Ultra-wide band energy harvesting for ultra-low power electronics applications

In this work, the feasibility of energy harvesting in the useful UWB band (i.e., 3.1-10.6 GHz) is analytically investigated. A typical UWB communications/EH chain in this band is modeled and analyzed, considering the spectral constraints imposed by the federal communications commission (FCC) to UWB signaling. Based on the developed model, accurate analytical expressions are derived for the average received powers of two common types of impulse radio UWB (IR-UWB) signaling waveforms. Numerical simulations on the system-level show excellent agreement with the obtained analytical expressions. Moreover, the DC power levels expected from spectrally constrained IR-UWB waveforms are extremely low (less than 0.3 microwatt) and, accordingly, provide useful guidelines for the design and development of ULP electronics applications in the sub-microwatt range

Investigation of surface integrity in laser-assisted machining of nickel based superalloy

While laser-assisted machining can significantly improve the machinability of nickel-based superalloy, the mechanism of surface integrity evolution and its influence on the material functional performance is still not clear. The present study gives a comprehensive investigation on the surface integrity of laser-assisted milling (LAMill) process with an in-depth study of the mechanism of chip formation, microstructural and mechanical alternations, supported by key outcomes from the two constitutive processes, conventional milling (CMill) and single laser scanning (LS). Although the high thermal affected layer in LAMill process has been removed through the cutting chips, a significant bending effect has been found in both the LAMill and LS workpiece. More interestingly, a combined impact of the residual stress from LS and CMill has been found on LAMill workpiece while a lattice evolution has been revealed regarding both the thermal and mechanical influence. Specifically, inadequate fatigue performance on LAMill and LS workpiece has been found due to the high thermal effect in the superficial layer regarding the residual tensile stress distribution and microstructure variation. While LAMill is generally considered as a promising machining method with improved machinability of difficult-to-cut materials, this research shows a poor workpiece functional performance (fatigue) and justifies its application prospect

Fabrication of Tm2O3/Al2O3-silica preform by improved MCVD-chelate delivery system

The fabrication of Tm/Al-doped silica preforms by an improved MCVD method with metal chelate precursors is discussed. Two fabrication techniques are employed, namely; simultaneous soot-dopant deposition (or standard MCVD) and stepwise soot-dopant deposition. The preforms are characterized by refractive index profiler and EPMA. The results show that the stepwise soot-dopant technique has a higher incorporation of Al2O3 and Tm2O3 as compared to the simultaneous soot-dopant method. This is due to the drawbacks of our chelate delivery system such as the temperature gradient and flow design. For the stepwise technique, the measured index difference of the preform is 0.006 with 0.8 wt% (maximum) Tm incorporated in the core

TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors

<p>Abstract</p> <p>Background</p> <p>Members of the TRIP-Br/SERTAD family of mammalian transcriptional coregulators have recently been implicated in E2F-mediated cell cycle progression and tumorigenesis. We, herein, focus on the detailed functional characterization of the least understood member of the TRIP-Br/SERTAD protein family, TRIP-Br2 (SERTAD2).</p> <p>Methods</p> <p>Oncogenic potential of TRIP-Br2 was demonstrated by (1) inoculation of NIH3T3 fibroblasts, which were engineered to stably overexpress ectopic TRIP-Br2, into athymic nude mice for tumor induction and (2) comprehensive immunohistochemical high-throughput screening of TRIP-Br2 protein expression in multiple human tumor cell lines and human tumor tissue microarrays (TMAs). Clinicopathologic analysis was conducted to assess the potential of TRIP-Br2 as a novel prognostic marker of human cancer. RNA interference of <it>TRIP-Br2 </it>expression in HCT-116 colorectal carcinoma cells was performed to determine the potential of TRIP-Br2 as a novel chemotherapeutic drug target.</p> <p>Results</p> <p>Overexpression of TRIP-Br2 is sufficient to transform murine fibroblasts and promotes tumorigenesis in nude mice. The transformed phenotype is characterized by deregulation of the E2F/DP-transcriptional pathway through upregulation of the key E2F-responsive genes <it>CYCLIN E</it>, <it>CYCLIN A2</it>, <it>CDC6 </it>and <it>DHFR</it>. TRIP-Br2 is frequently overexpressed in both cancer cell lines and multiple human tumors. Clinicopathologic correlation indicates that overexpression of TRIP-Br2 in hepatocellular carcinoma is associated with a worse clinical outcome by Kaplan-Meier survival analysis. Small interfering RNA-mediated (siRNA) knockdown of TRIP-Br2 was sufficient to inhibit cell-autonomous growth of HCT-116 cells <it>in vitro</it>.</p> <p>Conclusion</p> <p>This study identifies <it>TRIP-Br2 </it>as a <it>bona-fide </it>protooncogene and supports the potential for TRIP-Br2 as a novel prognostic marker and a chemotherapeutic drug target in human cancer.</p

