417 research outputs found
Infrastructural Speculations: Tactics for Designing and Interrogating Lifeworlds
This paper introduces “infrastructural speculations,” an orientation toward speculative design that considers the complex and long-lived relationships of technologies with broader systems, beyond moments of immediate invention and design. As modes of speculation are increasingly used to interrogate questions of broad societal concern, it is pertinent to develop an orientation that foregrounds the “lifeworld” of artifacts—the social, perceptual, and political environment in which they exist. While speculative designs often imply a lifeworld, infrastructural speculations place lifeworlds at the center of design concern, calling attention to the cultural, regulatory, environmental, and repair conditions that enable and surround particular future visions. By articulating connections and affinities between speculative design and infrastructure studies research, we contribute a set of design tactics for producing infrastructural speculations. These tactics help design researchers interrogate the complex and ongoing entanglements among technologies, institutions, practices, and systems of power when gauging the stakes of alternate lifeworlds
A prospective cohort study comparing the reactogenicity of trivalent influenza vaccine in pregnant and non-pregnant women
Background: Influenza vaccination during pregnancy can prevent serious illness in expectant mothers and provide protection to newborns; however, historically uptake has been limited due to a number of factors, including safety concerns. Symptomatic complaints are common during pregnancy and may be mistakenly associated with reactions to trivalent influenza vaccine (TIV). To investigate this, we compared post-vaccination events self-reported by pregnant women to events reported by non-pregnant women receiving TIV.
Methods: A prospective cohort of 1,086 pregnant women and 314 non-pregnant female healthcare workers (HCWs) who received TIV between March-May 2014 were followed-up seven days post-vaccination to assess local and systemic adverse events following immunisation (AEFIs). Women were surveyed by text message regarding perceived reactions to TIV. Those reporting an AEFI completed an interview by telephone or mobile phone to ascertain details. Logistic regression models adjusting for age and residence were used to compare reactions reported by pregnant women and non-pregnant HCWs.
Results: Similar proportions of pregnant women and non-pregnant, female HCWs reported ≥1 reaction following vaccination with TIV (13.0% and 17.3%, respectively; OR = 1.2 [95% CI: 0.8-1.8]). Non-pregnant, female HCWs were more likely to report fever or headache compared to pregnant women (OR: 4.6 [95% CI 2.1-10.3] and OR: 2.2 [95% CI 1.0-4.6], respectively). No other significant differences in reported symptoms were observed. No serious vaccine-associated adverse events were reported, and less than 2% of each group sought medical advice for a reaction.
Conclusions: We found no evidence suggesting pregnant women are more likely to report adverse events following influenza vaccination when compared to non-pregnant female HCWs of similar age, and in some cases, pregnant women reported significantly fewer adverse events. These results further support the safety of TIV administered in pregnant women
Two More Candidate AM Canum Venaticorum (AM CVn) Binaries from the Sloan Digital Sky Survey
AM CVn systems are a select group of ultracompact binaries with the shortest
orbital periods of any known binary subclass; mass-transfer is likely from a
low-mass (partially-)degenerate secondary onto a white dwarf primary, driven by
gravitational radiation. In the past few years, the Sloan Digital Sky Survey
(SDSS) has provided five new AM CVns. Here we report on two further candidates
selected from more recent SDSS data. SDSS J1208+3550 is similar to the earlier
SDSS discoveries, recognized as an AM CVn via its distinctive spectrum which is
dominated by helium emission. From the expanded SDSS Data Release 6 (DR6)
spectroscopic area, we provide an updated surface density estimate for such AM
CVns of order 10^{-3.1} to 10^{-2.5} per deg^2 for 15<g<20.5. In addition, we
present another new candidate AM CVn, SDSS J2047+0008, that was discovered in
the course of followup of SDSS-II supernova candidates. It shows nova-like
outbursts in multi-epoch imaging data; in contrast to the other SDSS AM CVn
discoveries, its (outburst) spectrum is dominated by helium absorption lines,
reminiscent of KL Dra and 2003aw. The variability selection of SDSS J2047+0008
from the 300 deg^2 of SDSS Stripe 82 presages further AM CVn discoveries in
future deep, multicolor, and time-domain surveys such as LSST. The new
additions bring the total SDSS yield to seven AM CVns thus far, a substantial
contribution to this rare subclass, versus the dozen previously known.Comment: 19 pages, 5 figures, 1 table; submitted to A
Peculiar Type II Supernovae from Blue Supergiants
The vast majority of Type II supernovae (SNe) are produced by red supergiants
(RSGs), but SN 1987A revealed that blue supergiants (BSGs) can produce members
of this class as well, albeit with some peculiar properties. This best studied
event revolutionized our understanding of SNe, and linking it to the bulk of
Type II events is essential. We present here optical photometry and
spectroscopy gathered for SN 2000cb, which is clearly not a standard Type II SN
and yet is not a SN 1987A analog. The light curve of SN 2000cb is reminiscent
of that of SN 1987A in shape, with a slow rise to a late optical peak, but on
substantially different time scales. Spectroscopically, SN 2000cb resembles a
normal SN II but with ejecta velocities that far exceed those measured for SN
1987A or normal SNe II, above 18000 km/s for H-alpha at early times. The red
colours, high velocities, late photometric peak, and our modeling of this
object all point toward a scenario involving the high-energy explosion of a
small-radius star, most likely a BSG, producing 0.1 solar masses of Ni-56.
