Detection of Point Sources in Cosmic Ray Maps using the Mexican Hat Wavelet Family

An analysis of the sensitivity of gaussian and mexican hat wavelet family filters to the detection of point sources of ultra-high energy cosmic rays was performed. A source embedded in a background was simulated and the number of events and amplitude of this source was varied aiming to check the sensitivity of the method to detect faint sources with low statistic of events.Comment: Proceedings of the Second International Symposium on Strong Electromagnetic Fields and Neutron Stars (Havana, Cuba, 2011). 6 pages, 4 figure

Wavelets Applied to the Detection of Point Sources of UHECRs

In this work we analyze the effect of smoothing maps containing arrival directions of cosmic rays with a gaussian kernel and kernels of the mexican hat wavelets of orders 1, 2 and 3. The analysis is performed by calculating the amplification of the signal-to-noise ratio for several anisotropy patterns (noise) and different number of events coming from a simulated source (signal) for an ideal detector capable of observing the full sky with equal probability. We extend this analysis for a virtual detector located within the array of detectors of the Pierre Auger Observatory, considering an acceptance law.Comment: 9 pages, 8 figures. Proceedings of the Young Researchers Meeting, 2010. Available in: http://www.ifi.unicamp.br/physicae/ojs-2.1.1/index.php/physicae/article/view/191; Physicae, Proceedings of the Young Researchers Meeting, Vol 1, 201

Differential Attraction Of Drosophilids To Banana Baits Inoculated With Saccharomyces Cerevisiae And Hanseniaspora Uvarum Within A Neotropical Forest Remnant

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Yeasts are a necessary requisite in the diet of most Drosophila species that, in turn, may vector their dispersal in natural environments. Differential attractiveness experiments and the isolation of yeasts consumed by Drosophila may be informative for characterizing this association. Hanseniaspora uvarum is among the most common yeast species isolated from Drosophila crops, with high attractiveness to drosophilids. Saccharorrtyces cerevisiae has been widely used to collect flies, and it allows broad sampling of almost. all local Drosophila species. Pronounced differences in the field concerning Drosophila attractivity to baits seeded with these yeast species have been previously reported. However, few explicit generalizations have. been. set. Since late fifties, no field experiments of. Drosophila attractivity were carried out. in.the Neotropical region, which is facing shifts in abiotic and biotic factors.. Our objective is to characterize preference behavior that mediates the interaction in the wild among Neotropical Drosophila species and yeasts associated with them. We want to set a broad generalization about drosophilids attracted to the se yeasts. Here we present the results of a differential attractiveness experiment we carried out in a natural Atlantic Rainforest fragment to assess the preferences of Drosophila species groups to baits inoculated with H. uvarum and S. cerevisiae. Methods. Both yeast species were cultured in GYMP broth and separately poured in autoclaved mashed banana that was left fermenting. In the field, we collected drosophilids over five arrays of three different baits: non-inoculated autoclaved banana and banana inoculated with each yeast. In the laboratory the drosophilids were sorted to five sets according to their external morphology and/or genitalia: tripunctata; guarani; exotic; and the remaining flies pooled in others. Results and Conclusions. Uninoculated banana baits attracted virtually no flies. We found significant departures from random distribution over the other two baits (1:1 proportion) for all sets, except the pooled others. Flies of the sets willistoni and exotic preferred H. uvarum over S. cerevisiae, while the remaining sets were more attracted to S. cerevisiae. Previously various authors reported similar patterns in attraction experiments with S. cerevisiae and H. uvarum. It is also noteworthy that both yeast species have been isolated from natural substrates and crops of Drosophila species. Taken together, these results suggest that the preferences among Drosophila species groups may be reflecting deep and stable relations with yeast species in natural environments. They can be summarized as: forest dwelling species from subgenus Drosophila (such as tripunctata and guarani groups) are attracted to banana baits seeded with S. cerevisiae; while exotic (as D. melanogaster) and subgenus Sophophora species are preferentially attracted to baits seeded with H. uvarum.5Coordenacao de Aperfeicoamento de Pessoal do Ensino Superior (CAPES) [PRODOC 2709/2010]Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [308285/2014-0, 457499/2014-1, 312066/2014-7]Fundo de Apoio ao Ensino, a Pesquisa e Extensao da Unicamp (FAEPEX-PEC2012) [1578/12]Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2012/03144-0, 2014/03791-1]Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG) [APQ-01525-14]Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Axion-like particles and high-energy gamma rays: interconversion revisited

