93 research outputs found
Trece años de evaluación compartida en Educación Física
En este trabajo realizamos una revisión de trece años de experiencia docente e investigación educativa sobre la Autoevaluación y la Evaluación Compartida en Educación Física. En una primera parte llevamos a cabo una revisión del estado de la cuestión, describimos el objeto de estudio y la metodología utilizada, para pasar posteriormente a analizar los resultados generales de estos trece años de experimentación. Los resultados los hemos organizado en dos grandes apartados: a-ventajas y posibilidades y b- inconvenientes, dificultades y posibles soluciones, de modo que puedan ser de utilidad para el profesorado interesado en el estudio y la puesta en práctica de este tipo de sistemas de evaluación
Antibacterial Nanostructured Ti Coatings by Magnetron Sputtering: from Laboratory Scales to Industrial Reactors
Based on an already tested laboratory procedure, a new magnetron sputtering methodology to simultaneously coat two-sides of large area implants (up to ~15 cm2) with Ti nanocolumns in industrial reactors has been developed. By analyzing the required growth conditions in a laboratory setup, a new geometry and methodology have been proposed and tested in a semi-industrial scale reactor. A bone plate (Depuy Synthes) and a pseudo-rectangular bone plate extracted from a patient have been coated following the new methodology, obtaining that their osteoblast proliferation efficiency and antibacterial functionality were equivalent to the coatings grown in the laboratory reactor on small areas. In particular, two kinds of experiments have been performed: analysis of bacterial adhesion and biofilm formation, and osteoblasts-bacteria competitive in vitro growth scenarios. In all these cases, the coatings show an opposite behavior towards osteoblast and bacterial proliferation, demonstrating that the proposed methodology represents a valid approach for industrial production and practical application of nanostructured titanium coatings
Sociodemographic, clinical and laboratory factors on admission associated with COVID19 mortality in hospitalized patients: A retrospective observational study
Background
To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain.
Methods and findings
This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital
Universitario Clı´nico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each
patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models.
Series mortality was 25.6%. Among patients with dependence for basic activities of daily
living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per
1-year increase in age; 95%CI 1–6), diabetes mellitus (HR 2.42, 95%CI 1.43–4.09), SatO2/
FiO2 ratio (43% HR reduction per 1-point increase; 95%CI 23–57), SOFA score (19% HR
increase per 1-point increase, 95%CI 5–34) and CURB-65 score (76% HR increase per 1-
point increase, 95%CI 23–143).
Conclusions
The patients residing in retirement homes showed great vulnerability. The main baseline
factors that were independently associated with mortality in patients hospitalized for
COVID-19 were older age, diabetes mellitus, low SatO2/FiO2 ratio, and high SOFA and
CURB-65 scores.Fondos Estructurales de la Union Europea (FEDER)Unit of Excellence on Exercise and Health (UCEES), University of Granad
Nanocolumnar coatings on implants exhibiting antibacterial properties
Trabajo presentado en la 2nd International Conference on Nanomaterials Applied to Life Sciences 2020 (NALS 2020), celebrada en Madrid (España), del 29 al 31 de enero de 2020Addressing the problem of infection from the very first stage, i.e. inhibiting the formation of the
bacterial biofilm, is a crucial step to prevent implant rejection. Nanocolumnar coatings exhibiting
antibacterial properties have been fabricated by oblique deposition with magnetron sputtering [1]. The
formation of nanocolumns (Fig.1) is the result of the effects of atomic shadowing when the atoms reach the
surface along an inclined direction [2]. This technique is environmentally friendly: it is carried out at RT and
does not involve chemical products (no recycling problems). Such methodology have been tested in a semiindustrial scale reactor, successfully coating in a single step the two sides of fixation plates for bone fractures
[3]. Several in vitro experiments have been performed: analysis of bacterial adhesion and biofilm formation,
analysis of osteoblast proliferation and mitochondrial activity, and osteoblasts–bacteria competitive growth
scenarios, the latter also named “Race for the Surface” competition. In all these cases, the coatings show an
opposite behavior toward osteoblast and bacterial proliferation [1,3]. Moreover, they are effective against
Gram positive (S. aureus) and Gram negative (E. coli) bacteria [4]. Finally, when a synergic route is
followed and the coatings are functionalized with Te nanorods, the antibacterial properties are enhanced,
since Te adds contact-killing (Fig. 2), i.e. bactericidal effect, whilst the biocompatibility is preserved [4].MINECO and Fundación Domingo Martínez for funding. J.M.G.-M. thanks the Fulbright Commissio
Revealing the last 13,500 years of environmental history from the multiproxy record of a mountain lake (Lago Enol, northern Iberian Peninsula)
