation. The oscillation frequency was
measured over a large range of magnetic fields and is in excellent quantitative
agreement with the energy difference between the colliding atom threshold
energy and the energy of the bound molecular state. This agreement indicates
that we have created a quantum superposition of atoms and diatomic molecules,
which are chemically different species.Comment: 7 pages, 6 figure
An Investigation of Racing Performance and Whip Use by Jockeys in Thoroughbred Races
Concerns have been expressed concerning animal-welfare issues associated with whip use during Thoroughbred races. However, there have been no studies of relationships between performance and use of whips in Thoroughbred racing. Our aim was to describe whip use and the horses' performance during races, and to investigate associations between whip use and racing performance. Under the Australian Racing Board (ARB) rules, only horses that are in contention can be whipped, so we expected that whippings would be associated with superior performance, and those superior performances would be explained by an effect of whipping on horse velocities in the final 400 m of the race. We were also interested to determine whether performance in the latter sections of a race was associated with performance in the earlier sections of a race. Measurements of whip strikes and sectional times during each of the final three 200 metre (m) sections of five races were analysed. Jockeys in more advanced placings at the final 400 and 200 m positions in the races whipped their horses more frequently. Horses, on average, achieved highest speeds in the 600 to 400 m section when there was no whip use, and the increased whip use was most frequent in the final two 200 m sections when horses were fatigued. This increased whip use was not associated with significant variation in velocity as a predictor of superior placing at the finish
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