39 research outputs found

    THERAPEUTIC EFFECT OF HARIDRA (CURCUMA LONGA LINN.) IN GENERAL AND ORAL HEALTH- A REVIEW

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    Haridra has been in use for thousands of years as a dye, flavouring and a medicinal herb. Ancient Indian medicine has touted turmeric as an herb with the ability to provide glow and lustre to the skin as well as vigour and vitality to the entire body. In Charaka samhita, Haridra found in Lekhaneeya gana, Kushtaghna, Kandughna, Krimighna, Shirovirechana gana and Sushruta samhita mentioned under Haridradi, Mustadi, Slesmashamana gana. Since turmeric has antimicrobial, antioxidant, astringents and other useful properties, it is quite useful in dentistry also. Curcumin, the most active polyphenolic constituent, is the active ingredient in the traditional herbal remedy and dietary spice turmeric and is obtained from the rhizome Curcuma longa Linn. with a range of beneficial properties, including anti-inflammatory, antioxidant, chemopreventive and chemotherapeutic activity. The pleiotropic activities of curcumin derive from its complex chemistry as well as its ability to influence multiple signalling pathways. The objective of this article is to highlight various uses of turmeric in the dental field

    Short Communication: Effects of temperature on growth, pigment composition and protein content of an Antarctic Cyanobacterium Nostoc commune

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    Tripathi R, Dhuldhaj UP, Singh S. 2012. Short Communication: Effects of temperature on growth, pigment composition and protein content of an Antarctic Cyanobacterium Nostoc commune. Nusantara Bioscience 4: 134-137. Effect of temperature variation on biomass accumulation, pigment composition and protein content were studied for the cyanobacterium Nostoc commune, isolated from Antarctica. Results confirmed the psychrotrophic behavior (optimum growth temperature 25◦C) of the cyanobacterium. Low temperature increased the duration of lag phase and exponential growth phase. Maximum increase in biomass was recorded on 24th day at 25◦C and on 12th day at 50C. The downshift from 25 to 5◦C had almost negligible effect on chl a content. Maximal protein content was recorded for cultures growing at 50C on 12th day. The carotenoids/chl a ratio was maximum (2.48) at 50C on 9th day. It remained almost constant for cultures growing at 5 and 350C. There was an induction in protein synthesis following downshift in temperature from 25 to 5◦C

    Insulin secreting and α-glucosidase inhibitory activity of hexane extract of <i style="mso-bidi-font-style:normal">Annona squamosa</i> Linn. in streptozotocin (STZ) induced diabetic rats

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    623-629The hexane extract of A. squamosa<span style="mso-bidi-font-style: italic"> <span style="mso-bidi-font-weight:bold; mso-bidi-font-style:italic" lang="EN-GB">(ASHE) in 100 and 400 mg/kg body weight dose raised the insulin level when compared with Glimepiride (1 mg/kg) and also inhibited α-glucosidase activity when compared with Acarbose (10 mg/kg) in streptozotocin induced diabetic rats. <span style="mso-bidi-font-weight: bold">The ASHE significantly reduced peak blood glucose (Gp30) and area under curve (AUC) in diabetic rats in oral glucose (OGTT) and oral sucrose (OSTT) tolerance test, but there was more reduction of Gp30 value than AUC in OSTT. Thus, it can be suggested that the ASHE, has hypoglycemic role at 2 levels, i.e. it acts as secretagogue and also inhibits the intestinal enzymes, responsible for glucose metabolism. </span

    Challenges and interventions in well-being among nurses in Psychiatric inpatient care: Literature review

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    The purpose of study is to do a literary review about the nurses working condition in psychiatric care ward and different factors affecting the nurse wellbeing in those work setting which are known to be a nursing field with different challenges with mentally sick patients. In the background, concepts of wellbeing are introduced. It also aims on finding and dis- cussing on possible interventions to ensure the wellbeing of nurse. The research questions are (1) what are factors affecting nurse’s wellbeing in psychiatric care ward? (2) what is possible intervention necessary to ensure wellbeing of nurse in psychiatric ward? Authors have used the human-to-human relationship model by Travelbee as main nursing theory and the Value fulfillment theory a non-nursing theory as a supporting theory as theoretical framework. Literature review is conducted in this study with 17 Articles using qualitative content analysis through inductive approach. Inclusion and exclusion criteria have been used where articles within 10 years from 2011 to 2021 with complete articles and free articles were included which were providing the normal situation of the population not focusing on any particular group of people. Sources of the articles used were PubMed, Science Direct and EBSCO. The findings from the literature review provides many factors affecting the wellbeing of nurses working in psychiatric care ward with many insights with evidence and suggestions for enhancement of nurses. The conclusion of study emphasizes primarily on establishing the good therapeutic relationship among patient and nurse empowering nurses with their personal skills with support of organizational improvements and the de-escalation of violence as second priority which emphasize on good arrangement of security and safe working environment providing well maintained and equipped facilities. The research had own limitations bounded by short time frame and reliance on literatures by other writers in the field, yet it sheds some light on the subject

    Studies on biomarkers for oxidative stress in patients with chronic myeloid leukemia

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    BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative disorder with a unique genetic rearrangement, the Philadelphia chromosome. High reactive oxygen species (ROS) levels favor oxidative stress, which could play a vital role in normal processes and various pathophysiologies including neoplasm. Biomarkers of oxidative stress are measured as products of oxidized proteins and lipids. Plasma levels of protein carbonyl (PC), thiobarbituric acid reactive substances (TBARS) and total lipid hydroperoxide (LOOH) were used as biomarkers of oxidative stress in the past. The aim of this study was to evaluate the products of protein oxidation and lipid peroxidation in plasma as biomarkers of oxidative stress in CML patients. PATIENTS AND METHODS: The study included 40 CML patients and 20 age- and sex-matched healthy volunteers. Of 40 CML patients, 28 were in chronic phase (CML-CP) and 12 in accelerated phase (CML-AP). Plasma levels of PC, TBARS and LOOH as biomarkers of oxidative stress were evaluated by spectrophotometric methods. RESULTS: There were significant differences (P<.05) in plasma levels of PC, TBARS and LOOH in CML, CML-CP and CML-AP patients as compared to controls. CONCLUSION: PC, TBARS and LOOH might reflect oxidative stress in CML patients and might be used as biomarkers in such patients
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