871 research outputs found

    NONLINEAR MONETARY POLICY RULES: SOME NEW EVIDENCE FOR THE US

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    This paper dreives optimal monetary policy rules in setups where certainty equivalence does not hold because either central bank preferences are not quadratic, and/or the aggregate supply relation is nonlinear. Analytical results show that these features lead to sign and size aymmetries, and nonlinearities in the policy rule. Reduced-form estimates indicate that US monetary policy can be characterized by a nonlinear policy rule after 1983, but not before 1979. This finding is consistent with the view that the Fed`s inflation preferences during the Volcker-Greenspan regime differ considerably from the ones during the Burns-Miller regime.

    Short-time critical dynamics at perfect and non-perfect surface

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    We report Monte Carlo simulations of critical dynamics far from equilibrium on a perfect and non-perfect surface in the 3d Ising model. For an ordered initial state, the dynamic relaxation of the surface magnetization, the line magnetization of the defect line, and the corresponding susceptibilities and appropriate cumulant is carefully examined at the ordinary, special and surface phase transitions. The universal dynamic scaling behavior including a dynamic crossover scaling form is identified. The exponent β1\beta_1 of the surface magnetization and β2\beta_2 of the line magnetization are extracted. The impact of the defect line on the surface universality classes is investigated.Comment: 11figure

    Nonlinear Monetary Policy Rules: Some New Evidence for the U.S.

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    This paper derives optimal monetary policy rules in setups where certainty equivalence does not hold because either central bank preferences are not quadratic, and/or the aggregate supply relation is nonlinear. Analytical results show that these features lead to sign and size asymmetries, and nonlinearities in the policy rule. Reduced-form estimates indicate that US monetary policy can be characterized by a nonlinear policy rule after 1983, but not before 1979. This finding is consistent with the view that the Fed's inflation preferences during the Volcker-Greenspan regime differ considerably from the ones during the Burns-Miller regime.Dans cet article, nous dérivons les règles de politique monétaire optimales dans des cadres où \"l'équivalence certaine\" n'est pas satisfaite. On trouve des cas de ce type lorsque, par exemple, les préférences de la banque centrale ne sont pas quadratiques ou lorsque la relation d'offre agrégée n'est pas linéaire. Les résultats théoriques semblent montrer qu'ils peuvent conduire à des asymétries de signe et de niveau et à des nonlinéarités dans la règle de politique. À partir d'estimations de la forme réduite sur données américaines, nous trouvons que la politique monétaire des États-Unis peut être caractérisée par une règle décisionnelle non linéaire après 1983, mais que ce n'est pas le cas avant 1979. Ces résultats reflètent bien la nette différence d'attitude de la Réserve Fédérale face à l'inflation durant les périodes Volcker-Greenspan et Burns-Miller

    Concentrations, Trends, and Air-Water Exchange of PAHs and PBDEs Derived from Passive Samplers in Lake Superior in 2011

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    Polycyclic aromatic hydrocarbons (PAHs) and polybrominated diphenylethers (PBDEs) are both currently released into the environment from anthropogenic activity. Both are hence primarily associated with populated or industrial areas, although wildfires can be an important source of PAHs, too. Polyethylene passive samplers (PEs) were simultaneously deployed in surface water and near surface atmosphere to determine spatial trends and air-water gaseous exchange of 22 PAHs and 11 PBDEs at 19 sites across Lake Superior in 2011. Surface water and atmospheric PAH concentrations were greatest at urban sites (up to 65 ng L-1 and 140 ng m-3, respectively, averaged from June to October). Near populated regions, PAHs displayed net air-to-water deposition, but were near equilibrium off-shore. Retene, probably depositing following major wildfires in the region, dominated dissolved PAH concentrations at most Lake Superior sites. Atmospheric and dissolved PBDEs were greatest near urban and populated sites (up to 6.8 pg L-1 and 15 pg m-3, respectively, averaged from June to October), dominated by BDE-47. At most coastal sites, there was net gaseous deposition of BDE-47, with less brominated congeners contributing to Sault Ste. Marie and eastern open lake fluxes. Conversely, the central open lake and Eagle Harbor sites generally displayed volatilization of PBDEs into the atmosphere, mainly BDE-47

    Surface critical behavior in fixed dimensions d<4d<4: Nonanalyticity of critical surface enhancement and massive field theory approach

