Relação entre adiposidade visceral e hipertensão arterial sistêmica

Objective: to evaluate the relationship between abdominal circumference (AC) and blood pressure in men of a municipality from Parana state. Method: case-control study in which men were evaluated for use of antihypertensive, age, weight, height, and CA, through a questionnaire and measurements of anthropometric indices, respectively. Data were analyzed using the odds ratio. Results: men over 60, obese and with high AC are more susceptible to developing hypertension. AC was the risk factor with the highest statistical association. Conclusions: fat deposits in the abdominal region represent an important risk factor for the development of hypertension and anthropometric indices should be applied periodically in patients prone to hypertensionObjetivos: evaluar la relación entre la circunferencia de la cintura (CC) y la presión arterial en hombres de un municipio Paranaense. Método: estudio del tipo caso-controle en lo cual hombres fueron evaluados para el uso de antihipertensivos, edad, peso, altura y medida de la CC, a través de aplicación de cuestionario y medidas de los índices antropométricos, respectivamente. Los datos fueron analizados por medio del odds ratio. Resultados: hombres mayores de 60 años, obesos y con elevación de CC son más susceptibles a desarrollar hipertensión arterial. La CC fue el factor de riesgo de mayor asociación estadística. Conclusiones: depósitos de grasa en la región abdominal representan un factor de riesgo importante para el desarrollo de la hipertensión arterial y los índices antropométricos se deben aplicar periódicamente en pacientes propensos a la hipertensión.Objetivos: avaliar a relação entre a circunferência abdominal (CA) e a pressão arterial em homens de um município Paranaense. Métodos: estudo do tipo caso-controle, no qual homens foram avaliados quanto ao uso de anti-hipertensivo, idade, peso, altura e medida da CA, por meio de aplicação de questionário e medidas dos índices antropométricos, respectivamente. Os dados foram analisados por meio do odds ratio. Resultados: homens acima dos 60 anos, obesos e com CA elevada estão mais expostos a desenvolver hipertensão arterial. A CA foi o fator de risco com maior associação estatística. Conclusões: depósitos de gordura na região abdominal representam importante fator de risco para o desenvolvimento da hipertensão arterial e os índices antropométricos deveriam ser aplicados periodicamente em pacientes com propensão à hipertensão

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Dengue antibodies in blood donors Pesquisa de anticorpos antidengue em doadores de sangue

BACKGROUND: Dengue is an urban arbovirus whose etiologic agent is a virus of the genus Flavorius with four distinct antigen serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) that is transmitted to humans through the bite of the mosquito Aedes aegypti. The Campo Mourão region in Brazil is endemic for dengue fever. OBTECTIVE: The aim of this study was to evaluate the presence of IgG and IgM antibodies specific to the four serotypes of dengue in donors of the blood donor service in the city of Campo Mourão. METHODS: Epidemiological records were evaluated and 4 mL of peripheral blood from 213 blood donors were collected in tubes without anticoagulant. Serum was then obtained and immunochromatographic tests were undertaken (Imuno-Rápido Dengue IgM/IgG TM). Individuals involved in the study answered a social and epidemiological questionnaire on data which included age, gender and diagnosis of dengue. RESULTS: Only three (1.4%) of the 213 blood tests were positive for IgG anti-dengue antibodies. No donors with IgM antibody, which identifies acute infection, were identified. CONCLUSIONS: The results of the current analysis show that the introduction of quantitative or molecular serological methods to determine the presence of anti-dengue antibodies or the detection of the dengue virus in blood donors in endemic regions should be established so that the quality of blood transfusions is guaranteed.<br>OBJETIVO: O objetivo desta pesquisa foi realizar uma triagem sorológica para detectar a presença de anticorpos IgG e IgM específicos para os quatro sorotipos da dengue em doadores de sangue atendidos pelo Hemonúcleo de Campo Mourão-PR. MÉTODOS: foram aplicadas fichas epidemiológicas e coletados 4 mL de sangue periférico em tubos sem anticoagulante de 213 doadores de sangue. Posteriormente, foi obtido o soro e realizado o teste imunocromatrográfico (Imuno - Rápido Dengue IgM/IgG). Os indivíduos envolvidos neste estudo responderam um questionário sócioepidemiológico, incluindo informações referentes à caracterização dos participantes, como idade, gênero, diagnóstico prévio de dengue, entre outros. RESULTADOS: Das 213 amostras testadas, três (1,4%) apresentaram resultados positivos na pesquisa de anticorpos IgG contra o vírus da dengue. Em relação à infecção aguda do vírus da dengue, não houve presença de anticorpos IgM nos doadores de sangue, evidenciando assim que as amostras biológicas analisadas não apresentavam riscos à saúde do receptor. CONCLUSÃO: Acredita-se que a introdução de métodos sorológicos e moleculares para determinar a presença de anticorpos antidengue e/ou detecção do vírus da dengue em doadores de sangue em regiões endêmicas deveriam ser implantados a fim de assegurar a qualidade da transfusão sanguínea

Presence of anti-Leishmania (Viannia) braziliensis antibodies in blood donors in the West-Central region of the State of Paraná, Brazil

ABSTRACTINTRODUCTION:Serological screening in blood banks does not include all transmittable diseases. American cutaneous leishmaniasis (ACL) has a high detection rate in the municipalities of the State of Paraná.METHODS:This study analyzed the presence of anti- Leishmania braziliensisantibodies in 176 blood donors who live in these endemic areas. The variables were analyzed with the &#967;2 test and Stata 9.1 software. RESULTS: Twenty (11.4%) samples were positive for the presence of anti- L. braziliensisantibodies. CONCLUSIONS: The high percentage of donors with anti- Leishmania spp. antibodies indicates the need to study the risk of ACL transmission through blood donors