Design of an electrostatic balance mechanism to measure optical power of 100 kW

A new instrument is required to accommodate the need for increased portability and accuracy in laser power measurement above 100 W. Reflection and absorption of laser light provide a measurable force from photon momentum exchange that is directly proportional to laser power, which can be measured with an electrostatic balance traceable to the SI. We aim for a relative uncertainty of $10^{-3}$ with coverage factor $k=2$. For this purpose, we have designed a monolithic parallelogram 4-bar linkage incorporating elastic circular notch flexure hinges. The design is optimized to address the main factors driving force measurement uncertainty from the balance mechanism: corner loading errors, balance stiffness, stress in the flexure hinges, sensitivity to vibration, and sensitivity to thermal gradients. Parasitic rotations in the free end of the 4-bar linkage during arcuate motion are constrained by machining tolerances. An analytical model shows this affects the force measurement less than 0.01 percent. Incorporating an inverted pendulum reduces the stiffness of the system without unduly increasing tilt sensitivity. Finite element modeling of the flexures is used to determine the hinge orientation that minimizes stress which is therefore expected to minimize hysteresis. Thermal effects are mitigated using an external enclosure to minimize temperature gradients, although a quantitative analysis of this effect is not carried out. These analyses show the optimized mechanism is expected to contribute less than $10^{-3}$ relative uncertainty in the final laser power measurement.Comment: 11 pages, 9 figures, accepted for publication in IEEE Transactions on Instrumentation and Measuremen

Preliminary characterization of anelastic effects in the flexure mechanism for a new Kibble balance at NIST

A new Kibble balance is being built at the National Institute of Standards and Technology (NIST). For the first time in one of the highly accurate versions of this type of balance, a single flexure mechanism is used for both modes of operation: the weighing mode and the velocity mode. The mechanism is at the core of the new balance design as it represents a paradigm shift for NIST away from using knife edge-based balance mechanisms, which exhibit hysteresis in the measurement procedure of the weighing mode. Mechanical hysteresis may be a limiting factor in the performance of highly accurate Kibble balances approaching single digit nanonewton repeatability on a nominal 100 g mass, as targeted in this work. Flexure-based mechanisms are known to have very good static hysteresis when used as a null detector. However, for larger and especially longer lasting deformations, flexures are known to exhibit anelastic drift. We seek to characterize, and ideally compensate for, this anelastic behavior after deflections during the velocity mode to enable a 10 accurate Kibble balancemeasurement on a nominal 100 g mass artifact with a single flexure-based balance mechanism

Free-range grazing by large herbivores in degraded large-scale dry sandy grassland-heathland ecosystems

Free-range grazing by large herbivores combined with one-time mowing of over-aged heathlands offers an excellent management tool to maintain and enhance biodiversity in degraded large scale, low productive, semi-open dry sandy grassland-heathland ecosystems. Grazing improves habitat quality, supports typical species communities and represses invasive species

Inferring Implicit 3D Representations from Human Figures on Pictorial Maps

In this work, we present an automated workflow to bring human figures, one of the most frequently appearing entities on pictorial maps, to the third dimension. Our workflow is based on training data and neural networks for single-view 3D reconstruction of real humans from photos. We first let a network consisting of fully connected layers estimate the depth coordinate of 2D pose points. The gained 3D pose points are inputted together with 2D masks of body parts into a deep implicit surface network to infer 3D signed distance fields (SDFs). By assembling all body parts, we derive 2D depth images and body part masks of the whole figure for different views, which are fed into a fully convolutional network to predict UV images. These UV images and the texture for the given perspective are inserted into a generative network to inpaint the textures for the other views. The textures are enhanced by a cartoonization network and facial details are resynthesized by an autoencoder. Finally, the generated textures are assigned to the inferred body parts in a ray marcher. We test our workflow with 12 pictorial human figures after having validated several network configurations. The created 3D models look generally promising, especially when considering the challenges of silhouette-based 3D recovery and real-time rendering of the implicit SDFs. Further improvement is needed to reduce gaps between the body parts and to add pictorial details to the textures. Overall, the constructed figures may be used for animation and storytelling in digital 3D maps.Comment: to be published in 'Cartography and Geographic Information Science