Design and performance evaluation of a novel metamaterial broadband THz filter for 6G applications

Terahertz (THz) radiation, which has applications in the imaging of objects, non-destructive testing, satellite communication, medical diagnostics, and biosensing, has generated a great deal of attention due to its remarkable properties. This paper proposes a novel broadband filter for THz applications. The main idea is to overcome the insertion loss and bandwidth issues by modeling a frequency-domain finite difference method and guided-mode resonance (GMR). The optimal design scheme of the wideband pass filter based on the circular resonant ring is discussed by comparing the transmission parameters under various parameters. This scheme overcomes the restriction of the narrow passband bandwidth of the prior THz filters and achieves approximately 3 dB bandwidth of 0.54 THz. The proposed THz filter paper also has the advantages of a straightforward structure, low processing costs, and ease of conformal with other structures, and it can be used for stealth fighters, new communication technology, and precise instruments. In addition, when compared to existing models, the suggested filter offers higher 3 dB BW operation, increased transmittance, low insertion loss, and stable performance at various oblique angles

Design technique to mitigate unwanted coupling in densely packed radiating elements of an antenna array for electronic devices and wireless communication systems operating in the millimeter-wave band

An innovative design is presented of a metamaterial inspired antenna array for millimeter-wave band applications where non-mechanical beam-steering is required such as in 5G and 6G communications, automotive and radar systems. In communication systems beam-steering antennas can significantly improve signal-to-noise ratio, spatial directivity, and the efficiency of data transmission. However, in tightly packed arrays the effects of mutual coupling between the radiating elements can severely limit the array’s performance. The proposed antenna array consists of a 3×3 matrix of patch radiators that are tightly packed and interconnected to each other. Rows of radiators are demarcated by a horizontal microstrip transmission-line whose ends are short-circuited to the ground-plane. This technique reduces unwanted surface waves that contribute to undesired coupling. Embedded in the square patch radiators is a rhombus shaped slot that increases the effective aperture of the antenna with no impact on the antenna’s size. As the antenna is excited via a single feedline the edge-to-edge spacing between the radiators and the interconnected feedlines are made such that there is phase coherency at the radiating elements. Measured results show that the effectiveness of the proposed array in simultaneously improving its impedance bandwidth and radiation characteristics. The measured peak gain and radiation efficiency are 13.6 dBi and 89.54%, respectively

Metasurface-Inspired Flexible Wearable MIMO Antenna Array for Wireless Body Area Network Applications and Biomedical Telemetry Devices

