Agronomic, economic and ecological aspects of the papaya (Carica papaya) production in Tabasco, Mexico

The cultivation of papaya is important in the tropic because it provides source of income to the farmer within a short time. Statistical data were obtained from farmers located in the Chontalpa, Rios and Centro-Sierra regions; the size of the survey was 67 farmers. The study shows the results of the farmers’ problem in a drastic reduction of their productivity because of the virosis and low prices in commercialization. The farmers were classified into three levels of technology, “low”, “middle” and “high”. The first one covers 88% of the farmers in seasonal conditions in contrast with the high technology that concentrates 4.5% in irrigation conditions. According to the technology used, the fertilizer shows more yields. Economically, the high technology had an internal tax return of 0.43 in comparison with the low technology of 0.25, which means that the investment is recovered with different yields. However, the use of high technology makes the system more competitive. Key words

Masculine, feminine and neutral sports: Extracurricular sport modalities in practice

The present work constitutes a novel approach to extracurricular sport modalities. The aim was to analyze the participation model and to determine the relevance of sex in this context. Data from 616 students, aged 15 to 17, were collected. The questionnaire on sport lifestyle from a gender perspective (Alvariñas-Villaverde et al., 2009) was used for assessment. The results showed that sport choice corresponds to sports traditionally associated with men or women. Nevertheless, these coexist with other neutral sports. Girls’ practice was more diverse, while boys’ profile was more resistant to changing classic patterns. Specific strategies are needed to make boys become more interested in typically female activities

Accessible triplet excited states in the photoisomerization of allenes with extended conjugation

A series of bidentate allene- and enyne-containing ligands have been synthesized and the photochemical properties of their rhenium(I) complexes have been studied. These complexes exhibit facile isomerization of the conjugated double bonds upon ambient light exposure. Simulations unveiled a very efficient intersystem crossing and the consequent key role of the triplet states in the observed photochemistry of these substrates upon rhenium(I) complexation.Agencia Estatal de Investigación | Ref. CTQ2017-85919-RXunta de Galicia | Ref. EC431C 2021/4

Comparisons of Production Costs and Profit of Three Different Technology Levels of Papaya Production in Tabasco, Mexico

The survey was carried out from September 2006 to January 2007 in three papaya production sites located in main papaya production zones in Tabasco; SE Mexico. There are differences in size of the cultivated area, in the yield of the papaya as well as in production costs and profit, according to the different technology levels in the farming systems: low, medium and high technology cultivation level. The financial evaluations were carried out in three sites with different productive technologies. The comparison of the agronomic and economic traits results for low technology level in: V AN of 2359.00 USD, BCR in 1.9 and an equilibrium point of 3750.00 USD, TIR of 0.25. In order to avoid loses, a quantity of 10714 kg papaya should be sold. In medium technology VAN is 1605.10 USD, BCR is 1.7, TIR 0.20 and the equilibrium point is 12800.00 USD. 36571 kg of papaya should be yearly sold. In high technology level VAN is 11749.40, BCR is 2.73, TIR 0.43 and the equilibrium point is 12187.50 USD, 34821 kg papaya should be sold yearly. The indicators showed that all three levels are profitable and economically viable

Conocimientos sobre cáncer de mama en pacientes de un consultorio médico

Introducción: el cáncer de mama representa un problema de salud pública; es la neoplasia maligna más frecuente en la mujer y también puede manifestarse en el sexo masculino, aunque en menor cuantía. Resulta necesaria la actualización sobre temas relacionados con esta enfermedad para lograr su prevención. Objetivo: caracterizar el nivel de conocimientos sobre cáncer de mama en un grupo de pacientes pertenecientes al Consultorio Médico de la Familia 20 del municipio Morón, Ciego de Ávila.Método: se realizó un estudio observacional, descriptivo, transversal en el periodo comprendido entre septiembre y octubre de 2020. Se trabajó con la totalidad del universo, el cual estuvo constituido por 81 pacientes. Se utilizó la estadística descriptiva.Resultados: el 60,5 % de los casos representó al sexo femenino.  Las personas adultas mayores de 50 años representaron el 43,2 %. La ausencia de la lactancia materna y el tabaquismo estuvieron presentes en el 33,3 % y el 25,9 % de los pacientes respectivamente. En cuanto al nivel de conocimientos, el 70,4 % era inadecuado. Conclusiones: se logró identificar un bajo nivel de conocimientos en las personas encuestadas sobre temas relacionados con el cáncer de mama

