409 research outputs found

    El uso de los espacios virtuales de aprendizaje de los docentes del Centro Universitario de Paysandú

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    Tesis de Maestría en Procesos Educativos Mediados por tecnologías Directora: Dra. Berlarmina BenítezMaestría en Procesos Educativos Mediados por tecnologíasCentro de Estudios Avanzados, Facultad de Ciencias Sociales, Universidad Nacional de CórdobaFecha de defensa: 11 de agosto de 201

    The Patient's Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy.

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    BackgroundThe Goeckerman regimen remains one of the oldest, most reliable treatment options for patients with moderate to severe psoriasis. Goeckerman therapy currently consists of exposure to ultraviolet B light and application of crude coal tar. The details of the procedure can be confusing and challenging to understand for the first-time patient or provider.ObjectiveTo present a freely available online guide and video on Goeckerman treatment that explains the regimen in a patient-oriented manner.MethodsThe Goeckerman protocol used at the University of California-San Francisco Psoriasis and Skin Treatment Center as well as available information from the literature were reviewed to design a comprehensive guide for patients receiving Goeckerman treatment.ResultsWe created a printable guide and video resource that covers the supplies needed for Goeckerman regimen, the treatment procedure, expected results, how to monitor for adverse events, and discharge planning.ConclusionThis new resource is beneficial for prospective patients planning to undergo Goeckerman treatment, healthcare providers, and trainees who want to learn more about this procedure. Online media and video delivers material in a way that is flexible and often familiar to patients

    The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy.

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    BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of PUVA. Studies have shown that patients who viewed videos explaining the treatment procedures for various medical conditions had a greater understanding of their treatment and were more active participants in their health.ObjectiveTo present a freely available online guide and video on PUVA treatment designed for patient education on PUVA.MethodsThe PUVA treatment protocol used at the University of California-San Francisco Psoriasis and Skin Treatment Center as well as available information from the literature was reviewed to design a comprehensive guide for patients receiving PUVA treatment.ResultsWe created a printable guide and video resource that reviews the benefits and risks of PUVA, discusses the three types of PUVA (hand-foot soak, full body soak, and systemic), demonstrates the PUVA process, and provides practical tips for safe use.ConclusionOnline media and video delivers material in a way that is flexible and often familiar to patients. This new format is beneficial for prospective patients planning to undergo PUVA treatment, health-care providers, and trainees who want to learn more about this treatment

    Primer Censo Docente del Centro Universitario de Paysandú : características demográficas y utilización de TIC

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    Presentación, Contexto institucional. -- Metodología. Identificación de la población objetivo . -- Resultados y análisis . Caracterización docente. Rasgos sociodemográficos. Uso de tic. -- Opinión sobre el uso de las tic en la educación. -- Conclusiones. -- Bibliografía. -- Anexo i. Formulario del Primer Censo Docente del cup. -- Anexo ii. Tablas y gráficas del Primer Censo Docente del cup

    Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability

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    Background:The efficacy and safety of biologic and phototherapy in treating moderate-to-severe psoriasis is well known. However, some patients may not respond well to biologic agents or phototherapy on their own and may require combination therapy. Skillfully combining a biologic agent and phototherapy may provide an additive improvement without much increase in risks. Objective:To summarize the current state of evidence for the efficacy and safety of combining biologics with phototherapy in the treatment of moderate-to-severe plaque psoriasis. Methods:We conducted an extensive search on Pubmed database for English language literature that evaluated the use of a combination of biologic and phototherapy for the treatment of moderate-to-severe psoriasis through January 2016. The search included the following key-words: psoriasis, etanercept, adalimumab, infliximab, ustekinumab, biologics, phototherapy, and combination therapy. Results:The primary literature included randomized controlled trials, a head-to-head study, open-label controlled and uncontrolled trials, case series, and case reports. Etanercept was used in over half of the reported cases, but other biologic agents used included ustekinumab, adalimumab, and infliximab. The vast majority of phototherapy was narrowband ultraviolet B (NBUVB) radiation. Most cases reported enhanced improvement with combination therapy. Serious adverse events throughout the study duration were reported in <3% of the patients. Long-term adverse events cannot be excluded. Conclusion:Combination of biologic and phototherapy appears to be a viable clinical strategy in the treatment of moderate-to-severe psoriasis not responsive to monotherapy, despite limitations in the data available. NBUVB in combination with biologics appears to be especially effective. However, the long-term impact of these combinations is yet to be determined

    Pósteres como estrategia de Alfabetización Académica

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    Con el fin de propiciar la inmersión temprana de los estudiantes en la cultura científica y contribuir al mejoramiento de sus competencias para la comunicación del conocimiento disciplinar, se estimuló su participación activa en situaciones discursivas propias del ámbito académico. Para eso fueron creados espacios de trabajo conjunto entre docentes y estudiantes, en los que se elaboraron pósteres sobre experiencias realizadas en la universidad, para su presentación en eventos académicos. Fueron realizados dos ciclos de investigación-acción en 2013 y 2015 en el Centro Universitario de Paysandú. El primer ciclo consistió en el acompañamiento docente a estudiantes de diversas carreras mediante talleres presenciales y seguimiento virtual, trabajándose en la revisión y reescritura de los resúmenes presentados, así como en el diseño y textos a incorporar a los pósteres. Este ciclo permitió identificar la necesidad de involucrar a un docente de la disciplina que oriente a cada grupo. Asimismo, posibilitó detectar el interés de egresados recientes y docentes nóveles en participar. Estos aspectos se tomaron en cuenta en la segunda edición, en la que también se incorporaron nuevos recursos y herramientas. Las experiencias realizadas promovieron el aprendizaje activo, el trabajo colaborativo y la interacción entre diferentes actores. Una evaluación participativa permitió constatar el carácter formativo del proceso, en el doble sentido de habilitar la profundización en los contenidos disciplinares y acercar a los estudiantes a la especificidad del discurso disciplinar

    Mechanisms and advancement of antifading agents for fluorescence microscopy and single-molecule spectroscopy

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    Modern fluorescence microscopy applications go along with increasing demands for the employed fluorescent dyes. In this work, we compared antifading formulae utilizing a recently developed reducing and oxidizing system (ROXS) with commercial antifading agents. To systematically test fluorophore performance in fluorescence imaging of biological samples, we carried out photobleaching experiments using fixed cells labeled with various commonly used organic dyes, such as Alexa 488, Alexa 594, Alexa 647, Cy3B, ATTO 550, and ATTO 647N. Quantitative evaluation of (i) photostability, (ii) brightness, and (iii) storage stability of fluorophores in samples mounted in different antifades (AFs) reveal optimal combinations of dyes and AFs. Based on these results we provide guidance on which AF should preferably be used with a specific dye. Finally, we studied the antifading mechanisms of the commercial AFs using single-molecule spectroscopy and reveal that these empirically selected AFs exhibit similar properties to ROXS AFs
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