329 research outputs found

    The Share of Employee Benefits Sports Content on the Quality of Life of Employees with Predominantly Sedentary

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    Tato bakalářská práce je zaměřena na problematiku nedostatečnosti v pohybových činnostech u zaměstnanců se sedavým zaměstnáním, špatně nastavených stereotypů lidského těla, nedostatku pohybových aktivit a pohybu samotného. Zabývá se zdravotními problémy plynoucími z nedostatku pohybu a následným řešením těchto problémů, jak ze strany samotného zaměstnance, tak ze strany zaměstnavatele, pomocí zaměstnaneckých benefitů. Hlavním účelem práce je pomoci a zlepšit kvalitu fyzického stavu lidí se sedavým zaměstnáním.This bachelor‘s thesis is focused on matters of insufficiency of movement activities of employees with sedentary jobs, wrongly adjusted stereotypes of human body, lack of exercise activities and movement itself. It deals with health problems resulting from the lack of exercise followed by solution to these problems by the employee himself and by the employer through the employee benefits. The main purpose of this thesis is to help and improve quality of physical condition of people with sedentary jobs.

    Environmental aspects of CNG vehicles

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    Tato bakalářská práce je zaměřená na téma environmentální aspekty provozu vozů na CNG. Nejprve je představen zemní plyn jako palivo pro spalovací motory. Jsou zhodnoceny jeho výhody a nevýhody. Dále jsou popsány jednotlivé spalovací systémy a komponenty motoru na stlačený zemní plyn. Hlavní část práce je zaměřená na ekologii. Je popsán vliv na životní prostředí u spalování stlačeného zemního plynu v porovnání s konvenčními palivy. Toto porovnání je provedeno také podle objektivnější Well to Wheels analýzy.This bachelor‘s thesis is focused on matter of environmental aspects of cars powered by CNG. At first natural gas is introduced as a fuel for combustion engines. In the next step pros and cons are evaluated. Then there are described individual combustion systems and components of engine powered by natural gas. The main part of this thesis is focused on ecology. There is mentioned the impact on environment, comparing the impact of natural gas with other conventional fuels. This comparison is realised through the more objective Well to Wheels analysis as well.

    Production technology of a lifting equipment for tractor cooler

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    Diplomová práce se zabývá návrhem výrobní technologie pro zdvihací zařízení chladiče traktoru. Toto zařízení slouží k usnadnění montáže chladiče při výrobě traktoru. V první části jsou popsány druhy zdvihacích zařízení. V následujících kapitolách jsou navrženy výrobní technologie, stroje a nástroje pro výrobu dané součásti. Jsou navrženy materiály a výrobní postupy pro zhotovení zadané součásti. V závěru jsou pro navržený způsob výroby vypracovány technologické postupy, spočítána časová náročnost a provedeno technicko-ekonomické zhodnocení výroby.The thesis focuses on production technology of the lifting equipment for a tractor cooler. This device is used in order to ease the installation of a cooler during the manufacturing of a tractor. In the first chapter, various types of the lifting equipment are described. In the following chapters manufacturing methods, machines and tools for the production of the specific component are described. Furthermore, materials and manufacturing processes for the complementation of the specific component are proposed. In the conclusion, the methods for the manufacturing are suggested, the timescale is calculated and the technical-economical evaluation is performed.

    Improvement of Live Variable Analysis Using Points-to Analysis

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    Jazyky, jako je C, hojně využívají práce s ukazateli. Implemetace dynamických datových struktur vázaných ukazateli a operací nad nimi však není jednoduchá - významně zvyšuje rizika zanášení chyb do zdrojových kódů. Jedna z cest, jakými lze eliminovat množství těchto chyb, je použití statické analýzy. Tato práce se tedy zabývá vylepšením architektury Code Listner, která nabízí rozhraní pro tvorbu statických analyzátorů. Vlastností tohoto rozhraní je, že poskytuje takovému analyzátoru k rozboru potřebné informace o programu - ku příkladu databázi proměnných, graf toku řízení čí graf volání funkcí. Součástí implementace Code Listeneru je také algoritmus pro analýzu živých proměnných, umožňující odstranit, neboli zabít proměnné, které nejsou v daném místě grafu toku řízení potřeba. Původní algoritmus ale nedovedl z důvodu bezpečnosti zabít žádné proměnné, na něž byla kdekoliv ve zdrojovém kódu vzata adresa. Předpokládalo se, že taková proměnná může být zpřístupněna pomocí reference kdekoliv v programu. Cílem práce tedy bylo navrhnout a implementovat algoritmus pro points-to analýzu, která dovede vyloučit existenci některých referencí v daném kontextu programu a umožní tedy zefektivnit analýzu živých proměnných.Languages such as C use pointers very heavily. Implementation of operations on dynamically linked structures is, however, quite difficult. This can cause the programmer to make more mistakes than usual. One method for dealing with this situation is to use the static analysis tools. This thesis elaborates on the extension to the Code Listener architecture which is an interface for building static analysis tools. Code Listener is able to construct a call-graph or a control flow graph for a given source code and send it to the analyzing tool. One ability of the architecture is that it can conduct the live variable analysis internally. It detects places in the control flow graph where some subset of variables may be killed. The problem was that every variable for which a pointer address was assigned could not been killed, before. This decision had been made because there was no assurance that the variable could never been used through the pointer. So the goal of this work was to design and incorporate a points-to analysis which is able to exclude some references from the set of considered pointers to improve the live variable analysis.