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    The critical behavior of semi-infinite systems in fixed dimensions d<4d<4 is investigated theoretically. The appropriate extension of Parisi's massive field theory approach is presented.Two-loop calculations and subsequent Pad\'e-Borel analyses of surface critical exponents of the special and ordinary phase transitions yield estimates in reasonable agreement with recent Monte Carlo results. This includes the crossover exponent Φ(d=3)\Phi (d=3), for which we obtain the values Φ(n=1)0.54\Phi (n=1)\simeq 0.54 and Φ(n=0)0.52\Phi (n=0)\simeq 0.52, considerably lower than the previous ϵ\epsilon-expansion estimates.Comment: Latex with Revtex-Stylefiles, 4 page

    Developing the control system of a syringe infusion pump

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    Infusion pumps have multiple uses according to their location. According to its use, there is a need to control specific parameters. The objective of this work is to implement and to assembly all the modules of an infusion pump, controlling all the functions. The control was implemented with the microcontroller board based Arduino and a webpage was developed to assist the user to record, retrieve and access information about the operating conditions.N/

    Enzymhistochemische Diagnostik gastrointestinaler Motilitätsstörungen: Ein Laborleitfaden

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    Zusammenfassung: Die enzymhistochemischen Reaktionen für Acetylcholinesterase, Laktatdehydrogenase, Succinatdehydrogenase und Nitroxidsynthetase bilden gegenwärtig den Goldstandard zur histologischen Diagnose gastrointestinaler Motilitätsstörungen. Die Acetylcholinesterase-Reaktion stellt cholinerge Nervenfasernetze der Muscularis mucosae und Muscularis propria dar und zeigt deren Acetylcholinesterase-Aktivität an. Laktatdehydrogenase, Succinatdehydrogenase und Nitroxidsynthetase dienen komplementär der selektiven Darstellung der Nervenzellen des Plexus myentericus und submucosus. Diese enzymhistochemischen Techniken erfordern natives Gewebe, sodass der direkte Transport von der gastroenterologischen oder chirurgischen Abteilung zur Pathologie ohne Zeitverzug gewährleistet sein muss. Alternativ können die Biopsien auf Trockeneis an ein weiter entfernt gelegenes Institut versendet werden. Die hier beschriebene Laboranleitung ist über 4Jahrzehnte optimiert und verfeinert worden. Die im Labor optimierten enzymhistochemischen Reaktionen zeichnen sich durch ein höchstes Maß an Zuverlässigkeit und Reproduzierbarkeit aus. Insbesondere für eine interinstitutionelle Vergleichbarkeit der Resultate ist eine standardisierte Methodik unerlässlich. Entsprechend wird in dieser Anleitung eine detaillierte Darstellung der wichtigsten enzymhistochemischen Reaktionen zur Diagnostik gastrointestinaler Motilitätsstörungen gegebe

    Improving Safety of Direct Oral Anticoagulant (DOAC) Dosing in Patients with Severe Chronic and End-Stage Renal Disease

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    The significance of this study is to determine the degree of inconsistency in dosing practice of DOACs at a quaternary care institution such as Thomas Jefferson University Hospital. What is the primary indication for anticoagulation in out population? What percentage is dosed correctly? Are patients primarily over or underdosed

    The magnitude of educational disadvantage amongst indigenous minority groups in Australia.

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    Indigenous groups are amongst the most disadvantaged minority groups in the developed world. This paper examines the educational disadvantage of indigenous Australians by assessing academic performance at a relatively early age. We find that, by the age of 10, indigenous Australians are substantially behind non-indigenous Australians in academic achievement. Their relative performance deteriorates further over the next 2 years. School and locality do not appear to be important determinants of the indigenous to non-indigenous achievement gap. However, geographic remoteness, indigenous ethnicity and language use at home have a marked influence on educational achievement. A current focus of Australian indigenous policy is to increase school resources. Our results suggest that this will not eliminate indigenous educational disadvantage on its own

    Detection of six serotypes of botulinum neurotoxin using fluorogenic reporters

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    Methods that do not require animal sacrifice to detect botulinum neurotoxins (BoNTs) are critical for BoNT antagonist discovery and the advancement of quantitative assays for biodefense and pharmaceutical applications. Here we describe the development and optimization of fluorogenic reporters that detect the proteolytic activity of BoNT/A, B, D, E, F, and G serotypes in real time with femtomolar to picomolar sensitivity. Notably, the reporters can detect femtomolar concentrations of BoNT/A in 4 h and BoNT/E in 20 h, sensitivity that equals that of animal-based methods. The reporters can be used to determine the specific activity of BoNT preparations with intra- and inter-assay coefficients of variation of approximately 10%. Finally, we find that the greater sensitivity of our reporters compared with those used in other commercially available assays makes the former attractive candidates for high-throughput screening of BoNT antagonists
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