Antropoestratigrafía: nuevas unidades litológicas del Cuaternario controladas por la actividad humana

Many areas around the world such as the Mediterranean region have been inhabited without interruption for thousands of years. This is the case of the city of Barcelona (Spain), where remains of human settlements dating from pre-Roman times until the present have been found. A detailed geological mapping of the area occupied by the city of Barcelona raises a number of questions about the Holocene stratigraphy affected by human activity. In the old urban and surrounding areas most of the sedimentary deposits accumulated during settlement result from human interactions. Thus, new anthropostratigraphic units are proposed. The sedimentary deposits and the infill of rock excavations due to human presence may be divided into three categories: Natural lithoanthropogenic units (NAU) when their formation is not directly affected by anthropogenic activity but these contain artefacts of human origin. Induced lithoanthropogenic units (IAU) when natural processes together with human actions produce sedimentation or erosion due to natural phenomena; Constructed lithoanthropogenic units (CAU) when sedimentary accumulations and sharp contacts result from direct human activity.A lo largo de todo el globo terrestre, existen muchas zonas como la región mediterránea que han sido habitadas ininterrumpidamente durante miles de años. Este es el caso de la ciudad de Barcelona donde se han encontrado restos de asentamientos humanos desde los tiempos pre-romanos hasta la actualidad. Un mapa geológico detallado de la zona ocupada por la ciudad de Barcelona plantea una serie de interrogantes sobre la estratigrafía del Holoceno influenciado por la actividad humana. En la zona urbana antigua y en áreas circundantes, la mayoría de los depósitos acumulados durante el asentamiento se han producido por las interacciones humanas. Por tanto, se proponen nuevas unidades antropoestratigráficas. Los depósitos sedimentarios así como los rellenos de lasexcavaciones debidos a la presencia humana pueden ser divididos en tres categorías: Unidades litoantropogénicas naturales (NAU) cuando su generación no ha sido afectada directamente por la actividad humana, pero contienen diversos artefactos artificiales. Unidades litoantropogénicas inducidas (IAU) cuando los procesos naturales junto a las acciones humanas producen sedimentación o erosión debido a los fenómenos naturales. Unidades litoantropogénicas construidas (CAU) cuando las acumulaciones sedimentarias y los contactos nítidos son el resultado de la actividad humana directa

Table Detection in Invoice Documents by Graph Neural Networks

This is the author accepted manuscript. The final version is available from IEEE via the DOI in this record.Tabular structures in documents offer a complementary dimension to the raw textual data, representing logical or quantitative relationships among pieces of information. In digital mail room applications, where a large amount of administrative documents must be processed with reasonable accuracy, the detection and interpretation of tables is crucial. Table recognition has gained interest in document image analysis, in particular in unconstrained formats (absence of rule lines, unknown information of rows and columns). In this work, we propose a graph-based approach for detecting tables in document images. Instead of using the raw content (recognized text), we make use of the location, context and content type, thus it is purely a structure perception approach, not dependent on the language and the quality of the text reading. Our framework makes use of Graph Neural Networks (GNNs) in order to describe the local repetitive structural information of tables in invoice documents. Our proposed model has been experimentally validated in two invoice datasets and achieved encouraging results. Additionally, due to the scarcity of benchmark datasets for this task, we have contributed to the community a novel dataset derived from the RVL-CDIP invoice data. It will be publicly released to facilitate future research.European Unio

The endogenous hallucinogen and trace amine N,N-dimethyltryptamine (DMT) displays potent protective effects against hypoxia via sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells

