2,206 research outputs found

    Clinical haematology of the great bustard (Otis tarda)

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    The haematological parameters of healthy great bustards (Otis tarda L.) have been determined. The values obtained were red cell count (3.0 x 10(12) +/- 0.2 x 10(12/)1), white cell count (33.0 x 10(9) +/- 2.6 x 10(9)/1), haematocrit value (0.51 +/- 0.01 1/1), haemoglobin (13.0 +/- 0.3 g/dl), mean corpuscular volume (178.7 +/- 12.5 fl), mean cell haemoglobin concentration (25.0 +/- 0.6 g/dl), mean corpuscular haemoglobin (42.5 +/- 3.2 pg), differential white cell count: heterophils (22.5 x 10(9) +/- 0.7 x 10(9)/1), lymphocytes (6.0 x 10(9)+/-0.7 x 10(9)/1), eosinophils (2.7 x 10(9) +/- 0.3 x 10(9)/1) and monocytes (1.8 x 10(9)+/-0.2 x 10(9)/1)

    Feasibility of Noninvasive Positive Pressure Ventilation in the Treatment of Oxygen-Dependent COVID-19 Patients in Peru

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    Intensive care is expensive, and availability is limited. Low- and middle-income countries in particular have struggled to cope with the large influx of critically ill patients during the COVID-19 pandemic. Noninvasive respiratory support devices delivering continuous positive airways pressure (CPAP) require less resource and staff expertise compared with invasive mechanical ventilators and can be routinely used outside of intensive care units. This study assessed the use of the UCL-Ventura Wayrachi CPAP device in hospitalized patients with COVID-19 in Peru. A secondary analysis of data collected for a feasibility study commissioned by the Peruvian Ministry of Health was conducted. Data were collected from three hospitals, including patient demographics, clinical data, and outcomes. Forty-five patients were enrolled from July 16 to September 1, 2020. Eight patients (18%) were intolerant of the CPAP mask. Of the remainder, 18 (48.7%) improved and were discharged from hospital after 6 days. Eight (21.6%) died while on CPAP and 11 (29.7%) were eventually intubated, of whom two died. In total, 27 (60%) survived to hospital discharge. Participating physicians noted the device was easy to use and provided patient benefit, though voiced concerns about the strain on hospital oxygen supplies. In conclusion, the UCL Ventura Wayrachi CPAP device proved feasible in COVID-19 patients in Peru, and offered a bridging therapy for patients who required a ventilator when none were available

    Colloidal Quantum Dots-PMMA Waveguides as Integrable Microwave Photonic Phase Shifters

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    “© © 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.”A novel scheme for the control of microwave signals carried at optical wavelengths by use of PbS colloidal quantum dots embedded in PMMA waveguides is presented. When these structures are pumped at wavelengths where PbS has efficient absorption (980 or 1310 nm), a phase shift in a signal carried at 1550 nm is induced. Optimal conditions have been analyzed by studying the influence of the microwave signal and the waveguide structure. In a proof-of-concept experiment, a continuous phase shift up to 35° at 25 GHz has been demonstrated, with good thermal stability (<2° at 25 GHz) when the samples are heated 20 °C above room temperature. The potential benefits of the use of this active-waveguide technology in microwave photonics are due to the continuous scan of the phase delay, its high tuning speed, and its small size, which leads to the possibility of integration.This work was supported in part by the Infraestructura FEDER under Grants UPVOV08-3E-008 and FEDER UPVOV10-3E-492, in part by the Research Excellency Award Program GVA PROMETEO 2013/012, Next generation Microwave Photonic Technologies, and in part by the Spanish MCINN under Projects TEC2011-29120-C05-01, TEC2011-29120-C05-02, and TEC2011-29120-C05-05.Ricchiuti, AL.; Suárez Álvarez, I.; Barrera Vilar, D.; Rodríguez Cantó, PJ.; Fernandez-Pousa, CR.; Abargues, R.; Sales Maicas, S.... (2014). Colloidal Quantum Dots-PMMA Waveguides as Integrable Microwave Photonic Phase Shifters. IEEE Photonics Technology Letters. 26(4):402-404. https://doi.org/10.1109/LPT.2013.2295253S40240426

    Estudio fenológico y caracterización morfológica de variedades tradicionales de manzano y melocotonero

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    Las variedades locales de frutales seleccionadas a lo largo de los años por los agricultores, son muy interesantes para preservar la biodiversidad y los recursos fitogenéticos, ya que presentan unas características organolépticas peculiares y un valor cultural irremplazable. En 2007 se inició un trabajo de recuperación de variedades tradicionales de frutales en Andalucía (Proyecto INIA, RF2007-00027- C06-05) que contempla su prospección, localización, recogida de material vegetal, caracterización morfológica y molecular, multiplicación, documentación y mantenimiento en colección. En este trabajo se han caracterizado morfológicamente mediante caracteres UPOV las flores, hojas y ramos de un año, de cinco variedades tradicionales de manzano (Malus x domestica Borkh.) y dos de melocotonero [Prunus persica (L) Batsch], no estudiadas con anterioridad. Se ha evaluado la floración en la campaña 2011 y se han realizado los fenogramas correspondientesMICINN, INIA y Fondos FEDE

