102 research outputs found

    Rapid Stabilization of Sands with Deep Mixing Method Using Polyester

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    Rapid stabilization of weak soils is one of the important and current topics in geotechnical researches such as military application and stabilization of landslides. Deep mixing is an improvement method applied in the form of creating mixed columns which involves in-situ mixing of soil and lime or Portland cement with special equipment. The aim of this study was to evaluate the feasibility of utilizing polymers as a binder for rapid stabilization of sandy soils with deep mixing method. For this purpose, a series of unconfined compression tests were conducted on three dierent sandy soils improved with polyester. In the experiments, polyester was used at three dierent ratios of 10%, 20% and 30% and samples cured for 3 hour, 1, 3, 7 and 28 days. The laboratory test results of 3 hours samples showed that soils mixed with adequate polyester could reach a similar strength range of 28 days cured soils improved with cement or lime which was reported in the literature. The unconfined compressive strength increased with the increasing polyester ratio, effective diameter, and relative density and curing period, whereas, the changes on unconfined compressive strength were insignificant with the increase of freeze-thaw cycles. The overall evaluation of results has revealed that polyester is a good promise and a potential candidate for rapid deep mixing applications

    The effect of activity-related meridional flow modulation on the strength of the solar polar magnetic field

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    We studied the effect of the perturbation of the meridional flow in the activity belts detected by local helioseismology on the development and strength of the surface magnetic field at the polar caps. We carried out simulations of synthetic solar cycles with a flux transport model, which follows the cyclic evolution of the surface field determined by flux emergence and advective transport by near-surface flows. In each hemisphere, an axisymmetric band of latitudinal flows converging towards the central latitude of the activity belt was superposed onto the background poleward meridional flow. The overall effect of the flow perturbation is to reduce the latitude separation of the magnetic polarities of a bipolar magnetic region and thus diminish its contribution to the polar field. As a result, the polar field maximum reached around cycle activity minimum is weakened by the presence of the meridional flow perturbation. For a flow perturbation consistent with helioseismic observations, the polar field is reduced by about 18% compared to the case without inflows. If the amplitude of the flow perturbation depends on the cycle strength, its effect on the polar field provides a nonlinearity that could contribute to limiting the amplitude of a Babcock-Leighton type dynamo.Comment: 16 pages, 5 figures, accepted by Ap

    Data and model driven hybrid approach to activity scoring of cyclic pathways

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    Analysis of large scale -omics data based on a single tool remains inefficient to reveal molecular basis of cellular events. Therefore, data integration from multiple heterogeneous sources is highly desirable and required. In this study, we developed a data- and model-driven hybrid approach to evaluate biological activity of cellular processes. Biological pathway models were taken as graphs and gene scores were transferred through neighbouring nodes of these graphs. An activity score describes the behaviour of a specific biological process was computed by owing of converged gene scores until reaching a target process. Biological pathway model based approach that we describe in this study is a novel approach in which converged scores are calculated for the cellular processes of a cyclic pathway. The convergence of the activity scores for cyclic graphs were demonstrated on the KEGG pathways. © 2011 Springer Science+Business Media B.V

    Designing an intracellular fluorescent probe for glutathione: Two modulation sites for selective signal transduction

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    A selective probe for glutathione was designed and synthesized. The design incorporates spatial and photophysical constraints for the maximal emission signal. Thus, pHs, as well as the intracellular thiol concentrations, determine the emission signal intensity through a tight control of charge-transfer and PeT processes. The probe works satisfactorily inside the human breast adenocarcinoma cells, highlighting GSH distribution in the cytosol. © 2014 American Chemical Society

    European Vegetation Archive (EVA): An integrated database of European vegetation plots

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    © 2016 International Association for Vegetation Science. The European Vegetation Archive (EVA) is a centralized database of European vegetation plots developed by the IAVS Working Group European Vegetation Survey. It has been in development since 2012 and first made available for use in research projects in 2014. It stores copies of national and regional vegetation- plot databases on a single software platform. Data storage in EVA does not affect on-going independent development of the contributing databases, which remain the property of the data contributors. EVA uses a prototype of the database management software TURBOVEG 3 developed for joint management of multiple databases that use different species lists. This is facilitated by the SynBioSys Taxon Database, a system of taxon names and concepts used in the individual European databases and their corresponding names on a unified list of European flora. TURBOVEG 3 also includes procedures for handling data requests, selections and provisions according to the approved EVA Data Property and Governance Rules. By 30 June 2015, 61 databases from all European regions have joined EVA, contributing in total 1 027 376 vegetation plots, 82% of them with geographic coordinates, from 57 countries. EVA provides a unique data source for large-scale analyses of European vegetation diversity both for fundamental research and nature conservation applications. Updated information on EVA is available online at http://euroveg.org/eva-database

    A comparison of a 5% potassium hydroxide solution with a 5-fluorouracil and salicylic acid combination in the treatment of patients with anogenital warts: A randomized, open-label clinical trial

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    Anogenital warts are caused by human papillomavirus (HPV), over 30 types of which are infectious for the anogenital tract. Without treatment, warts may regress spontaneously, remain unchanged, or increase in number and size. This study compared the efficacy of a topical 5% potassium hydroxide (KOH) solution with that of a topical 0.5% 5-fluorouracil (5-FU) and 10% salicylic acid (SA) combination in the treatment of anogenital warts. Sixty patients were randomly assigned to receive topical KOH or 5-FU + SA. Both groups demonstrated a significant decrease in numbers of lesions (P 0.05). The mean number of lesions decreased from baseline to week 12 from 17.03 ± 12.64 to 3.73 ± 7.30 and from 16.13 ± 12.97 to 3.10 ± 4.90 in the KOH and 5-FU + SA groups, respectively (P 0.05). No serious adverse events were reported. Neither treatment was more efficacious. Safety and ease of application are important goals in treatments for anogenital warts. A 5% KOH solution is a promising alternative treatment because it is effective and inexpensive and causes minimal side effects. © 2014 The International Society of Dermatology
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