Assessing antioxidant activity of tea extracts and some of chemicals using voltammetry and potentiometry

The comparison of antioxidant activity of tea extracts and some chemicals was conducted by independent methods: voltammetry and potentiometry. Except for few cases, we showed satisfactory agreement between test substances activity rows obtained by two different methods. Mechanisms of antioxidative action were proposed. Presumably, sample components are involved in competing reactions like reduction-oxidation and complexation reactions. Limitations and advantages of both methods were defined

Simple Synthesis of Pyrazole-derived Dithioethers

A number of pyrazole-derived dithioethers were prepared by the reaction of diisothiuronium salts and 2-(3,5-dimethylpyrazol-1-yl)ethanol tosylate in a basic aqueous solution. Diisothiuronium salts were prepared by the reaction of thiourea with alpha,omega-dibromoalkanes containing from two to nine methylene groups. The use of these salts allowed in situ generation ions dithiolate, thus eliminating the need to use hazardous dimercaptans

Assessing antioxidant activity of tea extracts and some of chemicals using voltammetry and potentiometry

The comparison of antioxidant activity of tea extracts and some chemicals was conducted by independent methods: voltammetry and potentiometry. Except for few cases, we showed satisfactory agreement between test substances activity rows obtained by two different methods. Mechanisms of antioxidative action were proposed. Presumably, sample components are involved in competing reactions like reduction-oxidation and complexation reactions. Limitations and advantages of both methods were defined

Entscheidungen der Gerichte und Verwaltungsbehörden aus dem Rechtsgebiete der inneren Verwaltung.

Vol. 19-27 bearb. unter mitwerkung...J. Henle; v. 29 bearb. unter mitwerkung...R. Oeschey.Vol. 11-20 called Band 1-10 der neuen Folge.Editors: v. 1-37, 1881-1917, Anton Reger; v. 38- 1918- Rudolf Oeschey.Minor variations in publisher.Imprint varies: v. 1-9, 1881-1889, Nördlingen.Supplemented by Ergänzungsband ... München : C.H. Beck, 1891- ; Editors v. 1-4 1891-1911, Anton Reger; v. 5- 1921- Rudolf Oeschey.Mode of access: Internet.Title varies: v. 1-10, 1881-1890, Entscheidungen der Gerichte und Verwaltungsbehörden aus dem Gebiete des auf Rechtsgesetzlichen und Gemeinrechtlichen bestimmungen beruhenden Verwaltungs- und Polizeistrafrechtes; v. 11-43, 1891-1923, Entscheidungen der Gerichte und Verwaltungsbehörden aus dem Gebiete des auf Reichsgesetzlichen und Gemeinrechtlichen bestimmungen beruhenden Verwaltungs- und Polizeistrafrechtes (Einschliesslich des gesamten Arbeiter-Versicherungsrechts); v. 44 (1924)- Entscheidungen der Gerichte und Verwaltungsbehörden aus dem Rechtsgebiete der inneren Verwaltung

Combustion synthesis of sialon and nitride phases based on ferrosilicoaluminum with marshalite additives

The effect of a marshalite additive on nitriding of a complex ferrosilicoaluminum (FSA) ferroalloy to produce a sialon-based composite by self-propagating high-temperature synthesis is studied. The phase composition of the combustion products is revealed by changing the percentage of the marshalite additive in the starting reaction mixture. The optimal ratio of the marshalite additive to the initial FSApowder to obtain a product with the maximum sialon content is established

Changes in CSF Surface Tension in Relation to Surfactant Proteins in Children with Intraventricular Hemorrhage

The regulation of surface tension (ST) by surfactants plays an important role in the human respiratory system but is largely unexplored in brain homeostasis. The aim of this study was to evaluate changes in ST in relation to surfactant proteins (SPs) in children with intraventricular hemorrhage (IVH). CSF samples from 93 patients were analyzed for ST with a force tensiometer and SP-A-D and -G with ELISA assays. Patients belonged to six groups: (i) IVH before primary intervention (PI), (ii) IVH 4–28 days after PI, (iii) IVH 44–357 days after PI, (iv) hydrocephalus, (v) sepsis and (vi) controls. We found indirect correlations and significant differences in ST and SPs (all p < 0.001; except for SP-C, p = 0.007). Post hoc analyses showed significantly decreased ST in IVH patients before PI compared with patients with hydrocephalus, sepsis or controls (p < 0.001), but it increased in IVH patients over time. All SPs were significantly elevated when comparing IVH patients before PI with controls (all p < 0.001; except for SP-C, p = 0.003). Children suffering from IVH displayed an increase in SPs and a decrease in ST as coping mechanisms to preserve CSF flow. The increase in ST over time could serve as prognostic marker for the healing process

