Features and drivers of citizen participation: Insights from participatory budgeting in three European cities

Participatory budgeting (PB) is a relatively novel approach to the allocation of funds which allows ordinary citizens to become directly involved in how local government money is spent. This study identifies and examines the features and drivers of PB that incentivize citizen participation and the co-production of public services. Our analysis takes a fresh approach by setting PB initiatives in an innovative frame combining a paradigm of ‘ideal’ types of PB and their diachronic constituent phases. The results provide insights for both scholars and policy makers on the key features and drivers of citizen participation through PB. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

Progress on Neutron-Target Multipoles above 1 GeV

We report a new extraction of nucleon resonance couplings using pi- photoproduction cross sections on the neutron. The world database for the process gn-->pi-p above 1 GeV has quadrupled with the addition of new differential cross sections from the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab in Hall B. Differential cross sections from CLAS have been improved with a new final-state interaction determination using a diagrammatic technique taking into account the SAID phenomenological NN and piN final-state interaction amplitudes. Resonance couplings have been extracted and compared to previous determinations. With the addition of these new cross sections, significant changes are seen in the high-energy behavior of the SAID cross sections and amplitudes.Comment: 4 pages, 3 figures, 1 table; talk given at 12th International Workshop on Meson Production, Properties and Interaction (MESON2012), 31 May - 5 June 2012, Krakow, Poland; will be published online in European Journal Web of Conference

Spectrum of the Y=2 Pentaquarks

By assuming a mass formula for the spectrum of the Y=2 pentaquarks, where the chromo-magnetic interaction plays a main role, and identifying the lightest state with the Theta^+(1540), we predict a spectrum in good agreement with the few I=0 and I=1 candidates proposed in the past.Comment: 12 pages, 4 figures, LaTe

EFEITO DO USO DE INOCULANTES SOBRE O pH E A COMPOSIÇÃO BROMATOLÓGICA DA SILAGEM DE SORGO (Sorghum bicolor L. Moench)

The objective of this work was to study the effect of three doses of commercial bacterial inoculant Sil-All (Alltech®), on the pH and the quality of the silage of sorgo, variety AG 2005. Sixteen experimental silos had been used, with capacity for 20kg of silage. The tested treatments had been T1 without the inoculante addition, T2: 2,5g/L of inoculante, T3: 5,0 g/L of inoculante and T4: 7,5 g/L of inoculante. After 60 days, the silos had been opened and samples removed for determination of pH, PB, FDN and FDA. The delineation was completely randomized, with four treatments and four repetitions. The different applied doses had resulted in significant difference (P 0,05) values of pH, PB, FDN and FDA.O objetivo do presente trabalho foi estudar o efeito de três doses do aditivo bacteriano comercial Sil-All (Alltech®), sobre o pH e a composição bromatológica da silagem de sorgo, variedade AG 2005. Foram utilizados 16 silos experimentais, com capacidade para 20kg de silagem. Os tratamentos testados foram T1: sem a adição de inoculante, T2: 2,5g/L de inoculante, T3: 5,0 g/L de inoculante e T4: 7,5 g/L de inoculante. Após 60 dias de ensilado, os silos foram abertos e retiradas amostras para determinação de pH, PB, FDN e FDA. O delineamento foi inteiramente casualizado, com quatro tratamentos e quatro repetições. As diferentes doses aplicadas resultaram em diferença significativa (P 0,05) os teores de pH, PB, FDN e FDA

CombiROC : an interactive web tool for selecting accurate marker combinations of omics data

Diagnostic accuracy can be improved considerably by combining multiple markers, whose performance in identifying diseased subjects is usually assessed via receiver operating characteristic (ROC) curves. The selection of multimarker signatures is a complicated process that requires integration of data signatures with sophisticated statistical methods. We developed a user-friendly tool, called CombiROC, to help researchers accurately determine optimal markers combinations from diverse omics methods. With CombiROC data from different domains, such as proteomics and transcriptomics, can be analyzed using sensitivity/specificity filters: the number of candidate marker panels rising from combinatorial analysis is easily optimized bypassing limitations imposed by the nature of different experimental approaches. Leaving to the user full control on initial selection stringency, CombiROC computes sensitivity and specificity for all markers combinations, performances of best combinations and ROC curves for automatic comparisons, all visualized in a graphic interface. CombiROC was designed without hard-coded thresholds, allowing a custom fit to each specific data: this dramatically reduces the computational burden and lowers the false negative rates given by fixed thresholds. The application was validated with published data, confirming the marker combination already originally described or even finding new ones. CombiROC is a novel tool for the scientific community freely available at http://CombiROC.eu

