Perceptions of Iontophoresis amongst Mississippi Athletic Trainers

Research in the field of modalities is growing quickly, however there is a substantial lack of evidence for the use of iontophoresis, especially in the field of Athletic Training. Due to this, the perceptions of iontophoresis have been impacted amongst clinically practicing athletic trainers. Per this survey, while Mississippi licensed athletic trainers are aware of, and have a general knowledge of how to use iontophoresis, there is a lack of uniformity amongst the parameters and pathologies, consistent with those found in the literature. Of the 37.5 athletic trainers who utilize iontophoresis in their clinical setting, none of them reported using the same parameters. While there was evidence in the free-write questions that the main pathologies treated were musculoskeletal in nature, this by no means narrows down the various ones that these participants treated with iontophoresis. A surprising 88 percent of participants stated that would like to use iontophoresis in their settings, and several participants stated in the final free-write question that they felt more research was necessary to further their knowledge on this modality. Iontophoresis is on the forefront of therapeutic modalities in the field of athletic training, and more research should be completed in order that athletic trainers across the globe may benefit from its many benefits

A Comprehensive Overview of In-patients Treated for Hepatocellular Carcinoma at a Tertiary Care Facility in Tanzania

Hepatocellular carcinoma (HCC) is one of the commonest causes of cancer-related morbidity and mortality worldwide. However, only a limited number of studies on HCC have been conducted in Tanzania. We therefore conducted a cross-sectional study among in-patients treated for HCC in a tertiary referral hospital located in Dar es Salaam, Tanzania, in order to provide a concise description of the clinical characteristics and treatment options offered in the study setting. We identified 36 in-patients treated for HCC over a 6-month data collection period. Seventy-seven percent (n = 28) of the participants were males and about two-thirds (61.2%) were aged between 40 and 60 years. Majority (44.4% [n = 16]) of the patients had Child-Pugh class B and an Eastern Cooperative Oncology Group (ECOG) performance status of 2 (33.3% [n = 12]). Patients with tumors >6.5 cm and multinodular tumors (>3 nodules) accounted for 69.4% (n = 25) and 55.6% (n = 20), respectively. Portal vascular invasion and extrahepatic metastasis were respectively present in 27.8% (n = 10) and 25% (n = 9) of the patients. Of the study participants, only two had early-stage disease as per the Barcelona Clinic Liver Cancer (BCLC) staging system, corresponding to the observed tumor resection rate of 5.6%. The most frequently reported inoperable factor among the study participants was an ECOG performance status > 0 (n = 30 [83.3%]). Findings thus reveal a high proportion of late-stage diseases among participants that could have resulted in the observed low tumor resection rate. Initiatives to facilitate identification of the disease at an early stage are therefore paramount in optimizing care

Mapping out market drivers of improved variety seed use: The case of sorghum in Tanzania

It is understood that the grain market pulls the seed market. The problem of low quality prompted failure of traders and processors to purchase most of the farmers' grain to subsequently drive the use of improved variety seed. The aim of this study is to identify drivers that persuade farmers to use improved variety seeds for grain production. It also assesses factors affecting market participation among small-scale farmers. Descriptive analysis, Binary Logistic model, Probit model and gross margin analysis was conducted from random selected sample of 212 individual farmers, 63 grain off-takers, 3 extension officers and 7 seeds producers through structured interviews. In additional, 80 farmers were interviewed through 10 focus group discussion. The results showed that taste, preferences and price difference between grain and seed were significant and positive drivers that influenced the decision of farmers to use improved varieties at 47% and 0.007%, respectively. Factors such as group membership and farm size were significantly positive affecting farmer's market participation while age was negatively significant affecting farmer's market participation. Gross margin was computed to compare the profit margin between users and non-users of improved variety seeds, where users had high profit margin (530 979.89Tsh/Ha) compared to non-users (472 885.94Tsh/Ha), because non-users incurred high seed cost (54 504.84Tsh/15kg) compared to users of improved variety seeds (39 329.94Tsh/kg). Also, users obtained high grain revenue compared to non-user at 1 353 268.37Tsh and 848 249.11Tsh, respectively. Efforts should be made by value chain actors and other agricultural actors to support farmers based on market demand so they could benefit from high grain quality, quantity and promising grain market

