O ASSÉDIO PROCESSUAL: UMA ANÁLISE A PARTIR DO IMPERATIVO CATEGÓRICO KANTIANO

O Código de Processo Civil estabeleceu já em seu dispositivo inaugural uma interlocução do processo com a Constituição Federal. Reafirmou este como instrumento de cidadania e democracia participativa e, justamente por isso, revelou o seu compromisso com a ética. Uma ética que não independe de agências externas para se consolidar, senão do próprio indivíduo, baseado na máxima Kantiana. O Digesto enumerou pontualmente algumas situações violadoras dessa ética, trazendo, entretanto, a cláusula geral da boa-fé objetiva, capaz de tutelar um número indefinido de situações, inclusive o abuso processual, que se pretende conceituar, mediante revisão bibliográfica e situar na práxis forense

INBREEDING DEPRESSION AND GENETIC VARIABILITY IN NELLORE BREED

Inbreeding depression is caused by breeding between closely relatedindividuals and can have a significant negative impact on cattle production. It can be estimated at the population level using pedigree analysis or molecular markers. Such estimations can then be used to better manage the genetic resources of herds. The objective of this study was to evaluate genetic variability and the influence of inbreeding depression on productive traits in 45 785 animals Nellore cattle (polled variety) from Brazil. Inbreeding depression was determined by fitting four regression models (linear, quadratic, exponential and Michaelis-Menten) to the errors generated by the animal model. The traits studied were weight at 205 (W205), 365 (W365) and 550 (W550) days of age. The effective number of founders (fe) and ancestors (fa) was 288 and 283, respectively, with 173 ancestors explaining 50% of the genetic variability in the population. Inbreeding depression effects were identified on all growth traits (W205, W365, and W550), demonstrating significant losses in evaluated weight means. For each 1% increase in inbreeding there was a depression of about 0.14% or 0.24 kg (W205), 0.12% or 0.29 kg (W365) and 0.09%or 0.29 kg (W550). Exponential and Michaelis-Menten models were similarly efficient predictors for all the traits (P<0.01). We conclude that Nellore cattle in Northeastern Brazil presents low genetic variation and the relationship between inbreeding and depressed productivity in this breed is not linear, with the greatest effects occurring when endogamy is above 20%. To change this scenario, it is important to use a high number of male breeders, mainly young individuals of high breeding value, and improvement of reproductive indexes of females. To achieve this goal, a traditional mating system focused on the utilization of a few (and famous) male breeders should be avoided by both farmers and technicians

Parâmetros populacionais da raça ovina Santa Inês no Brasil

The objective of this work was to evaluate the population structure of the sheep breed Santa Inês raised in Brazil. Pedigree data from 13,216 animals, belonging to 53 herds from eight Brazilian states, born between 1976 and 2010, were used. The program Endog was used for pedigree analysis and estimation of population parameters. From the total number of animals studied, 80.86% had a pedigree in the first ascendancy, 73.78% in the second, and 67.75% in the third. The maximum number of known generations was 19, and the average of equivalent generations was 4.67. The average generation interval was 3.22±1.77 years. The mean effective population size was of 172.5 animals. The number of founder animals was 829, but the effective number of founders was only 50. The 17 main ancestors accounted for 50% of the total genetic variability. The average relatedness coefficient was of 3.87% and the average inbreeding coefficient, of 6.92%. Despite the satisfactory average inbreeding coefficient in recent generations, this coefficient requires monitoring because of its proximity to the recommended limit. Gene flow among herds is the main factor for the increase of effective size and the maintenance of genetic variability in the breed Santa Inês.O objetivo deste trabalho foi avaliar a estrutura populacional de ovinos da raça Santa Inês criados no Brasil. Foram utilizados dados de pedigree de 13.216 animais, pertencentes a 53 rebanhos de oito estados brasileiros, nascidos no período de 1976 a 2010. O programa Endog foi utilizado para análise do pedigree e estimação dos parâmetros populacionais. Do total de animais estudados, 80,86% apresentaram pedigree na primeira ascendência, 73,78% na segunda e 67,75% na terceira. O número máximo de gerações conhecidas foi de 19, e a média de gerações equivalentes foi de 4,67. A média do intervalo de gerações foi de 3,22±1,77 anos. O tamanho efetivo da população apresentou média de 172,5 animais. O número de animais fundadores foi 829, mas o número efetivo de fundadores foi apenas 50. Os 17 principais ancestrais explicaram 50% da variabilidade genética total. O coeficiente médio de relação foi de 3,87% e o de endogamia, de 6,92%. Apesar do satisfatório coeficiente médio de endogamia nas últimas gerações, este coeficiente requer monitoramento por sua proximidade do limite recomendável. O fluxo de genes entre os rebanhos é o principal fator para o aumento do tamanho efetivo e a manutenção da variabilidade genética da raça Santa Inês

