527 research outputs found

    Flight deck engine advisor

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    The focus of this project is on alerting pilots to impending events in such a way as to provide the additional time required for the crew to make critical decisions concerning non-normal operations. The project addresses pilots' need for support in diagnosis and trend monitoring of faults as they affect decisions that must be made within the context of the current flight. Monitoring and diagnostic modules developed under the NASA Faultfinder program were restructured and enhanced using input data from an engine model and real engine fault data. Fault scenarios were prepared to support knowledge base development activities on the MONITAUR and DRAPhyS modules of Faultfinder. An analysis of the information requirements for fault management was included in each scenario. A conceptual framework was developed for systematic evaluation of the impact of context variables on pilot action alternatives as a function of event/fault combinations

    Cholesteric Liquid Crystal Displays as Optical Sensors of Barbiturate Binding

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    The influence on the optical properties of cholesteric liquid crystal displays (LCDs) was examined for neutral molecule binding by mesogen/receptors in the mesomorphic phase. The motivation was to prepare neutral molecule sensors that use a colour change to signal analyte binding. A receptor that binds barbiturate analytes was modified with two or one cholesteryl groups to yield compounds 2 and 3, respectively. LCDs were prepared by incorporating one of the receptor/mesogen compounds into a cholesteric LC blend along with a potential Hbonding guest. The optical properties of the LCDs were then determined by measuring the absorbance of the displays. For various LCDs, the colour of the display depended upon several factors: the amount of guest molecule used, the number of cholesteryl side chains on the receptor and the mole concentration of receptor/mesogen in the blend. In particular, complementary host/guest binding of H-bonding analytes by the bis(cholesteryl) receptor 2 in a cholesteric LCD caused a change of up to +70 nm, which was observed by the naked eye as a blue-to-orange colour change. Control experiments confirm that the colour of an LCD is a consequence of molecular recognition in the mesomorphic phase

    Living at home after emergency hospital admission:prospective cohort study in older adults with and without cognitive spectrum disorder

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    Background: Cognitive spectrum disorders (CSDs) are common in hospitalised older adults and associated with adverse outcomes. Their association with the maintenance of independent living has not been established. The aim was to establish the role of CSDs on the likelihood of living at home 30 days after discharge or being newly admitted to a care home. Methods: A prospective cohort study with routine data linkage was conducted based on admissions data from the acute medical unit of a district general hospital in Scotland. 5570 people aged ≥ 65 years admitted from a private residence who survived to discharge and received the Older Persons Routine Acute Assessment (OPRAA) during an incident emergency medical admission were included. The outcome measures were living at home, defined as a private residential address, 30 days after discharge and new care home admission at hospital discharge. Outcomes were ascertained through linkage to routine data sources. Results: Of the 5570 individuals admitted from a private residence who survived to discharge, those without a CSD were more likely to be living at home at 30 days than those with a CSD (93.4% versus 81.7%; difference 11.7%, 95%CI 9.7–13.8%). New discharge to a care home affected 236 (4.2%) of the cohort, 181 (76.7%) of whom had a CSD. Logistic regression modelling identified that all four CSD categories were associated with a reduced likelihood of living at home and an increased likelihood of discharge to a care home. Those with delirium superimposed on dementia were the least likely to be living at home (OR 0.25), followed by those with dementia (OR 0.43), then unspecified cognitive impairment (OR 0.55) and finally delirium (OR 0.57). Conclusions: Individuals with a CSD are at significantly increased risk of not returning home after hospitalisation, and those with CSDs account for the majority of new admissions to care homes on discharge. Individuals with delirium superimposed on dementia are the most affected. We need to understand how to configure and deliver healthcare services to enable older people to remain as independent as possible for as long as possible and to ensure transitions of care are managed supportively

    Electronic Records Task Force Final Report

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    The University of Minnesota Libraries sponsored the Electronic Records Task Force to explore and develop capacity of the Libraries to preserve and provide access to electronic records. Focusing on the records in the Archives and Special Collections, the Task Force was charged with developing the initial capacity for ingesting and processing electronic records; defining tasks and workflows for staff; and developing ingest and processing workflows. This report documents the work of the Task Force during its first year and recommendations for moving forward. The Task Force members included Lisa Calahan, Kevin Dyke, Lara Friedman-Shedlov, Lisa Johnston, Carol Kussmann (co-chair), Mary Miller, Erik Moore, R. Arvid Nelsen (co-chair), Jon Nichols, Justin Schell, and Mike Sutliff and was sponsored by John Butler and Kris Kiesling

