Pulse or hyaline ring granuloma. Review of the literature on etiopathogenesis of oral and extraoral lesions

Since the late 1950s, reports on an unusual giant-cell granulomatous lesion affecting the jaws, lungs, stomach and intestines have been published. Histopathologically, the lesions showed the presence of structureless hyaline rings with multinucleated giant cells. The aim of this review was to summarize the literature on the etiopathogenesis of the so-called oral and extraoral pulse or hyaline ring granuloma. Literature was searched using PubMed and Medline. In addition, hand search was performed. Search words were oral and extraoral hyaline ring granuloma, giant-cell hyaline angiopathy, pulse granuloma and chronic periostitis. Numerous terms for hyaline ring granuloma have been introduced over time (1971-2008). One hundred seventy-three cases of oral hyaline ring granuloma have been retrieved from the literature. In the mandible, 72.3% occurred . Two theories for etiopathogenesis have been proposed: (1) the origin of the hyaline rings is due to a foreign material (pulse and legumes) having penetrated the oral mucosa or gastrointestinal tract and lungs (exogenous theory) and (2) the rings are due to hyaline degenerative changes in walls of blood vessels (endogenous theory). Experimental production of oral and extraoral hyaline ring granulomas is consistent with the exogenous origin. Particles or remains of leguminous cells having been implanted or aspirated into human tissues whether located to the oral cavity or throughout the entire digestive tract and respiratory system are thought to be causative. Pulse or hyaline ring granulomas are rare but are well-defined oral and extraoral lesions due to implantation of the cellulose moiety of plant foods in contrast to the starch components

Implants in patients with oral manifestations of autoimmune or muco-cutaneous diseases : a systematic review

To give an overview on implant survival rates in patients with oral manifestations of systemic autoimmune (oral Lichen planus (oLp), Pemphigus (Pe)), muco-cutaneous (Epidermolysis bullosa (EB)), autoimmune multisystemic rheumatic diseases (Sjögren´s syndrome (SjS), systemic Lupus erythematosus (sLE), or systemic Sclerosis (sSc)). Systematic literature review (PubMed/Medline, Embase) using MESH and search term combinations, published between 1980 and August 2018 in English language reporting on dental implant-prosthetic rehabilitation of patients with oLp, Pe, EB, SjS, sLE, sSc, study design, age, gender, follow-up period (? 12 months), implant survival rate. Implant-related weighed mean values of implant survival rate (wmSR) were calculated. After a mean follow-up period (mfp) of 44.6 months, a wmSR of 98.3 % was calculated from data published for patients with oLp (100 patients with 302 implants). Data of 27 patients (152 implants) with EB revealed wmSR of 98.7 % following mfp of 32.6 months. For 71 patients (272 implants) with SjS, wmSR was 94.2 % following a mfp of 45.2 months, and for 6 patients (44 implants) with sSc, wmSR was 97.7 % after mfp of 37.5 months. One case report on one patient each with Pe (two implants) as well as sLE (6 implants) showed 100 % SR following at least 24 months. Guidelines regarding implant treatment of patients with oLp, Pe, EB, SjS, sLE or sSc do not exist nor are contraindicating conditions defined. Implant survival rates of patients affected are comparable to those of healthy patients. For implant-prosthetic rehabilitation of patients with Pe and sLE no conclusions can be drawn due to lack of sufficient clinical data. Implant-prosthetic treatment guidelines regarding healthy patients should be strictly followed, but frequent recall is recommended in patients affected with oLp, SjS, EB, SSc, Pe or sLE

Large Impacts around a Solar Analog Star in the Era of Terrestrial Planet Formation

The final assembly of terrestrial planets occurs via massive collisions, which can launch copious clouds of dust that are warmed by the star and glow in the infrared. We report the real-time detection of a debris-producing impact in the terrestrial planet zone around a 35-million year-old solar analog star. We observed a substantial brightening of the debris disk at 3-5 {\mu}m, followed by a decay over a year, with quasi-periodic modulations of the disk flux. The behavior is consistent with the occurrence of a violent impact that produced vapor out of which a thick cloud of silicate spherules condensed that were ground into dust by collisions. These results demonstrate how the time domain can become a new dimension for the study of terrestrial planet formation.Comment: 25 pages, 7 figures (fixed a typo in name

