337 research outputs found
In-situ focused ion beam implantation for the fabrication of a hot electron transistor oscillator structure
Recent advances using in situ focused ion beam implantation during an MBE growth interruption have been exploited to fabricate planar GaAs hot electron structures without the need for shallow ohmic contacts. This novel fabrication route shows a very high yield and has been used to demonstrate a prototype high-frequency oscillator structure based on electron multiplication in the base layer. Existing devices show transfer factors in excess of unity as well as reversal of the base current at high injection levels, which are the prerequisites for oscillator action. Future improvements in device design are discussed
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.
Causes of the well-documented association between low levels of cognitive functioning and many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain unknown. We used linkage disequilibrium regression and polygenic profile scoring to test for shared genetic aetiology between cognitive functions and neuropsychiatric disorders and physical health. Using information provided by many published genome-wide association study consortia, we created polygenic profile scores for 24 vascular-metabolic, neuropsychiatric, physiological-anthropometric and cognitive traits in the participants of UK Biobank, a very large population-based sample (N=112?151). Pleiotropy between cognitive and health traits was quantified by deriving genetic correlations using summary genome-wide association study statistics and to the method of linkage disequilibrium score regression. Substantial and significant genetic correlations were observed between cognitive test scores in the UK Biobank sample and many of the mental and physical health-related traits and disorders assessed here. In addition, highly significant associations were observed between the cognitive test scores in the UK Biobank sample and many polygenic profile scores, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, autism, major depressive disorder, body mass index, intracranial volume, infant head circumference and childhood cognitive ability. Where disease diagnosis was available for UK Biobank participants, we were able to show that these results were not confounded by those who had the relevant disease. These findings indicate that a substantial level of pleiotropy exists between cognitive abilities and many human mental and physical health disorders and traits and that it can be used to predict phenotypic variance across samples.Molecular Psychiatry advance online publication, 26 January 2016; doi:10.1038/mp.2015.225
Micromachined III-V cantilevers for AFM-tracking scanning Hall probe microscopy
In this paper we report the development of a new III-V cantilever-based atomic force sensor with piezoresistive detection and an integrated Hall probe for scanning Hall probe microscopy. We give detailed descriptions of the fabrication process and characterization of the new integrated sensor, which will allow the investigation of magnetic samples with no sample preparation at both room and cryogenic temperatures. We also introduce a novel piezoresistive material based on the ternary alloy n+-Al0.4Ga0.6As which allows us to achieve a cantilever deflection sensitivity ÎR/(RÎz) = 2 Ă 10-6 Ă
-1 at room temperature
Intelligence and neuroticism in relation to depression and psychological distress: Evidence from two large population cohorts
BACKGROUND: Neuroticism is a risk factor for selected mental and physical illnesses and is inversely associated with intelligence. Intelligence appears to interact with neuroticism and mitigate its detrimental effects on physical health and mortality. However, the inter-relationships of neuroticism and intelligence for major depressive disorder (MDD) and psychological distress has not been well examined. METHODS: Associations and interactions between neuroticism and general intelligence (g) on MDD, self-reported depression, and psychological distress were examined in two population-based cohorts: Generation Scotland: Scottish Family Health Study (GS:SFHS, n=19,200) and UK Biobank (n=90,529). The Eysenck Personality Scale Short Form-Revised measured neuroticism and g was extracted from multiple cognitive ability tests in each cohort. Family structure was adjusted for in GS:SFHS. RESULTS: Neuroticism was strongly associated with increased risk for depression and higher psychological distress in both samples. Although intelligence conferred no consistent independent effects on depression, it did increase the risk for depression across samples once neuroticism was adjusted for. Results suggest that higher intelligence may ameliorate the association between neuroticism and self-reported depression although no significant interaction was found for clinical MDD. Intelligence was inversely associated with psychological distress across cohorts. A small interaction was found across samples such that lower psychological distress associates with higher intelligence and lower neuroticism, although effect sizes were small. CONCLUSIONS: From two large cohort studies, our findings suggest intelligence acts a protective factor in mitigating the effects of neuroticism on psychological distress. Intelligence does not confer protection against diagnosis of depression in those high in neuroticism
Electron energy loss and induced photon emission in photonic crystals
The interaction of a fast electron with a photonic crystal is investigated by
solving the Maxwell equations exactly for the external field provided by the
electron in the presence of the crystal. The energy loss is obtained from the
retarding force exerted on the electron by the induced electric field. The
features of the energy loss spectra are shown to be related to the photonic
band structure of the crystal. Two different regimes are discussed: for small
lattice constants relative to the wavelength of the associated electron
excitations , an effective medium theory can be used to describe the
material; however, for the photonic band structure plays an
important role. Special attention is paid to the frequency gap regions in the
latter case.Comment: 12 pages, 7 figure
Half-metallicity and Slater-Pauling behavior in the ferromagnetic Heusler alloys
Introductory chapter for the book "Halfmetallic Alloys - Fundamentals and
Applications" to be published in the series Springer Lecture Notes on Physics,
P. H. Dederichs and I. Galanakis (eds). It contains a review of the theoretical
work on the half-metallic Heusler alloys.Comment: Introductory chapter for the book "Halfmetallic Alloys - Fundamentals
and Applications" to be published in the series Springer Lecture Notes on
Physics, P. H. Dederichs and I. Galanakis (eds
Reptiles as food: Predation of Australian reptiles by introduced red foxes compounds and complements predation by cats
Context: Invasive species are a major cause of biodiversity loss across much of the world, and a key threat to Australiaâs diverse reptile fauna. There has been no previous comprehensive analysis of the potential impact of the introduced European red fox, Vulpes vulpes, on Australian reptiles.