N,N-dimethyltryptamine (DMT) is a potent endogenous hallucinogen present in the brain of humans and other mammals. Despite extensive research, its physiological role remains largely unknown. Recently, DMT has been found to activate the sigma-1 receptor (Sig-1R), an intracellular chaperone fulfilling an interface role between the endoplasmic reticulum (ER) and mitochondria. It ensures the correct transmission of ER stress into the nucleus resulting in the enhanced production of antistress and antioxidant proteins. Due to this function, the activation of Sig-1R can mitigate the outcome of hypoxia or oxidative stress. In this paper, we aimed to test the hypothesis that DMT plays a neuroprotective role in the brain by activating the Sig-1R. We tested whether DMT can mitigate hypoxic stress in in vitro cultured human cortical neurons (derived from induced pluripotent stem cells, iPSCs), monocyte-derived macrophages (moMACs), and dendritic cells (moDCs). Results showed that DMT robustly increases the survival of these cell types in severe hypoxia (0.5% O2) through the Sig-1R. Furthermore, this phenomenon is associated with the decreased expression and function of the alpha subunit of the hypoxia-inducible factor 1 (HIF-1) suggesting that DMT-mediated Sig-1R activation may alleviate hypoxia-induced cellular stress and increase survival in a HIF-1-independent manner. Our results reveal a novel and important role of DMT in human cellular physiology. We postulate that this compound may be endogenously generated in situations of stress, ameliorating the adverse effects of hypoxic/ischemic insult to the brain.publishedVersio

depressive spectrum disorders in cancer prevalence risk factors and screening for depression a critical review

AbstractBackground: Although depression and mood-related disorders are common in persons with cancer, these conditions remain frequently overlooked in clinical practice. Negative consequences of depressive disorder spectrum have been reported (e.g. suicidal ideation, increase physical complications and somatic symptoms, negative influence on prognosis), indicating the need for routine screening, assessment and management.Methods: A search of the major databases (Medline, Embase, PsycLIT, PsycINFO, and the Cochrane Library) was conducted on the reviews and meta-analyses available in order to summarize relevant data concerning depressive disorders spectrum in terms of prevalence, risk factors, and screening and assessment among patients with cancer across the trajectory of the disease.Results: The data show a prevalence of depression and depressive disorders between 5% and 60% according to the different diagnostic criteria, the tools used in the studies (e.g. semi-structured psychiatric interview and psycho..

Carbamazepine-Associated Hyponatremia

Four cases of CBZ-induced or exacerbated hyponatremia are described in middle-aged to elderly females. Two cases are remarkable in that the pretreatment sodium levels demonstrate hyponatremia. A return to prior sodium levels was observed upon the discontinuation of carbamazepine therapy. No definitive conclusions can be drawn from these case reports; however, similarities in the cases can be examined as follows: (1) all four women have medical problems, in particular two patients had pre-existing hyponatremia; (2) all four patients were using concurrent medications; (3) all four women presented psychotic. A literature review examines risk factors, pharmacological mechanism, and the time course for CBZ-induced hyponatremia

Size and shape evolution of embedded single-crystal αα-Fe nanowires

The size and shape evolution of embedded ferromagnetic αα-Fe nanowires is discussed. The αα-Fe nanowires are formed by pulsed-laser deposition of La0.5Sr0.5FeO3−xLa0.5Sr0.5FeO3−x on single-crystal SrTiO3SrTiO3 (001) substrate in reducing atmosphere. The average diameter of the nanowires increases from d ≈ 4d≈4 to 50 nm as the growth temperature increases from T = 560T=560 to 840 °C. Their in-plane shape evolves from circular to octahedral and square shape with [110] facets dominating as the growth temperature increases. A fitting to a theoretical calculation shows that the circular shape is stable when the diameter of the nanowires is smaller than 8 nm.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87835/2/203110_1.pd

Raman microprobe observation of intercalate contraction in graphite intercalation compounds

Raman microprobe spectra of SbCl5, Br2, and FeCl3 graphite intercalation compounds have been obtained with a spatial resolution of 2 m. Depletion of the intercalate was observed within 10 m of the sample edge in the SbCl5-graphite samples, and this observation is found to be consistent with a model in which the intercalate contracts thermally as the sample is cooled after the intercalation reaction is completed. No depletion was observed in the Br2 and FeCl3 graphite intercalation compounds, consistent with the low intercalation temperature of the former and the small thermal expansion coefficient of the latter