Lipocalin 2 protects from lung tumorigenesis associated with gut microbiota alterations

https://openworks.mdanderson.org/sumexp22/1112/thumbnail.jp

Supersymmetric Sum Rules for Electromagnetic Multipoles

We derive model independent, non-perturbative supersymmetric sum rules for the magnetic and electric multipole moments of any theory with N=1 supersymmetry. We find that in any irreducible N=1 supermultiplet the diagonal matrix elements of the l-multipole moments are completely fixed in terms of their off-diagonal matrix elements and the diagonal (l-1)-multipole moments.Comment: 10 pages, plain Te

κ−(BEDT−TTF)2X\kappa-(BEDT-TTF)_2X organic crystals: superconducting versus antiferromagnetic instabilities in an anisotropic triangular lattice Hubbard model

A Hubbard model at half-filling on an anisotropic triangular lattice has been proposed as the minimal model to describe conducting layers of $\kappa-(BEDT-TTF)_2X$ organic materials. The model interpolates between the square lattice and decoupled chains. The $\kappa-(BEDT-TTF)_2X$ materials present many similarities with cuprates, such as the presence of unconventional metallic properties and the close proximity of superconducting and antiferromagnetic phases. As in the cuprates, spin fluctuations are expected to play a crucial role in the onset of superconductivity. We perform a weak-coupling renormalization-group analysis to show that a superconducting instability occurs. Frustration in the antiferromagnetic couplings, which arises from the underlying geometrical arrangement of the lattice, breaks the perfect nesting of the square lattice at half-filling. The spin-wave instability is suppressed and a superconducting instability predominates. For the isotropic triangular lattice, there are again signs of long-range magnetic order, in agreement with studies at strong-coupling.Comment: 4 pages, 5 eps figs, to appear in Can. J. Phys. (proceedings of the Highly Frustrated Magnetism (HFM-2000) conference, Waterloo, Canada, June 2000

Parkinson's disease may disrupt overlapping subthalamic nucleus and pallidal motor networks.

There is an ongoing debate about differential clinical outcome and associated adverse effects of deep brain stimulation (DBS) in Parkinson's disease (PD) targeting the subthalamic nucleus (STN) or the globus pallidus pars interna (GPi). Given that functional connectivity profiles suggest beneficial DBS effects within a common network, the empirical evidence about the underlying anatomical circuitry is still scarce. Therefore, we investigate the STN and GPi-associated structural covariance brain patterns in PD patients and healthy controls. We estimate GPi's and STN's whole-brain structural covariance from magnetic resonance imaging (MRI) in a normative mid- to old-age community-dwelling cohort (n = 1184) across maps of grey matter volume, magnetization transfer (MT) saturation, longitudinal relaxation rate (R1), effective transversal relaxation rate (R2*) and effective proton density (PD*). We compare these with the structural covariance estimates in patients with idiopathic PD (n = 32) followed by validation using a reduced size controls' cohort (n = 32). In the normative data set, we observed overlapping spatially distributed cortical and subcortical covariance patterns across maps confined to basal ganglia, thalamus, motor, and premotor cortical areas. Only the subcortical and midline motor cortical areas were confirmed in the reduced size cohort. These findings contrasted with the absence of structural covariance with cortical areas in the PD cohort. We interpret with caution the differential covariance maps of overlapping STN and GPi networks in patients with PD and healthy controls as correlates of motor network disruption. Our study provides face validity to the proposed extension of the currently existing structural covariance methods based on morphometry features to multiparameter MRI sensitive to brain tissue microstructure

Production and evaluation of leukocyte- and thrombocyte-rich fibrin membranes in birds

The aim of this study was the preparation and histological evaluation of Leukocyte- and Thrombocyte-Rich Fibrin (L-TRF) membranes obtained from the blood of four bird species. Forty adult healthy birds were divided into four groups of equal size: G1 – macaws, G2 – domestic chickens, G3 – parrots, G4 – toco toucans. A total of 0.5 mL of blood was collected from each bird, put into a glass tube without anticoagulant and centrifuged at 3000 rpm for 10 min. L-TRF membranes produced after compression of the clot were processed for histological analysis. The ratio of thrombocytes/area was not significantly different among Groups G2, G3 and G4, but a significant difference was found between Groups G1 and G2 with the highest thrombocyte concentration/area in G1. The groups did not differ statistically in the number of leukocytes/area. The fibrin-to-cells ratio did not vary statistically among Groups G1, G2 and G3, but this ratio was significantly higher in Group G4 than in the other groups. The thrombocyte-to-leukocyte ratio was the highest in Group G1, but it did not differ among Groups G2, G3 and G4. In conclusion, the centrifugation protocol allowed the production of L-TRF membranes in the four bird species studied. Histologically, cell ratios were analogous in domestic chickens and parrots, and macaws had the highest ratio of thrombocytes

Galactic Bulge Microlensing Optical Depth from EROS-2

We present a new EROS-2 measurement of the microlensing optical depth toward the Galactic Bulge. Light curves of $5.6\times 10^{6}$ clump-giant stars distributed over $66 \deg^2$ of the Bulge were monitored during seven Bulge seasons. 120 events were found with apparent amplifications greater than 1.6 and Einstein radius crossing times in the range 5 {\rm d}. This is the largest existing sample of clump-giant events and the first to include northern Galactic fields. In the Galactic latitude range 1.4\degr<|b|<7.0\degr, we find $\tau/10^{-6}=(1.62 \pm 0.23)\exp[-a(|b|-3 {\rm deg})]$ with $a=(0.43 \pm0.16)\deg^{-1}$. These results are in good agreement with our previous measurement, with recent measurements of the MACHO and OGLE-II groups, and with predictions of Bulge models.Comment: accepted A&A, minor revision

Avaliação eletroneuromiográfica de lesões nervosas periféricas traumáticas dos membros pélvicos em gatos

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Não-união tarsometarsiana em Urubu-Rei (Sarcoramphus papa)

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