6 research outputs found
Targeted nanoconjugate co-delivering siRNA and tyrosine kinase inhibitor to Kras mutant NSCLC reveals Gab1 assisted survival pathway post oncogene knockdown
Near infrared navigation system (NAVI) for real time visualization of blood flow
Poster presented at the 2017 Health Sciences Research Day which was organized and sponsored by the University of Missouri School of Medicine Research Council and held on November 9, 2017.Summary: A portable and economical NAVI camera system that can be utilized for intraoperative fluorescence imaging has been fabricated. The NAVI system has been validated by conducting preclinical grafting studies in swine model. Finally, the clinical translational capability of the NAVI imaging system has been established using suitable clinical studies. Future study: The NAVI imaging system is being explored for lymph node imaging and other applications
Mechanics of mass, energy and momentum transfer in complex textured materials at micro/nanoscales.
Mechanics of mass, energy and momentum transfer in complex textured materials at micro/nanoscales
NONLINEAR DYNAMICS AND ITS APPLICATIONS IN MICRO- AND NANORESONATORS
This review provides a summary of the work completed to date on the nonlinear dynamics of resonant micro- and nanoelectromechanical systems (MEMS/NEMS). This research area, which has been active for approximately a decade, involves the study of nonlinear behaviors arising in small scale, vibratory, mechanical devices that are typically integrated with electronics for use in signal processing, actuation, and sensing applications. The inherent nature of these devices, which includes low damping, desired resonant operation, and the presence of nonlinear potential fields, sets an ideal stage for the appearance of nonlinear behavior, and this allows engineers to beneficially leverage nonlinear dynamics in the course of device design. This work provides an overview of the fundamental research on nonlinear behaviors arising in micro/nanoresonators, including direct and parametric resonances, parametric amplification, impacts, selfexcited oscillations, and collective behaviors, such as localization and synchronization, which arise in coupled resonator arrays. In addition, the work describes the active exploitation of nonlinear dynamics in the development of resonant mass sensors, inertial sensors, and electromechanical signal processing systems. The paper closes with some brief remarks about important ongoing developments in the field