Can social media data be useful in spatial modelling? A case study of ‘museum Tweets’ and visitor flows

This paper explores the potential of volunteered geographical information from social media to inform geographical models of behavior. Based on a case study of museums in Yorkshire, we created a spatial interaction model of visitors to 15 museums from 179 administrative zones to test this potential. Instead of relying on limited official data on the magnitude of flows from different attractions we used volunteered geographic information’ (VGI) to calibrate the model. The method represents the potential of VGI for applications beyond descriptive statistics and visuals and highlights potential uses of georeferenced social media data for geographic models. The main input dataset comprised geo-tagged messages harvested using the Twitter Streaming Application Programming Interface (API). We successfully calibrated the distance decay parameter of the model and conclude that social media data have great potential for aiding models of spatial behavior. However, we also caution that there are dangers associated with the use of social media data. Researchers should weigh up the wider costs and benefits of harnessing such ‘big data’ before blindly harnessing this low quality, high volume resource. Our case study also serves as the basis for discussion of the ethics surrounding the use of privately harvested VGI by publicly funded academics

The politics of judicial independence in the UK's changing constitution

Judicial independence is generally understood as requiring that judges must be insulated from political life. The central claim of this work is that far from standing apart from the political realm, judicial independence is a product of it. It is defined and protected through interactions between judges and politicians. In short, judicial independence is a political achievement. This is the main conclusion of a three-year research project on the major changes introduced by the Constitutional Reform Act 2005, and the consequences for judicial independence and accountability. The authors interviewed over 150 judges, politicians, civil servants and practitioners to understand the day-to-day processes of negotiation and interaction between politicians and judges. They conclude that the greatest threat to judicial independence in future may lie not from politicians actively seeking to undermine the courts, but rather from their increasing disengagement from the justice system and the judiciary

Calibration of a spatial simulation model with volunteered geographical information

For many scientific disciplines, the continued progression of information technology has increased the availability of data, computation and analytical methodologies including simulation and visualisation. Geographical information science is no exception. In this article, we investigate the possibilities for deployment of e-infrastructures to inform spatial planning, analysis and policy-making. We describe an existing architecture that feeds both static and dynamic simulation models from a variety of sources, including not only administrative datasets but also attitudes and behaviours which are harvested online from crowds. This infrastructure also supports visualisation and computationally intensive processing. The main aim of this article is to illustrate how spatial simulation models can be calibrated with crowd-sourced data. We introduce an example in which popular attitudes to congestion charging in a major UK city (Manchester) were collected, with promotional support from a high-profile media organisation (the BBC). These data are used to estimate the parameters of a transport simulation model, using a hungry estimation procedure which is deployed within a high-performance computational grid. We indicate how the resulting model might be used to evaluate the impact of alternative policy options for regulating the traffic in Manchester. Whilst the procedure is novel in itself, we argue that greater credibility could be added by the incorporation of open-source simulation models and by the use of social networking mechanisms to share policy evaluations much more widely

Fish meal supplementation to early lactation Jersey cows grazing ryegrass pasture

This trial was conducted to test the hypothesis that early lactation cows grazing ryegrass pasture and receiving maize and mineral supplementation could respond to additional supplementation with a protein source such as fish meal. Multiparous Jersey cows in early to mid lactation that grazed annual ryegrass pasture in spring were used in a randomised complete block design experiment. In addition to the pasture, cows received 6 kg (as is) of a maize-based supplement, including minerals, fed in two equal portions in the milking parlour. Three groups of 15 cows received a control, a low fish meal or a high fish meal treatment (0, 4 or 8% fish meal replacing maize). Milk yield was measured and milk samples taken fortnightly. A simultaneous study on rumen fermentation was conducted using eight rumen cannulated cows receiving the control and high fish meal treatments in a cross-over design experiment. Ruminal pH and ammonia-N and volatile fatty acid concentrations were measured. Milk yield, 4% fat-corrected milk yield and milk fat and protein percentages of cows on the low and high fish meal treatments (21.9 and 22.1 kg milk/d, 24.1 and 24.2 kg 4% fat corrected milk/d, 4.73 and 4.67% fat and 3.49 and 3.45% protein) were higher than the control (20.5 kg milk/d, 20.4 kg 4% fat corrected milk/d, 3.97% fat and 3.25% protein). The ruminal ammonia-N concentration was higher in the cows on the high fish meal treatment than the control (16.7 vs. 14.2 mg/dL). Fish meal supplementation to cows on ryegrass proved to be profitable. Keywords: Dairy cattle, cultivated pasture, RUP, maize, milk yield, milk composition South African Journal of Animal Science Vol. 38 (4) 2008: pp. 331-34