The Rapidly Flaring Afterglow of the Very Bright and Energetic GRB 070125

We report on multi-wavelength observations, ranging from the X-ray to radio wave bands, of the IPN-localized gamma-ray burst GRB 070125. Spectroscopic observations reveal the presence of absorption lines due to O I, Si II, and C IV, implying a likely redshift of z = 1.547. The well-sampled light curves, in particular from 0.5 to 4 days after the burst, suggest a jet break at 3.7 days, corresponding to a jet opening angle of ~7.0 degrees, and implying an intrinsic GRB energy in the 1 - 10,000 keV band of around E = (6.3 - 6.9)x 10^(51) erg (based on the fluences measured by the gamma-ray detectors of the IPN network). GRB 070125 is among the brightest afterglows observed to date. The spectral energy distribution implies a host extinction of Av < 0.9 mag. Two rebrightening episodes are observed, one with excellent time coverage, showing an increase in flux of 56% in ~8000 seconds. The evolution of the afterglow light curve is achromatic at all times. Late-time observations of the afterglow do not show evidence for emission from an underlying host galaxy or supernova. Any host galaxy would be subluminous, consistent with current GRB host-galaxy samples. Evidence for strong Mg II absorption features is not found, which is perhaps surprising in view of the relatively high redshift of this burst and the high likelihood for such features along GRB-selected lines of sight.Comment: 50 pages, 9 figures, 5 tables Accepted to the Astrophysical Journa

The XMM Cluster Survey: Forecasting cosmological and cluster scaling-relation parameter constraints

We forecast the constraints on the values of sigma_8, Omega_m, and cluster scaling relation parameters which we expect to obtain from the XMM Cluster Survey (XCS). We assume a flat Lambda-CDM Universe and perform a Monte Carlo Markov Chain analysis of the evolution of the number density of galaxy clusters that takes into account a detailed simulated selection function. Comparing our current observed number of clusters shows good agreement with predictions. We determine the expected degradation of the constraints as a result of self-calibrating the luminosity-temperature relation (with scatter), including temperature measurement errors, and relying on photometric methods for the estimation of galaxy cluster redshifts. We examine the effects of systematic errors in scaling relation and measurement error assumptions. Using only (T,z) self-calibration, we expect to measure Omega_m to +-0.03 (and Omega_Lambda to the same accuracy assuming flatness), and sigma_8 to +-0.05, also constraining the normalization and slope of the luminosity-temperature relation to +-6 and +-13 per cent (at 1sigma) respectively in the process. Self-calibration fails to jointly constrain the scatter and redshift evolution of the luminosity-temperature relation significantly. Additional archival and/or follow-up data will improve on this. We do not expect measurement errors or imperfect knowledge of their distribution to degrade constraints significantly. Scaling-relation systematics can easily lead to cosmological constraints 2sigma or more away from the fiducial model. Our treatment is the first exact treatment to this level of detail, and introduces a new `smoothed ML' estimate of expected constraints.Comment: 28 pages, 17 figures. Revised version, as accepted for publication in MNRAS. High-resolution figures available at http://xcs-home.org (under "Publications"

THE FIRST MAXIMUM-LIGHT ULTRAVIOLET THROUGH NEAR-INFRARED SPECTRUM OF A TYPE Ia SUPERNOVA

We present the first maximum-light ultraviolet (UV) through near-infrared (NIR) Type Ia supernova (SN Ia) spectrum. This spectrum of SN 2011iv was obtained nearly simultaneously by the Hubble Space Telescope at UV/optical wavelengths and the Magellan Baade telescope at NIR wavelengths. These data provide the opportunity to examine the entire maximum-light SN Ia spectral energy distribution. Since the UV region of an SN Ia spectrum is extremely sensitive to the composition of the outer layers of the explosion, which are transparent at longer wavelengths, this unprecedented spectrum can provide strong constraints on the composition of the SN ejecta, and similarly the SN explosion and progenitor system. SN 2011iv is spectroscopically normal, but has a relatively fast decline (Δm [subscript 15](B) = 1.69 ± 0.05 mag). We compare SN 2011iv to other SNe Ia with UV spectra near maximum light and examine trends between UV spectral properties, light-curve shape, and ejecta velocity. We tentatively find that SNe with similar light-curve shapes but different ejecta velocities have similar UV spectra, while those with similar ejecta velocities but different light-curve shapes have very different UV spectra. Through a comparison with explosion models, we find that both a solar-metallicity W7 and a zero-metallicity delayed-detonation model provide a reasonable fit to the spectrum of SN 2011iv from the UV to the NIR

GRB Afterglows and Other Transients in the SDSS

The Sloan Digital Sky Survey (SDSS) will image one quarter of the sky centered on the northern galactic cap and produce a 3‐D map of galaxies and quasars found in the sample. An additional 225 deg2 southern survey will be imaged repeatedly on varying timescales. Here we discuss both archival searches in the SDSS catalog (such as SDSS J24602.54+011318.8) and active searches with the SDSS instruments (such as for GRB 010222) for GRB afterglows and other transient objects. © 2003 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87288/2/349_1.pd

