Gender konkret: Vier Beispiele aus der Balser Ausbildung von Lehrpersonen

In der Basler Ausbildung von Lehrpersonen werden Genderkompetenzen in verschiedenen Ausbildungsgängen geschult. In der Ausbildung von Lehrpersonen für die Sekundarstufe I und II gibt es seit rund fünf Jahren das Wahlpflichtfach geschlechterbewusste Pädagogik. Primarlehrpersonen erhalten in der Schlusspraxis einen verbindlichen, konkreten Genderauftrag. In Projektphase ist ein Nachdiplomstudium Laufbahnvorbereitung an der neuen Hochschule für Pädagogik und Soziale Arbeit beider Basel, in dem Gender und Interkulturelles als Querschnittthemen systematisch verbunden werden sollen. Inwiefern dieser Anspruch genereller Standard in den neuen Ausbildungsgängen sein wird, hängt davon ab, wie Gleichstellung als Qualitätsmerkmal verankert werden kann

Extended Nitric Oxide Measurements in Exhaled Air of Cystic Fibrosis and Healthy Adults

In cystic fibrosis (CF) lung disease, exhaled nitric oxide (FeNO) is not raised, but rather is normal or even decreased when measured at a single expiratory flow. FeNO measurements at several flow rates allow differentiation between alveolar and bronchial nitric oxide (NO) production. Extended FeNO measurements therefore should be useful to localize the FeNO deficit in CF airways. FeNO was measured in stable CF adults with moderate lung disease and in healthy controls. Bronchial NO fluxes (JNO,Br) and alveolar NO concentrations (CAlv) were calculated from FeNO measurements at flow rates of 100, 150 and 200ml/s using a method previously described. Thirty-two adults were included in the study, 12 of whom had CF. CF adults had significantly lower FeNO values at all flow rates. The median JNO,Br was significantly lower in CF adults than in healthy controls [0.31nl/s (range=0.11-0.63) vs. 0.70nl/s (0.27-3.52); P<0.001], while the median CAlv was similar in both groups [1.7ppb (0.3-3.9) vs. 1.2 (0.1-5.2)]. Pulmonary NO exchange did not differ significantly between subgroups of CF patients with and without chronic Pseudomonas aeruginosa infection. No significant correlation was detectable between FEV1/VC and JNO,Br and CAlv, respectively. Extended FeNO measurements can separate alveolar and bronchial NO outputs in CF adults. The lower FeNO in adults with moderate to severe CF lung disease is likely to be the result of lower bronchial NO outpu

What makes a social practice? Being, knowing, doing and leading

Despite several decades of work on social practice, many open intriguing questions remain about their existence and functions within an organizational context. In this article, we discuss the “inherent logics” of social practice—being, knowing, and doing—to depict the meaning and mainspring of its conservation within an organizational context. We argue that the understanding of social practice in organization and management studies has predominantly focused on the internal workings of social practice, and we propose that a contextualization of the inherent logics of social practice may be a next step in advancing theory and empirical research. We propose a contested coexistence of social practices in organizations and thereby argue that the conservation of social practice protrudes another element belonging to its inherent logics, i.e., leading. We suggest that leadership in distributed and adaptive organizations responds to innovation and competitive challenges with wisdom, care, and fluidity

Gemeinsam, aber nicht im Gleichschritt

Das Lernen in heterogenen Gruppen kann aus unterschiedlichen Perspektiven betrachtet werden: Im Beitrag richten wir den Fokus nicht auf grundlegend konzeptionelle oder organisatorische Aspekte, sondern auf die Gestaltung von Lernsituationen. Ausgehend von Praxisbeobachtungen fasst Faust-Siehl (2001, 202f) vier verschiedene Gestaltungsmöglichkeiten solcher Lernsituationen zusammen: selbst geleitetes, individuelles Arbeiten, themenbezogene "Kurse", Abteilungsunterricht innerhalb des Klassenverbands und gemeinsame Unterrichtssituationen. Über die Ausprägung der einzelnen Gestaltungsvarianten in der Praxis gibt es in der Literatur kaum Daten. Bei Roßbach (2007³, 80) lassen sich Angaben finden, aus denen mit aller Vorsicht geschlossen werden kann, dass das gemeinsame Lernen in heterogenen Lerngruppen (33%) seltener praktiziert wird als der Unterricht in jahrgangsbezogenen Abteilungen (44%). Nach Aussage von Faust-Siehl (2001) bereitet bei der Gestaltung gemeinsamer, differenzierter Lernsituationen "der üblicherweise lehrgangsmäßig aufgebaute Mathematikunterricht" (a. a. O., 206) die größten Schwierigkeiten

