Creación de una empresa productora y exportadora de aceite de aguacate Hass

The following business plan analyzes the feasibility of creating an enterprise that produces Hass avocado oil and commercializes it into the French market. This project is closely related to the necessary change of the productive matrix of the country that leads to its transformation from being a raw material supplier to an international exporter of high quality processed goods with added value. In addition, growing consumer trends of healthy products appear as an interesting opportunity for new brands that promote both body and health care. Avocado oil consumers’ number increase because of its exquisite taste and its versatility compared to other oils. Its main ingredient: the avocado is known for the numerous benefits that are received when consumed in a regular basis, specifically the variety Hass. The growing demand of healthy products and these trends create a market opportunity that should be taken by agricultural countries that have geographical or quality advantages for the production, as is the case of Ecuador.El siguiente plan de negocios analiza la factibilidad de crear una empresa productora y exportadora de aceite de aguacate Hass con el fin de comercializarlo en un principio en el mercado de Francia. Este proyecto está estrechamente relacionado con el cambio indispensable de la matriz productiva del país y su transformación de ser un país proveedor de materia prima a ser un exportador internacional de bienes elaborados con valor agregado y totalmente competitivo. Además, las crecientes tendencias de consumo de productos saludables abren una puerta a nuevas marcas que promuevan el bienestar, el cuidado del cuerpo y la salud. Así el aceite de aguacate gana adeptos a nivel mundial por su exquisito sabor y versatilidad frente a otros aceites comestibles. Su ingrediente principal: el aguacate es conocido por los numerosos beneficios que se presentan al consumirlo de forma regular, especialmente la variedad Hass. La creciente demanda este producto crea una oportunidad de mercado que debe ser aprovechada por países agrícolas que presentan ventajas para la producción ya sea de tipo geográfico o por la calidad de su producto, como es el caso de Ecuador

Inobservancia de los límites establecidos a la jornada atípica de los trabajadores mineros en la legislación peruana

La investigación tiene como objeto el estudio de la adecuada aplicación del régimen atípico en el sector minero puesto que se aprecia que las empresas mineras mediante sus titulares y/o representantes abusan de su calidad de empleadores, siendo necesario para ello regular una ley que limite dicho abuso de poder, tal cual se aprecia en los datos estadísticos señalados por el INEI, los mismos que se apreciarán bajo el desarrollo de la presente investigación, demostrándose así que mediante la creación de dicha ley se elimine la inobservancia de los límites señalados en el artículo Reglamento 9° del TUO de la Ley de Jornada de Trabajo, Horario y Trabajo en Sobretiempo - Decreto Supremo Nº 008-2002-TR, que prescribe “(…) el promedio de horas trabajadas en el ciclo o período correspondiente no podrá exceder los límites máximos previstos por la Ley (…), generando una correcta y justa aplicación del régimen laboral atípico en el sector minero.The purpose of the research is to study the appropriate application of the atypical regime in the mining sector since it is observed that mining companies through their owners and / or representatives abuse their status as employers, being necessary to regulate a law that limits said abuse of power, as shown in the statistical data indicated by the INEI, which will be appreciated under the development of the present investigation, thus demonstrating that by means of the creation of said law the non-observance of the limits indicated in the article is eliminated Regulation 9 of the TUO of the Law on Working Hours, Hours and Work in Overtime - Supreme Decree No. 008-2002-TR, which prescribes ""(...) the average hours worked in the corresponding cycle or period may not exceed the limits maximums foreseen by the Law (...), generating a correct and fair application of the atypical labor regime in the mining sector.Tesi

Diseño y Medición de los Parámetros de una Antena Fractal basada em la Curva de Koch para la Recepción de Señales TDT em la Banda UHF

