The Gould's Belt Very Large Array Survey II: The Serpens region

We present deep ($\sim 17~\mu$Jy) radio continuum observations of the Serpens molecular cloud, the Serpens south cluster, and the W40 region obtained using the Very Large Array in its A configuration. We detect a total of 146 sources, 29 of which are young stellar objects (YSOs), 2 are BV stars and 5 more are associated with phenomena related to YSOs. Based on their radio variability and spectral index, we propose that about 16 of the remaining 110 unclassified sources are also YSOs. For approximately 65% of the known YSOs detected here as radio sources, the emission is most likely non-thermal, and related to stellar coronal activity. As also recently observed in Ophiuchus, our sample of YSOs with X-ray counterparts lies below the fiducial G\"udel & Benz relation. Finally, we analyze the proper motions of 9 sources in the W40 region. This allows us to better constrain the membership of the radio sources in the region.Comment: Accepted in The Astrophysical Journa

The Gould's Belt Very Large Array Survey III. The Orion region

We present results from a high-sensitivity (60 $\mu$Jy), large-scale (2.26 square degree) survey obtained with the Karl G. Jansky Very Large Array as part of the Gould's Belt Survey program. We detected 374 and 354 sources at 4.5 and 7.5 GHz, respectively. Of these, 148 are associated with previously known Young Stellar Objects (YSOs). Another 86 sources previously unclassified at either optical or infrared wavelengths exhibit radio properties that are consistent with those of young stars. The overall properties of our sources at radio wavelengths such as their variability and radio to X-ray luminosity relation are consistent with previous results from the Gould's Belt Survey. Our detections provide target lists for followup VLBA radio observations to determine their distances as YSOs are located in regions of high nebulosity and extinction, making it difficult to measure optical parallaxes.Comment: Accepted for publication in ApJ; 51 pages, 15 figures, 5 table

Scaling Out Evidence-Based Interventions Outside the U.S. Mainland: Social Justice or Trojan Horse?

Global health disparities continue to widen as professional standards for effectiveness of mental health services provision become more precise and difficult to achieve across varied economic and social contexts. Within the U.S., health disparities are evident in Latinx populations. Globally, the health disparities are also evident in Latin America as compared to the U.S. and other economically affluent nations. The diversification of psychology in content and persons has led to a unique opportunity to build bridges that can help reduce disparities in- and outside of the U.S. mainland. Collaborations can be of great use in addressing health disparities internationally but also are of critical importance in testing the ecological validity of existing interventions. It is imperative that researchers approach these exchanges as truly collaborative and power even, as researchers in all locations stand to learn and grow from the partnership, otherwise U.S.-based researchers can unwittingly engage intellectual colonization and advance cultural imperialism. U.S.-based researchers must be particularly thoughtful about disparities in both resources and consequences for success and failures in research contexts. We discuss specific failures, recoveries, and successes that may be useful to other researchers engaged, or seeking to engage in, international collaborations

Poly (lactic acid)/D-limonene/ZnO bio-nanocomposites with antimicrobial properties

Antimicrobial films of poly (lactic acid) (PLA)/D-limonene/zinc oxide (ZnO)-based bio-nanocomposites were prepared via melt compounding and subsequent thermocompression. D-limonene was incorporated at concentrations of 10 or 20 wt%, and ZnO pure nanoparticles and those organically modified with oleic acid (O-ZnO), with an average diameter of 13.5 nm, were included at concentrations of 3, 5, and 8 wt%. The plasticizing effect of D-Limonene was corroborated by a decrease in the glass transition temperature compared to pure PLA. The presence of ZnO and O-ZnO in the PLA matrix promoted a slight increase in the degree of crystallinity due to its nucleant performance. Although ZnO and O-ZnO induced lower thermal stability and slightly decreased microhardness in the composites, excellent antimicrobial performance was demonstrated. Both ZnO and O-ZnO nanocomposites reached 99.9% of effectiveness for nanoparticles content above 5 wt%, regardless of the source of irradiation, D-limonene concentration, and nanoparticle modification. Therefore, these bio-nanocomposites will allow for future advances in sustainable antimicrobial materials for the medical or food packaging fields.DICYT, Grant/Award Number: Project 022041ZR_POSTDOCT; Fondo Nacional de Desarrollo Científico y Tecnológico,Grant/Award Numbers: 1170226, 320029

Filamin B Regulates Chondrocyte Proliferation and Differentiation through Cdk1 Signaling