miRiadne : a web tool for consistent integration of miRNA nomenclature

The miRBase is the official miRNA repository which keeps the annotation updated on newly discovered miRNAs: it is also used as a reference for the design of miRNA profiling platforms. Nomenclature ambiguities generated by loosely updated platforms and design errors lead to incompatibilities among platforms, even from the same vendor. Published miRNA lists are thus generated with different profiling platforms that refer to diverse and not updated annotations. This greatly compromises searches, comparisons and analyses that rely on miRNA names only without taking into account the mature sequences, which is particularly critic when such analyses are carried over automatically. In this paper we introduce miRiadne, a web tool to harmonize miRNA nomenclature, which takes into account the original miRBase versions from 10 up to 21, and annotations of 40 common profiling platforms from nine brands that we manually curated. miRiadne uses the miRNA mature sequence to link miRBase versions and/or platforms to prevent nomenclature ambiguities. miRiadne was designed to simplify and support biologists and bioinformaticians in re-annotating their own miRNA lists and/or data sets. As Ariadne helped Theseus in escaping the mythological maze, miRiadne will help the miRNA researcher in escaping the nomenclature maze. miRiadne is freely accessible from the URL http://www.miriadne.org

Influencia del manejo del cultivo de maíz sobre el microbioma: implicancias en la pudrición de raíz y tallo

PosterActualmente, una de las principales limitantes para el cultivo de maíz son las enfermedades causadas por hongos. Entre las enfermedades fúngicas reportadas en las últimas campañas se encuentra la pudrición de raíz y tallo (PRT), producida por un complejo de patógenos que habitan en los rastrojos y/o suelo. En los últimos años, esta enfermedad ha incrementado su frecuencia e intensidad, lo cual está asociado a siembras tardías, maíces de segunda y otoños húmedos. Además, el aumento en la densidad de siembra junto con la producción continua del cultivo e inclusión de gramíneas en la secuencia, favorecerían la enfermedad. En este sentido, la intensificación del uso del suelo, implica su progresivo deterioro, generando un desbalance en sus propiedades microbianas, químicas y físicas, lo cual podría explicar el aumento de la incidencia de la enfermedad. Se sabe que algunas prácticas de manejo, como el monocultivo, también tienen efectores estresores sobre el maíz. Por el contrario, la rotación de cultivos, promueve la producción y sanidad de los cultivos principalmente a través de una mejora en las condiciones del suelo (mejor estructura, incremento del contenido de nutrientes, aumento de la biomasa y actividades microbianas, interrupción de los ciclos de los patógenos).Instituto de Patología VegetalFil: Serri, Dannae Lilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Serri, Dannae Lilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Bernardi Lima, Nelson. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Bernardi Lima, Nelson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: De Rossi, R.L. Universidad Católica de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Vargas Gil, Silvina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Vargas Gil, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentin

Informe de Situación Fitosanitaria Región Centro Norte de Córdoba

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progression free survival pfs benefit from first line endocrine based therapies in postmenopausal women with hr her2 metastatic breast cancer mbc according to different prognostic subgroups a combined analysis of data from paloma 2 monaleesa 2 monarch 3 falcon swog and fact trials

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Oxygen equilibrium curve of normal human blood and its evaluation by Adair's equation

Oxygen equilibrium curves of fresh, normal human blood have been measured by new methods which allow the control of pH, pCO2, and 2,3-diphosphoglycerate and which yield higher accuracy at the extremes of saturation than was possible previously. The curve determined by these techniques lies slightly to the right of the standard curve of Roughton et al. (Roughton, F.J.W., Deland, E.C., Kernohan, J.C., and Severinghaus, J.W. (1972) in Oxygen Affinity of Hemoglobin and Red Cell Acid Base Status (Astrup, P., and R\uf8rth, M., eds) pp. 73-83, Academic Press, New York). The greatest difference is at low oxygen saturation, probably owing to the fact that the latter data were obtained under conditions which would lead to depletion of cellular 2,3-diphosphoglycerate. The range of p50 (oxygen pressure at half-saturation) values for four normal subjects was 28.3 mm Hg to 29.0 mm Hg. Adair's stepwise oxygenation scheme has been used to analyze the curves with the result that a1 = 0.1514 X 10(-1) (+/- 10%) mm-1; a2 = 0.9723 X 10(-3) (+/- 8%) mm-2; a3 = 0.1703 X 10(-3) (+/- 50%) mm-3; a4 = 0.1671 X 10(-5) (+/- 2%) mm-4 for the best of four data sets. Because these constants are very sensitive to changes in the shape of the oxygenation curve, this analysis is much more useful than p50 measurements in the investigation of the various allosteric effectors of the function of hemoglobin within the red cell