Advection-Dominated Accretion with Infall and Outflows

We present self-similar solutions for advection-dominated accretion flows with radial viscous force in the presence of outflows from the accretion flow or infall. The axisymmetric flow is treated in variables integrated over polar sections and the effects of infall and outflows on the accretion flow are parametrised for possible configurations compatible with the self-similar solution. We investigate the resulting accretion flows for three different viscosity laws and derive upper limits on the viscosity parameter alpha. In addition, we find a natural connection to non-rotating and spherical accretion with turbulent viscosity, which is assumed to persist even without differential rotation. Positive Bernoulli numbers for advection-dominated accretion allow a fraction of the gas to be expelled in an outflow and the upper limit on the viscosity predicts that outflows are inevitable for equations of state close to an ideal gas.Comment: 17 pages, 9 figures, accepted for publication in the Astrophysical Journa

'HeART of Stroke (HoS)', a community-based Arts for Health group intervention to support self-confidence and psychological well-being following a stroke: protocol for a randomised controlled feasibility study

Introduction Over 152 000 people in the UK have strokes annually and a third experience residual disability. Low mood also affects a third of stroke survivors; yet psychological support is poor. While Arts for Health interventions have been shown to improve well-being in people with mild-to-moderate depression post-stroke, their role in helping people regain sense of self, well-being and confidence has yet to be evaluated. The main aim of this study is to explore the feasibility of conducting a pragmatic multicentre randomised controlled trial to assess the effectiveness and cost-effectiveness of an Arts for Health group intervention (‘HeART of Stroke’ (HoS)) for stroke survivors. HoS is a 10-session artist-facilitated group intervention held in the community over 14 weeks. It offers a non-judgemental, supportive environment for people to explore sense of self, potentially enhancing well-being and confidence. Methods and analysis Sixty-four people, up to 2 years post-stroke, recruited via secondary care research staff or community stroke/rehabilitation teams in two UK centres will be randomised to either HoS plus usual care or usual care only. Self-reported outcomes, measured at baseline and approximately 5 months postrandomisation, will include stroke-related, well-being, mood, self-esteem, quality of life and process measures. Analyses will focus on estimating key feasibility parameters (eg, rates of recruitment, retention, intervention attendance). We will develop outcome and resource use data collection methods to inform an effectiveness and cost-effectiveness analysis in the future trial. Interviews, with a sample of participants, will explore the acceptability of the intervention and study processes, as well as experiences of the HoS group. Ethics and dissemination National Health Service (NHS), Research and Development and University ethical approvals have been obtained. Two peer-reviewed journal publications are planned plus one service user led publication. Findings will be disseminated at key national conferences, local stakeholder events and via institutional websites.This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit (RfPB) Programme (Grant Reference Number PB-PG-0212-27054)

What systems are essential to achieving the sustainable development goals and what will it take to marshal them?

The sustainable development goal (SDG) for health is linked to 67 indicators, eight times more than their predecessor, the Millenium Development Goals. In many low- and middle-income countries (LMICs), the information infrastructure is not yet able to collect and use the data needed for the indicators. As they seek to be responsive to the SDG agenda, LMICs must not lose sight of their local data needs; they should be cautious about embracing untested electronic technologies for data collection, analysis, and use; carefully balance the care provision and data collection responsibilities of care providers; and use evidence of what works in strengthening their health information systems (HIS). While attending to these concerns, countries can look for instances in which SDG indicators are in sync with their own HIS goals

The Beagle 2 optical microscope

Introduction to the Beagle2 optical microscope

Improving referrals and integrating family planning and HIV services through organizational network strengthening

BACKGROUND: The service needs of people with human immunodeficiency virus (HIV) in low-income settings are wide-ranging. Service provision in a community is often disjointed among a variety of providers. We sought to reduce unmet patient needs by increasing referral coordination for HIV and family planning, measured as network density, with an organizational network approach. METHODS: We conducted organizational network analysis on two networks in sub-cities of Addis Ababa, Ethiopia. There were 25 organizations in one sub-city network and 26 in the other. In one of them we sought to increase referrals through three network strengthening meetings. We then conducted the network analysis again in both sub-cities to measure any changes since baseline. We also quantitatively measured reported client service needs in both sub-cities before and after the intervention with two cross-sectional samples of face-to-face interviews with clients (459 at baseline and 587 at follow-up). RESULTS: In the sub-city with the intervention, the number of referral connections between organizations, measured as network density, increased 55%. In the control community, the density decreased over the same period. Reported unmet client service needs declined more consistently across services in the intervention community. DISCUSSION: This quasi experiment demonstrated that (1) an organizational network analysis can inform an intervention, (2) a modest network strengthening intervention can enhance client referrals in the network, (3) improvement in client referrals was accompanied by a decrease in atient-reported unmet needs and (4) a series of network analyses can be a useful evaluation tool

