56 research outputs found

    Detection of Gamma-rays around 1TeV from RX J0852.0-4622 by CANGAROO-II

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    We have detected gamma-ray emission at the 6sigma level at energies greater than 500GeV from the supernova remnant RX J0852.0-4622 (G266.2-1.2) using the CANGAROO-II Imaging Atmospheric Cherenkov Telescope (IACT). The flux was 0.12 times of that of Crab at 1TeV. The signal centroid is consistent with the peak of the X-ray emission in the north-west rim of the remnant.Comment: 12pages, 4figures, to be published in ApJ

    Intestinal Epithelial-Derived TAK1 Signaling Is Essential for Cytoprotection against Chemical-Induced Colitis

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    We have previously reported that intestinal epithelium-specific TAK1 deleted mice exhibit severe inflammation and mortality at postnatal day 1 due to TNF-induced epithelial cell death. Although deletion of TNF receptor 1 (TNFR1) can largely rescue those neonatal phenotypes, mice harboring double deletion of TNF receptor 1 (TNFR1) and intestinal epithelium-specific deletion of TAK1 (TNFR1KO/TAK1(IE)KO) still occasionally show increased inflammation. This indicates that TAK1 is important for TNF-independent regulation of intestinal integrity.In this study, we investigated the TNF-independent role of TAK1 in the intestinal epithelium. Because the inflammatory conditions were sporadically developed in the double mutant TNFR1KO/TAK1(IE)KO mice, we hypothesize that epithelial TAK1 signaling is important for preventing stress-induced barrier dysfunction. To test this hypothesis, the TNFR1KO/TAK1(IE)KO mice were subjected to acute colitis by administration of dextran sulfate sodium (DSS). We found that loss of TAK1 significantly augments DSS-induced experimental colitis. DSS induced weight loss, intestinal damages and inflammatory markers in TNFR1KO/TAK1(IE)KO mice at higher levels compared to the TNFR1KO control mice. Apoptosis was strongly induced and epithelial cell proliferation was decreased in the TAK1-deficient intestinal epithelium upon DSS exposure. These suggest that epithelial-derived TAK1 signaling is important for cytoprotection and repair against injury. Finally, we showed that TAK1 is essential for interleukin 1- and bacterial components-induced expression of cytoprotective factors such as interleukin 6 and cycloxygenase 2.Homeostatic cytokines and microbes-induced intestinal epithelial TAK1 signaling regulates cytoprotective factors and cell proliferation, which is pivotal for protecting the intestinal epithelium against injury

    CANGAROO-III Search for Gamma Rays from SN 1987A and the Surrounding Field

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    Optical images of SN 1987A show a triple ring structure. The inner (dust) ring has recently increased in brightness and in the number of hot spots suggesting that the supernova shock wave has collided with the dense pre-existing circumstellar medium, a scenario supported by radio and X-ray observations. Such a shocked environment is widely expected to result in the acceleration of charged particles, and the accompanying emission of very high energy gamma-rays. Here, we report the results of observations made in 2004 and 2006 which yield upper limits on the TeV gamma-ray flux, which are compared with a theoretical prediction. In addition, we set upper limits on the TeV flux for four high energy objects which are located within the same field of view of the observation: the super-bubble 30 Dor C, the Crab-like pulsar PSR B0540−-69, the X-ray binary LMC X-1, and the supernova remnant N157B.Comment: 5 pages, 5 figures, Accepted for publication in Ap

    CANGAROO-III Observation of TeV Gamma Rays from the vicinity of PSR B1 706-44

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    Observation by the CANGAROO-III stereoscopic system of the Imaging Cherenkov Telescope has detected extended emission of TeV gamma rays in the vicinity of the pulsar PSR B1706−-44. The strength of the signal observed as gamma-ray-like events varies when we apply different ways of emulating background events. The reason for such uncertainties is argued in relevance to gamma-rays embedded in the "off-source data", that is, unknown sources and diffuse emission in the Galactic plane, namely, the existence of a complex structure of TeV gamma-ray emission around PSR B1706−-44.Comment: 10 pages, 13 figures, to be published in Ap

    Observation of Very High Energy Gamma Rays from HESS J1804-216 with CANGAROO-III Telescopes

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    We observed the unidentified TeV gamma-ray source HESS J1804-216 with the CANGAROO-III atmospheric Cerenkov telescopes from May to July in 2006. We detected very high energy gamma rays above 600 GeV at the 10 sigma level in an effective exposure of 76 hr. We obtained a differential flux of (5.0+/-1.5_{stat}+/-1.6_{sys})\times 10^{-12}(E/1 TeV)^{-\alpha} cm^{-2}s^{-1}TeV^{-1} with a photon index \alpha of 2.69 +/- 0.30_{stat} +/- 0.34_{sys}, which is consistent with that of the H.E.S.S. observation in 2004. We also confirm the extended morphology of the source. By combining our result with multi-wavelength observations, we discuss the possible counterparts of HESS J1804-216 and the radiation mechanism based on leptonic and hadronic processes for a supernova remnant and a pulsar wind nebula.Comment: 11 pages, 12 figures, Accepted in Ap

    Observation of an extended VHE gamma-ray emission from MSH 15-52 with CANGAROO-III

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    We have observed the supernova remnant MSH 15-52 (G320.4-1.2), which contains the gamma-ray pulsar PSR B1509-58, using the CANGAROO-III imaging atmospheric Cherenkov telescope array from April to June in 2006. We detected gamma rays above 810 GeV at the 7 sigma level during a total effective exposure of 48.4 hours. We obtained a differential gamma-ray flux at 2.35 TeV of (7.9+/-1.5_{stat}+/-1.7_{sys}) \times 10^{-13} cm^{-2}s^{-1}TeV^{-1} with a photon index of 2.21+/-0.39_{stat}+/-0.40_{sys}, which is compatible with that of the H.E.S.S. observation in 2004. The morphology shows extended emission compared to our Point Spread Function. We consider the plausible origin of the high energy emission based on a multi-wavelength spectral analysis and energetics arguments.Comment: 9 pages, 9 figures, Accepted in Ap

