Employing electro-mechanical analogies for co-resonantly coupled cantilever sensors

Understanding the behaviour of mechanical systems can be facilitated and improved by employing electro-mechanical analogies. These analogies enable the use of network analysis tools as well as purely analytical treatment of the mechanical system translated into an electric circuit. Recently, we developed a novel kind of sensor set-up based on two coupled cantilever beams with matched resonance frequencies (co-resonant coupling) and possible applications in magnetic force microscopy and cantilever magnetometry. In order to analyse the sensor's behaviour in detail, we describe it as an electric circuit model. Starting from a simplified coupled harmonic oscillator model with neglected damping, we gradually increase the complexity of the system by adding damping and interaction elements. For each stage, various features of the coupled system are discussed and compared to measured data obtained with a co-resonant sensor. Furthermore, we show that the circuit model can be used to derive sensor parameters which are essential for the evaluation of measured data. Finally, the much more complex circuit representation of a bending beam is discussed, revealing that the simplified circuit model of a coupled harmonic oscillator is a very good representation of the sensor system

Signal enhancement in cantilever magnetometry based on a co-resonantly coupled sensor

Cantilever magnetometry is a measurement technique used to study magnetic nanoparticles. With decreasing sample size, the signal strength is significantly reduced, requiring advances of the technique. Ultrathin and slender cantilevers can address this challenge but lead to increased complexity of detection. We present an approach based on the co-resonant coupling of a micro- and a nanometer-sized cantilever. Via matching of the resonance frequencies of the two subsystems we induce a strong interplay between the oscillations of the two cantilevers, allowing for a detection of interactions between the sensitive nanocantilever and external influences in the amplitude response curve of the microcantilever. In our magnetometry experiment we used an iron-filled carbon nanotube acting simultaneously as nanocantilever and magnetic sample. Measurements revealed an enhancement of the commonly used frequency shift signal by five orders of magnitude compared to conventional cantilever magnetometry experiments with similar nanomagnets. With this experiment we do not only demonstrate the functionality of our sensor design but also its potential for very sensitive magnetometry measurements while maintaining a facile oscillation detection with a conventional microcantilever setup

Magnetic properties of individual Co2FeGa Heusler nanoparticles studied at room temperature by a highly sensitive co-resonant cantilever sensor

The investigation of properties of nanoparticles is an important task to pave the way for progress and new applications in many fields of research like biotechnology, medicine and magnetic storage techniques. The study of nanoparticles with ever decreasing size is a challenge for commonly employed methods and techniques. It requires increasingly complex measurement setups, often low temperatures and a size reduction of the respective sensors to achieve the necessary sensitivity and resolution. Here, we present results on how magnetic properties of individual nanoparticles can be measured at room temperature and with a conventional scanning force microscopy setup combined with a co-resonant cantilever magnetometry approach. We investigate individual Co2FeGa Heusler nanoparticles with diameters of the order of 35 nm encapsulated in carbon nanotubes. We observed, for the first time, magnetic switching of these nanoparticles in an external magnetic field by simple laser deflection detection. Furthermore, we were able to deduce magnetic properties of these nanoparticles which are in good agreement with previous results obtained with large nanoparticle ensembles in other experiments. In order to do this, we expand the analytical description of the frequency shift signal in cantilever magnetometry to a more general formulation, taking unaligned sensor oscillation directions with respect to the magnetic field into account

Localized actuation of temperature responsive hydrogel-layers with a PCB-based micro-heater array

Space-resolved stimulation of active hydrogel layers can be achieved for example by using a micro-heater array. In the current work, we present the interaction of (i) such a rigid array of heating elements that can be selectively activated and (ii) an active thermo-responsive hydrogel layer that responds to the local stimulus change. Due to the respective local actuation, (iii) the surface form of a passive top-layer can be manipulated. We present continuum-based simulative predictions based on the Temperature Expansion Model and compare them to experimental outcomes for the system

Magnetization Dynamics of an Individual Single-Crystalline Fe-Filled Carbon Nanotube

The magnetization dynamics of individual Fe-filled multiwall carbon-nanotubes (FeCNT), grown by chemical vapor deposition, are investigated by microresonator ferromagnetic resonance (FMR) and Brillouin light scattering (BLS) microscopy and corroborated by micromagnetic simulations. Currently, only static magnetometry measurements are available. They suggest that the FeCNTs consist of a single-crystalline Fe nanowire throughout the length. The number and structure of the FMR lines and the abrupt decay of the spin-wave transport seen in BLS indicate, however, that the Fe filling is not a single straight piece along the length. Therefore, a stepwise cutting procedure is applied in order to investigate the evolution of the ferromagnetic resonance lines as a function of the nanowire length. The results show that the FeCNT is indeed not homogeneous along the full length but is built from 300 to 400 nm long single-crystalline segments. These segments consist of magnetically high quality Fe nanowires with almost the bulk values of Fe and with a similar small damping in relation to thin films, promoting FeCNTs as appealing candidates for spin-wave transport in magnonic applications. © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei

A compact integrated device for spatially selective optogenetic neural stimulation based on the Utah Optrode Array

Optogenetics is a powerful tool for neural control, but controlled light delivery beyond the superficial structures of the brain remains a challenge. For this, we have developed an optrode array, which can be used for optogenetic stimulation of the deep layers of the cortex. The device consists of a 10×10 array of penetrating optical waveguides, which are predefined using BOROFLOAT® wafer dicing. A wet etch step is then used to achieve the desired final optrode dimensions, followed by heat treatment to smoothen the edges and the surface. The major challenge that we have addressed is delivering light through individual waveguides in a controlled and efficient fashion. Simply coupling the waveguides in the optrode array to a separately-fabricated μLED array leads to low coupling efficiency and significant light scattering in the optrode backplane and crosstalk to adjacent optrodes due to the large mismatch between the μLED and waveguide numerical aperture and the working distance between them. We mitigate stray light by reducing the thickness of the glass backplane and adding a silicon interposer layer with optical vias connecting the μLEDs to the optrodes. The interposer additionally provides mechanical stability required by very thin backplanes, while restricting the unwanted spread of light. Initial testing of light output from the optrodes confirms intensity levels sufficient for optogenetic neural activation. These results pave the way for future work, which will focus on optimization of light coupling and adding recording electrodes to each optrode shank to create a bidirectional optoelectronic interface

In vivo optogenetics using a Utah Optrode Array with enhanced light output and spatial selectivity

Objective. Optogenetics allows the manipulation of neural circuits in vivo with high spatial and temporal precision. However, combining this precision with control over a significant portion of the brain is technologically challenging (especially in larger animal models). Approach. Here, we have developed, optimised, and tested in vivo, the Utah Optrode Array (UOA), an electrically addressable array of optical needles and interstitial sites illuminated by 181 μLEDs and used to optogenetically stimulate the brain. The device is specifically designed for non-human primate studies. Main results. Thinning the combined μLED and needle backplane of the device from 300 μm to 230 μm improved the efficiency of light delivery to tissue by 80%, allowing lower μLED drive currents, which improved power management and thermal performance. The spatial selectivity of each site was also improved by integrating an optical interposer to reduce stray light emission. These improvements were achieved using an innovative fabrication method to create an anodically bonded glass/silicon substrate with through-silicon vias etched, forming an optical interposer. Optical modelling was used to demonstrate that the tip structure of the device had a major influence on the illumination pattern. The thermal performance was evaluated through a combination of modelling and experiment, in order to ensure that cortical tissue temperatures did not rise by more than 1 °C. The device was tested in vivo in the visual cortex of macaque expressing ChR2-tdTomato in cortical neurons. Significance. It was shown that the UOA produced the strongest optogenetic response in the region surrounding the needle tips, and that the extent of the optogenetic response matched the predicted illumination profile based on optical modelling—demonstrating the improved spatial selectivity resulting from the optical interposer approach. Furthermore, different needle illumination sites generated different patterns of low-frequency potential activity

Multisite microLED optrode array for neural interfacing

We present an electrically addressable optrode array capable of delivering light to 181 sites in the brain, each providing sufficient light to optogenetically excite thousands of neurons in vivo, developed with the aim to allow behavioral studies in large mammals. The device is a glass microneedle array directly integrated with a custom fabricated microLED device, which delivers light to 100 needle tips and 81 interstitial surface sites, giving two-level optogenetic excitation of neurons in vivo. Light delivery and thermal properties are evaluated, with the device capable of peak irradiances >80  mW  /  mm2 per needle site. The device consists of an array of 181 80  μm  ×  80  μm2 microLEDs, fabricated on a 150-μm-thick GaN-on-sapphire wafer, coupled to a glass needle array on a 150-μm thick backplane. A pinhole layer is patterned on the sapphire side of the microLED array to reduce stray light. Future designs are explored through optical and thermal modeling and benchmarked against the current device

Experience with short-period, small gap undulators at the SwissFEL aramis beamline

The SwissFEL Aramis beamline provides hard X-ray FEL radiation down to 1 Angström with 5.8 GeV and short period, 15mm, in-vacuum undulators (U15). To reach the maximum designed K-value of 1.8 the U15s have to be operated with vacuum gaps down to 3.0 mm. The thirteen-undulator modules are 4m long and each of them is equipped with a pair of permanent magnet quadrupoles at the two ends, aligned magnetically to the undulator axis. Optical systems and dedicated photon diagnostics are used to check the alignment and improve the K-value calibration. In this talk the main steps of the undulator commissioning will be recalled and a systematic comparison between the magnetic results and the electron and photon based measurements will be reported to highlight achievements and open issues.peer-reviewe