Adding a similar object to the sample, SN 2005ci, we derive a rate of about 2%
of the core-collapse rate for this loosely defined class of BSG explosions.Comment: Accepted to MNRAS on March 14, 201
Survey of Period Variations of Superhumps in SU UMa-Type Dwarf Novae. II: The Second Year (2009-2010)
As an extension of the project in Kato et al. (2009, arXiv:0905.1757), we
collected times of superhump maxima for 61 SU UMa-type dwarf novae mainly
observed during the 2009-2010 season. The newly obtained data confirmed the
basic findings reported in Kato et al. (2009): the presence of stages A-C, as
well as the predominance of positive period derivatives during stage B in
systems with superhump periods shorter than 0.07 d. There was a systematic
difference in period derivatives for systems with superhump periods longer than
0.075 d between this study and Kato et al. (2009). We suggest that this
difference is possibly caused by the relative lack of frequently outbursting SU
UMa-type dwarf novae in this period regime in the present study. We recorded a
strong beat phenomenon during the 2009 superoutburst of IY UMa. The close
correlation between the beat period and superhump period suggests that the
changing angular velocity of the apsidal motion of the elliptical disk is
responsible for the variation of superhump periods. We also described three new
WZ Sge-type objects with established early superhumps and one with likely early
superhumps. We also suggest that two systems, VX For and EL UMa, are WZ
Sge-type dwarf novae with multiple rebrightenings. The O-C variation in OT
J213806.6+261957 suggests that the frequent absence of rebrightenings in very
short-Porb objects can be a result of sustained superoutburst plateau at the
epoch when usual SU UMa-type dwarf novae return to quiescence preceding a
rebrightening. We also present a formulation for a variety of Bayesian
extension to traditional period analyses.Comment: 63 pages, 77 figures, 1 appendix, Accepted for publication in PASJ,
data correctio
The Sloan Digital Sky Survey-II Supernova Survey: Search Algorithm and Follow-up Observations
The Sloan Digital Sky Survey-II Supernova Survey has identified a large
number of new transient sources in a 300 sq. deg. region along the celestial
equator during its first two seasons of a three-season campaign. Multi-band
(ugriz) light curves were measured for most of the sources, which include solar
system objects, Galactic variable stars, active galactic nuclei, supernovae
(SNe), and other astronomical transients. The imaging survey is augmented by an
extensive spectroscopic follow-up program to identify SNe, measure their
redshifts, and study the physical conditions of the explosions and their
environment through spectroscopic diagnostics. During the survey, light curves
are rapidly evaluated to provide an initial photometric type of the SNe, and a
selected sample of sources are targeted for spectroscopic observations. In the
first two seasons, 476 sources were selected for spectroscopic observations, of
which 403 were identified as SNe. For the Type Ia SNe, the main driver for the
Survey, our photometric typing and targeting efficiency is 90%. Only 6% of the
photometric SN Ia candidates were spectroscopically classified as non-SN Ia
instead, and the remaining 4% resulted in low signal-to-noise, unclassified
spectra. This paper describes the search algorithm and the software, and the
real-time processing of the SDSS imaging data. We also present the details of
the supernova candidate selection procedures and strategies for follow-up
spectroscopic and imaging observations of the discovered sources.Comment: Accepted for publication in The Astronomical Journal (66 pages, 13
figures); typos correcte
Efficacy of a trivalent influenza vaccine against seasonal strains and against 2009 pandemic H1N1: a randomized, placebo-controlled trial
Background: Before pandemic H1N1 vaccines were available, the potential benefit of existing seasonal trivalent inactivated influenza vaccines (IIV3s) against influenza due to the 2009 pandemic H1N1 influenza strain was investigated, with conflicting results. This study assessed the efficacy of seasonal IIV3s against influenza due to 2008 and 2009 seasonal influenza strains and against the 2009 pandemic H1N1 strain.
Methods: This observer-blind, randomized, placebo-controlled study enrolled adults aged 18–64 years during 2008 and 2009 in Australia and New Zealand. Participants were randomized 2:1 to receive IIV3 or placebo. The primary objective was to demonstrate the efficacy of IIV3 against laboratory-confirmed influenza. Participants reporting an influenza-like illness during the period from 14 days after vaccination until 30 November of each study year were tested for influenza by real-time reverse transcription polymerase chain reaction.
Results: Over a study period of 2 years, 15,044 participants were enrolled (mean age ± standard deviation: 35.5 ± 14.7 years; 54.4% female). Vaccine efficacy of the 2008 and 2009 IIV3s against influenza due to any strain was 42% (95% confidence interval [CI]: 30%, 52%), whereas vaccine efficacy against influenza due to the vaccine-matched strains was 60% (95% CI: 44%, 72%). Vaccine efficacy of the 2009 IIV3 against influenza due to the 2009 pandemic H1N1 strain was 38% (95% CI: 19%, 53%). No vaccine-related deaths or serious adverse events were reported. Solicited local and systemic adverse events were more frequent in IIV3 recipients than placebo recipients (local: IIV3 74.6% vs placebo 20.4%, p < 0.001; systemic: IIV3 46.6% vs placebo 39.1%, p < 0.001).
Conclusions: The 2008 and 2009 IIV3s were efficacious against influenza due to seasonal influenza strains and the 2009 IIV3 demonstrated moderate efficacy against influenza due to the 2009 pandemic H1N1 strain
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