Investigating the accuracy of parallel analysis in underextraction conditions: A monte carlo study

One of the most important decisions to make when performing an exploratory factor analysis regards the number of factors to retain. Parallel analysis is considered to be the best course of action in these circumstances as it consistently outperforms other factor extraction methods (Zwick & Velicer, 1986). Even so, parallel analysis requires further research and refinement to improve its accuracy. Characteristics such as factor loadings, correlations between factors, and number of variables per factor all have been shown to adversely impact the effectiveness of parallel analysis as a means of identifying the number of factors. Critically, even the choice of criteria on which to evaluate factors such as the eigenvalue at the 50th or 95th percentile can have deleterious effects on the number of factors extracted. One area of parallel analysis yet to be researched is the magnitude of the difference between the actual eigenvalue and the random data-based eigenvalue. Currently, even if the margin between the actual eigenvalue and the random data-based eigenvalue is nominal, the factor is considered to be meaningful. As such, it may behoove researchers to enforce a higher standard, such as a greater margin between the two eigenvalues than just an absolute difference. Accordingly, the purpose of this study will be to evaluate the efficacy of a 10 percent margin criterion as compared to an absolute margin. These margins will specifically be evaluated in conjunction with the 50th, 90th, 95th, and 99th percentile eigenvalue criteria on a population correlation matrix which engenders underextraction. Previous research (Matsumoto & Brown, 2017) explored the same conditions on a population correlation matrix designed to cause overextraction. They found that the most stringent standard (99th percentile eigenvalue plus 10 percent margin) was the most accurate. For the present study however, we hypothesize that the most accurate results will be obtained from a standard less stringent than the 99th percentile eigenvalue plus 10 percent margin. This research has important implications for the scientific and practical application of psychometrics

Simple Synchronous Detector for Spectroscopic Studies

Lock-in-amplifiers are used in many applications for signal processing and offer the ability to discriminate high levels of noise. While these instruments are very powerful and offer many features, they are not portable and are expensive. An economical and easy to use alternative circuit is presented which incorporates pre-amplification, reference, and synchronous detection on one circuit board. The design can be used in laboratory or process control situations where its small size and low cost are advantageous. The circuit was successfully applied to moderate and high level signals as seen in flame infrared emission detection and in a portable radiometer for rocket plume studies

Naturally occurring sendai virus infection of athymic nude mice

Nude (nu/nu) mice, Balb/c derived, responded to a naturally occurring Sendai virus infection in a different manner than conventional mice. They developed a chronic debilitating disease and a persistent viral infection of the respiratory tract with intranuclear inclusion bodies in tracheal, bronchial and bronchiolar epithelial cells, laryngeal and tracheal glandular epithelium and in type I and II alveolar cells. The infection was identified by serologic and tissue culture studies, the mouse antibody production test and ultrastructural examination of pulmonary lesions. Phlebitis of pulmonary veins, suppurative rhinitis and otitis media accompanied the viral infection while some mice developed a secondary bronchopneumonia

Gene regulatory networks elucidating huanglongbing disease mechanisms.

Next-generation sequencing was exploited to gain deeper insight into the response to infection by Candidatus liberibacter asiaticus (CaLas), especially the immune disregulation and metabolic dysfunction caused by source-sink disruption. Previous fruit transcriptome data were compared with additional RNA-Seq data in three tissues: immature fruit, and young and mature leaves. Four categories of orchard trees were studied: symptomatic, asymptomatic, apparently healthy, and healthy. Principal component analysis found distinct expression patterns between immature and mature fruits and leaf samples for all four categories of trees. A predicted protein - protein interaction network identified HLB-regulated genes for sugar transporters playing key roles in the overall plant responses. Gene set and pathway enrichment analyses highlight the role of sucrose and starch metabolism in disease symptom development in all tissues. HLB-regulated genes (glucose-phosphate-transporter, invertase, starch-related genes) would likely determine the source-sink relationship disruption. In infected leaves, transcriptomic changes were observed for light reactions genes (downregulation), sucrose metabolism (upregulation), and starch biosynthesis (upregulation). In parallel, symptomatic fruits over-expressed genes involved in photosynthesis, sucrose and raffinose metabolism, and downregulated starch biosynthesis. We visualized gene networks between tissues inducing a source-sink shift. CaLas alters the hormone crosstalk, resulting in weak and ineffective tissue-specific plant immune responses necessary for bacterial clearance. Accordingly, expression of WRKYs (including WRKY70) was higher in fruits than in leaves. Systemic acquired responses were inadequately activated in young leaves, generally considered the sites where most new infections occur

Management of Gastroesophageal Reflux Disease (GERD) by Primary Care Providers in Mississippi

