Pancreatitis following Olanzapine Therapy: A Report of Three Cases

CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being treated with olanzapine. The mean age of the patients was 37.7 years (range 18–54 years, 2 female, 1 male). No alternative cause of acute pancreatitis was found in two of the three patients. In the remaining patient, olanzapine may have contributed to acute pancreatitis in the setting of hypertriglyceridemia. Olanzapine was discontinued in all instances. Over a mean follow-up of 14 months, one patient has had a relapsing course, but the remaining two patients have been symptom free without recurrence of acute pancreatitis. CONCLUSIONS: Our case series adds further support to the potential link between olanzapine use and acute pancreatitis. Close monitoring of metabolic parameters is suggested in patients treated with olanzapine. Alternative antipsychotic agents should be considered in patients at high risk for pancreatitis

Projective and non-projective systems of first order nonlinear differential equations

It is well established that many physical and chemical phenomena such as those in chemical reaction kinetics, laser cavities, rotating fluids, and in plasmas and in solid state physics are governed by nonlinear differential equations whose solutions are of variable character and even may lack regularities. Such systems are usually first studied qualitatively by examining their temporal behavior near singular points of their phase portrait. In this work we will be concerned with systems governed by the time evolution equations [see PDF for mathematical formulas] The xi may generally be considered to be concentrations of species in a chemical reaction, in which case the k\u27s are rate constants. In some cases the xi may be considered to be position and momentum variables in a mechanical system. We will divide the equations into two classes: those in which the evolution can be carried out by the action of one of Lie\u27s transformation groups of the plane, and those for which this is not possible. Members of the first class can be integrated by quadrature either directly or by use of an integrating factor; those in the second class cannot. Of those in the first class the most interesting evolve by transformations of the projective group, and these, as well as the equations that cannot be integrated by quadrature, we study in some detail. We seek a qualitative analysis of systems which have no linear terms in their evolution equations when the origin from which the xi are measured is a critical point. The standard, linear, phase plane analysis is of course not adequate for our purposes

Évolution de la température de l’air et des précipitations dans la région côtière syrienne (gouvernorat de Lattaquié) de 1970 à 2016