Humans who harbor loss of function mutations in the actin-associated filamin B (FLNB) gene develop spondylocarpotarsal syndrome (SCT), a disorder characterized by dwarfism (delayed bone formation) and premature fusion of the vertebral, carpal and tarsal bones (premature differentiation). To better understand the cellular and molecular mechanisms governing these seemingly divergent processes, we generated and characterized FlnB knockdown ATDC5 cell lines. We found that FlnB knockdown led to reduced proliferation and enhanced differentiation in chondrocytes. Within the shortened growth plate of postnatal FlnB−/− mice long bone, we observed a similarly progressive decline in the number of rapidly proliferating chondrocytes and premature differentiation characterized by an enlarged prehypertrophic zone, a widened Col2a1+/Col10a1+ overlapping region, but relatively reduced hypertrophic zone length. The reduced chondrocyte proliferation and premature differentiation were, in part, attributable to enhanced G2/M phase progression, where fewer FlnB deficient ATDC5 chondrocytes resided in the G2/M phase of the cell cycle. FlnB loss reduced Cdk1 phosphorylation (an inhibitor of G2/M phase progression) and Cdk1 inhibition in chondrocytes mimicked the null FlnB, premature differentiation phenotype, through a β1-integrin receptor- Pi3k/Akt (a key regulator of chondrocyte differentiation) mediated pathway. In this context, the early prehypertrophic differentiation provides an explanation for the premature differentiation seen in this disorder, whereas the progressive decline in proliferating chondrocytes would ultimately lead to reduced chondrocyte production and shortened bone length. These findings begin to define a role for filamin proteins in directing both cell proliferation and differentiation through indirect regulation of cell cycle associated proteins

The Gould's Belt Very Large Array Survey. IV. The Taurus-Auriga Complex

We present a multi-epoch radio study of the Taurus-Auriga star-forming complex made with the Karl G. Jansky Very Large Array at frequencies of 4.5 GHz and 7.5 GHz. We detect a total of 610 sources, 59 of which are related to young stellar objects (YSOs) and 18 to field stars. The properties of 56% of the young stars are compatible with non-thermal radio emission. We also show that the radio emission of more evolved YSOs tends to be more non-thermal in origin and, in general, that their radio properties are compatible with those found in other star-forming regions. By comparing our results with previously reported X-ray observations, we notice that YSOs in Taurus-Auriga follow a Güdel-Benz relation with κ = 0.03, as we previously suggested for other regions of star formation. In general, YSOs in Taurus-Auriga and in all the previous studied regions seem to follow this relation with a dispersion of ~1 dex. Finally, we propose that most of the remaining sources are related with extragalactic objects but provide a list of 46 unidentified radio sources whose radio properties are compatible with a YSO nature

Radio Measurements of the stellar proper motions in the core of the Orion Nebula Cluster

Sergio A. Dzib, et al, 'RADIO MEASUREMENTS OF THE STELLAR PROPER MOTIONS IN THE CORE OF THE ORION NEBULA CLUSTER', The Astrophysical Journal, Vol. 834(2), 10 pp, January 2017. doi:10.3847/1538-4357/834/2/139 © 2017. The American Astronomical Society. All rights reserved.Using multi-epoch VLA observations, covering a time baseline of 29.1 years, we have measured the proper motions of 88 young stars with compact radio emission in the core of the Orion Nebula Cluster (ONC) and the neighboring BN/KL region. Our work increases the number of young stars with measured proper motion at radio frequencies by a factor of 2.5 and enables us to perform a better statistical analysis of the kinematics of the region than was previously possible. Most stars (79 out of 88) have proper motions consistent with a Gaussian distribution centered on $\overline{\mu_{\alpha}\cos{\delta}}=1.07\pm0.09\quad{\rm mas\,yr^{-1}}$, and $\overline{\mu_{\delta}}=-0.84\pm0.16\quad{\rm mas\,yr^{-1}}$, with velocity dispersions of $\sigma_{\alpha}=1.08\pm0.07\quad{\rm mas\,\,yr^{-1}},$ $\sigma_{\delta}=1.27\pm0.15\quad{\rm mas\,\,yr^{-1}}$. We looked for organized movements of these stars but found no clear indication of radial expansion/contraction or rotation. The remaining nine stars in our sample show peculiar proper motions that differ from the mean proper motions of the ONC by more than 3-$\sigma$. One of these stars, V 1326 Ori, could have been expelled from the Orion Trapezium 7,000 years ago. Two could be related to the multi-stellar disintegration in the BN/KL region, in addition to the previously known sources BN, I and n. The others either have high uncertainties (so their anomalous proper motions are not firmly established) or could be foreground objects.Peer reviewedFinal Published versio