Sintomas respiratórios na população da cidade de Ribeirão Preto, SP (Brasil): resultados da aplicação de um questionário padronizado

As doenças respiratórias constituem expressiva parcela da morbidade na população da cidade de Ribeirão Preto, como comprovam alguns autores. Em particular, as doenças pulmonares crônicas não-específicas motivam número grande de internações a cada ano. Tais doenças podem ser detectadas através de sintomas relatados em entrevistas pessoais, quando se usa um questionário padronizado. Em uma amostra de 3.353 indivíduos de mais de 3 anos de idade, correspondendo a 878 domicílios visitados, foi feito levantamento de sintomas respiratórios, na população do município de Ribeirão Preto, SP (Brasil), utilizando-se questionário padronizado. Os resultados mostraram: 3,4% de pessoas do sexo feminino e 2,4% do sexo masculino com sintomas sugestivos da asma brônquica; 5,5% do sexo masculino e 3,3% do sexo feminino com sintomas sugestivos de bronquite crônica; 15,5% dos homens e 11,3% das mulheres referiram tosse; dispnéia com limitação funcional foi relatada em 0,96% dos homens e 2,48% das mulheres.The prevalence of asthma, chronic bronchitis and some other respiratory symptoms was estimated on the basis of a standardized questionnaire. Three thousand three hundred and fifty-three people were interviewed at home. On the basis of the criteria adapted 3.49% of the females and 2.4% of the males were considered asthmatic. Likewise, in 5.54% of the males and 3.37% of females the symptoms were strongly suggestive of chronic bronchitis. Shortness of breath was recorded in 0.96% of the males and 2.48% of the females

COVID-19 and pulmonary embolism: do not forget the association!

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Incidence of tuberculous and non-tuberculous mycobacteria, differentiated by multiplex PCR, in clinical specimens of a large general hospital

OBJECTIVE: To determine the incidence of Mycobacterium tuberculosis complex and non-tuberculous mycobacterial isolates in the routine setting of a large general hospital using an "in-house" multiplex polymerase chain reaction method and to establish a paradigm for the definitive identification of mycobacteria isolated using semi-automated equipment. METHODS: Established tests, including polymerase chain reaction restriction enzyme analysis, PNB, and NAP inhibition tests as the gold standard, showed 100% agreement with an IS6110/hsp65 multiplex polymerase chain reaction when used to identify stock strains (n = 117). RESULTS: In a subsequent study, 8,790 clinical specimens producing 476 isolates were evaluated with multiplex PCR and also showed 100% agreement in identification using PRA-polymerase chain reaction as the gold standard. The application of this technique to routine analysis was demonstrated in this study. A method was established with the initial application of multiplex PCR for all positive liquid cultures and the subsequent identification of non-tuberculous mycobacteria by polymerase chain reaction restriction enzyme analysis. In total, 77% of isolates belonged to the Mycobacterium tuberculosis complex, and 23% were non-tuberculous mycobacteria. CONCLUSIONS: Several non-tuberculous mycobacterial species were identified, primarily M. avium, but other potentially pathogenic species were also frequently observed, including M. fortuitum, M. abscessus, and M. kansasii. The expeditious communication of these data to the clinical staff was fundamental for the diagnosis of clinical cases. Even in settings where tuberculosis is of major importance, the incidence of non-tuberculous mycobacteria infection is substantial

Evaluation of the patellar height in athletes with diagnosed with chronic tendinopathy of the knee extensor mechanism

OBJECTIVES: To carry out a radiographic evaluation of patellar height in athletes diagnosed with chronic tendinopathy of the knee extensor mechanism; METHODS: Radiographic assessments were carried out on 65 patients (110 knees) aged between 15 and 40 years, who practiced different kinds of sports, some with of chronic tendinopathy of the knee extensor mechanism (jumper's knee) and others without. The athletes were divided into two groups: those with diagnosed jumper's knee (group 1:38 athletes - 56 knees) and a control group (group 2:27 athletes - 54 knees). In group 1, 18 of the athletes presented the condition in both knees on examination. The height of the patella was measured using the Insall-Salvati and Blackburne-Peel x-ray methods. CONCLUSION: The presence of a high patella in the group of athletes with chronic tendinopathy of the knee extensor mechanism was significantly higher than in the control group.OBJETIVO: Avaliar radiograficamente a altura patelar de atletas com diagnóstico de tendinopatia crônica do aparelho extensor do joelho (TCAE). MÉTODOS: Na amostra foram avaliados radiograficamente 65 pacientes (110 joelhos) com idade entre 15 e 40 anos e de diferentes modalidades esportivas com e sem diagnóstico de tendinopatia crônica do aparelho extensor do joelho (jumper's knee). Os atletas foram divididos em dois grupos: aqueles com diagnóstico de TCAE (grupo 1: 38 atletas - 56 joelhos) e um grupo que denominamos de controle (grupo 2: 27 atletas - 54 joelhos). RESULTADOS: No grupo 1 tivemos 18 atletas que apresentavam a doença bilateralmente na ocasião dos exames. Para a medida da altura patelar utilizamos os índices radiográficos de Insall e Salvati e Blackburne e Peel. CONCLUSÃO: A presença de patela alta no grupo de atletas com tendinopatia crônica do aparelho extensor do joelho foi significante maior do que a observada no grupo controle.Universidade Federal de São Paulo (UNIFESP)UNIFESPSciEL

