928 research outputs found

    Compensation Theory: Can Club Soccer Players Appropriately Balance Energy Intake and Output in and out of Season?

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    Obesity is a worldwide epidemic affecting both adults and children. Obesity and overweight prevalence is increasing, with a corresponding decline in physical fitness and general physical activity level (McHugh, 2010). The college setting presents an important opportunity for health promotion during a critical developmental stage for weight gain (Nelson et al., 2007). While exercising and a balanced diet are the basis of most obesity-prevention campaigns, little research has been done on how physical exercise may increase food consumption. The purpose of this study was to examine whether college club soccer players can appropriately balance energy intake and output in and out of season. A convenience sample of twenty-four college students (14 males and 10 females), at a midsized southeastern university between the ages of 18 and 23 years participated in the study. Self-reported anthropometrics and three-day food logs were obtained. Participants were given accelerometers to be worn under clothes on right side of hip for seven days. Food logs and accelerometers were analyzed one time during season and one month post season to receive normal training week and normal out of season readings for food consumption and activity levels. The average calories consumed increased from 1885 kcal/day in season to 1937 kcal/day out of season. The average calories burned decreased from 479.39 kcal/day in season to 451.46 out of season. There were no significant differences for physical activity besides a significant decrease in Total Vigorous Time in minutes. Coaches and dietitians need to encourage and educate athletes on healthier food choices and knowledge on energy balance, so during the off season athletes do not hinder their performance by being out of shape or overweight. More studies are needed to examine compensatory effects with different populations with both starting and ending exercise programs

    Static magnetic fields, blood and genes: an intriguing relationship.

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    Commentary to:Static magnetic fields induce blood flow decrease and platelet adherence in tumor microvesselsSebastian Strieth, Donata Strelczyk, Martin E. Eichhorn, Marc Dellian, Siiri Luedemann , Jurgen Griebel, Matthias Bellemann, Alexander Berghaus , Gunnar Bri

    Multiparameter quantum estimation of noisy phase shifts

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    Phase estimation is the most investigated protocol in quantum metrology, but its performance is affected by the presence of noise, also in the form of imperfect state preparation. Here we discuss how to address this scenario by using a multiparameter approach, in which noise is associated to a parameter to be measured at the same time as the phase. We present an experiment using two-photon states, and apply our setup to investigating optical activity of fructose solutions. Finally, we illustrate the scaling laws of the attainable precisions with the number of photons in the probe state

    The Effect of Chemical Composition of Biological Solutions on the Tribocorrosive Behavior and Synergistic Wear of Titanium Grade V Alloys for Biomedical Applications

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    Currently, the impact of tribocorrosion on medical devices such as dental implants has achieved notable effects since tribocorrosion is directly correlated with the longevity of the prosthesis. In a scenario where the phenomenon involves several variables, both from the tribological and chemical fields, this work aims to investigate the effect of the chemical compositions of biological solutions on the coupling of titanium grade V-alumina. The experimental tests were performed by a reciprocating tribometer equipped with a potentiostat and by a confocal/interferometric laser microscope connected with high-performance software for particle and wear analysis. The latter was evaluated by the synergistic approach, which is commonly adopted in the scientific community, as the sum of mechanical and synergistic effects. The results underlined that sodium lactate induced the greatest volume loss as much as the greatest tribocorrosive current and friction coefficient. On the other hand, the presence of salts such as sodium chloride and sodium bicarbonate also influenced the tribocorrosive response of titanium grade V alloys. In conclusion, the analytical equation considered for synergistic wear was modified by the introduction of a novel coefficient derived from the direct relationship between the friction coefficient and synergy and compared with the experimental data, providing a determination coefficient (R2) of 0.89

    Quantum sensors for dynamical tracking of chemical processes

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    Quantum photonics has demonstrated its potential for enhanced sensing. Current sources of quantum light states tailored to measuring, allow to monitor phenomena evolving on time scales of the order of the second. These are characteristic of product accumulation in chemical reactions of technologically interest, in particular those involving chiral compounds. Here we adopt a quantum multiparameter approach to investigate the dynamic process of sucrose acid hydrolysis as a test bed for such applications. The estimation is made robust by monitoring different parameters at once