Gastroesophageal reflux disease (GERD) is one of the most common diseases seen in primary care practice. To reduce the negative effects, such as esophageal narrowing, erosions, and precancerous lesions, from uncontrolled or inadequately managed GERD, primary care providers must stay up to date on evidence-based research and integrate the most current guidelines, The American College of Gastroenterology (ACG) updated guidelines for proper management of GERD in 2021, into practice. The guidelines recommend lifestyle modifications, proper pharmacological treatment with proton pump inhibitors (PPIs) for an eight-week course, and proper follow-up and/or referral if unimproved. The purpose of this research study was to conduct chart reviews of documentation to identify if primary care providers followed current ACG guidelines. After contacting the Mississippi University for Women’s Institutional Review Board and receiving permission to conduct chart reviews at four primary care clinics in Southeastern Mississippi, the current researchers collected data from 465 patients’ charts to assess if current guidelines were being followed by Mississippi primary care providers. The quantitative retrospective study revealed the majority of primary care providers managed GERD adequately, according to current ACG guidelines. Although the data collection initially included all primary care providers, such as nurse practitioners, medical doctors, doctors of osteopathic medicine, and physicians’ assistants, only nurse practitioners and medical doctors were included in the study due to the specific clinics utilized for data collection. Overall, the study revealed nurse practitioners as more compliant than medical doctors with adhering to current ACG guidelines for management of GERD. If Mississippi primary care providers manage GERD according to the ACG guidelines, better patient outcomes can be achieved. By recommending lifestyle modifications, such as weight loss, elevation of the head of bed, refraining from eating two to three hours prior to bedtime, and avoiding trigger foods, reduction of the negative effects of GERD can be piloted. Correct pharmacological treatment with an eight-week course of PPIs can also reduce the negative outcomes produced by GERD without overtreatment that can lead to other issues, like osteoporosis. If failure of combined therapies occur, referral to a specialist should be made for further treatment. The findings also reiterate the importance of timely follow-up. By following the guidelines, primary care providers can improve patient outcomes through reducing the physical strains of GERD and the economical strains of improper management and treatment of the prevalent disease

The effect of lighting conditions and use of headlights on drivers’ perception and appraisal of approaching vehicles at junctions

Use of Daytime Running Lights (DRL) is mandatory in many countries for motorcycles, and in some for cars. However, in developing countries DRLs may be optional or compliance low. The effect of car or motorcycle headlights and lighting conditions on Malaysian drivers’ ability to perceive and judge the safety of pulling out was investigated. Stimuli were photographs depicting either daytime or nighttime taken at a T-junction with approaching vehicles with headlights on or off. Headlights improved drivers’ ability to perceive cars and motorcycles in the nighttime photographs but not the daytime photographs, although this could be due to the bright weather in the photographs. Drivers judged it less safe to pull out when approaching motorcycles had headlights on than off, regardless of the lighting conditions, supporting the utility of DRL for motorcycles. Headlights did not affect judgments for cars, questionning the utility of DRL for cars

NEEMO 20: Science Training, Operations, and Tool Development

The 20th mission of the National Aeronautics and Space Administration (NASA) Extreme Environment Mission Operations (NEEMO) was a highly integrated evaluation of operational protocols and tools designed to enable future exploration beyond low-Earth orbit. NEEMO 20 was conducted from the Aquarius habitat off the coast of Key Largo, FL in July 2015. The habitat and its surroundings provide a convincing analog for space exploration. A crew of six (comprised of astronauts, engineers, and habitat technicians) lived and worked in and around the unique underwater laboratory over a mission duration of 14-days. Incorporated into NEEMO 20 was a diverse Science Team (ST) comprised of geoscientists from the Astromaterials Research and Exploration Science (ARES/XI) Division from the Johnson Space Center (JSC), as well as marine scientists from the Department of Biological Sciences at Florida International University (FIU). This team trained the crew on the science to be conducted, defined sampling techniques and operational procedures, and planned and coordinated the science focused Extra Vehicular Activities (EVAs). The primary science objectives of NEEMO 20 was to study planetary sampling techniques and tools in partial gravity environments under realistic mission communication time delays and operational pressures. To facilitate these objectives two types of science sites were employed 1) geoscience sites with available rocks and regolith for testing sampling procedures and tools and, 2) marine science sites dedicated to specific research focused on assessing the photosynthetic capability of corals and their genetic connectivity between deep and shallow reefs. These marine sites and associated research objectives included deployment of handheld instrumentation, context descriptions, imaging, and sampling; thus acted as a suitable proxy for planetary surface exploration activities. This abstract briefly summarizes the scientific training, scientific operations, and tool development conducted during NEEMO 20 with an emphasis on the primary lessons learned