Axion-like particles (ALPs) are hypothetical entities often invoked to solve various problems in particle physics to cosmology. They are one of the most promising candidates to explain the elusive dark matter. A way to search for ALPs is through their effects on photons. In the presence of external magnetic fields, ALPs and photons can convert into one another, leading to measurable signals. In this contribution we present results of Monte Carlo simulations of ALP-photon interconversion in magnetised environments. We focus on high-energy gamma rays with TeV energies travelling over cosmological distances. We include a full treatment of the intergalactic electromagnetic cascades triggered by the gamma rays. Finally, we discuss the impact of this improved treatment of the propagation for current and future ALP searches.Comment: Presented at the 38th International Cosmic Ray Conference (ICRC2023

Significado geológico de las anomalías geofísicas del suroeste del macizo ofiolítico Moa-Baracoa (Cuba Ooriental)

A partir del procesamiento e interpretación de la información geofísica y geológica del suroeste del macizo ofiolítico Moa-Baracoa, se delimitaron nuevas áreas de desarrollo de lateritas Fe+Ni+Co, y de otros tipos de rocas, se esclarecieron aspectos relacionados con los procesos que tienen lugar en los diferentes tipos de rocas, tales como grado de meteorización, arcillosidad, contenido organógeno y acidez. También se evidenciaron las principales deformaciones tectónicas en las ofiolitas y rocas asociadas, algunas de ellas ya reportadas y otras propuestas en esta investigación, las cuales deben ser objetos de estudio en futuras investigaciones en el territorio. Con la combinación del comportamiento del campo magnético y las características aerogamma espectrométricas, se delimitaron zonas con predominio en superficie y en la profundidad de rocas serpentinizadas y por ende las variaciones de espesores de las mismas y de los dos niveles fundamentales del corte ofiolítico en esta región. También se definió el basamento de las rocas que afloran

Mechanochemically Synthesized Supported Magnetic Fe-Nanoparticles as Catalysts for Efficient Vanillin Production

Magnetically separable nanocatalysts were synthesized by incorporating iron nanoparticles on a mesoporous aluminosilicate (Al-SBA-15) through a mechanochemical grinding pathway in a single step. Noticeably, magnetic features were achieved by employing biomass waste as a carbon source, which additionally may confer high oxygen functionalities to the resulting material. The resulting catalysts were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy, scanning electron microscopy, porosimetry, and magnetic susceptibility. The magnetic nanocatalysts were tested in the selective oxidative cleavage reaction of isoeugenol and vanillyl alcohol to vanillin. As a result, the magnetic nanocatalysts demonstrated high catalytic activity, chemical stability, and enormous separation/reusability qualities. The origin of catalytic properties and its relationship with the iron oxide precursor were analyzed in terms of the chemical, morphological, and structural properties of the samples. Such analysis allows, thus, to highlight the superficial concentration of the iron entities and the interaction with Al as key factors to obtain a good catalytic response

Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin

A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent cell signaling pathway. We determined high-resolution crystal structures of free EcTI (at 1.75 angstrom) and complexed with bovine trypsin (at 2 angstrom). High quality of the resulting electron density maps and the redundancy of structural information indicated that the sequence of the crystallized isoform contained 176 residues and differed from the one published previously. the structure of the complex confirmed the standard inhibitory mechanism in which the reactive loop of the inhibitor is docked into trypsin active site with the side chains of Arg64 and Ile65 occupying the S1 and S1' pockets, respectively. the overall conformation of the reactive loop undergoes only minor adjustments upon binding to trypsin. Larger deviations are seen in the vicinity of Arg64, driven by the needs to satisfy specificity requirements. A comparison of the EcTI-trypsin complex with the complexes of related Kunitz inhibitors has shown that rigid body rotation of the inhibitors by as much as 15 degrees is required for accurate juxtaposition of the reactive loop with the active site while preserving its conformation. Modeling of the putative complexes of EcTI with several serine proteases and a comparison with equivalent models for other Kunitz inhibitors elucidated the structural basis for the fine differences in their specificity, providing tools that might allow modification of their potency towards the individual enzymes.United States Department of Energy, Office of Science, Office of Basic Energy SciencesCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)National Institutes of Health, National Cancer Institute, Center for Cancer ResearchNCI, Ctr Canc Res, Macromol Crystallog Lab, Frederick, MD 21701 USAUniversidade Federal de São Paulo, Dept Bioquim, São Paulo, BrazilInst Butantan, Lab Bioquim & Biofis, Unidade Sequenciamento Prot & Peptideos, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Bioquim, São Paulo, BrazilUnited States Department of Energy, Office of Science, Office of Basic Energy Sciences: W-31-109-Eng-38FAPESP: 09/53766-5Web of Scienc

Thermal and light irradiation effect on the electrocatalytic performance of Hemoglobin modified Co3O4-g-C3N4 nanomaterials for oxygen evolution reaction

The oxygen evolution reaction (OER) plays a key role in the water splitting process and a high energy conversion efficiency is essential for the definitive advance of hydrogen-based technologies. Unfortunately, the green and sustainable development of electrocatalysts for water oxidation is nowadays a real challenge. Herein, a successful mechanochemical method is proposed for the synthesis of a novel hemoglobin (Hb) modified Co3O4/g-C3N4 composite nanomaterial. The controlled incorporation of cobalt entities as well as Hb functionalization, without affecting the g-C3N4 nanoarchitecture, was evaluated using different physicochemical techniques, such as X-ray diffraction, N2-physisorption, scanning electron microscopy, UV-visible spectroscopy and X-ray photoelectron spectroscopy. The beneficial effect of the resulting ternary bioconjugate together with the influence of the temperature and light irradiation was investigated by electrochemical analysis. At 60 °C and under light exposition, this electrocatalyst requires an overpotential of 370 mV to deliver a current density of 10 mA·cm−2, showing a Tafel slope of 66 mV·dec−1 and outstanding long-term stability for 600 OER cycles. This work paves a way for the controlled fabrication of multidimensional and multifunctional bio-electrocatalysts

Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro

Oxidative modification of low-density lipoprotein (LDL) represents an important factor in atherogenesis. In the present study, we have investigated the antioxidant capability of diphenyl diselenide (PhSe)2, a simple organoseleno compound, against copper (Cu2+) and peroxyl radical-induced human LDL oxidation in vitro. In initial studies using human serum, (PhSe)2 caused a dose-dependent inhibition of Cu2+-induced lipid peroxidation, which was correlated to thiol consumption. (PhSe)2 increased lipid peroxidation lag phase and decreased lipid peroxidation rate in isolated human LDL, evaluated by measuring both conjugated diene (CD) and thiobarbituric acid reactive substances (TBARS) levels. Consistent with these observations, (PhSe)2 showed a marked inhibitory effect on 2,2-azobis(2-amidinopropane dihydrochloride) (AAPH)-induced oxidation of LDL or parinaric acid (PnA) incorporated into LDL. (PhSe)2 also displayed a dose-dependent protective effect against Cu2+-induced lipid peroxidation in rat aortic slices. Interestingly, besides the antioxidant effects of (PhSe)2 toward the lipid moieties of LDL, which was related to its thiol-peroxidase activity, protein moieties from human isolated LDL were also protected against Cu2+-induced oxidation. The results presented herein are the first to show that (i) (PhSe)2 inhibits lipid peroxidation in human isolated LDL in vitro, (ii) this phenomenon is related to its thiol-peroxidase activity, and (iii) this chalcogen also prevents the oxidation of protein moieties of human LDL. Taken together, such data render (PhSe)2 a promising molecule for pharmacological studies with respect to the atherogenic process.http://www.sciencedirect.com/science/article/B6T12-4S21TS2-1/1/38250cf8bae4a4195ccd8905cf5c2a8