    Analysis of riboflavin/ultraviolet a corneal cross-linking by molecular spectroscopy

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    Corneal cross-linking (CXL) with riboflavin and ultraviolet A light is a therapeutic procedure to restore the mechanical stability of corneal tissue. The treatment method is applied to pathological tissue, such as keratoconus and induces the formation of new cross-links. At present, the molecular mechanisms of induced cross-linking are still not known exactly. In this study, we investigated molecular alterations within porcine cornea tissue after treatment with riboflavin and ultraviolet A light by surface enhanced Raman spectroscopy (SERS). For that purpose, after CXL treatment a thin silver layer was vapor-deposited onto cornea flaps. To explore molecular alterations induced by the photochemical process hierarchical cluster analysis (HCA) was used. The detailed analysis of SERS spectra reveals that there is no general change in collagen secondary structure while modifications on amino acid side chains are the most dominant outcome. The formation of secondary and aromatic amine groups as well as methylene and carbonyl groups were observed. Even though successful cross-linking could not be registered in all treated samples, Raman signals of newly formed chemical groups are already present in riboflavin only treated corneas

    The meaning of the demarcation line after riboflavin-UVA corneal collagen crosslinking

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    Introduction: The demarcation line (DL) observed since the pioneering crosslink (CLX) protocol at the posterior edge of the cross-linked stroma has been universally accepted as a therapeutic milestone of treatment. Numerous laboratory and clinical CXL studies demonstrate that a deeper DL is associated with a higher amount and saturation level of crosslinks, a more pronounced stiffening effect, and a more durable ectasia stability. Areas covered: A critical revision of laboratory, clinical, and analytical studies on the DL depth supports the significance of the DL as an evaluator of the performance of CLX procedures in terms of biomechanical efficacy and safety avoiding extensive experiments. A mechanical approach based on experimental data shows that the DL depth obtained with different CXL protocols relates with an asymptotic non-linear increasing function to the modified biomechanical corneal stiffness (elastic modulus). Expert opinion: The strong connection between the depth of the DL and the increase of the biomechanical efficacy can be explained by means of UV cross-linking chemical investigations demonstrating that only a limited amount of free reactive collagen residues is involved in the short-wave UV-mediated CXL. Thus, the CXL density can rise only up to an upper boundary value, i.e. the saturation value

    Laseranwendung in der Augenheilkunde

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    Die Augenheilkunde stellt eine der medizinischen Fachdisziplinen dar, die Laserstrahlung schon sehr früh einsetzten und heute bei verschiedenen Erkrankungen anwenden. Zur Diagnostik und Therapie der Glaukome, bei Netzhauterkrankungen, aber auch zur Behandlung von Fehlsichtigkeiten werden verschiedene Lasertypen erfolgreich eingesetzt.Ophthalmology represents a medical field where laser technology was established very early and where lasers are nowadays frequently used. In the diagnosis and treatment of glaucoma, for treatment of retinal disorders as well as for refractive surgery different types of lasers are used

    Corneal melting after collagen cross-linking for keratoconus: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Corneal collagen cross-linking is a rather new technique that uses riboflavin and ultraviolet A light for collagen fiber stabilization in keratoconus corneas. Other than reversible side effects, the preliminary results of corneal collagen cross-linking studies suggest that it is a rather safe technique. In this report, we demonstrate a case of corneal melting after corneal collagen cross-linking for keratoconus corneas associated with an acute inflammatory response.</p> <p>Case presentation</p> <p>A 23-year-old Caucasian man with keratoconus cornea stage 1 to 2 underwent uneventful corneal collagen cross-linking treatment according to the Dresden protocol. The next day the patient had intense photophobia, watering and redness of the eye, and his visual acuity was limited to counting fingers. Slit lamp biomicroscopy revealed severe corneal haze accompanied by non-specific endothelial precipitates following an acute inflammatory response. Mild inflammation could be detected in the anterior chamber. Moreover, the re-epithelialization process could barely be detected. His corneal state gradually deteriorated, resulting in descemetocele and finally perforation.</p> <p>Conclusion</p> <p>In this report, we present a case of a patient with corneal melting after standard corneal collagen cross-linking treatment for keratoconus corneas following an acute inflammatory response. Despite modifying postoperative treatment, elaboration of all apparent associated causes by the treating physicians and undergoing extensive laboratory testing, the patient developed descemetocele, which led to perforation. Our report suggests that further research is necessary regarding the safety of corneal collagen cross-linking in keratoconus corneas.</p

    Improving precision for detecting change in the shape of the cornea in patients with keratoconus

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    To investigate a method for precision analysis to discriminate true corneal change from measurement imprecision in keratoconus (KC). Thirty patients with KC and 30 healthy controls were included. Coefficients of repeatability and limits of agreement (LOA) were compared using multiple measurements for inter-observer and inter-device agreement with the Pentacam HR, Orbscan IIz, and Tomey Casia SS-1000. Correlation of repeated measurements was evaluated using a linear mixed effect model (also called random effect model). A formula was derived for the theoretical expected change in precision and compared with measured change. Correlation between measurements from the same eye was small (R = 0.13). The 99.73% LOA (3 SD) of the mean of three measurements, provided better precision than 95% LOA (2 SD) of single cut-off values as expected from statistical theory for uncorrelated measurements for evidence of a significant change in corneal shape in patients with keratoconus. This enabled the determination of cut-off values for the detection of true change in corneal shape. The mean of three repeated measurements will provide better precision when there is minimal correlation. Three (rather than two) standard deviations provides a precise estimate of the LOA within or between observers and can be used as a reliable measure for identifying stage-independent corneal shape changes (progression) in keratoconus
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