    CANGAROO-III search for TeV Gamma-rays from two clusters of galaxies

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    Because accretion and merger shocks in clusters of galaxies may accelerate particles to high energies, clusters are candidate sites for the origin of ultra-high-energy (UHE) cosmic-rays. A prediction was presented for gamma-ray emission from a cluster of galaxies at a detectable level with the current generation of imaging atmospheric Cherenkov telescopes. The gamma-ray emission was produced via inverse Compton upscattering of cosmic microwave background (CMB) photons by electron-positron pairs generated by collisions of UHE cosmic rays in the cluster. We observed two clusters of galaxies, Abell 3667 and Abell 4038, searching for very-high-energy gamma-ray emission with the CANGAROO-III atmospheric Cherenkov telescope system in 2006. The analysis showed no significant excess around these clusters, yielding upper limits on the gamma-ray emission. From a comparison of the upper limit for the north-west radio relic region of Abell 3667 with a model prediction, we derive a lower limit for the magnetic field of the region of ~0.1 micro G. This shows the potential of gamma-ray observations in studies of the cluster environment. We also discuss the flux upper limit from cluster center regions using a model of gamma-ray emission from neutral pions produced in hadronic collisions of cosmic-ray protons with the intra-cluster medium (ICM). The derived upper limit of the cosmic-ray energy density within this framework is an order of magnitude higher than that of our Galaxy.Comment: 7 pages, 6 figures, Accepted in Ap

    Search for VHE gamma rays from SS433/W50 with the CANGAROO-II telescope

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    SS433, located at the center of the supernova remnant W50, is a close proximity binary system consisting of a compact star and a normal star. Jets of material are directed outwards from the vicinity of the compact star symmetrically to the east and west. Non-thermal hard X-ray emission is detected from lobes lying on both sides. Shock accelerated electrons are expected to generate sub-TeV gamma rays through the inverse-Compton process in the lobes. Observations of the western X-ray lobe region of SS433/W50 system have been performed to detect sub-TeV gamma-rays using the 10m CANGAROO-II telescope in August and September, 2001, and July and September, 2002. The total observation times are 85.2 hours for ON source, and 80.8 hours for OFF source data. No significant excess of sub-TeV gamma rays has been found at 3 regions of the western X-ray lobe of SS433/W50 system. We have derived 99% confidence level upper limits to the fluxes of gamma rays and have set constraints on the strengths of the magnetic fields assuming the synchrotron/inverse-Compton model for the wide energy range of photon spectrum from radio to TeV. The derived lower limits are 4.3 microgauss for the center of the brightest X-ray emission region and 6.3 microgauss for the far end from SS433 in the western X-ray lobe. In addition, we suggest that the spot-like X-ray emission may provide a major contribution to the hardest X-ray spectrum in the lobe.Comment: 7 pages, 8 figures, to be published in Astroparticle Physic

    CANGAROO-III observation of TeV gamma rays from the unidentified gamma-ray source HESS J1614-518

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    We report the detection, with the CANGAROO-III imaging atmospheric Cherenkov telescope array, of a very high energy gamma-ray signal from the unidentified gamma-ray source HESS J1614-518, which was discovered in the H.E.S.S. Galactic plane survey. Diffuse gamma-ray emission was detected above 760 GeV at the 8.9 sigma level during an effective exposure of 54 hr from 2008 May to August. The spectrum can be represented by a power-law: 8.2+-2.2_{stat}+-2.5_{sys}x10^{-12}x (E/1TeV)^{-Gamma} cm^{-2} s^{-1} TeV^{-1} with a photon index Gamma of 2.4+-0.3_{stat}+-0.2_{sys}, which is compatible with that of the H.E.S.S. observations. By combining our result with multi-wavelength data, we discuss the possible counterparts for HESS J1614-518 and consider radiation mechanisms based on hadronic and leptonic processes for a supernova remnant, stellar winds from massive stars, and a pulsar wind nebula. Although a leptonic origin from a pulsar wind nebula driven by an unknown pulsar remains possible, hadronic-origin emission from an unknown supernova remnant is preferred.Comment: 9 pages, 7 figures, accepted for publication in Ap

    Searches for very high energy gamma rays from blazars with CANGAROO-III telescope in 2005-2009

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    We have searched for very high energy (VHE) gamma rays from four blazars using the CANGAROO-III imaging atmospheric Cherenkov telescope. We report the results of the observations of H 2356-309, PKS 2155-304, PKS 0537-441, and 3C 279, performed from 2005 to 2009, applying a new analysis to suppress the effects of the position dependence of Cherenkov images in the field of view. No significant VHE gamma ray emission was detected from any of the four blazars. The GeV gamma-ray spectra of these objects were obtained by analyzing Fermi/LAT archival data. Non-simultaneous wide range (radio to VHE gamma-ray bands) spectral energy distributions (SEDs) including CANGAROO-III upper limits, GeV gamma-ray spectra, and archival data are discussed using a one-zone synchrotron self-Compton (SSC) model in combination with a external Compton (EC) radiation. The HBLs (H 2356-309 and PKS 2155-304) can be explained by a simple SSC model, and PKS 0537-441 and 3C 279 are well modeled by a combination of SSC and EC model. We find a consistency with the blazar sequence in terms of strength of magnetic field and component size.Comment: 11 pages, 8 figures, Accepted for publication in Astroparticle Physic
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