This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s10933-009-9387-7.We present the Holocene sequence from Lago Enol (43°16′N, 4°59′W, 1,070 m a.s.l.), Cantabrian Mountains, northern Spain. A multiproxy analysis provided comprehensive information about regional humidity and temperature changes. The analysis included sedimentological descriptions, physical properties, organic carbon and carbonate content, mineralogy and geochemical composition together with biological proxies including diatom and ostracod assemblages. A detailed pollen study enabled reconstruction of variations in vegetation cover, which were interpreted in the context of climate changes and human impact. Four distinct stages were recognized for the last 13,500 years: (1) a cold and dry episode that includes the Younger Dryas event (13,500–11,600 cal. year BP); (2) a humid and warmer period characterizing the onset of the Holocene (11,600–8,700 cal. year BP); (3) a tendency toward a drier climate during the middle Holocene (8,700–4,650 cal. year BP); and (4) a return to humid conditions following landscape modification by human activity (pastoral activities, deforestation) in the late Holocene (4,650–2,200 cal. year BP). Superimposed on relatively stable landscape conditions (e.g. maintenance of well established forests), the typical environmental variability of the southern European region is observed at this site.The Spanish Inter-Ministry Commission of Science and
Technology (CICYT), the
Spanish National Parks agency, the European Commission, the
Spanish Ministry of Science, and the European
Social Fund
Revealing the last 13,500 years of environmental history from the multiproxy record of a mountain lake (Lago Enol, northern Iberian Peninsula)
This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s10933-009-9387-7.We present the Holocene sequence from Lago Enol (43°16′N, 4°59′W, 1,070 m a.s.l.), Cantabrian Mountains, northern Spain. A multiproxy analysis provided comprehensive information about regional humidity and temperature changes. The analysis included sedimentological descriptions, physical properties, organic carbon and carbonate content, mineralogy and geochemical composition together with biological proxies including diatom and ostracod assemblages. A detailed pollen study enabled reconstruction of variations in vegetation cover, which were interpreted in the context of climate changes and human impact. Four distinct stages were recognized for the last 13,500 years: (1) a cold and dry episode that includes the Younger Dryas event (13,500–11,600 cal. year BP); (2) a humid and warmer period characterizing the onset of the Holocene (11,600–8,700 cal. year BP); (3) a tendency toward a drier climate during the middle Holocene (8,700–4,650 cal. year BP); and (4) a return to humid conditions following landscape modification by human activity (pastoral activities, deforestation) in the late Holocene (4,650–2,200 cal. year BP). Superimposed on relatively stable landscape conditions (e.g. maintenance of well established forests), the typical environmental variability of the southern European region is observed at this site.The Spanish Inter-Ministry Commission of Science and
Technology (CICYT), the
Spanish National Parks agency, the European Commission, the
Spanish Ministry of Science, and the European
Social Fund
On the origins of American Criollo pigs: A common genetic background with a lasting Iberian signature
American Criollo pigs are thought to descend mainly from those imported from the Iberian Peninsula starting in the late 15th century. Criollo pigs subsequently expanded throughout the Americas, adapting to very diverse environments, and possibly receiving influences from other origins. With the intensification of agriculture in the mid-20th century, cosmopolitan breeds largely replaced Criollo pigs, and the few remaining are mostly maintained by rural communities in marginal areas where they still play an important socio-economic and cultural role. In this study, we used 24 microsatellite markers in samples from 1715 pigs representing 46 breeds with worldwide distribution, including 17 American Criollo breeds, with the major focus of investigating their genetic diversity, structure and breed relationships. We also included representatives of the Iberian, Local British, Hungarian, Chinese and Commercial breeds, as well as Wild Boar, in order to investigate their possible influence in the genetic composition of Criollos. Our results show that, when compared with the other breeds, Criollo pigs present higher levels of genetic diversity, both in terms of allelic diversity and expected heterozygosity. The various analyses indicate that breed differentiation overall explains nearly 21% of the total genetic diversity. Criollo breeds showed their own identity and shared a common genetic background, tending to cluster together in various analyses, even though they differ from each other. A close relationship of Criollos with Iberian breeds was revealed by all the different analyses, and the contribution of Iberian breeds, particularly of the Celtic breeds, is still present in various Criollo breeds. No influence of Chinese breeds was detected on Criollos, but a few were influenced by Commercial breeds or by wild pigs. Our results confirm the uniqueness of American Criollo pigs and the role that Iberian breeds have played in their development. © 2021 Revidatti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Observatorio ENRUTA: Procesos de gentrificación, despojo urbano y elitización del espacio en la zona centro de Guadalajara
En el siguiente documento se rescató la experiencia, el aprendizaje y los hallazgos del Proyecto de Aplicación Profesional: Observatorio En Ruta, el cual se basó en una investigación urbana en el centro histórico de Guadalajara con el fin de observar el proceso de gentrificación que gracias a los proyectos urbanísticos de la zona ocurre. Con una metodología de investigación cualitativa se realizó trabajo de campo, análisis documental, seminarios especializados en temáticas urbanas/sociales, entrevistas y documentación audiovisual. El grupo conformado por arquitectos y psicólogas logró tener mayor alcance del Centro histórico de Guadalajara dividiéndolo en cuatro cuadrantes (Refugio, Mezquitan, Santuario y Mercado Corona-Centro) en los que en cada uno existe un proyecto grande que busca rehabilitar y modificar el centro.ITESO, A.C
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