Supernova 2018cuf : a type iip supernova with a slow fall from plateau

We present multiband photometry and spectroscopy of SN 2018cuf, a Type IIP ("P"for plateau) supernova (SN) discovered by the Distance Less Than 40 Mpc Survey within 24 hr of explosion. SN 2018cuf appears to be a typical SN IIP, with an absolute V-band magnitude of -16.73 ± 0.32 at maximum and a decline rate of 0.21 ± 0.05 mag/50 days during the plateau phase. The distance of the object was constrained to be 41.8 ± 5.7 Mpc by using the expanding photosphere method. We used spectroscopic and photometric observations from the first year after the explosion to constrain the progenitor of SN 2018cuf using both hydrodynamic light-curve modeling and late-time spectroscopic modeling. The progenitor of SN 2018cuf was most likely a red supergiant of about 14.5 Me that produced 0.04 ± 0.01 Me 56Ni during the explosion. We also found ∼0.07 Me of circumstellar material (CSM) around the progenitor is needed to fit the early light curves, where the CSM may originate from presupernova outbursts. During the plateau phase, high-velocity features at ∼11,000 km s-1 were detected in both the optical and near-infrared spectra, supporting the possibility that the ejecta were interacting with some CSM. A very shallow slope during the postplateau phase was also observed, and it is likely due to a low degree of nickel mixing or the relatively high nickel mass in the SN.Fil: Dong, Yize. University of California at Davis; Estados UnidosFil: Valenti, S.. University of California at Davis; Estados UnidosFil: Bostroem, K. A.. University of California at Davis; Estados UnidosFil: Sand, D. J.. University of Arizona; Estados UnidosFil: Andrews, Jennifer E.. University of Arizona; Estados UnidosFil: Galbany, Lluís. Universidad de Granada; EspañaFil: Jha, Saurabh W.. State University of New Jersey; Estados UnidosFil: Eweis, Youssef. State University of New Jersey; Estados UnidosFil: Kwok, Lindsey. State University of New Jersey; Estados UnidosFil: Hsiao, Eric. Florida State University; Estados UnidosFil: Davis, Scott. Florida State University; Estados UnidosFil: Brown, Peter J.. Texas A&M University; Estados UnidosFil: Kuncarayakti, H.. University of Turku; FinlandiaFil: Maeda, Keiichi. Kyoto University; JapónFil: Rho, Jeonghee. SETI Institute; Estados UnidosFil: Amaro, R. C.. University of Arizona; Estados UnidosFil: Anderson, J. P.. European Southern Observatory Chile; ChileFil: Arcavi, Iair. Universitat Tel Aviv; IsraelFil: Burke, Jamison. University of California; Estados UnidosFil: Dastidar, Raya. Aryabhatta Research Institute of observational sciences; IndiaFil: Folatelli, Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica La Plata; ArgentinaFil: Haislip, Joshua. University of North Carolina at Chapel Hill; Estados UnidosFil: Hiramatsu, Daichi. University of California; Estados UnidosFil: Hosseinzadeh, Griffin. Harvard-Smithsonian Center for Astrophysics; Estados UnidosFil: Howell, D. Andrew. University of California; Estados UnidosFil: Jencson, J.. University of Arizona; Estados UnidosFil: Kouprianov, Vladimir. University of North Carolina at Chapel Hill; Estados UnidosFil: Lundquist, M.. University of Arizona; Estados UnidosFil: Lyman, J. D.. University of Warwick; Reino UnidoFil: McCully, Curtis. University of California; Estados Unido

Uncoordinated Transcription and Compromised Muscle Function in the Lmna-Null Mouse Model of Emery-Dreifuss Muscular Dystrophy

LMNA encodes both lamin A and C: major components of the nuclear lamina. Mutations in LMNA underlie a range of tissue-specific degenerative diseases, including those that affect skeletal muscle, such as autosomal-Emery-Dreifuss muscular dystrophy (A-EDMD) and limb girdle muscular dystrophy 1B. Here, we examine the morphology and transcriptional activity of myonuclei, the structure of the myotendinous junction and the muscle contraction dynamics in the lmna-null mouse model of A-EDMD. We found that there were fewer myonuclei in lmna-null mice, of which ∼50% had morphological abnormalities. Assaying transcriptional activity by examining acetylated histone H3 and PABPN1 levels indicated that there was a lack of coordinated transcription between myonuclei lacking lamin A/C. Myonuclei with abnormal morphology and transcriptional activity were distributed along the length of the myofibre, but accumulated at the myotendinous junction. Indeed, in addition to the presence of abnormal myonuclei, the structure of the myotendinous junction was perturbed, with disorganised sarcomeres and reduced interdigitation with the tendon, together with lipid and collagen deposition. Functionally, muscle contraction became severely affected within weeks of birth, with specific force generation dropping as low as ∼65% and ∼27% of control values in the extensor digitorum longus and soleus muscles respectively. These observations illustrate the importance of lamin A/C for correct myonuclear function, which likely acts synergistically with myotendinous junction disorganisation in the development of A-EDMD, and the consequential reduction in force generation and muscle wasting