Morphofunctional characteristics of Dorper sheep crossed with Brazilian native breeds

Abstract The relationship between body development and external measures in sheep could provide useful information to define the optimal slaughter time as well as the adequate nutritional management. Thus, the objective of this study was to evaluate the morpho-functional diversity of Dorper sheep crossed with Brazilian native breeds using in vivo morphometric analysis. The animals evaluated were from crosses of Dorper with Morada Nova, Rabo Largo and Santa Ines sheeps. The animals were slaughtered at 120 and 240 days of age. Body and carcass measures, weight of meat cuts and growth were evaluated. The crossbred animals were analyzed by sex, totaling six treatments. A factorial analysis was performed using two sets of data: the in vivo morphometric measures, and all the other characteristics and these factors were used as new variables. The differences among treatments were analyzed using MANOVA and canonical analysis. The meat cuts, conformation, marketability adaptation, and early maturity of the animals slaughtered at 120 days, as well as the meat cuts, conformation, adaptation, early maturity, and hindquarter of the animals slaughtered at 240 days were evaluated. As regards body measurements, at both slaughter ages, the following factors were discriminated: height, robustness, length, and thoracic circumference. Animal slaughtered at 120 days of age showed greater differences whereas at 240 days the differences diminished allowing to individuate which treatments were more adaptive or productive. Crosses ½ Dorper × ½ Santa Ines (male and female), and ½ Dorper × ½ Rabo Largo male slaughtered at 240 days seem to show higher productivity and better marketability abilities. The other crosses tend to have a more rustic profile (less productive) and smaller size, reaching however adult size earlier and showing better adaptive characteristics, which allows to decide for slaughtering at younger ages

Editing and modeling of milk production data for genetic evaluation of Murrah buffaloes

O objetivo deste trabalho foi verificar as consequências da edição e modelagem da produção de leite para avaliação genética de bubalinos da raça Murrah. Foram analisadas seis estratégias para avaliação da produção de leite: produção de leite observada (PL_OBS); ajuste para a produção de leite aos 305 dias (PL_305) e aos 270 dias (PL_270); exclusões dos 5 e 10% menores períodos de lactação (PL_5% e PL_10%) e duração da lactação como covariável linear (PL_CO). Os parâmetros genéticos foram estimados por meio de inferência Bayesiana, com estimativas de herdabilidades e repetibilidades de 0,19 a 0,23 e 0,35 a 0,36, respectivamente. Touros classificados pelo PL_OBS apresentaram altas correlações com os que foram classificados pelos outros modelos. Contudo, ao considerar apenas os 20% melhores touros, verificou-se diminuição das correlações de PL_270, PL_305 e PL_CO com PL_OBS. Maiores diferenças dos desvios médios absolutos do PL_OBS foram com PL_CO, PL_270 e PL_305. As estratégias de análise apresentaram herdabilidades  e estabilidade semelhantes. Contudo, as inversões de posições dos touros com melhores classificações, como consequencia das superestimativas dos valores genéticos nos modelos PL305, PL270 e PL_CO podem acarretar em diminuição do progresso genético nos rebanhos.The objective of this work was to assess the effect of editing and modeling of milk production data for genetic evaluation of Murrah buffaloes. Six strategies for evaluating milk production were analyzed: observed milk production (OMP); adjustment of milk production data to 305 (MP305) and 270 (MP270) days of lactation; removal of the 5 (MP5%) and 10% (MP10%) shortest lactation periods; and milk production along the lactation period as linear covariate (MPCO). Genetic parameters were estimated using the Bayesian inference, with heritability estimates of 0.19 to 0.23 and repeatability estimates of 0.35 to 0.36. Sires classified by OMP were high correlated to those classified by the other models, however, correlations to MP270, MP305 and MPCO decreased when considering only the best 20% sires. OMP showed greater differences in absolute mean deviations when compared with MPCO, MP270 and MP305. The strategies of analysis had similar heritabilities and stabilities. However, changes in the ranking of sires with better classifications, due to overestimation of genetic values, as occurred in the models MP305, MP270 and MPCO, may lead to a decrease in the genetic progress of the herd