Purpose ”“ In this research paper, the electrical and radiation characteristics of a proposed fractal antenna based on the Koch curve in the second iteration for reception of digital terrestrial television signals are designed and analyzed by laboratory tests. Methodology/approach/design ”“ The design is based on the concepts of fractal geometry and on a previously designed antenna, which is adapted to obtain a different frequency of operation; the designed antenna is constructed in three different ways, finally, they are tested in the lab using vector-network-analyzer, that allows to measure parameters, such as: VSWR, gain and radiation pattern. Findings ”“ The fractal antenna based on the Koch curve has the necessary characteristics to receive digital terrestrial television signals in the UHF band.Propósito ”“ En este artículo de investigación se diseña y analiza mediante pruebas de laboratorio las características eléctricas y de radiación de una antena fractal basada en la curva de Koch en la segunda iteración para la recepción de señales de televisión digital terrestre. Metodología ”“ El diseño se basa en los conceptos de la  geometría fractal y se parte de una antena diseñada previamente, que se adapta para obtener una frecuencia de operación diferente a la original; la antena diseñada se construye de tres maneras diferentes, para finalmente realizar pruebas de laboratorio usando un analizador vectorial de redes que permite medir parámetros, como: VSWR, ganancia y lóbulos de radiación. Resultados ”“ Se comprobó que la antena fractal basada en la curva de Koch, tiene las características necesarias para recibir señales de televisión digital terrestre en la banda UHF.Propósito ”“ En este artículo de investigación se diseña y analiza mediante pruebas de laboratorio las características eléctricas y de radiación de una antena fractal basada en la curva de Koch en la segunda iteración para la recepción de señales de televisión digital terrestre. Metodología ”“ El diseño se basa en los conceptos de la  geometría fractal y se parte de una antena diseñada previamente, que se adapta para obtener una frecuencia de operación diferente a la original; la antena diseñada se construye de tres maneras diferentes, para finalmente realizar pruebas de laboratorio usando un analizador vectorial de redes que permite medir parámetros, como: VSWR, ganancia y lóbulos de radiación. Resultados ”“ Se comprobó que la antena fractal basada en la curva de Koch, tiene las características necesarias para recibir señales de televisión digital terrestre en la banda UHF

La hegemonía en cuestión: por una teoría del valor alternativa

En este artículo cuestionamos la ortodoxia de la teoría del valor frente a posibles alternativas. Hay una teoría económica dominante a través de la cual se nos presenta un mundo sujeto a leyes económicas incuestionables: la teoría neoclásica. Se hace necesaria una teoría del valor alternativa que permita dar cuenta de los mecanismos que posibilitan la coordinación de agentes descentralizados. Presentamos dos posturas frente a las teorías del valor alternativas que nos abren caminos para responder a la cuestión de la coordinación en una sociedad capitalista

EDUCACIÓN Y GESTIÓN NUTRICIONAL EN HOMBRES ADULTOS MAYORES. CASO DE ESTUDIO

Las personas que llegan a una cierta edad se enfrentan a problemas físicos, psíquicos y sociales que provienen de cambios biológicos propios de la edad, estando necesitadas de atención sistemática, particularmente en su educación y gestión nutricional. El objetivo del presente artículo es caracterizar la educación y gestión nutricional en los pacientes hombres mayores de 60 años del Consultorio Médico # 2 del Policlínico “Carlos Verdugo”, en Matanzas, Cuba. Fue una investigación cuanti-cualitativa, de tipo observacional, transversal, y ambispectiva, desarrollada en una población de 39 hombres, a los que se les aplicó una entrevista de 9 preguntas y se les efectuó un Diagnóstico de Necesidades de Aprendizaje. Se obtuvo como resultados que la población objeto de estudio es relativamente joven (69 años) dentro de este grupo etáreo; en ella predomina el acompañamiento conyugal; presenta problemas de salud, fundamentalmente enfermedades crónicas, dentro de ellas la hipertensión arterial y el sobrepeso u obesidad.Entre sus principales debilidades se encuentran sus enfermedades crónicas;su bajo ingreso familiar; su ineficiente gestión salarial; la escasez de medios de transporte y el poco aprovechamiento en materia nutricional de autoridades de la comunidad

Clinical characterization and outcomes of 85 patients with neurosarcoidosis

To analyze the frequency and clinical phenotype of neurosarcoidosis (NS) in one of the largest nationwide cohorts of patients with sarcoidosis reported from southern Europe. NS was evaluated according to the Diagnostic Criteria for Central Nervous System and Peripheral Nervous System Sarcoidosis recently proposed by Stern et al. Pathologic confrmation of granulomatous disease was used to subclassify NS into defnite (confrmation in neurological tissue), probable (confrmation in extraneurological tissue) and possible (no histopathological confrmation of the disease). Of the 1532 patients included in the cohort, 85 (5.5%) fulflled the Stern criteria for NS (49 women, mean age at diagnosis of NS of 47.6 years, 91% White). These patients developed 103 neurological conditions involving the brain (38%), cranial nerves (36%), the meninges (3%), the spinal cord (10%) and the peripheral nerves (14%); no patient had concomitant central and peripheral nerve involvements. In 59 (69%) patients, neurological involvement preceded or was present at the time of diagnosis of the disease. According to the classifcation proposed by Stern et al., 11 (13%) were classifed as a defnite NS, 61 (72%) as a probable NS and the remaining 13 (15%) as a possible NS. In comparison with the systemic phenotype of patients without NS, patients with CNS involvement presented a lower frequency of thoracic involvement (82% vs 93%, q= 0.018), a higher frequency of ocular (27% vs 10%, q< 0.001) and salivary gland (15% vs 4%, q= 0.002) WASOG involvements. In contrast, patients with PNS involvement showed a higher frequency of liver involvement (36% vs 12%, p= 0.02) in comparison with patients without NS. Neurosarcoidosis was identifed in 5.5% of patients. CNS involvement prevails signifcantly over PNS involvement, and both conditions do not overlap in any patient. The systemic phenotype associated to each involvement was clearly diferentiated, and can be helpful not only in the early identifcation of neurological involvement, but also in the systemic evaluation of patients diagnosed with neurosarcoidosis

