1,613 research outputs found

    Families at Five: Extending Land-Grant Research Findings to Families

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    Families at Five is a joint community outreach partnership between Colorado State University (CSU) Department of Human Development and Family Studies and CSU Cooperative Extension. The program provides research-based family life education and resources to families, Extension educators, and family life community professionals. Comprised of an adult program with accompanying programs for adolescents and children, Families at Five is designed to educate family members on ways to strengthen family relationships. Included in the article are suggestions for engaging Cooperative Extension agents and other community practitioners in the program planning and delivery of educational programs

    How to deal with non-detectable and outlying values in biomarker research: Best practices and recommendations for univariate imputation approaches

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    Non-detectable (ND) and outlying concentration values (OV) are a common challenge of biomarker investigations. However, best practices on how to aptly deal with the affected cases are still missing. The high methodological heterogeneity in biomarker-oriented research, as for example, in the field of psychoneuroendocrinology, and the statistical bias in some of the applied methods may compromise the robustness, comparability, and generalizability of research findings. In this paper, we describe the occurrence of ND and OV in terms of a model that considers them as censored data, for instance due to measurement error cutoffs. We then present common univariate approaches in handling ND and OV by highlighting their respective strengths and drawbacks. In a simulation study with lognormal distributed data, we compare the performance of six selected methods, ranging from simple and commonly used to more sophisticated imputation procedures, in four scenarios with varying patterns of censored values as well as for a broad range of cutoffs. Especially deletion, but also fixed-value imputations bear a high risk of biased and pseudo-precise parameter estimates. We also introduce censored regressions as a more sophisticated option for a direct modeling of the censored data. Our analyses demonstrate the impact of ND and OV handling methods on the results of biomarker-oriented research, supporting the need for transparent reporting and the implementation of best practices. In our simulations, the use of imputed data from the censored intervals of a fitted lognormal distribution shows preferable properties regarding our established criteria. We provide the algorithm for this favored routine for a direct application in R on the Open Science Framework (https://osf.io/spgtv). Further research is needed to evaluate the performance of the algorithm in various contexts, for example when the underlying assumptions do not hold. We conclude with recommendations and potential further improvements for the field

    A Serendipitous Galaxy Cluster Survey with XMM: Expected Catalogue Properties and Scientific Applications

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    This paper describes a serendipitous galaxy cluster survey that we plan to conduct with the XMM X-ray satellite. We have modeled the expected properties of such a survey for three different cosmological models, using an extended Press-Schechter (Press & Schechter 1974) formalism, combined with a detailed characterization of the expected capabilities of the EPIC camera on board XMM. We estimate that, over the ten year design lifetime of XMM, the EPIC camera will image a total of ~800 square degrees in fields suitable for the serendipitous detection of clusters of galaxies. For the presently-favored low-density model with a cosmological constant, our simulations predict that this survey area would yield a catalogue of more than 8000 clusters, ranging from poor to very rich systems, with around 750 detections above z=1. A low-density open Universe yields similar numbers, though with a different redshift distribution, while a critical-density Universe gives considerably fewer clusters. This dependence of catalogue properties on cosmology means that the proposed survey will place strong constraints on the values of Omega-Matter and Omega-Lambda. The survey would also facilitate a variety of follow-up projects, including the quantification of evolution in the cluster X-ray luminosity-temperature relation, the study of high-redshift galaxies via gravitational lensing, follow-up observations of the Sunyaev-Zel'dovich effect and foreground analyses of cosmic microwave background maps.Comment: Accepted to ApJ. Minor changes, e.g. presentation of temperature errors as a figure (rather than as a table). Latex (20 pages, 6 figures, uses emulateapj.sty

    Imaging and spectroscopy of arcs around the most luminous X-ray cluster RX J1347.5-1145

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    The cluster RX J1347.5-1145, the most luminous cluster in the X-ray wavelengths, was imaged with the newly installed Space Telescope Imaging Spectrograph (STIS) on-board HST. Its relatively high redshift (0.451) and luminosity indicate that this is one of the most massive of all known clusters. The STIS images unambiguously show several arcs in the cluster. The largest two arcs (> 5 arcsec in length) are symmetrically situated on opposite sides of the cluster, at a distance of ~ 35 arcsec from the central galaxy. The STIS images also show approximately 100 faint galaxies within the radius of the arcs whose combined luminosity is ~ 4 x 10^11 Lsun. We also present ground-based spectroscopic observations of the northern arc which show one clear emission line at 6730 A, which is consistent with an identification as [OII] 3727 A, implying a redshift of 0.81 for this arc. The southern arc shows a faint continuum but no emission features. The surface mass within the radius of the arcs (240 kpc), as derived from the gravitational lensing, is 6.3 x 10^14 Msun. The resultant mass-to-light ratio of ~1200 is higher than what is seen in many clusters but smaller than the value recently derived for some `dark' X-ray clusters (Hattori et al. 1997). The total surface mass derived from the X-ray flux within the radius of the arcs is ~2.1 - 6.8 x 10^14 Msun, which implies that the ratio of the gravitational to the X-ray mass is ~1 to 3. The surface GAS mass within this radius is ~3.5 x 10^13 Msun, which implies that at least 6% of the total mass within this region is baryonic.Comment: 3 figures. Replaced with the final version as appears in the Astrophysical Journal Letters (Jan 10, 1998 issue). This incorporates some important revision

    The role of biophysical cohesion on subaqueous bed form size

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    Biologically active, fine-grained sediment forms abundant sedimentary deposits on Earth's surface, and mixed mud-sand dominates many coasts, deltas, and estuaries. Our predictions of sediment transport and bed roughness in these environments presently rely on empirically based bed form predictors that are based exclusively on biologically inactive cohesionless silt, sand, and gravel. This approach underpins many paleoenvironmental reconstructions of sedimentary successions, which rely on analysis of cross-stratification and bounding surfaces produced by migrating bed forms. Here we present controlled laboratory experiments that identify and quantify the influence of physical and biological cohesion on equilibrium bed form morphology. The results show the profound influence of biological cohesion on bed form size and identify how cohesive bonding mechanisms in different sediment mixtures govern the relationships. The findings highlight that existing bed form predictors require reformulation for combined biophysical cohesive effects in order to improve morphodynamic model predictions and to enhance the interpretations of these environments in the geological record
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