237 research outputs found
Doing mission inclusively
This article posits that Christians, while being in the world, are not of this world. This duality confronts them with the twofold need to be fully compliant with the demands of their faith and its calling to evangelise this world, on the one hand; and to live fully as fellow citizens of this world, and to cooperate with them in search of solutions for this worldâs challenges, on the other hand. Lessons are drawn from cultural anthropology theories to underscore dynamic processes of change, that start from non-threatening positions of working together inclusively, thus building trust, and advancing progressively, paving ways for dialogically sharing the Gospel. These developments are at the end argued and justified theologically, and then concluded with pragmatic examples drawn from live ministries born out of the co-authorâs initiatives
INTCAL98 radiocarbon age calibration, 24,000-0 cal BP
The focus of this paper is the conversion of radiocarbon ages to calibrated (cal) ages for the interval 24,000-0 cal BP (Before Present, 0 cal BP = AD 1950), based upon a sample set of dendrochronologically dated tree rings, uranium-thorium dated corals, and varve-counted marine sediment. The (14)C age-cal age information, produced by many laboratories, is converted to Delta(14)C profiles and calibration curves, for the atmosphere as well as the oceans. We discuss offsets in measured (14)C ages and the errors therein, regional (14)C age differences, tree-coral (14)C age comparisons and the time dependence of marine reservoir ages, and evaluate decadal vs. single-year (14)C results. Changes in oceanic deepwater circulation, especially for the 16,000-11,000 cal sp interval, are reflected in the Delta(14)C values of INTCAL98
IntCal09 and Marine09 radiocarbon age calibration curves, 0-50,000yeats cal BP
The IntCal04 and Marine04 radiocarbon calibration curves have been updated from 12 cal kBP (cal kBP is here defined as thousands of calibrated years before AD 1950), and extended to 50 cal kBP, utilizing newly available data sets that meet the IntCal Working Group criteria for pristine corals and other carbonates and for quantification of uncertainty in both the 14C and calendar timescales as established in 2002. No change was made to the curves from 0â12 cal kBP. The curves were constructed using a Markov chain Monte Carlo (MCMC) implementation of the random walk model used for IntCal04 and Marine04. The new curves were ratified at the 20th International Radiocarbon Conference in June 2009 and are available in the Supplemental Material at www.radiocarbon.org
NotCal04; comparison/ calibration 14C records 26-50 cal kyr BP
Author Posting. © Arizona Board of Regents on behalf of the University of Arizona, 2004. This article is posted here by permission of Dept. of Geosciences, University of Arizona for personal use, not for redistribution. The definitive version was published in Radiocarbon 46 (2004): 1225-1238.The radiocarbon calibration curve IntCal04 extends back to 26 cal kyr BP. While several high-resolution
records exist beyond this limit, these data sets exhibit discrepancies of up to several millennia. As a result, no calibration curve
for the time range 26â50 cal kyr BP can be recommended as yet, but in this paper the IntCal04 working group compares the
available data sets and offers a discussion of the information that they hold
In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae
Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is a Gram-negative bacterium that represents the main cause of porcine pleuropneumonia in pigs, causing significant economic losses to the livestock industry worldwide. A. pleuropneumoniae, as the majority of Gram-negative bacteria, excrete vesicles from its outer membrane (OM), accordingly defined as outer membrane vesicles (OMVs). Thanks to their antigenic similarity to the OM, OMVs have emerged as a promising tool in vaccinology. In this study we describe the in vivo testing of several vaccine prototypes for the prevention of infection by all known A. pleuropneumoniae serotypes. Previously identified vaccine candidates, the recombinant proteins ApfA and VacJ, administered individually or in various combinations with the OMVs, were employed as vaccination strategies. Our data show that the addition of the OMVs in the vaccine formulations significantly increased the specific IgG titer against both ApfA and VacJ in the immunized animals, confirming the previously postulated potential of the OMVs as adjuvant. Unfortunately, the antibody response raised did not translate into an effective protection against A. pleuropneumoniae infection, as none of the immunized groups following challenge showed a significantly lower degree of lesions than the controls. Interestingly, quite the opposite was true, as the animals with the highest IgG titers were also the ones bearing the most extensive lesions in their lungs. These results shed new light on A. pleuropneumoniae pathogenicity, suggesting that antibody-mediated cytotoxicity from the host immune response may play a central role in the development of the lesions typically associated with A. pleuropneumoniae infections
Can Urban Air Mobility become reality? Opportunities, challenges and selected research results
Urban Air Mobility (UAM) is a new air transportation system for passengers
and cargo in urban environments, enabled by new technologies and integrated
into multimodal transportation systems. The vision of UAM comprises the mass
use in urban and suburban environments, complementing existing transportation
systems and contributing to the decarbonization of the transport sector.
Initial attempts to create a market for urban air transportation in the last
century failed due to lack of profitability and community acceptance.
Technological advances in numerous fields over the past few decades have led to
a renewed interest in urban air transportation. UAM is expected to benefit
users and to also have a positive impact on the economy by creating new markets
and employment opportunities for manufacturing and operation of UAM vehicles
and the construction of related ground infrastructure. However, there are also
concerns about noise, safety and security, privacy and environmental impacts.
Therefore, the UAM system needs to be designed carefully to become safe,
affordable, accessible, environmentally friendly, economically viable and thus
sustainable. This paper provides an overview of selected key research topics
related to UAM and how the German Aerospace Center (DLR) contributed to this
research in the project "HorizonUAM - Urban Air Mobility Research at the German
Aerospace Center (DLR)". Selected research results that support the realization
of the UAM vision are briefly presented.Comment: 20 pages, 7 figures, project HorizonUA
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