Agrorecreational ecoparks in the quarries territory as a new type of urban production (on the example of Kryvbas)

The article analyzes the main conditions of formation of agrorecreational ecoparks in the quarries territory, which no longer perform their initial functions. Agrorecreational ecoparks are regarded as a new type of urban development in combination with recreational function for industrial cities. Thus agrorecreational ecoparks are researched as structural elements of both agroproductive and recreational complexes of a country. Depending on types of activity there have been established main functional subzones and their interposition according to the exploitation mode and territory security. The planning structure of an agrorecreational ecopark locates the subzones of scientific use in the middle of a park, in the most accessible places as they are main attraction for visitors. Natural landscape of recreational use subzone adjoins the scientific zone; service centers and utility zones are located along the edges of the park thus creating a buffer area. The main groups of relief forms have been analyzed, which directly affect the planning structure of the researched parks. The main types of agrorecreational ecoparks in terms of relief forms have been identified; dimensional and spatial peculiarities of organization of such territories have been determined. In the context of a complex terrain and intensive soil erosion the major component of agrorecreational ecoterritories is geoplastic relief with drainage network (columbine), which determines precipitations run-off and the water regime of the park in general. The main notions and special features of landscape columbine and geoplastics (terracing) have been analyzed. The major types of agrolandscapes under the conditions of agrorecreational ecoparks formation have been established.The article analyzes the main conditions of formation of agrorecreational ecoparks in the quarries territory, which no longer perform their initial functions. Agrorecreational ecoparks are regarded as a new type of urban development in combination with recreational function for industrial cities. Thus agrorecreational ecoparks are researched as structural elements of both agroproductive and recreational complexes of a country. Depending on types of activity there have been established main functional subzones and their interposition according to the exploitation mode and territory security. The planning structure of an agrorecreational ecopark locates the subzones of scientific use in the middle of a park, in the most accessible places as they are main attraction for visitors. Natural landscape of recreational use subzone adjoins the scientific zone; service centers and utility zones are located along the edges of the park thus creating a buffer area. The main groups of relief forms have been analyzed, which directly affect the planning structure of the researched parks. The main types of agrorecreational ecoparks in terms of relief forms have been identified; dimensional and spatial peculiarities of organization of such territories have been determined. In the context of a complex terrain and intensive soil erosion the major component of agrorecreational ecoterritories is geoplastic relief with drainage network (columbine), which determines precipitations run-off and the water regime of the park in general. The main notions and special features of landscape columbine and geoplastics (terracing) have been analyzed. The major types of agrolandscapes under the conditions of agrorecreational ecoparks formation have been established

Удосконалення амортизаційної політики підприємства в світлі нового податкового законодавства

Наук. кер.: О.В. Кубатк

Philosophical comprehension of the formation and development of Ukrainian culture in the context of military realities: the geopolitical aspect

The article examines the impact of war on the process of development of a culture of the Ukrainian people. The purpose of scientific exploration is to analyze the existential and axiological dimensions of Ukrainian folk and national culture under conditions of war. The main objectives are to understand the geopolitical significance of Ukrainian culture in the modern socio-cultural space and to analyze the risks that war brings to the cultural development of Ukraine. The methodological basis of the research is based on general scientific methods of cultural studies: systemic, structural-functional, semiotic, and comparative-historical. In addition, synergetic methodological principles are involved, thanks to which it is possible to form a strategic view of Ukrainian culture in the geopolitical dimension. A promising short-term direction of research of contemporary Ukrainian culture is its axiological transformation, which is an inevitable process under martial law. In addition, the current Russian-Ukrainian war will be another stage in the existential assertion of the culture of the Ukrainian people. So, the war, producing inevitable suffering and destruction in all possible manifestations, simultaneously becomes a kind of border, a new point of reference that gives impetus to the development and renewal of material and spiritual culture

Discourse of disease in Lesia Ukrainka’s epistolary

The article deals with peculiarities of a writer’s experience of long-term illness, the influence of the disease on rhythm, lifestyle and creativity, based on Lesia Ukrainka’s letters of 1883-1913 to relatives, friends, acquaintances, artists, and public figures. It is found out that the internal picture of the disease has been reflected in the letters with the help of the system of writer’s diverse experience, feelings, and emotions. According to the epistolary, Lesia Ukrainka perceived the disease as a yoke, captivity, which prevented her from being proactive, from taking an active part in cultural, artistic, publishing and translation activities. At the same time, the disease built up a discipline, purposefulness of the writer, who worked hard at her educational and intellectual level, in such way cognized her capabilities, outlining the prospects of creativity. The article reveals peculiarities of the disease, changes in the writer’s well-being, focuses on creativity as an active resistance to the disease, as a way of achieving self-esteem. The culture of work and rest, attention to the sick body, her scrupulosity in the performance of medical procedures contributed to the creation of acceptable conditions for creative work, which performed a therapeutic function in the life of the writer