ESTRUTURA POPULACIONAL DO REBANHO NELORE CRIADO NO SEMIÁRIDO DO NORDESTE BRASILEIRO

Objetivou-se avaliar a estrutura populacional de 91.579 animais da raça Nelore criados no Semiárido Nordestino, nascidos entre 1965 e 2011. Analisaram-se o pedigree e a estimação dos parâmetros populacionais baseados na probabilidade de origem do gene. Nos primeiros anos, registraram-se nascimentos superiores de fêmeas, tendendo ao equilíbrio entre os sexos com o passar dos anos. Os números de efetivo de animais fundadores (fe) e ancestrais (fa) indicaram a utilização reduzida de animais na formação genética do rebanho. Dentre 24.676 ancestrais, 450 foram responsáveis por 50% da variabilidade genética da população. Dos 10 fundadores de maior importância, 8 se apresentam dentre os 10 ancestrais; o indivíduo com maior expressão apresentou coeficiente de relação médio (CR) de 1,31%, explicando 1,81% da variabilidade. 72% dos animais têm pais e mães identificados, observando-se perda de informação entre as gerações. 100% dos rebanhos utilizam touros externos e 61% deles vendem touros, não havendo classificação núcleo ou isolado. Endogamia variou de 0,14% na segunda geração a 0,73% na oitava, enquanto que o CR oscilou de 0,8% a 0,35% entre a primeira e a quarta geração, decrescendo a partir da quinta. Observou-se um intervalo médio de gerações de 8,3 anos. O rebanho possui número reduzido de animais na formação genética e pequena integralidade do pedigree, dificultando a estimativa de alguns parâmetros populacionais. Palavras-chave: endogamia; intervalo de gerações; variabilidade genética; zebuínos

POPULATION STRUCTURE OF THE NELLORE HERD REARED IN THE BRAZILIAN NORTHEAST SEMI-ARID

The objective of this study was to evaluate the population structure of 91,579 Nellore cattle reared in the Northeast semi-arid, born between 1965 and 2011. We analyzed the pedigree and the estimation of population parameters based on the probability of gene origin. In the early years, a higher number of female births occured, tending to gender balance over the years. The number of founder animals (fe) and ancestors (fa) indicated the reduced use of animals in the genetic formation of the herd. Among 2,4676 ancestors, 450 were responsible for 50% of the genetic variability of the population. Of the 10 most important founders, 8 were among the 10 ancestors. The individual with the highest expression presented a mean coefficient of relationship (CR) of 1.31%, explaining 1.81% of the variability.72% of animals have identified fathers and mothers, revealing loss of information between generations. 100% of the herds use external bulls and 61% of them sell bulls, with no core classification or isolate. Inbreeding ranged from 0.14% in the second generation to 0.73% in the eighth, while the CR ranged from 0.8% to 0.35% between the first and fourth generations, decreasing from the fifth on. The average generation interval observed was of 8.3 years. The herd has a small number of animals in the genetic make-up, and small completeness of pedigree, making it difficult to estimate some population parameters. Keywords: generation interval; genetic variability; inbreeding; Zebu

Marine biotechnology in Brazil : recent developments and its potential for innovation

Marine biotechnology is an emerging field in Brazil and includes the exploration of marine microbial products, aquaculture, omics, isolation of biologically active compounds, identification of biosynthetic gene clusters from symbiotic microorganisms, investigation of invertebrate diseases caused by potentially pathogenic marine microbes, and development of antifouling compounds. Furthermore, the field also encompasses description of new biological niches, current threats, preservation strategies as well as its biotechnological potential. Finally, it is important to depict some of the major approaches and tools being employed to such end. To address the challenges of marine biotechnology, the Brazilian government, through the Ministry of Science, Technology, Innovation, and Communication, has established the National Research Network in Marine Biotechnology (BiotecMar) (www.biotecmar.sage.coppe.ufrj.br). Its main objective is to harness marine biodiversity and develop the marine bioeconomy through innovative research