    Leishmania spp. epidemiology of canine leishmaniasis in the Yucatan Peninsula

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    Canine Leishmaniasis is widespread in various Mexican states, where different species of Leishmania have been isolated from dogs. In the present study, we describe the detection of L. braziliensis, L. infantum, and L. mexicana in serum of dogs from the states of Yucatan and Quintana Roo in the Yucatan Peninsula (Mexico). A total of 412 sera were analyzed by ELISA using the total extract of the parasite and the iron superoxide dismutase excreted by different trypanosomatids as antigens. We found the prevalence of L. braziliensis to be 7.52%, L. infantum to be 6.07%, and L. mexicana to be 20.63%, in the dog population studied. The results obtained with ELISA using iron superoxide dismutase as the antigen were confirmed by western blot analysis with its greater sensitivity, and the agreement between the two techniques was very high

    Benchmarking of human Y-chromosomal haplogroup classifiers with whole-genome and whole-exome sequence data

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    In anthropological, medical, and forensic studies, the nonrecombinant region of the human Y chromosome (NRY) enables accurate reconstruction of pedigree relationships and retrieval of ancestral information. Using high-throughput sequencing (HTS) data, we present a benchmarking analysis of command-line tools for NRY haplogroup classification. The evaluation was performed using paired Illumina data from whole-genome sequencing (WGS) and whole-exome sequencing (WES) experiments from 50 unrelated donors. Additionally, as a validation, we also used paired WGS/WES datasets of 54 individuals from the 1000 Genomes Project. Finally, we evaluated the tools on data from third-generation HTS obtained from a subset of donors and one reference sample. Our results show that WES, despite typically offering less genealogical resolution than WGS, is an effective method for determining the NRY haplogroup. Y-LineageTracker and Yleaf showed the highest accuracy for WGS data, classifying precisely 98% and 96% of the samples, respectively. Yleaf outperforms all benchmarked tools in the WES data, classifying approximately 90% of the samples. Yleaf, Y-LineageTracker, and pathPhynder can correctly classify most samples (88%) sequenced with third-generation HTS. As a result, Yleaf provides the best performance for applications that use WGS and WES. Overall, our study offers researchers with a guide that allows them to select the most appropriate tool to analyze the NRY region using both second- and third-generation HTS data

    One-year study of airborne sugar compounds: cross-interpretation with other chemical species and meteorological conditions

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    The daily evolution of seventeen sugar compounds (seven saccharides, seven alcohol-saccharides and three anhydrosaccharides) in atmospheric aerosol samples collected between 9 March 2016 and 14 March 2017 was studied in León (Spain). The main links between the concentration of sugar compounds and various chemical species, pollen, fungal spores and meteorological conditions were investigated. The results showed that, in spring, when high levels of metabolic activity of the plants occur and temperatures increase, glucose, sucrose, 2-methyl-erithritol, mannitol, arabitol and inositol, are significantly correlated with airborne pollen concentrations. Between spring and autumn, Alternaria air concentrations are significantly correlated with temperatures, arabitol and sorbitol + adonitol concentrations. Furthermore, during rainy days, Alternaria is also correlated with mannitol. In autumn, lower temperatures cause an increase in the concentrations of levoglucosan, mannosan and galactosan, probably due to the increased use of domestic heating devices. These anhydrosugars and arabinose, fructose and glucose, are significantly correlated with K, NO3−, EC, OC, Cu, Zn, Se, Pb, V and Ni, while mannosan also correlates with As, showing that these anhydrosaccharides can be emitted from different anthropogenic sources. Precipitation causes an increase in glucose and sucrose concentrations, due to the break of pollen particles that produce hundreds of fine size particles. Besides, precipitation causes an increase in arabitol concentrations, due to the release and growth of fungi.publishe

    Hidradenitis suppurativa: a review

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    Hidradenitis suppurativa (HS) is a chronic inflammatory disorder that is characterized by recurrence, as well as the characteristic location of skin lesions. Patients usually develop very painful inflammatory nodules that generally end in the formation of multiple abscesses and fistulas that typically occur in the skin of the axillary, inguinal, buttock, and perianal folds. It significantly affects the quality of life of patients, leaving physical, economic and psychological sequelae. There is a wide therapeutic arsenal available, but each patient must be individualized and the best possible treatment determined. Early assessment and intensive treatment of the disease can prevent and even avoid significant sequelae and permanent deformities

    Current strategies for the reconstruction of the nipple-areola complex: a review

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    The reconstruction of the nipple-areola complex after a mastectomy is essential for the bio-psycho-social recovery of the patient, it is generally performed 4 to 6 months after surgery and there are multiple surgical reconstruction techniques depending on the experience of the surgeon and of the individual characteristics of the patients. The most widely used for its safety and for having shown the best results is the local flap technique combined with the use of autologous, alloplastic and allograft grafts. However, currently there is still no technique that shows long-term lasting results. For this reason, in this article we describe the five categories of reconstruction techniques for the nipple-areola complex that currently exist, their advantages and disadvantages, as well as the lines of research in tissue engineering in which the world is working to find a therapeutic strategy that can reproduce a nipple-areola complex with the characteristics of the biologic.

    Biodegradable electrospun scaffolds for skin wound regeneration: a review

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    Over the years, skin substitutes have been sought as an alternative for the treatment of different pathologies. In this article, we focus on describing the use of different biodegradable nanofibrillar polymers as skin substitutes in the treatment of acute and chronic wounds, obtained by the electrospinning technique. Electrospinning is a tissue engineering technique used to generate nanofibers of different polymers that are characterized by having a high surface area, low molecular weight, high resistance rates, and nanoporosity, which is why they are particularly interesting for biomedicine, with potential applicability. in the replacement of skin and tubular organs. In this context, the skin created by tissue engineering has high expectations of application in the study of treatment of skin wounds
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