IRISIN KAO PREDIKTOR MIKROALBUMINURIJE U PRETILIH BOLESNIKA S KORONARNOM BOLEŠĆU

Background. Irisin is a recently discovered protein involved in energy homeostasis and glucose metabolism, and is potentially involved in atherosclerosis, obesity, and cardiovascular diseases. The aim of the study was to investigate the irisin effect on microalbuminuria in obese patients with coronary artery disease (CAD). Methods. Sixty-four adult subjects with CAD combined with obesity (59.38% of males), mean age 59.43±10.29 years, were enrolled in the study. Control group included 30 sex- and age-matched subjects. Obese patients with CAD were divided into two groups: group 1 (n=31) without microalbuminuria, and group 2 (n=33) with microalbuminuria. The urine albumin to creatinine ratio (ACR, range 30-300 mL/ mg) indicated microalbuminuria. Specifi c enzyme-linked immunosorbent assay was used for serum irisin measurement. Results. Serum irisin concentrations were signifi cantly different in obese CAD patients with microalbuminuria 121.05 (103.07-133.19) ng/mL and those without it 130.21 (125.21-140.03) ng/mL compared to the control group 147.92 (139.04-172.55) ng/mL (p<0.001), and irisin level was signifi cantly lower in patients with microalbuminuria in comparison with normoalbuminuria (p=0.042). Univariate logistic regression analyses showed irisin to signifi cantly infl uence microalbuminuria (OR: 0.788, 95% CI 0.589-0.967, p=0.011). Multivariable logistic regression analyses revealed that serum irisin remained a signifi cant predictor of microalbuminuria (OR: 0.857, 95% CI 0.561-0.988, p=0.044). Conclusions. Lower irisin levels are an independent predictor of microalbuminuria in patients with CAD combined with obesity. Additional larger longitudinal studies are needed to confirm these findings.Pozadina: Irisin je nedavno otkriveni protein koji sudjeluje u energetskoj homeostazi i metabolizmu glukoze i potencijalno je uključen u aterosklerozu, pretilost, kardiovaskularne bolesti. Cilj studije bio je istražiti učinak irisina na mikroalbuminuriju u pretilih bolesnika s ishemijskom bolesti srca (IBS). Uzorak i metode: 64 odrasla ispitanika s koronarnom bolešću u kombinaciji s pretilošću (59,38 % muškaraca), prosječne dobi 59,43±10,29 godina; 30 ispitanika sastojalo se od kontrola usklađenih po spolu, dobi. Pregledani pretili bolesnici s IBS-om podijeljeni su u dvije skupine. Prva skupina (n=31) bila je bez mikroalbuminurije, a u drugoj su skupini (n=33) bili bolesnici s mikroalbuminurijom. Omjer albumina i kreatinina u mokraći (ACR u rasponu od 30-300 mL/mg) bio je pokazatelj mikroalbuminurije. Za mjerenje irisina u serumu korišten je enzimski imunosorbentni test. Rezultati: Utvrđeno je da se koncentracije irisina u serumu značajno razlikuju u pretilih bolesnika s IBS s mikroalbuminurijom 121.05 (103,07-133,19) ng/mL i bez mikroalbuminurije 130,21 (125,21-140,03) ng/mL u usporedbi s kontrolnom skupinom 147,92 (139,04-172,55) ng/mL, p<0,001, a razina irisina značajno je smanjena u bolesnika s mikroalbuminurijom u usporedbi s normoalbuminurijom, p=0,042. Univarijatne logističke regresijske analize pokazale su da je irisin značajno utjecao na mikroalbuminuriju (OR: 0,788, 95 % CI 0,589-0,967, p=0,011). Više varijabilne logističke regresijske analize otkrile su da je irisin u serumu ostao značajan prediktor mikroalbuminurije (OR: 0,857, 95 % CI 0,561-0,988, p=0,044). Zaključak: Niže razine irisina neovisni su prediktor mikroalbuminurije u bolesnika s koronarnom bolešću u kombinaciji s pretilošću, ali potrebne su daljnje veće longitudinalne studije kako bi se potvrdili ti nalazi

