Cosmological Tracking Solutions

A substantial fraction of the energy density of the universe may consist of quintessence in the form of a slowly-rolling scalar field. Since the energy density of the scalar field generally decreases more slowly than the matter energy density, it appears that the ratio of the two densities must be set to a special, infinitesimal value in the early universe in order to have the two densities nearly coincide today. Recently, we introduced the notion of tracker fields to avoid this initial conditions problem. In the paper, we address the following questions: What is the general condition to have tracker fields? What is the relation between the matter energy density and the equation-of-state of the universe imposed by tracker solutions? And, can tracker solutions explain why quintessence is becoming important today rather than during the early universe

Palatini approach to 1/R gravity and its implications to the late Universe

By applying the Palatini approach to the 1/R-gravity model it is possible to explain the present accelerated expansion of the Universe. Investigation of the late Universe limiting case shows that: (i) due to the curvature effects the energy-momentum tensor of the matter field is not covariantly conserved; (ii) however, it is possible to reinterpret the curvature corrections as sources of the gravitational field, by defining a modified energy-momentum tensor; (iii) with the adoption of this modified energy-momentum tensor the Einstein's field equations are recovered with two main modifications: the first one is the weakening of the gravitational effects of matter whereas the second is the emergence of an effective varying "cosmological constant"; (iv) there is a transition in the evolution of the cosmic scale factor from a power-law scaling $a\propto t^{11/18}$ to an asymptotically exponential scaling $a\propto \exp(t)$; (v) the energy density of the matter field scales as $\rho_m\propto (1/a)^{36/11}$; (vi) the present age of the Universe and the decelerated-accelerated transition redshift are smaller than the corresponding ones in the $\Lambda$CDM model.Comment: 5 pages and 2 figures. Accepted in PR

The Tensor to Scalar Ratio of Phantom Dark Energy Models

We investigate the anisotropies in the cosmic microwave background in a class of models which possess a positive cosmic energy density but negative pressure, with a constant equation of state w = p/rho < -1. We calculate the temperature and polarization anisotropy spectra for both scalar and tensor perturbations by modifying the publicly available code CMBfast. For a constant initial curvature perturbation or tensor normalization, we have calculated the final anisotropy spectra as a function of the dark energy density and equation of state w and of the scalar and tensor spectral indices. This allows us to calculate the dependence of the tensor-to-scalar ratio on w in a model with phantom dark energy, which may be important for interpreting any future detection of long-wavelength gravitational waves.Comment: 5 pages, 4 figure

X-ray Reflection By Photoionized Accretion Discs

We present the results of reflection calculations that treat the relevant physics with a minimum of assumptions. The temperature and ionization structure of the top five Thomson depths of an illuminated disc are calculated while also demanding that the atmosphere is in hydrostatic equilibrium. In agreement with Nayakshin, Kazanas & Kallman, we find that there is a rapid transition from hot to cold material in the illuminated layer. However, the transition is usually not sharp so that often we find a small but finite region in Thomson depth where there is a stable temperature zone at T \sim 2 x 10^{6} K due to photoelectric heating from recombining ions. As a result, the reflection spectra often exhibit strong features from partially-ionized material, including helium-like Fe K lines and edges. We find that due to the highly ionized features in the spectra these models have difficulty correctly parameterizing the new reflection spectra. There is evidence for a spurious $R-\Gamma$ correlation in the ASCA energy range, where $R$ is the reflection fraction for a power-law continuum of index $\Gamma$, confirming the suggestion of Done & Nayakshin that at least part of the R-Gamma correlation reported by Zdziarski, Lubinski & Smith for Seyfert galaxies and X-ray binaries might be due to ionization effects. Although many of the reflection spectra show strong ionized features, these are not typically observed in most Seyfert and quasar X-ray spectra.Comment: 16 pages, accepted by MNRAS, Fig. 8 is in colour Figures and tables changed by a code update. Conclusions unchange

Molecular bases determining daptomycin resistance-mediated re-sensitization to β-lactams ("see-saw effect") in MRSA

Antimicrobial resistance is recognized as one of the principal threats to public health worldwide, yet the problem is increasing. Methicillin-resistant Staphylococcus aureus (MRSA) are among the most difficult to treat in clinical settings due to the resistance to nearly all available antibiotics. The cyclic anionic lipopeptide antibiotic Daptomycin (DAP) is the clinical mainstay of anti-MRSA therapy. Decreased susceptibility to DAP (DAPR) reported in MRSA is frequently accompanied with a paradoxical decrease in β-lactam resistance, a process known as the "see-saw" effect. Despite the observed discordance in resistance phenotypes, the combination of DAP/β-lactams has been proven clinically effective for the prevention and treatment of infections due to DAPR-MRSA strains. However, the mechanisms underlying the interactions between DAP and β-lactams are largely unknown. Herein, we studied the role of DAP-induced mutated mprF in β-lactam sensitization and its involvement in the effective killing by the DAP/OXA combination. DAP/OXA-mediated effects resulted in cell-wall perturbations including changes in peptidoglycan (PG) insertion, penicillin-binding protein 2 (PBP2) delocalization and reduced membrane amounts of penicillin-binding protein 2a (PBP2a) contents despite increased transcription of mecA through mec regulatory elements. We have found that the VraSR sensor-regulator is a key component of DAP resistance, triggering mutated mprF-mediated cell membrane (CM) modifications and resulting in impairment of PrsA location and chaperone functions, both essentials for PBP2a maturation, the key determinant of β-lactam resistance. These observations provide first time evidence that synergistic effects between DAP and β-lactams involve PrsA post-transcriptional regulation of CM-associated PBP2a