This article presents a sub-6GHz ISM-band flexible wearable MIMO antenna array for wireless body area networks (WBANs) and biomedical telemetry devices. The array is based on metasurface inspired technology. The antenna array consists of 2×2 matrix of triangular-shaped radiation elements that were realized on 0.8 mm thick Rogers RT/duroid 5880 substrate. Radiation characteristics of the array are enhanced by isolating the surface current interaction between the individual radiators in the array. This is achieved by inserting an electromagnetic bandgap (EBG) decoupling structure between the radiating elements. The radiating elements were transformed into a metasurface by etching sub-wavelength slots inside them. The periodic arrangement of slots acts like resonant scatterers that manipulate the electromagnetic response of the surface. Results confirm that by employing the decoupling structure and sub-wavelength slots the isolation between the radiators is significantly improved (>34.8 dB). Moreover, there is an improvement in the array’s fractional bandwidth, gain and the radiation efficiency. The optimized array design for operation over 5.0-6.6 GHz has an average gain and efficiency of 10 dBi and 83%, respectively. Results show that the array’s performance is not greatly affected by a certain amount of bending. In fact, the antenna maintains a gain between 8.65-10.5 dBi and the efficiency between 77-83%. The proposed MIMO antenna array is relatively compact, can be easily fabricated on one side of a dielectric material, allows easy integration with RF circuitry, is robust, and maintains its characteristics with some bending. These features make it suitable for various wearable applications and biomedical telemetry devices

Metasurface-inspired flexible wearable MIMO antenna array for wireless body area network applications and biomedical telemetry devices

This article presents a sub-6GHz ISM-band flexible wearable MIMO antenna array for wireless body area networks (WBANs) and biomedical telemetry devices. The array is based on metasurface inspired technology. The antenna array consists of 2 x 2 matrix of triangular-shaped radiation elements that were realized on 0.8 mm thick Rogers RT/duroid 5880 substrate. Radiation characteristics of the array are enhanced by isolating the surface current interaction between the individual radiators in the array. This is achieved by inserting an electromagnetic bandgap (EBG) decoupling structure between the radiating elements. The radiating elements were transformed into a metasurface by etching sub-wavelength slots inside them. The periodic arrangement of slots acts like resonant scatterers that manipulate the electromagnetic response of the surface. Results confirm that by employing the decoupling structure and sub-wavelength slots the isolation between the radiators is significantly improved (>34.8 dB). Moreover, there is an improvement in the array's fractional bandwidth, gain and the radiation efficiency. The optimized array design for operation over 5.0-6.6 GHz has an average gain and efficiency of 10 dBi and 83%, respectively. Results show that the array's performance is not greatly affected by a certain amount of bending. In fact, the antenna maintains a gain between 8.65-10.5 dBi and the efficiency between 77-83%. The proposed MIMO antenna array is relatively compact, can be easily fabricated on one side of a dielectric material, allows easy integration with RF circuitry, is robust, and maintains its characteristics with some bending. These features make it suitable for various wearable applications and biomedical telemetry devices

Tracking the spatial footprints of extreme storm surges around the coastline of the UK and Ireland

Storm surges are the most important driver of flooding in many coastal areas. Understanding the spatial extent of storm surge events has important financial and practical implications for flood risk management, reinsurance, infrastructure reliability and emergency response. In this paper, we apply a new tracking algorithm to a high-resolution surge hindcast (CODEC, 1980–2017) to characterize the spatial dependence and temporal evolution of extreme surge events along the coastline of the UK and Ireland. We quantify the severity of each spatial event based on its footprint extremity to select and rank the collection of events. Several surge footprint types are obtained based on the most impacted coastal stretch from each particular event, and these are linked to the driving storm tracks. Using the collection of the extreme surge events, we assess the spatial distribution and interannual variability of the duration, size, severity, and type. We find that the northeast coastline is most impacted by the longest and largest storm surge events, while the English Channel experiences the shortest and smallest storm surge events. The interannual variability indicates that the winter seasons of 1989-90 and 2013–14 were the most serious in terms of the number of events and their severity, based on the return period along the affected coastlines. The most extreme surge event and the highest number of events occurred in the winter season 1989–90, while the proportion of events with larger severities was higher during the winter season 2013–14. This new spatial analysis approach of surge extremes allows us to distinguish several categories of spatial footprints of events around the UK/Ireland coast and link these to distinct storm tracks. The spatial dependence structures detected can improve multivariate statistical methods which are crucial inputs to coastal flooding assessments