The Effect of Two Sock Fabrics on Physiological Parameters Associated with Blister Incidence: A Laboratory Study

The goal of the present study was to investigate physiological effects, mainly at the level of the foot, of two sock fabrics with distinct moisture properties. Twelve participants wore two different socks, one on each foot. The following two sock types were used: PP: 99.6% polypropylene and 0.4% elastane and BLEND: 50% Merino wool, 33% polypropylene, and 17% polyamide. The participants walked three times on a treadmill at 5 km h−1, with no gradient for the first and third phase and a 10% upward inclination for the second walking phase. The microclimate temperature between the boot and foot was measured during walking. Preceding and following the walking phases, additional measurements were carried out at the level of the foot, i.e. skin temperature and skin hydration on three locations and skin friction between the posterior surface of the calcaneus and a glass plate. In addition, the moisture absorption of boots and socks was determined. Differences between the sock fabrics were found for weight gain and microclimate temperature: (i) PP tended to hold less water compared to BLEND, (ii) the boot's microclimate temperature resulted in larger values for BLEND measured at the dorsal surface at the level of the third metatarsal, and (iii) warmer microclimates of the boot were measured for PP compared to BLEND at the distal anterior end of the tibia. The established differences in moisture behavior of both socks did not result in detectable differences in parameters measured on the skin of the foo

Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis

The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are arranged in small parallel bundles, each myotube spanning the forming muscles from end to end. This unique arrangement potentially assigns a crucial role to primary myotube end regions for muscle morphogenesis. We have cloned muscle ankyrin repeat protein (MARP) as a gene induced in adult rat skeletal muscle by denervation. MARP is the rodent homologue of human C-193 (Chu, W., D.K. Burns, R.A. Swerick, and D.H. Presky. 1995. J. Biol. Chem. 270:10236-10245) and is identical to rat cardiac ankyrin repeat protein. (Zou, Y., S. Evans, J. Chen, H.-C. Kuo, R.P. Harvey, and K.R. Chien. 1997. Development. 124:793-804). In denervated muscle fibers, MARP transcript accumulated in a unique perisynaptic pattern. MARP was also expressed in large blood vessels and in cardiac muscle, where it was further induced by cardiac hypertrophy. During embryonic development, MARP was expressed in forming skeletal muscle. In situ hybridization analysis in mouse embryos revealed that MARP transcript exclusively accumulates at the end regions of primary myotubes during muscle morphogenesis. This closely coincided with the expression of thrombospondin-4 in adjacent prospective tendon mesenchyme, suggesting that these two compartments may constitute a functional unit involved in muscle morphogenesis. Transfection experiments established that MARP protein accumulates in the nucleus and that the levels of both MARP mRNA and protein are controlled by rapid degradation mechanisms characteristic of regulatory early response genes. The results establish the existence of novel regulatory muscle fiber subcompartments associated with muscle morphogenesis and denervation and suggest that MARP may be a crucial nuclear cofactor in local signaling pathways from prospective tendon mesenchyme to forming muscle and from activated muscle interstitial cells to denervated muscle fibers

A novel germline mutation of PDGFR-β might be associated with clinical response of colorectal cancer to regorafenib

This is the first description of a germline mutation of the PDGFR-β gene, that correlates with response to regorafenib in a patient with metastatic colorectal cance

Cultivating Environmental Stewardship in the Suburbs

My project examines the concept of environmental stewardship from two angles: first, an examination of the body of philosophical thought on the concept of “responsibility towards future generations.” I use this context to develop my own philosophical framework by which we might gauge our actions as they relate to the environment, and its relative improvement or destruction. Starting from this framework, I then explore different ways people have tried, and are trying to encourage stewardship in the modern world. I examine and critique the value and efficacy of these different practices. Finally, I bring both the philosophical and the practical together to examine a real neighborhood in unincorporated Wheaton. Using demographic information, real estate information, and satellite imagery, I consider how a small community might transition to improve their footprint and potential for lasting without degradation for future generations