1,850 research outputs found

    Graduate students navigating social-ecological research: insights from the Long-Term Ecological Research Network

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    Interdisciplinary, collaborative research capable of capturing the feedbacks between biophysical and social systems can improve the capacity for sustainable environmental decision making. Networks of researchers provide unique opportunities to foster social-ecological inquiry. Although insights into interdisciplinary research have been discussed elsewhere, they rarely address the role of networks and often come from the perspectives of more senior scientists. We have provided graduate student perspectives on interdisciplinary degree paths from within the Long-Term Ecological Research (LTER) Network. Focusing on data from a survey of graduate students in the LTER Network and four self-identified successful graduate student research experiences, we examined the importance of funding, pedagogy, research design and development, communication, networking, and culture and attitude to students pursuing social-ecological research. Through sharing insights from successful graduate student approaches to social-ecological research within the LTER Network, we hope to facilitate dialogue between students, faculty, and networks to improve training for interdisciplinary scientists

    Speaking out about gender imbalance in invited speakers improves diversity.

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    Omissions of qualified women scientists from major meeting programs continue to occur despite a surge in articles indicating persistent gender-discriminatory practices in hiring and promotion, and calls for gender balance in conference organizing committees

    Impactos ambientales del ciclo de vida de las baldosas cerámicas: análisis sectorial, identificación de estrategias de mejora y comunicación (I)

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    El artículo analiza el impacto ambiental que generan las baldosas cerámicas mediante el Análisis de Ciclo de Vida (AC) a nivel sectorial en el que participaron más de 50 empresas españolas. Los resultados han servido para la redacción de las Reglas de Categoría de Producto (RCP) para los recubrimientos de materiales cerámicos, necesarias para la edición de Declaraciones Ambientales de Producto. (Debido a la extensión del artículo recogeremos en esta edición la primera parte, correspondiente a la definición de objetivos y alcance del estudio y el análisis del inventario. La segunda parte, que consta de la evaluación de impactos e interpretación, la identificación de estrategias de mejora, la comunicación ambiental y las conclusiones se publicarán en el número 236 de Piscinas XXI).The article analyses the environmental impact of ceramic tiles by means of a sector-level Life Cycle Analysis (LCA) involving over 50 Spanish firms. The findings were then used to draw up the Product Category Rules (PCR) for ceramic coverings, which are needed to be able to issue Environmental Product Declarations. (Due to the length of the paper, in this edition we will include only the first part, which covers the definition of the aims and scope of the study, as well as the inventory analysis. The second part, which comprises the evaluation of the impacts and interpretation, the identification of the improvement strategies, environmental communication and the conclusions, will be published in issue 236 of Piscinas XXI.

    Unfolding-based Diagnosis of Systems with an Evolving Topology

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    We propose a framework for model-based diagnosis of systems with mobility and variable topologies, modelled as graph transformation systems. Generally speaking, model-based diagnosis is aimed at constructing explanations of observed faulty behaviours on the basis of a given model of the system. Since the number of possible explanations may be huge, we exploit the unfolding as a compact data structure to store them, along the lines of previous work dealing with Petri net models. Given a model of a system and an observation, the explanations can be constructed by unfolding the model constrained by the observation, and then removing incomplete explanations in a pruning phase. The theory is formalised in a general categorical setting: constraining the system by the observation corresponds to taking a product in the chosen category of graph grammars, so that the correctness of the procedure can be proved by using the fact that the unfolding is a right adjoint and thus it preserves products. The theory should hence be easily applicable to a wide class of system models, including graph grammars and Petri nets

    Game theory of mind

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    This paper introduces a model of ‘theory of mind’, namely, how we represent the intentions and goals of others to optimise our mutual interactions. We draw on ideas from optimum control and game theory to provide a ‘game theory of mind’. First, we consider the representations of goals in terms of value functions that are prescribed by utility or rewards. Critically, the joint value functions and ensuing behaviour are optimised recursively, under the assumption that I represent your value function, your representation of mine, your representation of my representation of yours, and so on ad infinitum. However, if we assume that the degree of recursion is bounded, then players need to estimate the opponent's degree of recursion (i.e., sophistication) to respond optimally. This induces a problem of inferring the opponent's sophistication, given behavioural exchanges. We show it is possible to deduce whether players make inferences about each other and quantify their sophistication on the basis of choices in sequential games. This rests on comparing generative models of choices with, and without, inference. Model comparison is demonstrated using simulated and real data from a ‘stag-hunt’. Finally, we note that exactly the same sophisticated behaviour can be achieved by optimising the utility function itself (through prosocial utility), producing unsophisticated but apparently altruistic agents. This may be relevant ethologically in hierarchal game theory and coevolution