Transport-Health Equity Outcomes from mobile phone location data - a case study

The digital media convergence has innovated all the information and communication channels. ICTs have adapted to the reticular structure, which can be interpreted as a paradigm of today's Network Society, invoking a reorganization of man-machine relationship, interpersonal interactions and the ways of collecting, processing and storing data. Political communication and its processes of participation are not exempt from this evident change. The aim of this paper is to investigate the transformation dynamics that have taken place through the Internet and social networks, as effectively more democratic tools that are able to stimulate a bottom-up and grassroots participation, in some respects a disintermediate participation compared to the typical unidirectionality of analogue media. In identifying the specific characteristics of the interaction spaces offered by the web, we have examined the digital campaign strategy devised by the political parties during the Italian general election (4th March 2018). The results have returned an unprecedented scenario, in which the social media strategy plays a leading role in the different dimensions of political marketing. The web is proposed to become the ideal social arena for the meeting between political offer and demand

New insights into seasonal foraging ranges and migrations of minke whales from the Salish Sea and coastal British Columbia.

In the Salish Sea and coastal waters of British Columbia, minke whales are known to establish small home ranges during the feeding season. Beyond the feeding season little is known of their movements or distribution. To determine movement patterns of minke whales in these waters we used photo-identification data that were collected opportunistically from 2005-2012. These data were from four non-overlapping areas between 48ºN and 53ºN. Despite year-round search effort, minke whales were only encountered between April and October. Most of the 44 unique minke whales identified in 405 encounters displayed fidelity to areas both within and among feeding seasons. Five of these individuals also made relatively large-scale intra-annual movements between areas on six occasions. They were documented to move up to at least 424km in a northerly direction early in the season and up to at least 398km in a southerly direction late in the season. We believe that the seasonal patterns of these movements provide new insight into the foraging ranges and migrations of individuals. Ecological markers provide further evidence that the minke whales we photographed undertake annual long distance migrations. Scars believed to be from cookiecutter shark bites were observed on 43 individuals and the majority of minke whales documented with good quality images each year had acquired new scars since the previous feeding season. Furthermore, the commensal barnacle Xenobalanus globicipitis was observed on three individuals. Since these sharks and barnacles are from warm waters, it can be inferred that they interacted with the minke whales at lower latitudes. These findings may have important implications for our understanding of minke whale populations in the Salish Sea and the management of this species in the North Pacific

Induction of Endothelial Cell Apoptosis by Solid Tumor Cells

peer reviewedThe mechanisms by which tumor cells extravasate to form metastasis remain controversial. Previous studies performed in vivo and in vitro demonstrate that the contact between tumor cells and the vascular wall impairs endothelium integrity. Here, we investigated the effect of breast adenocarcinoma MCF-7 cells on the apoptosis of human umbilical vein endothelial cells (HUVEC). TUNEL labeling, nuclear morphology, and DNA electrophoresis indicated that MCF-7 cells induced a two- to fourfold increase in HUVEC apoptosis. Caspase-3 activity was significantly enhanced. Neither normal cells tested (mammary epithelial cells, fibroblasts, leukocytes) nor transformed hematopoietic cells tested (HL60, Jurkat) induced HUVEC apoptosis. On the contrary, cells derived from solid tumors (breast adenocarcinoma, MDA-MB-231 and T47D; fibrosarcoma, HT 1080) had an effect similar to that of MCF-7 cells. The induction of apoptosis requires cell-to-cell contact, since it could not be reproduced by media conditioned by MCF-7 cells cultured alone or cocultured with HUVEC. Our results suggest that cells derived from solid tumors may alter the endothelium integrity by inducing endothelial cell apoptosis. On the contrary, normal or malignant leukocytes appear to extravasate by distinct mechanisms and do not damage the endothelium. Our data may lead to a better understanding of the steps involved in tumor cell extravasation