    A New Methodology of Viewing Extra-Axial Fluid and Cortical Abnormalities in Children with Autism via Transcranial Ultrasonography

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    Background: Autism spectrum disorders (ASDs) are developmental conditions of uncertain etiology which have now affected more than 1% of the school-age population of children in many developed nations. Transcranial ultrasonography (TUS) via the temporal bone appeared to be a potential window of investigation to determine the presence of both cortical abnormalities and increased extra-axial fluid (EAF). Methods: TUS was accomplished using a linear probe (10–5 MHz). Parents volunteered ASD subjects (N = 23; males 18, females 5) for evaluations (mean = 7.46 years ± 3.97 years), and 15 neurotypical siblings were also examined (mean = 7.15 years ± 4.49 years). Childhood Autism Rating Scale (CARS2(®)) scores were obtained and the ASD score mean was 48.08 + 6.79 (Severe). Results: Comparisons of the extra-axial spaces indicated increases in the ASD subjects. For EAF we scored based on the gyral summit distances between the arachnoid membrane and the cortical pia layer (subarachnoid space): (1) <0.05 cm, (2) 0.05–0.07 cm, (3) 0.08–0.10 cm, (4) >0.10 cm. All of the neurotypical siblings scored 1, whereas the ASD mean score was 3.41 ± 0.67. We also defined cortical dysplasia as the following: hypoechoic lesions within the substance of the cortex, or disturbed layering within the gray matter. For cortical dysplasia we scored: (1) none observed, (2) rare hypoechogenic lesions and/or mildly atypical cortical layering patterns, (3) more common, but separated areas of cortical hypoechogenic lesions, (4) very common or confluent areas of cortical hypoechogenicity. Again all of the neurotypical siblings scored 1, while the ASD subjects’ mean score was 2.79 ± 0.93. Conclusion: TUS may be a useful screening technique for children at potential risk of ASDs which, if confirmed with repeated studies and high resolution MRI, provides rapid, non-invasive qualification of EAF, and cortical lesions

    Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells

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    The effects of Friend erythroleukemia cells on angiogenesis were studied in chick embryo chorioallantoic membrane assay and in human umbilical vein endothelial cells. In chorioallantoic membrane assay, the conditioned medium of Friend cells stimulated in vivo angiogenesis to an extent comparable to that observed with Prostaglandin El, used as positive control. Prostaglandin El added to conditioned medium of Friend cells did not further increase angiogenesis. Conditioned medium of Friend erythroleukemia cells also stimulated proliferation of human umbilical vein endothelial cells to an extent comparable to that observed with fetal bovine serum, used as positive control. Conditioned medium and fetal bovine serum together did not affect human umbilical vein endothelial cells proliferation, as compared to that observed when tested separately. These results seem to indicate that Friend erythroleukemia cells produce and secrete factors stimulating angiogenesis. These findings extend and confirm the hypothesis that successful angiogenesis is necessary for development of leukemia

    Effects of vitamin D-binding protein-derived macrophage-activating factor on human breast cancer cells

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    BACKGROUND: Searching for additional therapeutic tools to fight breast cancer, we investigated the effects of vitamin D-binding protein-derived macrophage activating factor (DBP-MAF, also known as GcMAF) on a human breast cancer cell line (MCF-7). MATERIALS AND METHODS: The effects of DBP-MAF on proliferation, morphology, vimentin expression and angiogenesis were studied by cell proliferation assay, phase-contrast microscopy, immunohistochemistry and western blotting, and chorioallantoic membrane (CAM) assay. RESULTS: DBP-MAF inhibited human breast cancer cell proliferation and cancer cell-stimulated angiogenesis. MCF-7 cells treated with DBP-MAF predominantly grew in monolayer and appeared to be well adherent to each other and to the well surface. Exposure to DBP-MAF significantly reduced vimentin expression, indicating a reversal of the epithelial/mesenchymal transition, a hallmark of human breast cancer progression. CONCLUSION: These results are consistent with the hypothesis that the known anticancer efficacy of DBP-MAF can be ascribed to different biological properties of the molecule that include inhibition of tumour-induced angiogenesis and direct inhibition of cancer cell proliferation, migration and metastatic potential
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