Constraining the dark energy with galaxy clusters X-ray data

The equation of state characterizing the dark energy component is constrained by combining Chandra observations of the X-ray luminosity of galaxy clusters with independent measurements of the baryonic matter density and the latest measurements of the Hubble parameter as given by the HST key project. By assuming a spatially flat scenario driven by a "quintessence" component with an equation of state $p_x = \omega \rho_x$ we place the following limits on the cosmological parameters $\omega$ and $\Omega_{\rm{m}}$: (i) $-1 \leq \omega \leq -0.55$ and $\Omega_{\rm m} = 0.32^{+0.027}_{-0.014}$ (1$\sigma$) if the equation of state of the dark energy is restricted to the interval $-1 \leq \omega < 0$ (\emph{usual} quintessence) and (ii) $\omega = -1.29^{+0.686}_{-0.792}$ and $\Omega_{\rm{m}} = 0.31^{+0.037}_{-0.034}$ ($1\sigma$) if $\omega$ violates the null energy condition and assume values $< -1$ (\emph{extended} quintessence or ``phantom'' energy). These results are in good agreement with independent studies based on supernovae observations, large-scale structure and the anisotropies of the cosmic background radiation.Comment: 6 pages, 4 figures, LaTe

Genesis of Dark Energy: Dark Energy as Consequence of Release and Two-stage Tracking Cosmological Nuclear Energy

Recent observations on Type-Ia supernovae and low density ($\Omega_{m} = 0.3$) measurement of matter including dark matter suggest that the present-day universe consists mainly of repulsive-gravity type `exotic matter' with negative-pressure often said `dark energy' ($\Omega_{x} = 0.7$). But the nature of dark energy is mysterious and its puzzling questions, such as why, how, where and when about the dark energy, are intriguing. In the present paper the authors attempt to answer these questions while making an effort to reveal the genesis of dark energy and suggest that `the cosmological nuclear binding energy liberated during primordial nucleo-synthesis remains trapped for a long time and then is released free which manifests itself as dark energy in the universe'. It is also explained why for dark energy the parameter $w = - {2/3}$. Noting that $w = 1$ for stiff matter and $w = {1/3}$ for radiation; $w = - {2/3}$ is for dark energy because $"-1"$ is due to `deficiency of stiff-nuclear-matter' and that this binding energy is ultimately released as `radiation' contributing $"+ {1/3}"$, making $w = -1 + {1/3} = - {2/3}$. When dark energy is released free at $Z = 80$, $w = -{2/3}$. But as on present day at $Z = 0$ when radiation strength has diminished to $\delta \to 0$, $w = -1 + \delta{1/3} = - 1$. This, thus almost solves the dark-energy mystery of negative pressure and repulsive-gravity. The proposed theory makes several estimates /predictions which agree reasonably well with the astrophysical constraints and observations. Though there are many candidate-theories, the proposed model of this paper presents an entirely new approach (cosmological nuclear energy) as a possible candidate for dark energy.Comment: 17 pages, 4 figures, minor correction

Chaotic scalar fields as models for dark energy

We consider stochastically quantized self-interacting scalar fields as suitable models to generate dark energy in the universe. Second quantization effects lead to new and unexpected phenomena is the self interaction strength is strong. The stochastically quantized dynamics can degenerate to a chaotic dynamics conjugated to a Bernoulli shift in fictitious time, and the right amount of vacuum energy density can be generated without fine tuning. It is numerically observed that the scalar field dynamics distinguishes fundamental parameters such as the electroweak and strong coupling constants as corresponding to local minima in the dark energy landscape. Chaotic fields can offer possible solutions to the cosmological coincidence problem, as well as to the problem of uniqueness of vacua.Comment: 30 pages, 3 figures. Replaced by final version accepted by Phys. Rev.

Brane oscillations and the cosmic coincidence problem

We show that, under general assumptions, in six-dimensional brane-world models with compactified large extra dimensions, the energy density of brane oscillations scales as that of cold dark matter and its present value is compatible with observations. Such value is obtained from the only dimensional scale in the theory, namely, the fundamental scale of gravity in six dimensions $M_6\sim 1$ TeV, without any fine-tuning or the introduction of additional mass scales apart from the large size of the extra dimensions. It has been suggested that the same kind of models could provide also the correct magnitude of the cosmological constant. This observation can be relevant for the resolution of the cosmic coincidence problem in the brane-world scenario.Comment: 5 pages, RevTeX. Comments on the renormalization of the branon mass included. Final version to appear in Phys.Rev.D (R