Prevalence of Pain on Palpation of the Inferior Pole of the Patella Among Patients with Complaints of knee Pain

CONTEXT AND OBJECTIVE: Patellar tendinopathy is a common condition in sports. It may occur at any location of the patellar tendon, but the most commonly affected area is the inferior pole of the patella. Among various diagnostic tests, the one most used is palpation of the inferior pole of the patella. The aim of this study was to investigate the prevalence of pain complaints among individuals with pathological knee conditions and to evaluate palpation of the inferior pole of the patella as a diagnostic test for patellar tendinopathy. METHODS: Palpation of the patellar tendon was performed on 318 individuals who presented with knee-related complaints. Palpation was performed with the individual in the supine position and the knee extended. The age, gender, physical activity and labor activity of each individual were recorded at the time the symptoms appeared; the diagnosis was also recorded. RESULTS: Of the total number of individuals evaluated, 124 (39%) felt pain on palpation of the inferior pole of the patella. Of these, only 40 (32.3%) received a diagnosis of patellar tendinopathy. We did not observe any difference with respect to gender and age distribution. When evaluating daily physical activity levels, however, we observed that individuals with pain on palpation of the inferior pole of the patella experienced more intense physical activity. CONCLUSIONS: Palpation of the inferior pole of the patella is a diagnostic procedure with high sensitivity and moderate specificity for diagnosing patellar tendinopathy, especially among individuals who perform activities with high functional demands

Glycogen Kinetics of Wistar Rats: Different Exercise Intensities and Tissue Analyzed Influence

International Journal of Exercise Science 15(2): 289-299, 2022. The aim of this study is to verify the influence of the intensity on muscle and hepatic glycogen depletion and recovery kinetics of Wistar rats, submitted to three acute training sessions with equalized loads. 81 male Wistar rats performed an incremental test to determine maximal running speed (MRS) and divided into 4 groups: baseline group (Control; n = 9); low intensity training session (GZ1; n = 24; 48 minutes at 50% of MRS); moderate intensity group (GZ2; n = 24; 32 minutes at 75% of MRS) and high intensity group (GZ3; n = 24; 5x5 minutes and 20 seconds at 90% of MRS). Immediately after the sessions and after 6, 12 and 24 hours, 6 animals from each subgroup were euthanized for glycogen quantification in soleus and EDL muscles and liver. A Two-Way ANOVA and the Fisher\u27s Post-hoc test was used (p \u3c 0.05). Glycogen supercompensation occurred between 6 and 12 hours after exercise in muscle tissue and 24 after exercise in the liver. The muscle and hepatic glycogen depletion and recovery kinetics are not modulated by exercise intensity since the load was equalized, but effects were distinct in different tissues. Hepatic glycogenolysis and muscle glycogen synthesis processes seem to run in parallel

New insight on the solidification path of an alloy 625 weld overlay

AbstractNi-based alloys are a special class of engineering material with excellent corrosion resistance in harsh environments. However, microstructural changes due to the solidification, may result in solidification cracks and reduction in the corrosion resistance. Knowing the microchemical and microstructural evolutions during the solidification of these alloys is essential for the understanding of the relationship between the metallurgical aspects and the properties. This research presents a new insight on the solidification path of alloy 625 weld metals deposited by the TIG cold wire process on the C–Mn steel plates. After the welding, samples having been extracted and evaluated by the scanning electron microscope, transmission electron microscopy and energy dispersive X-ray spectroscopy techniques. The results showed the presence of two types of secondary phases, identified as Laves phase and complex nitride/carbide particles. Due to the presence of nitrides particles, stable in the solid state during the melting of the alloy, during the solidification it is noted the occurrence of a complex nitride/carbide precipitation. This implies in a new route to explain the solidification of the aforementioned alloy

Lipossarcoma of the knee in a tennis player: case report

Lipossarcoma is an uncommon malignant tumor. It originates in the mesenchymal cells, and is the most common of the soft tissue sarcomas. The authors report a case of a 40 year-old male tennis player with lipossarcoma in the posterior right knee and distal thigh region.O lipossarcoma é uma neoplasia rara, originária de células mesenquimais primitivas e, entre os sarcomas, é o tipo histológico mais frequente. Os autores relatam o caso de um lipossarcoma localizado em região de joelho e coxa posterior distal direita de um paciente de 40 anos, jogador de tênis.Universidade Federal de São Paulo (UNIFESP) Departamento de Ortopedia e TraumatologiaUNIFESP, Depto. de Ortopedia e TraumatologiaSciEL