Diversity of Sorghum (Sorghum bicolor L. Moench) Germplasm from Tanzania

Sorghum (Sorghum bicolor L. Moench) is an important cereal crop cultivated in varied agro-ecological zones of Tanzania ranging from the southern highlands to coastal lowlands. Different cultivars and varieties of sorghum are needed for cultivation in such varied zones. Phenotypic properties of Tanzanian sorghums are not well-studied. Objective of this study was to phenotype some sorghum germplasm from Tanzania using morphological markers to establish their diversity for future use in breeding programs. Ninety-eight sorghum genotypes were evaluated at Bumala and Amagoro in Western Kenya during 2009 and 2010 seasons in a randomized complete block design. The International Plant Genetic Resource Centre descriptors of 1993 were used for data collection. Accession MCSR T29 was the earliest which took only 64 days while MCSR T80 was the latest taking 86 days to attain 50% flowering compared to the overall mean of 71 days. The MCSR T71 was the best yielder (114.6 g/ panicle) and MCSR T10 was the lowest (10.3 g/panicle) compared to overall mean of 92.4g/panicle. About 60% of the sorghums had brown and only 2.2% had black grains. MCSR T90 had bold grains with 1000 seed weight of 55.2g. Leaves per plant ranged from 7 in MCSR T69 to 17 in MCSR T25. Plant height ranged from 72.8 cm in MCSR T53 to 434.6 cm in MCSR T80. This study showed that, Tanzanian sorghums are diverse therefore could be used in future breeding programs for developing multipurpose and adapted cultivars. Keywords: Cultivars, Diversity, Phenotype, Varieties, SorghumSorghum (Sorghum bicolor L. Moench) is an important cereal crop cultivated in varied agro-ecological zones of Tanzania ranging from the southern highlands to coastal lowlands. Different cultivars and varieties of sorghum are needed for cultivation in such varied zones. Phenotypic properties of Tanzanian sorghums are not well-studied. Objective of this study was to phenotype some sorghum germplasm from Tanzania using morphological markers to establish their diversity for future use in breeding programs. Ninety-eight sorghum genotypes were evaluated at Bumala and Amagoro in Western Kenya during 2009 and 2010 seasons in a randomized complete block design. The International Plant Genetic Resource Centre descriptors of 1993 were used for data collection. Accession MCSR T29 was the earliest which took only 64 days while MCSR T80 was the latest taking 86 days to attain 50% flowering compared to the overall mean of 71 days. The MCSR T71 was the best yielder (114.6 g/ panicle) and MCSR T10 was the lowest (10.3 g/panicle) compared to overall mean of 92.4g/panicle. About 60% of the sorghums had brown and only 2.2% had black grains. MCSR T90 had bold grains with 1000 seed weight of 55.2g. Leaves per plant ranged from 7 in MCSR T69 to 17 in MCSR T25. Plant height ranged from 72.8 cm in MCSR T53 to 434.6 cm in MCSR T80. This study showed that, Tanzanian sorghums are diverse therefore could be used in future breeding programs for developing multipurpose and adapted cultivars. Keywords: Cultivars, Diversity, Phenotype, Varieties, Sorghu

Superfund: An Assessment of Superfund Site Remedy Selectioin and Implementation

Since its inception in 1980, the U.S. Environmental Protection Agency’s (EPA) Superfund Program has served as the primary mechanism for coordinating the remediation of sites contaminated with hazardous substances. Although the program has successfully overseen cleanup at hundreds of sites, experts have identified a number of weaknesses in the remedy selection and implementation processes. Our study focuses on two weaknesses that have been identified at individual Superfund sites in the previous literature: Remedy Selection: • Selection of non-permanent remedies over permanent remedies Remedy Implementation: • Inconsistency and non-transparency shown in the documentation of cleanup objectives, site cleanup progress, and problems during remedy implementation Although these weaknesses were well documented in previous literature, our group found little evidence that the underlying cause of these weaknesses had been addressed. Our study adds to the current understanding of these weaknesses by investigating their origins using established policy and engineering systems analysis techniques. We have based our analysis on three Superfund site case studies. We offer several recommendations that address the observed weaknesses in site remedy selection and implementation. Lastly, we include suggestions for areas in which further inquiry may be useful

Gut microbiomes and reproductive isolation in Drosophila

Experimental studies of the evolution of reproductive isolation (RI) in real time are a powerful way in which to reveal fundamental, early processes that initiate divergence. In a classic speciation experiment, populations of Drosophila pseudoobscura were subjected to divergent dietary selection and evolved significant positive assortative mating by diet. More recently, a direct role for the gut microbiome in determining this type of RI in Drosophila melanogaster has been proposed. Manipulation of the diet, and hence the gut microbiome, was reported to result in immediate assortative mating by diet, which could be eliminated by reducing gut microbes using antibiotics and recreated by adding back Lactobacillus plantarum. We suggest that the evolutionary significance of this result is unclear. For example, in D. melanogaster, the microbiome is reported as flexible and largely environmentally determined. Therefore, microbiome-mediated RI would be transient and would break down under dietary variation. In the absence of evolutionary coassociation or recurrent exposure between host and microbiome, there are no advantages for the gut bacteria or host in effecting RI. To explore these puzzling effects and their mechanisms further, we repeated the tests for RI associated with diet-specific gut microbiomes in D. melanogaster. Despite observing replicable differences in the gut microbiomes of flies maintained on different diets, we found no evidence for diet-associated RI, for any role of gut bacteria, or for L. plantarum specifically. The results suggest that there is no general role for gut bacteria in driving the evolution of RI in this species and resolve an evolutionary riddle

Heterosis for yield and its components in sorghum (Sorghum bicolor L. Moench) hybrids in dry lands and sub-humid environments of East Africa

