23 research outputs found

    SisÀilma ja tautitaakka : MissÀ mennÀÀn?

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    Tie- ja raideliikennemelun terveys- ja hyvinvointivaikutukset Kuopiossa ja JyvÀskylÀssÀ

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    Julkaisu oli 4.2.22 asti tuplana, kahtena tietueena. Toisen tietueen latausmÀÀrÀ tuolloin 489 kertaa. Poistetun URN yhdistyy nyt tÀhÀn tietueeseen

    Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

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    The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms regulating progress toward ÎČ cell failure, and factors determining time of presentation of clinical diabetes are poorly understood. We investigated changes in the serum metabolome prospectively in children who later progressed to type 1 diabetes. Serum metabolite profiles were compared between sample series drawn from 56 children who progressed to type 1 diabetes and 73 controls who remained nondiabetic and permanently autoantibody negative. Individuals who developed diabetes had reduced serum levels of succinic acid and phosphatidylcholine (PC) at birth, reduced levels of triglycerides and antioxidant ether phospholipids throughout the follow up, and increased levels of proinflammatory lysoPCs several months before seroconversion to autoantibody positivity. The lipid changes were not attributable to HLA-associated genetic risk. The appearance of insulin and glutamic acid decarboxylase autoantibodies was preceded by diminished ketoleucine and elevated glutamic acid. The metabolic profile was partially normalized after the seroconversion. Autoimmunity may thus be a relatively late response to the early metabolic disturbances. Recognition of these preautoimmune alterations may aid in studies of disease pathogenesis and may open a time window for novel type 1 diabetes prevention strategies

    Seksuaalinen hÀirintÀ kauneudenhoitoalalla : opintokokonaisuus

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    Seksuaalista hĂ€irintÀÀ esiintyy kaikilla työelĂ€mĂ€n osa-alueilla ja asia nousee aina ajoittain median otsikoihin. Tutkimusten mukaan hĂ€irintÀÀ on kokenut joka toinen 15–34 -vuotias nainen. Kauneudenhoitoalalla työskentelevĂ€t omasta ulkonÀöstÀÀn huolehtivat naiset ovat todennĂ€köinen hĂ€irinnĂ€n kohteeksi joutuva ryhmĂ€ ja tĂ€mĂ€n opinnĂ€ytetyön mielenkiinnon kohde. Seksuaalista hĂ€irintÀÀ esiintyy myös oppilaitoksissa. Useimmiten hĂ€irintĂ€ tapahtuu alaikĂ€isten kesken, harvemmin opettajan ja alaikĂ€isen vĂ€lillĂ€. Kouluissa hĂ€irintĂ€tapaukset paljastuvat yleensĂ€ helpommin kuin työpaikoilla. Oma tutkimus tehtiin Pinni lehden avustuksella. Lehden nettisivulla tehtyyn kyselyyn vastasi kesĂ€n 2012 aikana 74 henkilöÀ. KysymyksenĂ€ oli: ”Oletko joutunut seksuaalisen hĂ€irinnĂ€n kohteeksi asiakkaan, työkaverin tai esimiehen taholta?” Kyselyn tuloksena 53 % vastasi ”en lainkaan”, 42 % vastasi ”joskus” ja 5 % vastasi ”kyllĂ€, usein”. Tutkimuksen kvalitatiivinen osuus sisĂ€lsi haastattelujen lisĂ€ksi mahdollisuuden kertoa oma kokemuksensa vapaasti. Laadulliseen tutkimukseen saatiin 18 vastausta. NĂ€iden tutkimusten perusteella vahvistui kĂ€sitys siitĂ€, ettĂ€ kauneudenhoitoalalla esiintyy seksuaalista hĂ€irintÀÀ. Tutkimusaineiston analysoinnissa hyödynnettiin kattavan asiantuntijaverkoston tietoa ja erityisosaamista. Asiantuntijoina oli seksuaaliterapeutteja, seksuaalipedagogi, seksuaalineuvoja, kuraattoreita, terveydenhoitaja ja poliisi. LisĂ€ksi otettiin yhteys rikosuhripĂ€ivystykseen sekĂ€ juridiikan asiantuntijaan. OpinnĂ€ytetyön pÀÀmÀÀrĂ€nĂ€ oli tuottaa 2 opintoviikon mittainen opintokokonaisuus kehittĂ€mÀÀn erityisesti kauneudenhoitoalan terveystiedon opintoja. TĂ€mĂ€ opintokokonaisuus tukee nuorten seksuaalista hyvinvointia. Opintomateriaalissa kĂ€sitellÀÀn seksuaalisen hĂ€irinnĂ€n esiintymistapoja ja sen kohtaamista. LisĂ€ksi harjoitellaan kĂ€ytĂ€nnön toimintaohjeita seksuaalista hĂ€irintÀÀ kohdattaessa. OpinnĂ€ytetyön tarkoituksena on tuoda tĂ€rkeĂ€ asia esille ja nostaa valmiutta kohdata mahdollinen hĂ€irintĂ€ kauneudenhoitoalalla.Sexual harassment appears in every sector of working life and occasionally topic reaches media headlines. According to the researches every other 15-34 –year old woman has experienced sexual harassment. Women who work in beauty business take care of their appearance. They are likely victims to sexual harassment and main interest of this thesis. Sexual harassment appears also in educational institutions. Usually harassment takes place between students, rarely between teacher and student. Harassment cases are usually exposed more easily in schools than in workplaces. Research was done with assistance of the magazine Pinni. During summer 2012 74 people answered to the query in the magazine’s website. The question was: “Have you ever been the victim of sexual harassment by customer, co-worker or superior?” The query results: 53% answered “never”, 42% answered “sometimes” and 5% answered “yes, often”. In addition, the inquiryÂŽs qualitative part contained a possibility to freely share own experience about sexual harassment. This part was answered by 18 participants. The study strengthened perception that sexual harassment appears in beauty care. Knowledge and special expertise of comprehensive web of experts was needed to analyze results. Experts were sexual therapists, sexuality educator, sexual adviser, curators, health nurse and police. Criminal victim support and juridical expert was also contacted. Goal of the thesis was to produce study module which would develop health education especially in beauty care studies. This study module supports youthÂŽs sexual well-being. Study material deals with the forms of appearance of sexual harassment and how to face it. Practical guidance is also given. The purpose of the study module is to bring up this important thing and raise the preparedness to face possible harassment in beauty care
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