Changes in CSF Surface Tension in Relation to Surfactant Proteins in Children with Intraventricular Hemorrhage

The regulation of surface tension (ST) by surfactants plays an important role in the human respiratory system but is largely unexplored in brain homeostasis. The aim of this study was to evaluate changes in ST in relation to surfactant proteins (SPs) in children with intraventricular hemorrhage (IVH). CSF samples from 93 patients were analyzed for ST with a force tensiometer and SP-A-D and -G with ELISA assays. Patients belonged to six groups: (i) IVH before primary intervention (PI), (ii) IVH 4–28 days after PI, (iii) IVH 44–357 days after PI, (iv) hydrocephalus, (v) sepsis and (vi) controls. We found indirect correlations and significant differences in ST and SPs (all p < 0.001; except for SP-C, p = 0.007). Post hoc analyses showed significantly decreased ST in IVH patients before PI compared with patients with hydrocephalus, sepsis or controls (p < 0.001), but it increased in IVH patients over time. All SPs were significantly elevated when comparing IVH patients before PI with controls (all p < 0.001; except for SP-C, p = 0.003). Children suffering from IVH displayed an increase in SPs and a decrease in ST as coping mechanisms to preserve CSF flow. The increase in ST over time could serve as prognostic marker for the healing process

Changes in CSF Surface Tension in Relation to Surfactant Proteins in Children with Intraventricular Hemorrhage

The regulation of surface tension (ST) by surfactants plays an important role in the human respiratory system but is largely unexplored in brain homeostasis. The aim of this study was to evaluate changes in ST in relation to surfactant proteins (SPs) in children with intraventricular hemorrhage (IVH). CSF samples from 93 patients were analyzed for ST with a force tensiometer and SP-A-D and -G with ELISA assays. Patients belonged to six groups: (i) IVH before primary intervention (PI), (ii) IVH 4–28 days after PI, (iii) IVH 44–357 days after PI, (iv) hydrocephalus, (v) sepsis and (vi) controls. We found indirect correlations and significant differences in ST and SPs (all p < 0.001; except for SP-C, p = 0.007). Post hoc analyses showed significantly decreased ST in IVH patients before PI compared with patients with hydrocephalus, sepsis or controls (p < 0.001), but it increased in IVH patients over time. All SPs were significantly elevated when comparing IVH patients before PI with controls (all p < 0.001; except for SP-C, p = 0.003). Children suffering from IVH displayed an increase in SPs and a decrease in ST as coping mechanisms to preserve CSF flow. The increase in ST over time could serve as prognostic marker for the healing process

Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

Variants in the high confident autism spectrum disorder (ASD) gene ANK2 target both ubiquitously expressed 220 kDa ankyrin-B and neurospecific 440 kDa ankyrin-B (AnkB440) isoforms. Previous work showed that knock-in mice expressing an ASD-linked Ank2 variant yielding a truncated AnkB440 product exhibit ectopic brain connectivity and behavioral abnormalities. Expression of this variant or loss of AnkB440 caused axonal hyperbranching in vitro, which implicated AnkB440 microtubule bundling activity in suppressing collateral branch formation. Leveraging multiple mouse models, cellular assays, and live microscopy, we show that AnkB440 also modulates axon collateral branching stochastically by reducing the number of F-actin-rich branch initiation points. Additionally, we show that AnkB440 enables growth cone (GC) collapse in response to chemorepellent factor semaphorin 3 A (Sema 3 A) by stabilizing its receptor complex L1 cell adhesion molecule/neuropilin-1. ASD-linked ANK2 variants failed to rescue Sema 3A-induced GC collapse. We propose that impaired response to repellent cues due to AnkB440 deficits leads to axonal targeting and branch pruning defects and may contribute to the pathogenicity of ANK2 variants