    Metabolic Profiling of Dividing Cells in Live Rodent Brain by Proton Magnetic Resonance Spectroscopy (1HMRS) and LCModel Analysis

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    RATIONALE: Dividing cells can be detected in the live brain by positron emission tomography or optical imaging. Here we apply proton magnetic resonance spectroscopy (1HMRS) and a widely used spectral fitting algorithm to characterize the effect of increased neurogenesis after electroconvulsive shock in the live rodent brain via spectral signatures representing mobile lipids resonating at approximately 1.30 ppm. In addition, we also apply the same 1HMRS methodology to metabolically profile glioblastomas with actively dividing cells growing in RCAS-PDGF mice. METHODS: 1HMRS metabolic profiles were acquired on a 9.4T MRI instrument in combination with LCModel spectral analysis of: 1) rat brains before and after ECS or sham treatments and 2) RCAS-PDGF mice with glioblastomas and wild-type controls. Quantified 1HMRS data were compared to post-mortem histology. RESULTS: Dividing cells in the rat hippocampus increased approximately 3-fold after ECS compared to sham treatment. Quantification of hippocampal metabolites revealed significant decreases in N-acetyl-aspartate but no evidence of an elevated signal at approximately 1.3 ppm (Lip13a+Lip13b) in the ECS compared to the sham group. In RCAS-PDGF mice a high density (22%) of dividing cells characterized glioblastomas. Nile Red staining revealed a small fraction (3%) of dying cells with intracellular lipid droplets in the tumors of RCAS-PDGF mice. Concentrations of NAA were lower, whereas lactate and Lip13a+Lip13b were found to be significantly higher in glioblastomas of RCAS-PDGF mice, when compared to normal brain tissue in the control mice. CONCLUSIONS: Metabolic profiling using 1HMRS in combination with LCModel analysis did not reveal correlation between Lip13a+Lip13b spectral signatures and an increase in neurogenesis in adult rat hippocampus after ECS. However, increases in Lip13a+Lip13b were evident in glioblastomas suggesting that a higher density of actively dividing cells and/or the presence of lipid droplets is necessary for LCModel to reveal mobile lipids

    The scattering of muons in low Z materials

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    This paper presents the measurement of the scattering of 172 MeV/c muons in assorted materials, including liquid hydrogen, motivated by the need to understand ionisation cooling for muon acceleration. Data are compared with predictions from the Geant 4 simulation code and this simulation is used to deconvolute detector effects. The scattering distributions obtained are compared with the Moliere theory of multiple scattering and, in the case of liquid hydrogen, with ELMS. With the exception of ELMS, none of the models are found to provide a good description of the data. The results suggest that ionisation cooling will work better than would be predicted by Geant 4.7.0p01.Comment: pdfeTeX V 3.141592-1.21a-2.2, 30 pages with 22 figure

    On the Use of Multiple Probe Insertions at the Same Site for Repeated Intracerebral Microdialysis Experiments in the Nigrostriatal Dopamine System of Rats

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    The effects of implantation of a dialysis probe into the striatum of awake rats on indices of dopamine (DA) and serotonin neurotransmission were assessed, first over 24 h following initial insertion of a probe, and then again following reinsertion of a probe at the same site 1 week later. It was found that the basal concentration of DA in dialysate stabilized within 20–40 min after probe implantation, although DA showed a modest decline 24 h later. There was, however, no significant difference in basal DA between two test sessions separated by 1 week. On the other hand, the basal concentrations of the DA metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid, progressively increased for 2–3 h after probe implantation and decreased markedly by 24 h later. Furthermore, in contrast to DA, the DA metabolites decreased even further after the second probe insertion. Amphetamine-stimulated DA release was also greatly attenuated following the second probe insertion, relative to the first probe insertion. Two probe insertions had only modest effects on the concentration of 5-hydroxyindoleacetic acid in dialysate, relative to the DA metabolites. It is suggested the effects of two probe insertions on DA metabolism and amphetamine-stimulated DA release described here are indicative of probe-induced damage to the nigrostriatal DA system. If this is the case, multiple probe insertions may not provide a feasible strategy for within-subjects design dialysis experiments over extended periods of time, at least in the DA system of small animals. It is suggested further that a stable basal concentration of DA in dialysate may be an especially poor indicator of the integrity of the dopaminergic input to the striatum.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65235/1/j.1471-4159.1992.tb10044.x.pd
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