MÉTODOS ACTIVOS DE ENSEÑANZA ASOCIADOS A LA ANALÍTICA DEL APRENDIZAJE

En el proceso de enseñanza aprendizaje el componente, método, es fundamental para que los alumnos puedan apropiarse de los saberes y de ellos, los activos, propician una participación protagónica de los estudiantes. El objetivo de esta investigación es caracterizar las actividades de la plataforma interactiva en la asignatura Herramientas informáticas para, desde los métodos activos de enseñanza, garantizar un crecimiento en los estudiantes. La metodología utilizada fue la cuantitativa y los métodos teóricos fueron el inductivo deductivo y analítico sintético. Desde la práctica predominaron los métodos estadísticos matemáticos, tanto descriptivos como inferenciales. Los resultados fundamentales estuvieron en la wiki los puntajes fueron altos, debido al trabajo cooperativo que realizaron los alumnos en esta actividad, los foros tuvieron puntuaciones homogéneas y la valoración de los docentes es que el trabajo colaborativo logrado en el componente autónomo provoca un crecimiento, consiente y duradero de los saberes en los alumnos, el taller, la calidad de la nota es más baja que en las dos actividades anteriores y a criterio de los docentes esta actividad colaborativa y cooperativa está considerada con alta dificultad por la cantidad de veces que los alumnos tiene que reunirse para la toma de decisiones y críticas a sus colegas. En sentido general se puede concluir que se ha caracterizado las actividades de la plataforma interactiva en la asignatura Herramientas informáticas la cual, a través de los métodos activos de enseñanza, utilizados denotaron un crecimiento en los estudiantes

High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease

Cyclophilins (Cyps) are ubiquitous proteins that belong to the immunophilins family consistently associated with inflammatory and cardiovascular diseases. While levels of CypA have been extensively studied, less data are available for other Cyps. The purpose of this case-control study was to determine the relationship of Cyps (A, B, C and D) with coronary artery disease (CAD) and eight inflammation markers. Serum levels of Cyps, interleukins and metalloproteinases were measured in serum collected from 84 subjects. Participants were divided into two sub-groups based on CAD diagnosis: 40 CAD patients and 44 control volunteers. Serum levels of CypA, CypB and CypC, IL-1β and IL-6 were significantly higher in CAD patients. Bivariate correlation analysis revealed a significant positive correlation between Cyps and several blood and biochemical parameters. When the ability of Cyps levels for CAD diagnosis was evaluated, higher sensitivity and selectivity values were obtained with CypC (c-statistic 0.891, p < 0.001) indicating that it is a good marker of CAD disease, while less conclusive results were obtained with CypA (c-statistic 0.748, p < 0.001) and CypB (c-statistic 0.655, p < 0.014). In addition, significant correlations of traditional CAD risk factors and CypC were observed. In summary, high levels of CypC are a risk factor for CAD and therefore it can be proposed as a new biomarker for this disease.This work could not have been done without the invaluable collaboration of the staff at the Servicio Vixilancia da Saude from Universidad de Santiago de Compostela (Andrea Vidal Dopazo) and at the Cardiology Department, Hospital Universitario Lucus Augusti (Maria Jesús Basanta-Castro, Maria del Carmen Cabarcos Leal, Clara Jimenez-Serrano, Leonor Ortega- Fernández, Maria Jesus Palacios Pool, Sofía Seco-Aldegunde). The research leading to these results has received funding from the following FEDER cofunded-grants. From Conselleria de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia, 2017 GRC GI-1682 (ED431C 2017/01). From CDTI and Technological Funds, supported by Ministerio de Economía, Industria y Competitividad, AGL2016-78728-R (AEI/FEDER, UE), ISCIII/PI16/01830, ISCIII/PI16/01816 and RTC-2016-5507-2, ITC-20161072. From European Union POCTEP 0161-Nanoeaters -1-E-1, Interreg AlertoxNet EAPA-317-2016, Interreg Agritox EAPA-998-2018, and H2020 778069-EMERTOX. Sandra Gegunde was supported by a fellowship from FIDIS, Spain