LINC01133 inhibits invasion and promotes proliferation in an endometriosis epithelial cell line

Endometriosis is a common gynecological disorder characterized by ectopic growth of endometrium outside the uterus and is associated with chronic pain and infertility. We investigated the role of the long intergenic noncoding RNA 01133 (LINC01133) in endometriosis, an lncRNA that has been implicated in several types of cancer. We found that LINC01133 is upregulated in ectopic endometriotic lesions. As expression appeared higher in the epithelial endometrial layer, we performed a siRNA knockdown of LINC01133 in an endometriosis epithelial cell line. Phenotypic assays indicated that LINC01133 may promote proliferation and suppress cellular migration, and affect the cytoskeleton and morphology of the cells. Gene ontology analysis of differentially expressed genes indicated that cell proliferation and migration pathways were affected in line with the observed phenotype. We validated upregulation of p21 and downregulation of Cyclin A at the protein level, which together with the quantification of the DNA content using fluorescence-activated cell sorting (FACS) analysis indicated that the observed effects on cellular proliferation may be due to changes in cell cycle. Further, we found testis-specific protein kinase 1 (TESK1) kinase upregulation corresponding with phosphorylation and inactivation of actin severing protein Cofilin, which could explain changes in the cytoskeleton and cellular migration. These results indicate that endometriosis is associated with LINC01133 upregulation, which may affect pathogenesis via the cellular proliferation and migration pathways

A cadaver‑based biomechanical model of acetabulum reaming for surgical virtual reality training simulators

Total hip arthroplasty (THA) is a highly successful surgical procedure, but complications remain, including aseptic loosening, early dislocation and misalignment. These may partly be related to lacking training opportunities for novices or those performing THA less frequently. A standardized training setting with realistic haptic feedback for THA does not exist to date. Virtual Reality (VR) may help establish THA training scenarios under standardized settings, morphology and material properties. This work summarizes the development and acquisition of mechanical properties on hip reaming, resulting in a tissue-based material model of the acetabulum for force feedback VR hip reaming simulators. With the given forces and torques occurring during the reaming, Cubic Hermite Spline interpolation seemed the most suitable approach to represent the nonlinear forcedisplacement behavior of the acetabular tissues over Cubic Splines. Further, Cubic Hermite Splines allowed for a rapid force feedback computation below the 1 ms hallmark. The Cubic Hermite Spline material model was implemented using a three-dimensional-sphere packing model. The resulting forces were delivered via a human–machine-interaction certified KUKA iiwa robotic arm used as a force feedback device. Consequently, this novel approach presents a concept to obtain mechanical data from high-force surgical interventions as baseline data for material models and biomechanical considerations; this will allow THA surgeons to train with a variety of machining hardness levels of acetabula for haptic VR acetabulum reaming

Consumer-oriented interventions to extend smartphones’ service lifetime

A promising strategy to reduce smartphones' environmental footprint is to increase their service lifetime, thereby reducing the demand for resource-intensive production of new devices. Most of the existing literature focuses on production-oriented measures, such as improving repairability, but what remains missing is a systematic overview of consumer-oriented interventions to extend smartphones' service lifetime. In this study, we applied the consumer intervention mapping approach by systematically identifying consumer decision situations along the smartphone life cycle and interventions that encourage consumers to make smartphone lifetime-extending decisions. We identify two main mechanisms to achieve lifetime extension: retention by increasing the time during which a user keeps a device, and recirculation by passing on a device to an additional user. Altogether, we identified 26 different types of interventions to induce consumers to make smartphone lifetime-extending decisions and structure these according to consumer-influence techniques, e.g., informing consumers about retention/recirculation options and environmental impacts caused throughout device life cycles, persuading consumers by creating emotional attachment, nudging consumers through product labels for secondhand devices, simplifying execution of lifetime-extending decision options through take-back programs, and incentivizing lifetime-extension through buy-back programs. These interventions' success in achieving lifetime extensions and reducing environmental impacts in practice depends on the degree to which they actually extend smartphones' service lifetime and reduce production of new devices (displacement rate), induction and re-spending effects associated with the interventions, and the interventions’ implementation feasibility, which conflicts of interest in the smartphone ecosystem often challenge