A study was conducted in 2011 and 2012 growing seasons to determine levels of heterosis and identify parents for use in sorghum hybrid production in East Africa. A total of 36 pairs of male sterile lines and 42 restorers were obtained from ICRISAT-Nairobi and used for generating 121 experimental hybrids in a line × tester mating design. The hybrids were then evaluated at Kiboko, Ukiriguru and Miwaleni locations in an alpha lattice design with three replications. Each genotype was grown in a 4 m long row at spacing of 60 cm ×50 cm. Phenotypic data were collected as per IPGRI, (1993) descriptors for sorghum on five randomly selected plants. There were significant differences among locations, crosses and male parents for all the characters studied. Female lines were highly significant for all traits except days to 50% flowering (DAF). Desired heterobeltiosis for DAF varied from -5.23 to -14% indicating of early maturing material that can escape terminal drought in rainfed agriculture, characteristic of East African cultivation system. Lowest (desired) heterobeltiosis for plant height was -53.61% with crosses ICSA15×Tegemeo and ATX623×KARI-MTAMA1most promising for this trait. Grain yield showed average heterosis and heterobeltiosis of up to 81.90% and 77.18% respectively both expressed in ICSA11×S35. The parents KARI MTAMA1, IESV91104DL, S35, BTX623, ICSB12 and ICSB11 produced hybrids that yielded high with medium height and maturity therefore could be included to develop hybrid sorghum for East Africa region

Combining ability of some sorghum lines for dry lands and sub-humid environments of East Africa

Sorghum (Sorghum bicolor L. Moench) is a major food crop grown in dry lands and sub-humid areas of East Africa. A study was conducted between 2010 to 2012 in dry lands (Miwaleni, Kiboko) and sub-humid (Ukiriguru) environments to identify parents for hybrid production. It involved 121 lines from ICRISAT and 121 hybrids developed from 36 male sterile lines and 42 restorer lines in a line × tester crossing. Experiments were planted in an alpha lattice design with three replications. Analysis revealed significant (P < 0.05) differences between parents and between crosses for yield and yield components, indicative of potentiality for exploitation. Line IESV23010 expressed best (-6.5) general combing ability (GCA) for days to 50% flowering (DAF). Highest general combiner for height was -55.4 expressed in ICSR24007 and for yield was 382.8 expressed in IESV92156DL. The crosses SDSA4×ICSR43 and SDSA4×ICSR59059 exhibited high and significant specific combining ability (SCA) for DAF. Lines IESB2 and ICSB44 were suited to sub-humid, whereas BTX623, ICSB15 and ICSB6 to dry lands environments. Testers IESV91104DL, IESV91131DL, ICSR93034 were well suited to dry lands whereas KARI-MTAMA1 and IESV23019 to sub-humid environments. The parents identified could be used to produce hybrids and varieties for the dry lands and sub-humid environments

European Sea Bass (Dicentrarchus labrax) immune status and disease resistance are impaired by arginine dietary supplementation

Infectious diseases and fish feeds management are probably the major expenses in the aquaculture business. Hence, it is a priority to define sustainable strategies which simultaneously avoid therapeutic procedures and reinforce fish immunity. Currently, one preferred approach is the use of immunostimulants which can be supplemented to the fish diets. Arginine is a versatile amino acid with important mechanisms closely related to the immune response. Aiming at finding out how arginine affects the innate immune status or improve disease resistance of European seabass (Dicentrarchus labrax) against vibriosis, fish were fed two arginine-supplemented diets (1% and 2% arginine supplementation). A third diet meeting arginine requirement level for seabass served as control diet. Following 15 or 29 days of feeding, fish were sampled for blood, spleen and gut to assess cell-mediated immune parameters and immune-related gene expression. At the same time, fish from each dietary group were challenged against Vibrio anguillarum and survival was monitored. Cell-mediated immune parameters such as the extracellular superoxide and nitric oxide decreased in fish fed arginine-supplemented diets. Interleukins and immune-cell marker transcripts were down-regulated by the highest supplementation level. Disease resistance data were in accordance with a generally depressed immune status, with increased susceptibility to vibriosis in fish fed arginine supplemented diets. Altogether, these results suggest a general inhibitory effect of arginine on the immune defences and disease resistance of European seabass. Still, further research will certainly clarify arginine immunomodulation pathways thereby allowing the validation of its potential as a prophylactic strategy.European Union's Seventh Framework Programme AQUAEXCEL (Aquaculture Infrastructures for Excellence in European Fish Research) [262336]; AQUAIMPROV [NORTE-07-0124-FEDER-000038]; North Portugal Regional Operational Programme (ON. 2 - O Novo Norte) , under the National Strategic Reference Framework, through the European Regional Development Fund; North Portugal Regional Operational Programme (ON. 2 - O Novo Norte), under the National Strategic Reference Framework through the COMPETE - Operational Competitiveness Programme; Fundacao para a Ciencia e Tecnologia; Fundacao para a Ciencia e Tecnologia [SFRH/BD/89457/2012, SFRH/BPD/77210/2011]; Generalitat Valenciana through the project REVIDPAQUA [ISIC/2012/003]; [PEst-C/MAR/LA0015/2013]; [UID/Multi/04423/2013]info:eu-repo/semantics/publishedVersio