Post-Mortem diagnosis of dementia by informant interview.

The diagnosis of normal cognition or dementia in the Brazilian Brain Bank of the Aging Brain Study Group (BBBABSG) has relied on postmortem interview with an informant. Objectives:To ascertain the sensitivity and specificity of postmortem diagnosis based on informant interview compared against the diagnosis established at a memory clinic. Methods:A prospective study was conducted at the BBBABSG and at the Reference Center for Cognitive Disorders (RCCD), a specialized memory clinic of the Hospital das Clínicas, University of São Paulo Medical School. Control subjects and cognitively impaired subjects were referred from the Hospital das Clínicas to the RCCD where subjects and their informants were assessed. The same informant was then interviewed at the BBBABSG. Specialists' panel consensus, in each group, determined the final diagnosis of the case, blind to other center's diagnosis. Data was compared for frequency of diagnostic equivalence. For this study, the diagnosis established at the RCCD was accepted as the gold standard. Sensitivity and specificity were computed. Results:Ninety individuals were included, 45 with dementia and 45 without dementia (26 cognitively normal and 19 cognitively impaired but non-demented). The informant interview at the BBBABSG had a sensitivity of 86.6% and specificity of 84.4% for the diagnosis of dementia, and a sensitivity of 65.3% and specificity of 93.7% for the diagnosis of normal cognition. Conclusions:The informant interview used at the BBBABSG has a high specificity and sensitivity for the diagnosis of dementia as well as a high specificity for the diagnosis of normal cognition

Association of APOA5 and APOC3 genetic polymorphisms with severity of hypertriglyceridemia in patients with cutaneous T-Cell lymphoma treated with bexarotene

Importance: hypertriglyceridemia is the most frequent and limiting adverse effect of bexarotene therapy in cutaneous T-cell lymphoma (CTCL). Despite standard prophylactic measures, there is a wide variability in the severity of this complication, which could be associated with both genetic and environmental factors. Objectives: to analyze the association between genetic polymorphisms of apolipoprotein genes APOA5, APOC3, and APOE and the severity of hypertriglyceridemia during bexarotene therapy and to optimize patient selection for bexarotene therapy based on adverse effect profile. Design, Setting, and Participants: this case series study was conducted in 12 university referral hospitals in Spain from September 17, 2014, to February 6, 2015. One hundred twenty-five patients with a confirmed diagnosis of CTCL who had received bexarotene therapy for at least 3 months were enrolled. Nine patients were excluded owing to missing analytic triglyceride level data, leaving a study group of 116 patients. Data on demographic and cardiovascular risk factor were collected, and a complete blood analysis, including lipid profile and genetic analysis from a saliva sample, was performed. Main Outcomes and Measures: primary outcomes were the maximal triglyceride levels reported in association with the minor alleles of the polymorphisms studied. Results: among 116 patients, the mean (SD) age was 61.2 (14.7) years, 69 (59.5%) were men, and 85 (73.2%) had mycosis fungoides, the most prevalent form of CTCL. During bexarotene therapy, 96 patients (82.7%) experienced hypertriglyceridemia, which was severe or extreme in 8 of these patients (8.3%). Patients who carried minor alleles of the polymorphisms did not show significant differences in baseline triglyceride concentrations. After bexarotene treatment, carriers of at least 1 of the 2 minor alleles of APOA5 c.-1131T>C and APOC3 c.*40C>G showed lower levels of triglycerides than noncarriers (mean [SD], 241.59 [169.91] vs 330.97 [169.03] mg/dL, respectively; P = .02). Conclusions and Relevance: these results indicate that the screening of APOA5 and APOC3 genotypes may be useful to estimate changes in triglyceride concentrations during bexarotene treatment in patients with CTCL and also to identify the best candidates for bexarotene therapy based on the expected adverse effect profile