    Climate change and wetland loss impacts on a Western river's water quality

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    An understanding of potential stream water quality conditions under future climate is critical for the sustainability of ecosystems and the protection of human health. Changes in wetland water balance under projected climate could alter wetland extent or cause wetland loss (e.g., via increased evapotranspiration and lower growing season flows leading to reduced riparian wetland inundation) or altered land use patterns. This study assessed the potential climate-induced changes to in-stream sediment and nutrient loads in the snowmelt-dominated Sprague River, Oregon, western US. Additionally, potential water quality impacts of combined changes in wetland water balance and wetland area under future climatic conditions were evaluated. The study utilized the Soil and Water Assessment Tool (SWAT) forced with statistical downscaling of general circulation model (GCM) data from the Coupled Model Intercomparison Project 5 (CMIP5) using the Multivariate Adaptive Constructed Analogs (MACA) method. Our findings suggest that, in the Sprague River, (1) mid-21st century nutrient and sediment loads could increase significantly during the high-flow season under warmer, wetter climate projections or could change only nominally in a warmer and somewhat drier future; (2) although water quality conditions under some future climate scenarios and no wetland loss may be similar to the past, the combined impact of climate change and wetland losses on nutrient loads could be large; (3) increases in stream total phosphorus (TP) concentration with wetland loss under future climate scenarios would be greatest at high-magnitude, low-probability flows; and (4) loss of riparian wetlands in both headwaters and lowlands could increase outlet TP loads to a similar degree, but this could be due to distinctly different mechanisms in different parts of the watershed

    A global surveillance system for crop diseases

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    To satisfy a growing demand for food, global agricultural production must increase by 70% by 2050. However, pests and crop diseases put global food supplies at risk. Worldwide, yield losses caused by pests and diseases are estimated to average 21.5% in wheat, 30.0% in rice, 22.6% in maize, 17.2% in potato, and 21.4% in soybean (1); these crops account for half of the global human calorie intake (2). Climate change and global trade drive the distribution, host range, and impact of plant diseases (3), many of which can spread or reemerge after having been under control (4). Though many national and regional plant protection organizations (NPPOs and RPPOs) work to monitor and contain crop disease outbreaks, many countries, particularly low-income countries (LICs), do not efficiently exchange information, delaying coordinated responses to prevent disease establishment and spread. To improve responses to unexpected crop disease spread, we propose a Global Surveillance System (GSS) that will extend and adapt established biosecurity practices and networking facilities into LICs, enabling countries and regions to quickly respond to emerging disease outbreaks to stabilize food supplies, enhancing global food protection

    Problem formulation by medical students: an observation study

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    <p>Abstract</p> <p>Background</p> <p>Medical problems are often complex and ill-structured. In formulating the problem, one has to discriminate pertinent elements from irrelevant information in order to effectively find a solution. In this observation study, we describe how medical students formulate the problem of a complex case.</p> <p>Methods</p> <p>32 third year medical students were presented with a complex case of endocarditis. They were asked to synthesize the case and give the best formulation of the problem. They were then asked to provide a diagnosis. A subsequent group of 25 students were presented with the problem already formulated and were also asked for the diagnosis. We analyzed the student's problem formulations using the presence or absence of essential elements of the case, the use of higher-order concepts and the use of relations between concepts.</p> <p>Results</p> <p>12/32 students presented with the case made the correct diagnosis. Diagnostic accuracy was significantly associated with the use of higher-order concepts and relations between concepts. Establishing explicit relations was particularly important. Almost all students who missed the diagnosis could not elicit any relations between concepts but only reported factual observations. When presented with an already formulated problem, 19/25 students made the correct diagnosis. (p < 0.05)</p> <p>Conclusion</p> <p>When faced with a complex new case, students may not have the structured knowledge to recognize the nature of the problem. They have to build new schema or problem representation. Our observations suggest that this process involves using higher-order concepts and establishing new relations between concepts. The fact that students could recognize the disease when presented with a formulated problem but had more difficulty when presented with the original complex case indicates that knowledge of the clinical features may be necessary but not sufficient for problem formulation. Our hypothesis is that problem formulation represents a distinct ability.</p

    Volunteerism, social context and health impacts: a qualitative study of Glasgow Commonwealth Games event volunteers

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    Volunteer engagement is crucial to the effective delivery of mega-sporting events. While evidence points to reported motivations and wellbeing benefits for individual participants during and post event, there is less evidence on how this type of civic participation relates to the social context in which it occurs and the wider social determinants of health. This qualitative study sought to understand impacts on wellbeing and the determinants of health resulting from the experience of volunteering at the Glasgow 2014 Commonwealth Games. Focus groups and interviews were conducted one-year post-Games to gather the perspectives of 46 volunteers and 7 unsuccessful applicants on their experiences. Participants provided insight into the volunteer journey, contributions and associated outcomes. Wider social impacts were also reported including a renewed sense of pride in the city. The qualitative analysis suggested an important non-linear relationship between volunteer contributions, impacts and rewards, and the outcome of enhanced social connections. The emergent ‘people and place’ framework identifies some critical factors around city life and volunteer assets that planners could consider in developing and evaluating sustainable volunteering and its wider impacts beyond a mega-event

    Rural+:The plain, the beautiful, the sustainable in rural housing

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    This paper explores the role of landscape aesthetics and sustainability in the development of new rural housing prototypes. Historically, rural building forms were largely influenced by immediately available materials, climate and specific use, resulting in regionally identifiable typologies. Changes in the way we live, proximity to place of work, and the relationship between home, community and land-use have resulted in rural domestic buildings losing specific regional distinctions. The aim of this research is to generate new spatial models of autarkic housing and alternative massing arrangements that respond to local landscape qualities, hybrid land-use, urban densities and local renewable energy production. The outcomes provide, semi-quantifiable spatial development prototypes that integrate these requirements within holistic conceptual frameworks for rural sustainable living providing alternative approaches to addressing Scottish policy legislation and a primer for further research
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