Twitter Watch: Leveraging Social Media to Monitor and Predict Collective-Efficacy of Neighborhoods

Sociologists associate the spatial variation of crime within an urban setting, with the concept of collective efficacy. The collective efficacy of a neighborhood is defined as social cohesion among neighbors combined with their willingness to intervene on behalf of the common good. Sociologists measure collective efficacy by conducting survey studies designed to measure individuals' perception of their community. In this work, we employ the curated data from a survey study (ground truth) and examine the effectiveness of substituting costly survey questionnaires with proxies derived from social media. We enrich a corpus of tweets mentioning a local venue with several linguistic and topological features. We then propose a pairwise learning to rank model with the goal of identifying a ranking of neighborhoods that is similar to the ranking obtained from the ground truth collective efficacy values. In our experiments, we find that our generated ranking of neighborhoods achieves 0.77 Kendall tau-x ranking agreement with the ground truth ranking. Overall, our results are up to 37% better than traditional baselines.Comment: 10 pages, 7 figure

Clinical presentations and outcomes of Filipino juvenile systemic lupus erythematosus

<p>Abstract</p> <p>Objective</p> <p>Juvenile Systemic Lupus Erythematosus (SLE) varies by location and ethnicity. This study describes the clinical, laboratory profile and outcome of juvenile SLE seen at Philippine General Hospital (PGH) from 2004-2008.</p> <p>Method</p> <p>Medical charts of all Filipino Juvenile SLE cases admitted at PGH during the 5-year period were reviewed collecting demographic profile, clinical and laboratory manifestations and treatment during disease course.</p> <p>Results</p> <p>Seventy-eight cases of juvenile SLE were reviewed. There were 7 boys and 71 girls. The mean age at diagnosis was 14 years (SD 2.7) with a range of 8-18 years. Fever (52.5%) and malar rash (41.0%) were the most common features at disease onset. At the time of diagnosis, the most common features were malar rash (65.3%), renal involvement (62.8%) and photosensitivity (55.1%). Mucocutaneous (92.3%), renal (71.7%) and hematologic (69.2%) involvement were the most common features during the entire course of illness. Infection (34.5%) and neurologic (19.0%) complications were observed most frequently. Corticocosteroid treatment was given in most of the patients in the form of prednisone (97.4%) and concomitant methylprednisolone intravenous pulses (29.4%). Nine patients died during the study period. The overall 5-year mortality rate was 11.5%. Infection (77.0%) was the most frequent cause of death.</p> <p>Conclusion</p> <p>Malar rash was a common feature at disease onset and at diagnosis among Filipinos with juvenile SLE. Throughout the disease course, renal involvement occurs in 71.7% of patients. Infection was the leading cause of complication and death. The clinical presentations of Filipinos with juvenile SLE were similar to juvenile SLE in other countries.</p

Chronic arthritis in children and adolescents in two Indian health service user populations

BACKGROUND: High prevalence rates for rheumatoid arthritis, spondyloarthopathies, and systemic lupus erythematosus have been described in American Indian and Alaskan Native adults. The impact of these diseases on American Indian children has not been investigated. METHODS: We used International Classification of Diseases-9 (ICD-9) codes to search two Indian Health Service (IHS) patient registration databases over the years 1998–2000, searching for individuals 19 years of age or younger with specific ICD-9-specified diagnoses. Crude estimates for disease prevalence were made based on the number of individuals identified with these diagnoses within the database. RESULTS: Rheumatoid arthritis (RA) / juvenile rheumatoid arthritis (JRA) was the most frequent diagnosis given. The prevalence rate for JRA in the Oklahoma City Area was estimated as 53 per 100,000 individuals at risk, while in the Billings Area, the estimated prevalence was nearly twice that, at 115 per 100,000. These rates are considerably higher than those reported in the most recent European studies. CONCLUSION: Chronic arthritis in childhood represents an important, though unrecognized, chronic health challenge within the American Indian population living in the United States