Bullying Experiences of Individuals with Visual Impairment: The Mitigating Role of Sport Participation

In bullying research, status plays a key role in who is the instigator and who is the recipient of bullying. Athletes are often considered a high status individual and have been accused of engaging in bullying behaviors. Individuals with disabilities are seen as possessing lower status and are often the victims of bullying. What is unclear is if athletes who have a disability are instigators of bullying or are victims themselves. This study explored implications of status as it relates to bullying experiences by athletes and non-athletes with visual impairments. Specific attention was paid to uncovering similarities and differences between the two groups. Results indicate that individuals with visual impairments are both the victim and instigator of bullying activities. The hypothesis of status as a factor in bullying was supported within both populations

National Leadership Index 2008: A National Study of Confidence in Leadership

The National Study of Confidence in Leadership is a social science research program examining the attitudes of the American public toward the nation’s leadership. The study includes the National Leadership Index 2008, a multidimensional measure of the public’s confidence in leadership within different sectors of society. The study was pioneered in 2005 by the Center’s Research Director, Professor Todd L. Pittinsky.Center for Public Leadershi

Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial

Purpose Benefit from convalescent plasma therapy for coronavirus disease 2019 (COVID-19) has been inconsistent in randomized clinical trials (RCTs) involving critically ill patients. As COVID-19 patients are immunologically heterogeneous, we hypothesized that immunologically similar COVID-19 subphenotypes may differ in their treatment responses to convalescent plasma and explain inconsistent findings between RCTs . Methods We tested this hypothesis in a substudy involving 1239 patients, by measuring 26 biomarkers (cytokines, chemokines, endothelial biomarkers) within the randomized, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia (REMAP-CAP) that assigned 2097 critically ill COVID-19 patients to either high-titer convalescent plasma or usual care. Primary outcome was organ support free days at 21 days (OSFD-21) . Results Unsupervised analyses identified three subphenotypes/endotypes. In contrast to the more homogeneous subphenotype-2 (N = 128 patients, 10.3%; with elevated type i and type ii effector immune responses) and subphenotype-3 (N = 241, 19.5%; with exaggerated inflammation), the subphenotype-1 had variable biomarker patterns (N = 870 patients, 70.2%). Subphenotypes-2, and -3 had worse outcomes, and subphenotype-1 had better outcomes with convalescent plasma therapy compared with usual care (median (IQR). OSFD-21 in convalescent plasma vs usual care was 0 (− 1, 21) vs 10 (− 1, to 21) in subphenotype-2; 1.5 (− 1, 21) vs 12 (− 1, to 21) in suphenotype-3, and 0 (− 1, 21) vs 0 (− 1, to 21) in subphenotype-1 (test for between-subphenotype differences in treatment effects p = 0.008). Conclusions We reported three COVID-19 subphenotypes, among critically ill adults, with differential treatment effects to ABO-compatible convalescent plasma therapy. Differences in subphenotype prevalence between RCT populations probably explain inconsistent results with COVID-19 immunotherapies

The Quality of Response Time Data Inference: A Blinded, Collaborative Assessment of the Validity of Cognitive Models

Most data analyses rely on models. To complement statistical models, psychologists have developed cognitive models, which translate observed variables into psychologically interesting constructs. Response time models, in particular, assume that response time and accuracy are the observed expression of latent variables including 1) ease of processing, 2) response caution, 3) response bias, and 4) non-decision time. Inferences about these psychological factors, hinge upon the validity of the models’ parameters. Here, we use a blinded, collaborative approach to assess the validity of such model-based inferences. Seventeen teams of researchers analyzed the same 14 data sets. In each of these two-condition data sets, we manipulated properties of participants’ behavior in a two-alternative forced choice task. The contributing teams were blind to the manipulations, and had to infer what aspect of behavior was changed using their method of choice. The contributors chose to employ a variety of models, estimation methods, and inference procedures. Our results show that, although conclusions were similar across different methods, these "modeler’s degrees of freedom" did affect their inferences. Interestingly, many of the simpler approaches yielded as robust and accurate inferences as the more complex methods. We recommend that, in general, cognitive models become a typical analysis tool for response time data. In particular, we argue that the simpler models and procedures are sufficient for standard experimental designs. We finish by outlining situations in which more complicated models and methods may be necessary, and discuss potential pitfalls when interpreting the output from response time models

Cellular Packing, Mechanical Stress and the Evolution of Multicellularity

Presented at the Symposium on Soft Matter Forefronts "Contributed Talks", April 19, 2018, from 10:20 a.m.-11:10 a.m. at the Marcus Nanotechnology Building, Rooms 1116-1118, Georgia Tech.Chairs: Michael Tennenbaum & Alberto Fernandez-Nieves (Georgia Tech).Shane Jacobeen is with the Georgia Institute of Technology.Runtime: 09:46 minutesThe evolution of multicellularity set the stage for sustained increases in organismal complexity. However, a fundamental aspect of this transition remains largely unknown: how do simple clusters of cells evolve increased size when confronted by forces capable of breaking intracellular bonds? Here we show that multicellular snowflake yeast clusters fracture due to crowding-induced mechanical stress. Over seven weeks (~291 generations) of daily selection for large size, snowflake clusters evolve to increase their radius 1.7-fold by reducing the accumulation of internal stress. During this period, cells within the clusters evolve to be more elongated, concomitant with a decrease in the cellular volume fraction of the clusters. The associated increase in free space reduces the internal stress caused by cellular growth, thus delaying fracture and increasing cluster size. This work demonstrates how readily natural selection finds simple, physical solutions to spatial constraints that limit the evolution of group size—a fundamental step in the evolution of multicellularity.Georgia Institute of Technology. College of SciencesGeorgia Institute of Technology. Institute for MaterialsGeorgia Institute of Technology. Parker H. Petit Institute for Bioengineering and BioscienceGeorgia Institute of Technology. School of Materials Science and EngineeringGeorgia Institute of Technology. School of PhysicsAmerican Physical SocietyExxon Mobil CorporationNational Science Foundation (U.S.

National Leadership Index 2008

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Research in Diversity―Highlighting findings on individuals with visual impairments (Panel)

Our presentation will highlight the current research regarding physical and psychological health among children and adolescents with visual impairments. Specifically, our panel of students and faculty from across disciplines will discuss the impact of several recent studies on this population, as well as the importance of including diverse populations in the research process. In addition, our panelists will discuss the urgent need for continued research pertaining to physical and psychological health among this particular population. Faculty and students are from the Departments of Psychology and Kinesiology, Sport Studies, and Physical Education. We will discuss topics such as barriers to physical activity, the impact of physical activity and sedentary behavior on health, motor development and balance, and the impact of bullying on psychological outcomes. GOAL/OUTCOME #1 Highlight findings in current research among children/adolescents with visual impairments. GOAL/OUTCOME #2 Discuss the impact of this research on overall health among this population. GOAL/OUTCOME #3 Demonstrate the need for further research within diverse populations