This study aims to analyze the changes in the annual and seasonal averages of air temperature and precipitation over Lattakia Governorate during the period 1970-2016. Annual and seasonal trends for temperature and precipitation were calculated by using the non-parametric Mann-Kendall test. The mean differences between the two periods 1970-2000 and 2001-2016, were assessed at the annual and seasonal scales by using the non-parametric Mann-Whitney U test. Furthermore, the occurrence of extreme high/low values were analyzed at the annual scale by using the normal distribution curve. The study found that the annual temperature averages significantly (p<0.05) increased by 0.22 ˚C/decade and 0.17 ˚C/decade, respectively at Lattakia and Hiffeh stations during the period 1970-2016. Summer exhibited strong and significant (at level 0.01) increasing trends by 0.39 ˚C/decade at Lattakia, and by 0.34 ˚C/decade at Hiffeh. Total spring precipitation significantly decreased by -6.5 mm/decade at Lattakia and by -12.1 mm/decade at Hiffeh. Probability of the occurrence of the value 20.2 ˚C or more as an extreme value increased by 40.8% at Lattakia station during the period 2001-2016. Este estudio tiene como objetivo analizar los cambios en los promedios anuales y estacionales de la temperatura del aire y las precipitaciones en la gobernación de Lattakia durante 1970-2016. Las tendencias anuales y estacionales para la temperatura y la precipitación se calcularon utilizando la prueba no paramétrica de Mann-Kendall. Las diferencias de medias entre los dos períodos (1970-2000) / (2001-2016) se evaluaron en los niveles anuales y estacionales mediante el uso de la prueba no paramétrica de Mann-Whitney U. Además, la aparición de valores extremadamente altos / bajos se analizó a nivel anual mediante el uso de la curva de distribución normal. El estudio encontró que los promedios anuales de temperatura aumentaron significativamente (p <0.05) en 0.22 ˚C / década y 0.17 ˚C \ década, en las estaciones de Lattakia y Hiffeh, respectivamente, durante 1970-2016. El verano reveló tendencias fuertes y significativas al alza (a nivel 0.01) en sus promedios de temperatura en 0.39 ˚C / década en Lattakia, y en 0.34 ˚C / década en Hiffeh. El promedio de precipitaciones de primavera disminuyó significativamente en -6.5 mm / década en Lattakia y en -12.1 mm / década en Hiffeh. La probabilidad de la aparición del valor de 20.2 ˚C o más como valor extremo aumentó en la estación de Lattakia durante 2001-2016 en un 40.8%.L’objectif de cette étude est d’analyser les changements dans les moyennes annuelles et saisonnières de la température de l’air et des précipitations sur la région du gouvernorat de Lattaquié entre 1970 et 2016. Les tendances annuelles et saisonnières de la température ont été calculées à l’aide du test non-paramétrique de Mann-Kendall. Les différences moyennes entre les périodes 1970-2000 et 2001-2016 ont été évaluées par année et saison en utilisant le test non-paramétrique de Mann-Whitney U. En ce qui concerne l’occurence de valeurs extrêmement élevées/ basses, celle-ci a été analysée sur une base annuelle en utilisant la courbe de distribution normale. L’étude a révélé que les températures moyennes annuelles (p<0,05) ont augmenté significativement de 0,22 ˚C / décennie et de 0,17 ˚C / décennie, dans les cas respectifs des stations de Lattakia et de Haffah durant la période 1970-2016. L’été a laissé voir une tendance marquée à la hausse (au niveau de 0,01) de ses moyennes de température : 0,39 ˚C / décennie à Lattaquié et 0,34 ˚C / décennie à Hiffeh. La moyenne des précipitations printanières a diminué de manière significative, soit de -6,5 mm / décennie à Lattakia et de -12,1 mm / décennie à Hiffeh. La probabilité d’apparition de la valeur de 20,2 ˚C ou plus comme valeur extrême a augmenté de 40,8% pour la station de Lattaquié pendant la période 2001-2016

Epitaxial thin films of multiferroic Bi2FeCrO6 with B-site cationic order

Epitaxial thin films of Bi2FeCrO6 have been synthesized by pulsed laser deposition on SrRuO3 on (100)- and (111)-oriented SrTiO3 substrates. Detailed X-ray diffraction and cross-section transmission electron microscopy analysis revealed a double perovskite crystal structure of the Bi2FeCrO6 epitaxial films very similar to that of BiFeO3 along with a particularly noteworthy Fe3+/Cr3+ cation ordering along the [111] direction. The films contain no detectable magnetic iron oxide impurities and have the correct cationic average stoichiometry throughout their thickness. They however exhibit a slight modulation in the Fe and Cr compositions forming complementary stripe patterns, suggesting minor local excess or depletion of Fe and Cr. The epitaxial BFCO films exhibit good ferroelectric and piezoelectric properties, in addition to magnetic properties at room temperature, as well as an unexpected crystallographic orientation dependence of their room temperature magnetic properties. Our results qualitatively confirm the predictions made using the ab-initio calculations: the double-perovskite structure of Bi2FeCrO6 films exhibit a Fe3+/Cr3+ cation ordering and good multiferroic properties, along with the unpredicted existence of magnetic ordering at room temperature.Comment: Accepted for publication in Journal of Materials Researc

Food composition and feeding ecology of the Red Fox Vulpes vulpes (Linnaeus, 1758) in Egypt

Food composition of the Red Fox Vulpes vulpes populations in different habitats in Egypt is investigated based on the analysis of stomach contents. The analysis of 70 stomach contents demonstrates that the food of Red Fox is highly diverse and includes rodents, birds, reptiles,fishes, insects and other arthropods, fruits and other vegetable material. Certain individuals seem to also feed on carrion. Diet composition shows seasonal and geographical variations that are apparently associated with changes in the availability of different food items. The results clearlyshow that the Red Fox is an opportunistic omnivore, capable of adapting to a great variety of dietary compositions