A Systematic Review of the Core Components of Language Learning Strategy Research in Taiwan

As the broader field of individual differences in second/foreign language learning has grown tremendously over the past few decades, its subfields have expanded with a similar intensity. Language learning strategies (LLS) is one such area. Developments have been made regarding the scope and methodology of LLS research, especially. While there have been a number of reviews of the field’s output, few have targeted research in a specific context. With this in mind, the current study offers a situated view of LLS research in Taiwan. It focuses on three core components that are essential to empirical research: (a) contexts and participant characteristics; (b) theoretical-conceptual aspects; and (c) methodological characteristics. Drawing on journal articles systematically collected from major databases and reviews conducted by multiple researchers to ensure reliability and to minimize bias, we provide an overview of the field as it has manifested in Taiwan. Findings from select studies are also discussed. In doing so, this article makes connections between LLS research in Taiwan and the larger, global context, with implications for "the road ahead." We hope it will be a valuable resource for anyone interested in reading about and/or conducting LLS research in this setting and others

Solvent extraction of PDMS tubing as a new method for the capture of volatile organic compounds from headspace

Polydimethylsiloxane (PDMS) tubing is increasingly being used to collect volatile organic compounds (VOCs) from static biological headspace. However, analysis of VOCs collected using PDMS tubing often deploys thermal desorption, where samples are considered as ‘one-offs’ and cannot be used in multiple experiments. In this study, we developed a static headspace VOC collection method using PDMS tubing which is solvent-based, meaning that VOC extracts can be used multiple times and can be linked to biological activity. Using a synthetic blend containing a range of known semiochemicals (allyl isothiocyanate, (Z)-3-hexen-1-ol, 1-octen-3-one, nonanal, (E)-anethol, (S)-bornyl acetate, (E)-caryophyllene and pentadecane) with differing chemical and physicochemical properties, VOCs were collected in static headspace by exposure to PDMS tubing with differing doses, sampling times and lengths. In a second experiment, VOCs from oranges were collected using PDMS sampling of static headspace versus dynamic headspace collection. VOCs were eluted with diethyl ether and analysed using gas chromatography – flame ionization detector analysis and coupled GC – mass spectrometry analysis. GC-FID analysis of collected samples showed that longer PDMS tubes captured significantly greater quantities of compounds than shorter tubes, and that sampling duration significantly altered the recovery of all tested compounds. Moreover, greater quantities of compounds were recovered from closed compared to open systems. Finally, analysis of orange headspace VOCs showed only a few qualitative differences in VOCs recovered compared to dynamic headspace collections, although quantities sampled using PDMS tubing were lower. In summary, extraction of PDMS tubing with diethyl ether solvent captures VOCs from the headspace of synthetic blends and biological samples, and the resulting extracts can be used for multiple experiments linking VOC content to biological activity

Confluence via strong normalisation in an algebraic \lambda-calculus with rewriting

The linear-algebraic lambda-calculus and the algebraic lambda-calculus are untyped lambda-calculi extended with arbitrary linear combinations of terms. The former presents the axioms of linear algebra in the form of a rewrite system, while the latter uses equalities. When given by rewrites, algebraic lambda-calculi are not confluent unless further restrictions are added. We provide a type system for the linear-algebraic lambda-calculus enforcing strong normalisation, which gives back confluence. The type system allows an abstract interpretation in System F.Comment: In Proceedings LSFA 2011, arXiv:1203.542

The X-ray Warm Absorber in NGC3516

The Seyfert 1 galaxy, NGC3516 has been the subject of many absorption line studies at both ultraviolet and X-ray wavelengths. In the UV, strong, broad, variable associated metal line absorption with velocity width $\sim 2000$ \kms\ is thought to originate in gas with nh larger than about $10^{19}$ cm$^{-2}$ lying between 0.01 and 9 pc from the central active nucleus. The Ginga X-ray data are consistent with several possibilities: a warm absorber and a cold absorber combined either with partial covering or an unusually strong reflection spectrum. We present ROSAT observations of NGC3516 which show a strong detection of a warm absorber dominated by a blend of OVII/OVIII edges at $\sim$ 0.8 keV with nh $\sim 7\times 10^{21}$ cm$^{-2}$ and U: 8--12. We argue that NGC3516 contains an outflowing `XUV' absorber showing the presence of X-ray absorption edges, that are consistent with the presence of broad absorption lines in the old IUE spectra and their disappearance in the new UV observations. Our dynamical model suggests that the OVII absorption edge will continue to weaken compared to the OVIII edge, an easily testable prediction with future missions like AXAF. Eventually the source would be transparent to the X-rays unless a new absorption system is produced.Comment: 24 pages with 5 figures. To appear in the Ap.J. Requires AAS macro