968 research outputs found

    Luteinizing hormone release and plasma metabolites in mature, ovariectomized beef cows fed various lipid diets

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    Feeding rumen-escape lipid or soybean oil in a range supplement to beef cow resulted in elevated blood cholesterol and enhanced luteinizing hormone (LH) release compared to a control (milo and soybean meal) supplement. Cholesterol was elevated (P<.01) within 14 d of lipid feeding. The amplitude of each LH pulse and maximal pulse height were greater (P<.05) when cows were fed high-lipid diets. The positive influence of high-lipid diets on reproductive function may be explained in part by enhanced LH release

    Quasifree eta photoproduction from nuclei and medium modifications of resonances

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    We investigate the sensitivity of the differential cross section, recoil nucleon polarization and the photon asymmetry to changes in the elementary amplitude, medium modifications of the resonance (S11,D13)(S_{11},D_{13}) masses, as well as nuclear target effects. All calculations are performed within a relativistic plane wave impulse approximation formalism resulting in analytical expressions for all observables. The spin observables are shown to be unique tools to study subtle effects that are not accessible by only looking at the unpolarized differential cross section.Comment: 27 pages, 8 figures, Revtex, To be published in Phys. Rev.

    Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes

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    AbstractBackground and aimsWe investigated whether objectively measured sedentary time was associated with markers of inflammation in adults with newly diagnosed type 2 diabetes.Methods and resultsWe studied 285 adults (184 men, 101 women, mean age 59.0 ± 9.7) who had been recruited to the Early ACTivity in Diabetes (Early ACTID) randomised controlled trial. C-reactive protein (CRP), adiponectin, soluble intracellular adhesion molecule-1 (sICAM-1), interleukin-6 (IL-6), and accelerometer-determined sedentary time and moderate-vigorous physical activity (MVPA) were measured at baseline and after six-months. Linear regression analysis was used to investigate the independent cross-sectional and longitudinal associations of sedentary time with markers of inflammation.At baseline, associations between sedentary time and IL-6 were observed in men and women, an association that was attenuated following adjustment for waist circumference. After 6 months of follow-up, sedentary time was reduced by 0.4 ± 1.2 h per day in women, with the change in sedentary time predicting CRP at follow-up. Every hour decrease in sedentary time between baseline and six-months was associated with 24% (1, 48) lower CRP. No changes in sedentary time between baseline and 6 months were seen in men.ConclusionsHigher sedentary time is associated with IL-6 in men and women with type 2 diabetes, and reducing sedentary time is associated with improved levels of CRP in women. Interventions to reduce sedentary time may help to reduce inflammation in women with type 2 diabetes

    Sex disparities in cardiovascular risk factor assessment and screening for diabetes-related complications in individuals with diabetes: a systematic review

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    Background Insight in sex disparities in the detection of cardiovascular risk factors and diabetes-related complications may improve diabetes care. The aim of this systematic review is to study whether sex disparities exist in the assessment of cardiovascular risk factors and screening for diabetes-related complications.MethodsPubMed was systematically searched up to April 2020, followed by manual reference screening and citations checks (snowballing) using Google Scholar. Observational studies were included if they reported on the assessment of cardiovascular risk factors (HbA1c, lipids, blood pressure, smoking status, or BMI) and/or screening for nephropathy, retinopathy, or performance of feet examinations, in men and women with diabetes separately. Studies adjusting their analyses for at least age, or when age was considered as a covariable but left out from the final analyses for various reasons (i.e. backward selection), were included for qualitative analyses. No meta-analyses were planned because substantial heterogeneity between studies was expected. A modified Newcastle-Ottawa Quality Assessment Scale for cohort studies was used to assess risk of bias.ResultsOverall, 81 studies were included. The majority of the included studies were from Europe or North America (84%).The number of individuals per study ranged from 200 to 3,135,019 and data were extracted from various data sources in a variety of settings. Screening rates varied considerably across studies. For example, screening rates for retinopathy ranged from 13% to 90%, with half the studies reporting screening rates less than 50%. Mixed findings were found regarding the presence, magnitude, and direction of sex disparities with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, with some evidence suggesting that women, compared with men, may be more likely to receive retinopathy screening and less likely to receive foot exams.ConclusionOverall, no consistent pattern favoring men or women was found with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, and screening rates can be improved for both sexes.Public Health and primary carePrevention, Population and Disease management (PrePoD
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