Tomographic Simulations of Accretion Disks in Cataclysmic Variables - Flickering and Wind

Both continuum and emission line flickering are phenomena directly associated with the mass accretion process. In this work we simulate accretion disk Doppler maps including the effects of winds and flickering flares. Synthetic flickering Doppler maps are calculated and the effect of the flickering parameters on the maps is explored. Jets and winds occur in many astrophysical objects where accretion disks are present. Jets are generally absent among the cataclysmic variables (CVs), but there is evidence of mass loss by wind in many objects. CVs are ideal objects to study accretion disks and consequently to study the wind associated with these disks. We also present simulations of accretion disks including the presence of a wind with orbital phase resolution. Synthetic H-alpha line profiles in the optical region are obtained and their corresponding Doppler maps are calculated. The effect of the wind simulation parameters on the wind line profiles is also explored. From this study we verified that optically thick lines and/or emission by diffuse material into the primary Roche lobe are necessary to generate single peaked line profiles, often seen in CVs. The future accounting of these effects is suggested for interpreting Doppler tomography reconstructions.Comment: 9 pages, 9 figure

A FILOSOFIA DA CIÊNCIA E A FILOSOFIA DA QUÍMICA: UMA PERSPECTIVA CONTEMPORÂNEA

Este trabalho tem por objetivo identificar e caracterizar o atual estado da relação entre a filosofia da ciência contemporânea e a filosofia da química. Trata-se deuma abordagem qualitativa, constituindo-se de um estudo exploratório do tipo estado da arte. Inicialmente, refletimos sobre algumas razões que culminaram no histórico negligenciamento da filosofia da química pela filosofia da ciência. Em seguida, a partir de uma breve caracterização desta relação, argumentamos que algumas dimensões, como o complexo estilo de pensamento e fazer químico, devem ser apropriadas pela filosofia da ciência. Por fim, defendemos a necessidade de maior inserção das filosofias da química e da ciência, no âmbito da formação deprofessores de química

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362