Aims: We seek to provide an inventory of all Australian reptile species known to be consumed by the fox, and identify characteristics of squamate species associated with such predation. We also compare these tallies and characteristics with reptile species known to be consumed by the domestic cat, Felis catus, to examine whether predation by these two introduced species is compounded (i.e. affecting much the same set of species) or complementary (affecting different groups of species).
Methods: We collated records of Australian reptiles consumed by foxes in Australia, with most records deriving from fox dietary studies (tallying >35â000 samples). We modelled presence or absence of fox predation records against a set of biological and other traits, and population trends, for squamate species.
Key results: In total, 108 reptile species (~11% of Australiaâs terrestrial reptile fauna) have been recorded as consumed by foxes, fewer than that reported for cats (263 species). Eighty-six species have been reported to be eaten by both predators. More Australian turtle species have been reported as consumed by foxes than by cats, including many that suffer high levels of predation on egg clutches. Twenty threatened reptile species have been reported as consumed by foxes, and 15 by cats. Squamate species consumed by foxes are more likely to be undergoing population decline than those not known to be consumed by foxes. The likelihood of predation by foxes increased with squamate speciesâ adult body mass, in contrast to the relationship for predation by cats, which peaked at ~217âg. Foxes, but not cats, were also less likely to consume venomous snakes.
Conclusions: The two introduced, and now widespread, predators have both compounding and complementary impacts on the Australian reptile fauna.
Implications: Enhanced and integrated management of the two introduced predators is likely to provide substantial conservation benefits to much of the Australian reptile fauna
Metamaterial/graphene amplitude and frequency modulators for the active control of terahertz quantum cascade lasers
Hybrid metamaterial/graphene amplitude and frequency modulators have been implemented as external optoelectronic mirrors in external cavity configurations with terahertz quantum cascade lasers (QCLs). These devices' tunability is accomplished via the interplay between metamaterial resonant units, normally engineered in mm-size arrays, and graphene. The integration of these devices in external cavity QCLs offers unique emission features and realizes an unprecedented studied regime. The implementation of an external amplitude modulation allows the full switching of laser emission in single mode operation by electrostatically gating graphene. The introduction of more dispersive tunable architectures in frequency modulators yields additionally an all-electronic spectral laser bistability. © 2018 SPIE
Competition between Exceptionally Long-Range Alkyl Sidechain Ordering and Backbone Ordering in Semiconducting Polymers and Its Impact on Electronic and Optoelectronic Properties
Intraâ and intermolecular ordering greatly impacts the electronic and optoelectronic properties of semiconducting polymers. The interrelationship between ordering of alkyl sidechains and conjugated backbones has yet to be fully detailed, despite much prior effort. Here, the discovery of a highly ordered alkyl sidechain phase in six representative semiconducting polymers, determined from distinct spectroscopic and diffraction signatures, is reported. The sidechain ordering exhibits unusually large coherence lengths (â„70 nm), induces torsional/twisting backbone disorder, and results in a vertically multilayered nanostructure with ordered sidechain layers alternating with disordered backbone layers. Calorimetry and in situ variable temperature scattering measurements in a model system poly{4â(5â(4,8âbis(3âbutylnonyl)â6âmethylbenzo[1,2âb:4,5âbâČ]dithiophenâ2âyl)thiophenâ2âyl)â2â(2âbutyloctyl)â5,6âdifluoroâ7â(5âmethylthiophenâ2âyl)â2Hâbenzo[d][1,2,3]triazole} (PBnDTâFTAZ) clearly delineate this competition of ordering that prevents simultaneous longârange order of both moieties. The longârange sidechain ordering can be exploited as a transient state to fabricate PBnDTâFTAZ films with an atypical edgeâon texture and 2.5Ă improved fieldâeffect transistor mobility. The observed influence of ordering between the moieties implies that improved molecular design can produce synergistic rather than destructive ordering effects. Given the large sidechain coherence lengths observed, such synergistic ordering should greatly improve the coherence length of backbone ordering and thereby improve electronic and optoelectronic properties such as charge transport and exciton diffusion lengths
Counting the bodies: Estimating the numbers and spatial variation of Australian reptiles, birds and mammals killed by two invasive mesopredators
Aim
Introduced predators negatively impact biodiversity globally, with insular fauna often most severely affected. Here, we assess spatial variation in the number of terrestrial vertebrates (excluding amphibians) killed by two mammalian mesopredators introduced to Australia, the red fox (Vulpes vulpes) and feral cat (Felis catus). We aim to identify prey groups that suffer especially high rates of predation, and regions where losses to foxes and/or cats are most substantial.
Location
Australia.
Methods
We draw information on the spatial variation in tallies of reptiles, birds and mammals killed by cats in Australia from published studies. We derive tallies for fox predation by (i) modelling continental-scale spatial variation in fox density, (ii) modelling spatial variation in the frequency of occurrence of prey groups in fox diet, (iii) analysing the number of prey individuals within dietary samples and (iv) discounting animals taken as carrion. We derive point estimates of the numbers of individuals killed annually by foxes and by cats and map spatial variation in these tallies.
Results
Foxes kill more reptiles, birds and mammals (peaking at 1071 kmâ2 yearâ1) than cats (55 kmâ2 yearâ1) across most of the unmodified temperate and forested areas of mainland Australia, reflecting the generally higher density of foxes than cats in these environments. However, across most of the continent â mainly the arid central and tropical northern regions (and on most Australian islands) â cats kill more animals than foxes. We estimate that foxes and cats together kill 697 million reptiles annually in Australia, 510 million birds and 1435 million mammals.
Main conclusions
This continental-scale analysis demonstrates that predation by two introduced species takes a substantial and ongoing toll on Australian reptiles, birds and mammals. Continuing population declines and potential extinctions of some of these species threatens to further compound Australia's poor contemporary conservation record
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