IRISIN KAO PREDIKTOR MIKROALBUMINURIJE U PRETILIH BOLESNIKA S KORONARNOM BOLEŠĆU

Background. Irisin is a recently discovered protein involved in energy homeostasis and glucose metabolism, and is potentially involved in atherosclerosis, obesity, and cardiovascular diseases. The aim of the study was to investigate the irisin effect on microalbuminuria in obese patients with coronary artery disease (CAD). Methods. Sixty-four adult subjects with CAD combined with obesity (59.38% of males), mean age 59.43±10.29 years, were enrolled in the study. Control group included 30 sex- and age-matched subjects. Obese patients with CAD were divided into two groups: group 1 (n=31) without microalbuminuria, and group 2 (n=33) with microalbuminuria. The urine albumin to creatinine ratio (ACR, range 30-300 mL/ mg) indicated microalbuminuria. Specifi c enzyme-linked immunosorbent assay was used for serum irisin measurement. Results. Serum irisin concentrations were signifi cantly different in obese CAD patients with microalbuminuria 121.05 (103.07-133.19) ng/mL and those without it 130.21 (125.21-140.03) ng/mL compared to the control group 147.92 (139.04-172.55) ng/mL (p<0.001), and irisin level was signifi cantly lower in patients with microalbuminuria in comparison with normoalbuminuria (p=0.042). Univariate logistic regression analyses showed irisin to signifi cantly infl uence microalbuminuria (OR: 0.788, 95% CI 0.589-0.967, p=0.011). Multivariable logistic regression analyses revealed that serum irisin remained a signifi cant predictor of microalbuminuria (OR: 0.857, 95% CI 0.561-0.988, p=0.044). Conclusions. Lower irisin levels are an independent predictor of microalbuminuria in patients with CAD combined with obesity. Additional larger longitudinal studies are needed to confirm these findings.Pozadina: Irisin je nedavno otkriveni protein koji sudjeluje u energetskoj homeostazi i metabolizmu glukoze i potencijalno je uključen u aterosklerozu, pretilost, kardiovaskularne bolesti. Cilj studije bio je istražiti učinak irisina na mikroalbuminuriju u pretilih bolesnika s ishemijskom bolesti srca (IBS). Uzorak i metode: 64 odrasla ispitanika s koronarnom bolešću u kombinaciji s pretilošću (59,38 % muškaraca), prosječne dobi 59,43±10,29 godina; 30 ispitanika sastojalo se od kontrola usklađenih po spolu, dobi. Pregledani pretili bolesnici s IBS-om podijeljeni su u dvije skupine. Prva skupina (n=31) bila je bez mikroalbuminurije, a u drugoj su skupini (n=33) bili bolesnici s mikroalbuminurijom. Omjer albumina i kreatinina u mokraći (ACR u rasponu od 30-300 mL/mg) bio je pokazatelj mikroalbuminurije. Za mjerenje irisina u serumu korišten je enzimski imunosorbentni test. Rezultati: Utvrđeno je da se koncentracije irisina u serumu značajno razlikuju u pretilih bolesnika s IBS s mikroalbuminurijom 121.05 (103,07-133,19) ng/mL i bez mikroalbuminurije 130,21 (125,21-140,03) ng/mL u usporedbi s kontrolnom skupinom 147,92 (139,04-172,55) ng/mL, p<0,001, a razina irisina značajno je smanjena u bolesnika s mikroalbuminurijom u usporedbi s normoalbuminurijom, p=0,042. Univarijatne logističke regresijske analize pokazale su da je irisin značajno utjecao na mikroalbuminuriju (OR: 0,788, 95 % CI 0,589-0,967, p=0,011). Više varijabilne logističke regresijske analize otkrile su da je irisin u serumu ostao značajan prediktor mikroalbuminurije (OR: 0,857, 95 % CI 0,561-0,988, p=0,044). Zaključak: Niže razine irisina neovisni su prediktor mikroalbuminurije u bolesnika s koronarnom bolešću u kombinaciji s pretilošću, ali potrebne su daljnje veće longitudinalne studije kako bi se potvrdili ti nalazi

Розробка методу управління конфігурацією продуктів проєкту екологістичної системи