Improving area center robot navigation using a novel range scan segmentation method

When using raw 2D range measures to delimit the border for the free area sensed by a robot, the noise makes the sensor to yield a cloud of points, which is an imprecise border. This vagueness pose some problems for robot navigation using area center methods, due to free area split points locations. The basic method, when locating split points, does not take into account environmental features, only the raw cloud of points. In order to determine accurately such environmental features we use a novel range scan segmentation method. This method has the interesting characteristic of being adaptive to environment noise, in the sense that we do not need to fix noise standard deviation, even different areas of the same scan can have different deviations, e. g. a wall besides a hedge. Procedure execution time is in the order of milliseconds for modern processors. Information about interesting navigational features is used to improve area center navigation by means of determining safer split points and developing the idea of dynamic split point. A dynamic split point change its position to a new feature if this new feature is considered more dangerous than the one marked by the split point

Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly

Most of acromegaly is caused by a sporadic somatotropinoma and a couple of novel gene mutations responsible for somatotropinoma have recently been reported. To determine the cause of sporadic somatotropinoma in Japanese patients, we analyzed 61 consecutive Japanese patients with somatotropinoma without apparent family history. Comprehensive genetic analysis revealed that 31 patients harbored guanine nucleotide-binding protein, alpha stimulating (GNAS) mutations (50.8%) and three patients harbored aryl hydrocarbon receptor interacting protein (AIP) mutations (4.9%). No patients had G protein-coupled receptor 101 (GPR101) mutations. The patients in this cohort study were categorized into three groups of AIP, GNAS, and others and compared the clinical characteristics. The AIP group exhibited significantly younger age at diagnosis, larger tumor, and higher nadir GH during oral glucose tolerance test. In all patients with AIP mutation, macro- and invasive tumor was detected and repetitive surgery or postoperative medical therapy was needed. One case showed a refractory response to postoperative somatostatin analogue (SSA) but after the addition of cabergoline as combined therapy, serum IGF-I levels were controlled. The other case showed a modest response to SSA and the switching to cabergoline monotherapy was also effective. These data suggest that although resistance to SSA has been reported in patients with AIP mutations, the response to dopamine agonist (DA) may be retained. In conclusion, the cause of sporadic somatotropinoma in Japanese patients was comparable with the previous reports in Caucasians, patients with AIP mutations showed unique clinical characteristics, and DA may be a therapeutic option for patients with AIP mutations

Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study

Objectives: Asthma has not been extensively studied in low-income and middle-income countries, where risk factors and access to treatment may differ from more affluent countries. We aimed to identify the prevalence of asthma and local risk factors in Havana, Cuba.Setting: Four municipalities in Havana, Cuba.Participants: A population-based cohort study design of young children living in Havana, Cuba. Children were recruited from primary care centres at age 12–15 months.Primary and secondary outcome measures: Data on wheeze in the past 12 months, asthma treatment and environmental exposures collected regularly until the age of 6 years, when forced expiratory volume in 1 s (FEV1) and reversibility to aerosolised salbutamol were also measured.Results: 1106 children provided data at the age of 6 years old. The prevalence of wheeze in the previous 12 months was 422 (38%), and 294 (33%) of the study population had bronchodilatation of 12% or more in FEV1 after administration of inhaled salbutamol. In the previous 12 months, 182 (16%) of the children had received inhaled corticosteroids, 416 (38%) salbutamol inhalers and 283 (26%) a course of systemic steroids.Wheeze in the first year and a family history of asthma were both positively associated with bronchodilatation to inhaled salbutamol (1.94%; 95% CI 0.81 to 3.08 and 1.85%; CI 0.14 to 3.57, respectively), while paracetamol use in the first year was associated with wheeze at 6 years (OR 1.64, 95% CI 1.14 to 2.35). There were large differences in FEV1, bronchodilatation and risk of wheeze across different geographical areas.Conclusions: Asthma is common in young children living in Havana, and the high prevalence of systemic steroids administrated is likely to reflect the underuse of regular inhaled corticosteroids. If replicated in other comparable low-income and middle-income countries, this represents an important global public health issue