This paper considers the need to transform logistics systems into eco-logistics ones in order to achieve environmental goals of sustainable development. It was determined that one of the ways to reduce the eco-destructive impact of eco-logistics systems on the environment is the use of project management methodology tools and making changes to the project life cycle by including ecologically oriented phases. The products obtained during the life cycle of an eco-logistics system project have been identified and the links between the products of individual phases of the project have been established. The object of this study is the method of managing the configuration of products of the eco-logistics system project, which includes three stages: product parameter specification, product clustering, and structuring of the project’s product clusters. A description of each stage is provided. The specification of product parameters is to create descriptive frame models of products that contain the parameters necessary to characterize the product phase of the project, which are reflected in the content of the project’s products. Product clustering involves the creation of information models of product clusters that contain information about the set of products of the project phases that have close parameter values. Structuring clusters of project products leads to the creation of a network of clusters between which connections are formed, which makes it possible to build a product configuration. Experimental calculations confirming the adequacy of the application of the proposed method of managing the configuration of products of the eco-logistics system project are presented. As a result, a network of clusters of project products has been created, using which makes it possible to synthesize product chains that would have maximum value in terms of complying with eco-logistics rules and could minimize the negative impact on the environment.Висвітлено проблему необхідності перетворення логістичних систем у екологістичні заради досягнення екологічних цілей сталого розвитку. Визначено, що одним зі шляхів зниження екодеструктивного впливу екологістичних системна довкілля є застосування інструментарію методології управління проєктами та внесення змін у життєвий цикл проєкту шляхом включення еколого-орієнтованих фаз. Ідентифіковано продукти, що отримуються на протязі життєвого циклу проєкту екологістичної системи, та визначено зв’язки між продуктами окремих фаз проєкту. Об’єктом дослідження є метод управління конфігурацією продуктів проєкту екологістичної системи, що включає три етапи: специфікацію параметрів продуктів, кластеризацію продуктів, структуризацію кластерів продуктів проєкту. Надано характеристику кожного з етапів. Специфікація параметрів продуктів полягає в створенні описових фреймових моделей продуктів, які містять необхідні для характеристики продукту фази проєкту параметри, що відображаються у змісті продуктів проєкту. Кластеризація продуктів передбачає створення інформаційних моделей кластерів продуктів, які містять інформацію про множину продуктів фаз проєкту, що мають близькі значення параметрів. Структуризація кластерів продуктів проєкту призводить до створення мережі кластерів, між якими утворюються зв’язки, що дозволяє створити конфігурацію продуктів. Представлено експериментальні розрахунки, що підтверджують адекватність застосування запропонованого методу управління конфігурацією продуктів проєкту екологістичної системи. В результаті створено мережу кластерів продуктів проєкту, використовуючи які можливо синтезувати ланцюги продуктів, що матимуть максимальну цінність з погляду виконання правил екологістики та дозволять мінімізувати негативний вплив на довкілл

Взаємозумовленість гіперліпідемії, артеріальної гіпертензії та цукрового діабету іі типу як факторів ризику серцево-судинних захворювань

Концепція профілактики серцево-судинних захворювань (ССЗ) ґрунтується на контролі різних факторів ризику (ФР). Дисліпідемія може мати різний ступінь вираженості за інших ФР, тому метою нашої роботи став пошук асоціацій між кількісними порушеннями ліпідних параметрів крові, а сам рівнем загального холестерину, β-ліпопротеїдів та іншими класичними ФР ССЗ, такими як АГ та ЦД

DIRECTIONS FOR IMPROVING OF THE LABOR MOTIVATIONAL SYSTEM THROUGHT ANALYSIS OF WORKERS’ MOTIVES AND NEEDS AT THE NATIONAL ENTERPRISES

Object of research:&nbsp;the article presents the results of a study conducted by the authors by interviewing employees of industrial enterprises on such important issues as satisfaction with the level of work organization, work performed, motives of job attractiveness, equipment of workplaces, job satisfaction and wages, work motives and the relationship of wages with the final results of work. Solved problem:&nbsp;increasing the level of work motivation by creating motives for attractiveness, job satisfaction and wages of workers at industrial enterprises of Ukraine. Main scientific results:&nbsp;a close connection between value orientations and motives of human activity is proved. The need to improve the system of labor motivation at enterprises, increase employee satisfaction with their work by optimizing the level of wages, creating optimal working conditions, sufficient equipment of workplaces. The existing organization of work does not fully correspond to the manifestation of the abilities of employees and work with full efficiency, only with rare exceptions, most respondents said they were satisfied with the work performed. Scope of practical use of research results:&nbsp;research results can be used for increase of level of motivation of work of workers, perfection of the organization of work, creation of motives of attractiveness, increase of satisfaction with the work and wages of workers at the industrial enterprises of Ukraine. All measures to improve the organization of labor should be primarily aimed at increasing social and creative activity, independence in work. In a market economy, it is not enough just to follow their job descriptions, without initiative and independence. Therefore, the requirements for employees and their qualities are growing